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Company ReportsShire

Shire(SHPG)

Shire plc was a UK-founded Jersey-registered specialty biopharmaceutical company. Originating in the United Kingdom with an operational base in the United States, its brands and products included Vyvanse, Lialda, and Adderall XR. Shire was acquired by Takeda Pharmaceutical Company on 8 January 2019.

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Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Anoquan	Acetaminophen, Caffeine, Butalbital	1986-10-01	2025-2039	Pain , Fever , Cough , Postoperative pain , Obstructive lung diseases , Headache , Fatigue , Apnea , Rheumatoid arthritis , Inflammation , Osteoarthritis , Rheumatic fever , Gout , Juvenile arthritis , Menorrhagia , Ankylosing spondylitis , Bursitis , Dysmenorrhea , Premenstrual syndrome , Sinusitis , Asthma , Common cold , Allergic rhinitis perennial , Urticaria , Angioedema
Banthine	Methantheline	1982-01-01		Irritable bowel syndrome , Pancreatitis , Gastritis , Biliary dyskinesia
Dextrostat	Dextroamphetamine	1982-01-01	2023-2042	Narcolepsy , Attention deficit disorder with hyperactivity
Dopar	Levodopa	1982-01-01	2023-2039	Parkinson disease
Dynepo	Epoetin delta	2002-03-18		Chronic kidney failure, Anemia
Ethmozine	Moricizine	1990-06-19		Ventricular tachycardia, Cardiac arrhythmias, Ventricular fibrillation
Furacin	Nitrofurazone	1982-01-01		Staphylococcal skin infections, Escherichia coli infections, Wound infection, Clostridium infections, Streptococcal infections, Burns, Proteus infections
Furoxone	Furazolidone	1982-01-01		Diarrhea, Cholera, Escherichia coli infections, Bacillary dysentery, Giardiasis, Staphylococcal infections, Proteus infections, Enteritis, Animal salmonella infections
Oby-trim	Phentermine	1982-03-18	2028-2029	Obesity, Pain, Epilepsy, Lennox gastaut syndrome, Infantile spasms, Partial epilepsies, Tonic-clonic epilepsy, Bipolar disorder
Pro-banthine	Propantheline	1982-01-01		Irritable bowel syndrome, Pancreatitis, Peptic ulcer, Urinary bladder diseases, Spasm, Urethral diseases
Saluron	Hydroflumethiazide	1982-01-01		Heart failure, Hypertension, Glomerulonephritis, Liver cirrhosis, Nephrotic syndrome, Edema, Dyskinesias, Schizophrenia
Salutensin-demi	Hydroflumethiazide, Reserpine	1982-01-01		Heart failure, Hypertension, Glomerulonephritis, Liver cirrhosis, Nephrotic syndrome, Edema, Dyskinesias, Schizophrenia

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Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Dextroamphetamine

