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Disease Reportsleft ventricular dysfunction
MeSH D018487 - left ventricular dysfunction
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Commercial
Clinical Trials
Competitive landscape
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D018754:Ventricular dysfunction
3 Companies
1 Drug
$
Success rate
D018487: 
Left ventricular dysfunction
94 Companies
27 Drugs
$
Success rate
D054549:Takotsubo cardiomyopathy
0 Companies
0 Drugs
Success rate
Events Timeline
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Commercial
Company Name
Drug Name
Trade Name
Patent Expires
Approval Date
Revenue
Period
TevaBenazepril, Amlodipine besylate Amlodipine Besylate Benazepril  2007-05-18   
Valsartan, Amlodipine besylate Amlodipine Besylate Valsartan  2015-03-30   
Hydrochlorothiazide, Valsartan, Amlodipine besylate Amlodipine Besylate, Valsartan Hydrochlorothiazide  2012-09-25   
Olmesartan medoxomil, Amlodipine besylate Amlodipine Olmesartan Medoxomil  2016-10-26   
Captopril Captopril  1996-02-13   
Hydrochlorothiazide, Captopril Captopril Hydrochlorothiazide  1998-06-18   
Enalapril Enalapril  2000-08-22   
Hydrochlorothiazide, Enalapril Enalapril Hydrochlorothiazide  2003-03-25   
Irbesartan Irbesartan  2012-03-30   
Irbesartan, Hydrochlorothiazide Irbesartan Hydrochlorothiazide  2012-03-30   
Irbesartan Irbesartan Teva  2009-10-30   
Irbesartan, Hydrochlorothiazide Irbesartan/Hydrochlorothiazide Teva  2009-11-26   
Lisinopril Lisinopril  2002-07-01   
Hydrochlorothiazide, Lisinopril Lisinopril Hydrochlorothiazide  2002-07-01   
Losartan potassium Losartan Potassium  2010-04-06   
Hydrochlorothiazide, Losartan potassium Losartan Potassium Hydrochlorothiazide  2010-04-06   
Hydrochlorothiazide, Olmesartan medoxomil, Amlodipine besylate Olmesartan Medoxomil, Amlodipine Hydrochlorothiazide  2016-11-03   
Ramipril Ramipril  2008-06-18   
Trandolapril Trandolapril  2006-12-12   
Valsartan Valsartan  2016-01-04   
Taro PharmaceuticalEnalapril Enalapril  2001-01-23   
Hydrochlorothiazide, Enalapril Enalapril Hydrochlorothiazide  2001-09-18   
Glenmark PharmaceuticalsOlmesartan medoxomil, Amlodipine besylate Amlodipine Olmesartan Medoxomil  2017-07-05   
Verapamil, Trandolapril Trandolapril Verapamil  2010-05-05   
MylanAmlodipine, Valsartan Amlodipine / Valsartan Mylan  2016-03-22   
Benazepril, Amlodipine besylate Amlodipine Besylate Benazepril  2010-05-21   
Valsartan, Amlodipine besylate Amlodipine Besylate Valsartan  2015-03-30   
Candesartan cilexetil Candesartan Cilexetil  2013-05-03   
Hydrochlorothiazide, Candesartan cilexetil Candesartan Cilexetil Hydrochlorothiazide  2012-12-04   
Enalapril Enalapril  2000-08-22   
Irbesartan, Hydrochlorothiazide Irbesartan Hydrochlorothiazide  2012-09-27   
Hydrochlorothiazide, Lisinopril Lisinopril Hydrochlorothiazide  2002-07-01   
Losartan potassium Losartan Potassium  2010-10-06   
Hydrochlorothiazide, Losartan potassium Losartan Potassium Hydrochlorothiazide  2010-04-06   
Telmisartan, Amlodipine besylate Telmisartan Amlodipine  2014-08-26   
Trandolapril Trandolapril  2008-04-28   
Valsartan Valsartan  2015-01-05   
Hydrochlorothiazide, Valsartan Valsartan Hydrochlorothiazide  2012-09-21   
NATCO PharmaRamipril Ramipril  2011-06-30   
