Spirolactone
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304 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart failure | D006333 | EFO_0003144 | I50 | 3 | 10 | 13 | 23 | 20 | 66 |
| Hypertension | D006973 | EFO_0000537 | I10 | 3 | 9 | 7 | 21 | 19 | 59 |
| Fibrosis | D005355 | — | — | — | 3 | 3 | 9 | 6 | 20 |
| Hyperaldosteronism | D006929 | — | E26 | — | — | 1 | 6 | 12 | 19 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | 1 | 10 | 2 | 3 | 4 | 19 |
| Chronic renal insufficiency | D051436 | — | N18 | — | 8 | 1 | 2 | 4 | 14 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | 3 | 3 | 6 | — | 12 |
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | 2 | 2 | 3 | 4 | 11 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 1 | 3 | 3 | 2 | 3 | 11 |
| Cardiomyopathies | D009202 | EFO_0000318 | I42 | 1 | 2 | 1 | 5 | 2 | 11 |
Show 68 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 2 | 3 | — | 3 | 7 |
| Essential hypertension | D000075222 | — | I10 | — | 3 | 1 | — | 2 | 6 |
| Inflammation | D007249 | MP_0001845 | — | 1 | 2 | 1 | — | 3 | 6 |
| Proteinuria | D011507 | — | R80 | — | 1 | 1 | — | 3 | 4 |
| Myocardial infarction | D009203 | EFO_0000612 | I21 | — | — | 3 | — | 1 | 4 |
| Infarction | D007238 | EFO_0009463 | — | — | — | 3 | — | 1 | 4 |
| Acute kidney injury | D058186 | — | N17 | — | 1 | 2 | — | 1 | 4 |
| Wounds and injuries | D014947 | — | T14.8 | — | 1 | 1 | — | 2 | 4 |
| Congenital heart defects | D006330 | — | Q24.9 | — | 2 | 1 | — | 2 | 4 |
| Coronavirus infections | D018352 | EFO_0007224 | B34.2 | — | — | 2 | — | 1 | 3 |
Show 25 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | 4 | 2 | — | — | 3 | 9 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | 1 | — | — | 2 | 3 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | 2 | 2 | — | — | — | 3 |
| Gender identity | D005783 | — | — | 1 | 1 | — | — | 2 | 3 |
| Endocrine system diseases | D004700 | EFO_0001379 | E34.9 | 1 | 1 | — | — | — | 2 |
| Liver diseases | D008107 | EFO_0001421 | K70-K77 | — | 2 | — | — | — | 2 |
| Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | 1 | 2 | — | — | — | 2 |
| Fatty liver | D005234 | EFO_0003934 | — | — | 2 | — | — | — | 2 |
| Univentricular heart | D000080039 | — | Q20.4 | 1 | 1 | — | — | 1 | 2 |
| Arrhythmogenic right ventricular dysplasia | D019571 | Orphanet_247 | I42.8 | — | 1 | — | — | — | 1 |
Show 29 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hyperandrogenism | D017588 | — | — | 3 | — | — | — | 1 | 4 |
| Gender dysphoria | D000068116 | — | F64 | 1 | — | — | — | 2 | 3 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | 1 | — | — | — | 1 | 2 |
| Puberty | D011627 | EFO_0001382 | — | 2 | — | — | — | — | 2 |
| Glucose metabolism disorders | D044882 | — | — | 1 | — | — | — | — | 1 |
| Metabolic diseases | D008659 | EFO_0000589 | E88.9 | 1 | — | — | — | — | 1 |
| Disorders of sex development | D012734 | — | Q56.3 | 1 | — | — | — | — | 1 |
| Melanosis | D008548 | EFO_0003963 | L81.1 | 1 | — | — | — | — | 1 |
| Drug interactions | D004347 | — | — | 1 | — | — | — | — | 1 |
| Takotsubo cardiomyopathy | D054549 | EFO_1002000 | I51.81 | 1 | — | — | — | — | 1 |
Show 6 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypokalemia | D007008 | — | E87.6 | — | — | — | — | 3 | 3 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 3 | 3 |
| Transgenes | D019076 | — | — | — | — | — | — | 3 | 3 |
| Mitral valve insufficiency | D008944 | — | — | — | — | — | — | 3 | 3 |
| Infections | D007239 | EFO_0000544 | — | — | — | — | — | 2 | 2 |
| Menorrhagia | D008595 | EFO_0003945 | N92.0 | — | — | — | — | 2 | 2 |
| Hemophilia a | D006467 | EFO_0007267 | D66 | — | — | — | — | 2 | 2 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | — | 2 | 2 |
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | — | — | — | — | 2 | 2 |
| Sleep initiation and maintenance disorders | D007319 | — | F51.01 | — | — | — | — | 2 | 2 |
Show 89 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | — |
| INN | — |
| Description | — |
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | — |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
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18 adverse events reported
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