,

pediatric obesity

,

cocaine-related disorders

,

healthy volunteers/patients

,

opioid-related disorders

,

,

amphetamine-related disorders

,

,

addictive behavior

,

psychotic disorders

,

,

idiopathic hypersomnia

,

disorders of excessive somnolence

,

sleep deprivation

,

,

bulimia nervosa

,

multiple sclerosis

,

,

,

,

neurotoxicity syndromes

,

bariatric surgery

,

,

adolescent development

,

post-traumatic stress disorders

,

traumatic stress disorders

,

diabetes mellitus

,

type 1 diabetes mellitus

,

,

binge-eating disorder

,

,

,

,

,

attention deficit disorder with hyperactivity

,

,

depressive disorder

,

,

substance-related disorders

,

major depressive disorder

,

feeding and eating disorders

,

,

bipolar disorder

,

cognitive dysfunction

,

autism spectrum disorder

,

,

autistic disorder

,

traumatic brain injuries

,

,

conduct disorder

,

glucose intolerance

,

,

problem behavior

,

wounds and injuries

,

,

,

,

anxiety disorders

,

chronic fatigue syndrome

,

treatment-resistant depressive disorder

,

alzheimer disease

,

,

attention deficit and disruptive behavior disorders

,

oppositional defiant disorder

,

fetal alcohol spectrum disorders

,

post-acute covid-19 syndrome

,

tobacco use disorder

,

,

,

,

,

,

,

,

coronavirus infections

,

,

,

,

,

,

blood coagulation disorders

,

mucocutaneous lymph node syndrome

,

hyperaldosteronism

,

pulmonary arterial hypertension

,

urinary tract infections

,

hyperphosphatemia

,

,

,

sleep initiation and maintenance disorders

,

,

cardiac arrhythmias

,

bronchopulmonary dysplasia

,

adrenal insufficiency

,

,

communicable diseases

,

hemostatic disorders

,

,

coagulation protein disorders

,

heroin dependence

,

mental disorders

,

obsessive-compulsive disorder

,

compulsive personality disorder

,

,

patient dropouts

,

metabolic diseases

,

metabolic syndrome

,

marijuana abuse

,

feeding behavior

,

,

,

,

female infertility

,

transcranial direct current stimulation

,

alcohol drinking

Dextroamphetamine saccharate

,

attention deficit disorder with hyperactivity

healthy volunteers/patients

,

chronic renal insufficiency

,

chronic kidney failure

,

renal insufficiency

,

kidney diseases

,

,

,

healthy volunteers/patients

,

type 2 diabetes mellitus

,

,

,

,

,

respiratory syncytial virus infections

,

brain neoplasms

,

non-small-cell lung carcinoma

,

central nervous system neoplasms

,

,

glucose metabolism disorders

,

metabolic diseases

,

alzheimer disease

,

huntington disease

,

sickle cell anemia

,

atopic dermatitis

,

anxiety disorders

,

prostatic neoplasms

,

colorectal neoplasms

,

breast neoplasms

,

,

adenocarcinoma of lung

,

generalized anxiety disorder

,

reflex epilepsy

,

bipolar disorder

,

diabetes mellitus

,

,

status epilepticus

,

critical illness

,

,

psychomotor agitation

,

post-traumatic stress disorders

,

executive function

,

,

partial epilepsies

,

generalized epilepsy

,

complex partial epilepsy

,

,

insulin resistance

,

metabolic syndrome

,

,

major depressive disorder

,

depressive disorder

,

psychotic disorders

,

gastrointestinal endoscopy

,

hyperlipidemias

,

type 2 diabetes mellitus

,

,

,

hiv-associated lipodystrophy syndrome

,

,

healthy volunteers/patients

,

ulcerative colitis

,

,

,

,

pulmonary edema

,

,

,

acquired immunodeficiency syndrome

,

communicable diseases

,

,

,

,

depressive disorder

uterine cervical neoplasms

,

,

,

,

,

diabetic neuropathies

,

bipolar disorder

,

severe acute respiratory syndrome-related coronavirus

,

risk reduction behavior

,

blood coagulation disorders

,

hemostatic disorders

,

gastrointestinal microbiome

,

therapeutic equivalency

,

bacillary dysentery

,

metabolic bone diseases

,

adenocarcinoma of lung

,

large cell carcinoma

,

middle east respiratory syndrome coronavirus