Amneal PharmaceuticalsBenazepril, Amlodipine besylate Amlodipine Besylate Benazepril  2018-12-07   
Enalapril Enalapril  2022-06-29   
Irbesartan Irbesartan  2018-04-17   
Valsartan Valsartan  2016-01-11   
Hydrochlorothiazide, Valsartan Valsartan Hydrochlorothiazide  2023-08-11   
CiplaLisinopril Lisinopril  2013-10-29   
Hydrochlorothiazide, Lisinopril Lisinopril Hydrochlorothiazide  2017-05-23   
Ramipril Ramipril  2008-08-07   
Trandolapril Trandolapril  2007-06-12   
Lupin ResearchBenazepril, Amlodipine besylate Amlodipine Besylate Benazepril  2010-02-05   
Valsartan, Amlodipine besylate Amlodipine Besylate Valsartan  2015-03-30   
Hydrochlorothiazide, Valsartan, Amlodipine besylate Amlodipine Besylate, Valsartan Hydrochlorothiazide  2015-06-03   
Irbesartan Irbesartan  2012-10-15   
Irbesartan, Hydrochlorothiazide Irbesartan Hydrochlorothiazide  2013-02-27   
Lisinopril Lisinopril  2005-09-09   
Hydrochlorothiazide, Lisinopril Lisinopril Hydrochlorothiazide  2006-09-27   
Losartan potassium Losartan Potassium  2010-10-06   
Hydrochlorothiazide, Losartan potassium Losartan Potassium Hydrochlorothiazide  2010-05-21   
Ramipril Ramipril  2008-06-09   
Telmisartan, Amlodipine besylate Telmisartan Amlodipine  2014-01-08   
Trandolapril Trandolapril  2007-06-12   
Valsartan Valsartan  2015-01-05   
Hydrochlorothiazide, Valsartan Valsartan Hydrochlorothiazide  2013-03-21   
SandozCaptopril Captopril  1996-02-13   
Enalapril Enalapril  2000-08-22   
Irbesartan Irbesartan  2012-09-27   
Irbesartan, Hydrochlorothiazide Irbesartan Hydrochlorothiazide  2012-09-27   
Hydrochlorothiazide, Lisinopril Lisinopril Hydrochlorothiazide  2002-07-01   
Benazepril, Amlodipine besylate Lotrel  1995-03-03   
Chartwell PharmaceuticalsLosartan potassium Losartan Potassium  2010-10-06   
Hydrochlorothiazide, Losartan potassium Losartan Potassium Hydrochlorothiazide  2010-08-19   
Captopril Captopril  1995-11-09   
Hydrochlorothiazide, Enalapril Enalapril Hydrochlorothiazide  2001-09-19   
Irbesartan Irbesartan  2012-11-14   
Lisinopril Lisinopril  2002-07-01   
Ramipril Ramipril  2008-06-18   
Trandolapril Trandolapril  2007-06-12   
Benazepril, Amlodipine besylate Amlodipine Besylate Benazepril  2010-07-29   
Hydrochlorothiazide, Lisinopril Lisinopril Hydrochlorothiazide  2002-07-01   
Enalapril Enalapril  2000-08-22   
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Clinical Trials
Historical Success Rate
Phase 1
100%
1/1
Phase 2
33%
3/9
Phase 3
61%
17/28
Approved: 17Overall Success rate: 20%
All Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Company name
Phase 1
Phase 2
Phase 3
Phase 4
Drug Name
Teva
Amlodipine besylate,
Benazepril,
Hydrochlorothiazide,
Losartan potassium,
Moexipril,
Ramipril,
Trandolapril
Mylan
Amlodipine,
Amlodipine besylate,
Benazepril,
Hydrochlorothiazide,
Losartan potassium,
Quinapril
Sandoz
Lisinopril
Boehringer Ingelheim
Amlodipine,
Amlodipine besylate,
Hydrochlorothiazide,
Telmisartan
Organon
Hydrochlorothiazide,
Losartan potassium
AbbVie
Hydrochlorothiazide
AstraZeneca
Enalapril,
Felodipine,
Enalaprilat dihydrate,
Angiotensin ii,
Spirolactone,
AZD-1305
Novartis
Aliskiren,
Amlodipine,
Hydrochlorothiazide,
Sacubitril,
Valsartan,
Sacubitril valsartan sodium hydrate,
Amlodipine besylate,
Angiotensin ii
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