Therapeutic Area | MeSH |
---|---|
cardiovascular diseases | D002318 |
signs and symptoms pathological conditions | D013568 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
LEXXEL | AstraZeneca | N-020668 DISCN | 1996-12-27 | 2 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
PLENDIL | AstraZeneca | N-019834 DISCN | 1991-07-25 | 3 products, RLD |
Brand Name | Status | Last Update |
---|---|---|
felodipine | ANDA | 2025-03-19 |
felodipine felopdipine | ANDA | 2023-04-04 |
felodipineextended-release tablets | New Drug Application | 2009-09-09 |
felopdipine | ANDA | 2024-08-07 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | 2 | 1 | 3 |
Left ventricular hypertrophy | D017379 | EFO_0003896 | — | — | — | — | 1 | — | 1 |
Hypertrophy | D006984 | EFO_0002460 | — | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Drug common name | Felodipine |
INN | felodipine |
Description | Felodipine is the mixed (methyl, ethyl) diester of 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium-channel blocker, it lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. It is used in the management of hypertension and angina pectoris. It has a role as a calcium channel blocker, an antihypertensive agent, a vasodilator agent and an anti-arrhythmia drug. It is a dihydropyridine, a dichlorobenzene, an ethyl ester and a methyl ester. |
Classification | Small molecule |
Drug class | phenylpyridine vasodilators; tricyclic compounds |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl |
PDB | — |
CAS-ID | 72509-76-3 |
RxCUI | — |
ChEMBL ID | CHEMBL1480 |
ChEBI ID | 585948 |
PubChem CID | 3333 |
DrugBank | DB01023 |
UNII ID | OL961R6O2C (ChemIDplus, GSRS) |