,

hepatic insufficiency

,

viral hepatitis human

,

overactive urinary bladder

,

,

,

surgical amputation

,

traumatic amputation

,

prosthesis fitting

,

duchenne muscular dystrophy

,

muscular dystrophies

,

,

adenosquamous carcinoma

,

vaginal neoplasms

,

,

,

abdominal hernia

,

,

,

small cell lung carcinoma

,

hypercholesterolemia

,

,

magnetic resonance imaging

,

,

feeding and eating disorders

,

,

,

digestive system neoplasms

,

merkel cell carcinoma

,

west nile fever

,

transcranial magnetic stimulation

,

,

hidradenitis suppurativa

,

,

,

pancreatic neoplasms

,

multiple myeloma

,

,

diabetes mellitus

,

non-hodgkin lymphoma

,

large b-cell lymphoma diffuse

,

type 2 diabetes mellitus

,

myelodysplastic syndromes

,

ovarian neoplasms

,

,

hematologic neoplasms

,

,

plasma cell neoplasms

,

ovarian epithelial carcinoma

,

type 1 diabetes mellitus

,

,

pancreatic ductal carcinoma

,

castration-resistant prostatic neoplasms

,

rheumatoid arthritis

,

parkinson disease

,

alzheimer disease

,

obsessive-compulsive disorder

,

myelomonocytic leukemia chronic

,

myeloid leukemia

,

primary myelofibrosis

,

renal cell carcinoma

,

cholangiocarcinoma

,

liver neoplasms

,

biphenotypic leukemia acute

,

germ cell and embryonal neoplasms

,

,

bcr-abl positive chronic myelogenous leukemia

,

schistosomiasis

,

,

brain neoplasms

,

,

myeloid leukemia chronic-phase

,

head and neck neoplasms

,

multiple sclerosis

,

autoimmune diseases

,

b-cell lymphoma

,

atopic dermatitis

,

follicular lymphoma

,

biliary tract neoplasms

,

,

,

,

myeloproliferative disorders

,

fallopian tube neoplasms

,

gastrointestinal neoplasms

,

myeloid leukemia accelerated phase

,

refractory anemia with excess of blasts

,

large-cell lymphoma anaplastic

,

primitive neuroectodermal tumors

,

neuroectodermal tumors

,

,

,

,

,

,

congenital heart defects

,

metabolic diseases

,

,

primary immunodeficiency diseases

,

urologic neoplasms

,

general anesthesia

,

kidney neoplasms

,

solitary pulmonary nodule

,

cigarette smoking

,

,

schistosomiasis mansoni

,

mental disorders

,

,

,

gallbladder neoplasms

,

falciparum malaria

,

,

alcoholic liver cirrhosis

,

,

,

pathologic processes

,

myelomonocytic leukemia acute

,

myelomonocytic leukemia juvenile

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

uveal neoplasms

,

rectal neoplasms

,

clonal hematopoiesis

,

myelodysplastic-myeloproliferative diseases

,

hematopoietic stem cell transplantation

,

,

nervous system diseases

,

autoimmune diseases of the nervous system

,

autologous transplantation

,

neuromyelitis optica

,

myasthenia gravis

,

ocular motility disorders

,

polyneuropathies

,

muscle weakness

,

,

stiff-person syndrome

,

central nervous system vasculitis

,

spinocerebellar degenerations

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

lambert-eaton myasthenic syndrome

,

opsoclonus-myoclonus syndrome

,

oligodendroglioma

,

,

blastic plasmacytoid dendritic cell neoplasm

,

postural orthostatic tachycardia syndrome

,

orthostatic intolerance

,

sinus tachycardia

,

plasmablastic lymphoma

,

large-cell lymphoma immunoblastic

,

,

,

hemoglobinopathies

,

bone marrow failure disorders

,

wiskott-aldrich syndrome

,

hemophagocytic lymphohistiocytosis

,

diamond-blackfan anemia

,

shwachman-diamond syndrome

,

dyskeratosis congenita

,

inborn errors metabolism

,

pleural solitary fibrous tumor

,

esophageal squamous cell carcinoma

,

cutaneous malignant melanoma

,

,

mucopolysaccharidoses

,

sudden infant death

,

mucopolysaccharidosis ii

,

lysosomal storage diseases

,

non-alcoholic fatty liver disease

,

,

multiple pulmonary nodules

,

smoking cessation

,

bacterial infections

,

cerebrovascular disorders

,

b-cell lymphoma marginal zone

,

fontan procedure

,

,

