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AboutPricing
Drug ReportsMoexipril
Moexipril
Moexipril (moexipril) is a small molecule pharmaceutical. Moexipril was first approved as Univasc on 1995-04-19. It is used to treat diabetic nephropathies, heart failure, hypertension, and left ventricular dysfunction in the USA. The pharmaceutical is active against angiotensin-converting enzyme.
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2Y
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FDA approval date
EMA approval date
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Completion date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
urogenital diseasesD000091642
cardiovascular diseasesD002318
endocrine system diseasesD004700
Trade Name
FDA
EMA
Moexipril (discontinued: Moexipril, Univasc)
Combinations
Moexipril hydrochlorothiazide (discontinued: Moexipril hydrochlorothiazide, Uniretic)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Hydrochlorothiazide
+
Moexipril hydrochloride
Tradename
Company
Number
Date
Products
UNIRETICUCBN-020729 DISCN1997-06-27
3 products
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Moexipril hydrochloride
Tradename
Company
Number
Date
Products
UNIVASCUCBN-020312 DISCN1995-04-19
2 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
moexipril hydrochlorideANDA2025-03-10
univascNew Drug Application2016-02-23
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
heart failureEFO_0003144D006333I50
diabetic nephropathiesEFO_0000401D003928—
hypertensionEFO_0000537D006973I10
left ventricular dysfunction—D018487—
nephrotic syndromeEFO_0004255D009404N04
edema—D004487R60.9
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C09: Agents acting on the renin-angiotensin system
— C09A: Ace inhibitors, plain
— C09AA: Ace inhibitors, plain
— C09AA13: Moexipril
— C09B: Ace inhibitors, combinations
— C09BA: Ace inhibitors and diuretics
— C09BA13: Moexipril and diuretics
HCPCS
No data
Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———2————2
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMoexipril
INNmoexipril
Description
Moexipril is a peptide.
Classification
Small molecule
Drug classantihypertensives (ACE inhibitors)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1Cc2cc(OC)c(OC)cc2C[C@H]1C(=O)O
Identifiers
PDB—
CAS-ID103775-10-6
RxCUI—
ChEMBL IDCHEMBL1165
ChEBI ID6960
PubChem CID91270
DrugBankDB00691
UNII IDWT87C52TJZ (ChemIDplus, GSRS)
Target
Agency Approved
ACE
ACE
Organism
Homo sapiens
Gene name
ACE
Gene synonyms
DCP, DCP1
NCBI Gene ID
1636
Protein name
angiotensin-converting enzyme
Protein synonyms
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1, carboxycathepsin, CD143, CD143 antigen, dipeptidyl carboxypeptidase 1, Dipeptidyl carboxypeptidase I, Kininase II, peptidase P
Uniprot ID
Q7M4L4
Mouse ortholog
Ace (11421)
angiotensin-converting enzyme (P09470)
Alternate
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Moexipril
+
Hydrochlorothiazide
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Price per prescription (USD)
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Moexipril
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 443 documents
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Safety
Black-box Warning
Black-box warning for: Moexipril hydrochloride, Univasc
Adverse Events
Top Adverse Reactions
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101 adverse events reported
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