bacterial vaginosis

,

vaginal diseases

,

trichomonas infections

,

cocaine-related disorders

,

cocaine smoking

,

,

,

lupus nephritis

,

,

second primary neoplasms

,

chemoradiotherapy

,

,

graft vs host disease

,

adjuvant chemoradiotherapy

,

intensity-modulated radiotherapy

,

papillomavirus infections

,

,

agammaglobulinemia

,

west nile virus

,

systemic scleroderma

,

juvenile arthritis

,

dermatomyositis

,

systemic lupus erythematosus

,

,

olfaction disorders

,

bile duct neoplasms

,

infectious arthritis

,

meningeal neoplasms

,

schistosomiasis haematobia

,

male breast neoplasms

,

urogenital neoplasms

,

male genital neoplasms

,

neuroendocrine tumors

,

islet cell adenoma

,

testicular neoplasms

,

,

periodontal pocket

,

cognitive remediation

,

health education

,

,

tendon injuries

,

,

respiratory syncytial virus infections

,

b-cell chronic lymphocytic leukemia

,

prolymphocytic leukemia

,

b-cell leukemia

,

acute-on-chronic liver failure

,

alcoholic hepatitis

,

cerebral hemorrhage

,

neuroinflammatory diseases

,

cerebral infarction

,

,

,

,

,

conduction aphasia

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

non-small-cell lung carcinoma

,

stomach neoplasms

,

burkitt lymphoma

,

breast neoplasms

,

,

,

,

,

prostatic neoplasms

,

,

,

,

myeloid leukemia acute

,

lymphoid leukemia

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

malignant mesothelioma

,

coronavirus infections

,

hepatocellular carcinoma

,

hodgkin disease

,

squamous cell carcinoma of head and neck

,

,

neoplasm metastasis

,

,

,

squamous cell carcinoma

,

colonic neoplasms

,

,

iron deficiencies

,

philadelphia chromosome

,

esophageal neoplasms

,

central nervous system neoplasms

,

,

post-dural puncture headache

,

cognitive dysfunction

,

,

iron-deficiency anemia

,

mantle-cell lymphoma

,

urinary bladder neoplasms

,

liver cirrhosis

,

medulloblastoma

,

allergic rhinitis

,

charcot-marie-tooth disease

,

chronic obstructive pulmonary disease

,

cardiovascular diseases

,

,

wounds and injuries

,

,

squamous cell neoplasms

,

ganglioneuroblastoma

,

,

transitional cell carcinoma

,

pulmonary blastoma

,

,

female genital diseases

,

obstructive lung diseases

,

cystic fibrosis

,

,

cardio-renal syndrome

,

deficiency diseases

,

peripheral nervous system diseases

,

,

left ventricular dysfunction

,

,

,

,

autosomal dominant polycystic kidney

,

,

,

inflammatory bowel diseases

,

,

,

,

meniere disease

,

,

hairy cell leukemia

,

strongyloidiasis

,

urethral neoplasms

,

ureteral neoplasms

,

,

phenylketonurias

,

basosquamous carcinoma

,

organ transplantation

,

22q11 deletion syndrome

,

serous cystadenocarcinoma

,

multidrug-resistant tuberculosis

,

allergic rhinitis perennial

,

nerve compression syndromes

,

,

hereditary sensory and motor neuropathy

,

,

,

,

,

ventricular dysfunction

,

cerebrospinal fluid leak

,

,

segmental mastectomy

,

cardiopulmonary bypass

,

,

,

mucocutaneous leishmaniasis

,

pyloric stenosis

,

gastric outlet obstruction

,

cardiomyopathies

,

diabetic cardiomyopathies

,

,

,

noise-induced hearing loss

,

,

spinal cord injuries

,

,

streptococcal infections

,

polycystic kidney diseases

,

substance-related disorders

,

,

,

,

,

,

haemophilus infections

,

,

,

,

hereditary congenital and neonatal diseases and abnormalities

,

,

,

anterior wall myocardial infarction

,

carcinoma in situ

,

,

gastrointestinal hemorrhage

,

cumulative trauma disorders

,

,

endometrial neoplasms

,

burning mouth syndrome

,

,

,

,

intrahepatic cholestasis

,

hyperventilation

,

cytomegalovirus infections

,

anterior cruciate ligament injuries

,

neoadjuvant therapy

,

healthy volunteers/patients

,

,

cutaneous leishmaniasis

,

,

,

,

,

,

colorectal neoplasms

,

vitamin d deficiency

,

,

irritable bowel syndrome

,

postoperative pain

,

sickle cell anemia

,

kidney diseases

,

knee osteoarthritis

,

communicable diseases

,

hypersensitivity

,

myocardial ischemia

,

,

major depressive disorder

,

,

,

,

,

oropharyngeal neoplasms

,

chronic renal insufficiency

,

depressive disorder

,

intestinal obstruction

,

,

,

human influenza

,

insulin resistance

,

migraine disorders

,

psychotic disorders

,

,

,

atrial fibrillation

,

,

,

atherosclerosis

,

coronary disease

,

coronary artery disease

,

disease progression

,

metabolic syndrome

,

pathologic constriction

,

postoperative nausea and vomiting

,

,

,

,

kidney transplantation

,

,

premature birth

,

cardiac surgical procedures

,

,

local anesthesia

,

,

,

drug-related side effects and adverse reactions

,

,

,

,

dry eye syndromes

,

visceral leishmaniasis

,

,

,

rotavirus infections

,

,

clostridium infections

,

dentin sensitivity

,

,

psychological distress

,

,

coronary stenosis

,

postherpetic neuralgia

,

,

,

,

patient satisfaction

,

personal satisfaction

,

respiratory aspiration of gastric contents

,

parenteral nutrition

,

,

treatment-resistant depressive disorder

,

ocular hypertension

,

open-angle glaucoma

,

,

peptic ulcer hemorrhage

,

acquired immunodeficiency syndrome

,

helicobacter infections

,

congenital abnormalities

,

,

chronic kidney failure

,

dysthymic disorder

,

,

,

,

,

,

,

,

angina pectoris

,

,

cardiac arrhythmias

,

liver transplantation

,

,

,

pulmonary edema

,

cesarean section

,

,

dental pulp necrosis

,

dental pulp diseases

,

nephrolithiasis

,

,

,

,

,

anxiety disorders

,

,

,

pathologic dilatation

,

,

,

,

fetal growth retardation

,

post-traumatic stress disorders

,

,

intestinal diseases

,

,

thyroid diseases

,

food hypersensitivity

,

,

marijuana abuse

,

,

,

end stage liver disease

,

hyperparathyroidism

,

muscular atrophy

,

gastrointestinal diseases

,

stomatognathic diseases

,

,

hypertriglyceridemia

,

,

therapeutic abortion

,

,

,

,

,

,

pelvic organ prolapse

,

,

,

compulsive personality disorder

,

,

,

respiratory distress syndrome

,

newborn respiratory distress syndrome

,

,

,

female urogenital diseases

,

urogenital diseases

,

,

digestive system diseases

,

,

maxillary fractures

,

,

sensorineural hearing loss

,

ischemic stroke

,

intracranial arteriosclerosis

,

muscle spasticity

,

,

,

learning disabilities

,

,

wound infection

,

amphetamine-related disorders

,

relapsing-remitting multiple sclerosis

,

,

hemolytic anemia

,

,

,

acute-phase reaction

,

parathyroid diseases

,

secondary hyperparathyroidism

,

,

essential hypertension

,

breast diseases

,

fibrocystic breast disease

,

heart disease risk factors

,

endocrine system diseases

,

neurocognitive disorders

,

chronic periodontitis

,

thyroid neoplasms

,

diaphragmatic hernias congenital

,

diaphragmatic hernia

,

multiple system atrophy

,

lewy body disease

,

frontotemporal dementia

,

progressive supranuclear palsy

,

frontotemporal lobar degeneration

,

pick disease of the brain

,

primary progressive nonfluent aphasia

,

corticobasal degeneration

,

female infertility

,

cervical ripening

,

,

keratoconjunctivitis sicca

,

uterine diseases

,

uterine cervical diseases

,

,

postpartum depression

,

puerperal disorders

,

spinal stenosis

,

,

ambulatory surgical procedures

,

sjogren's syndrome

,

,

craniofacial abnormalities

,

appendiceal neoplasms

,

,

pseudomyxoma peritonei

,

,

,

multiple organ failure

,

,

,

acquired ear deformities

,

postoperative complications

,

,

percutaneous coronary intervention

,

coronary circulation

,

family relations

,

family conflict

,

,

,

,

,

cholecystolithiasis

,

immunosuppression therapy

,

,

postmenopausal osteoporosis

,

,

,

vascular stiffness

,

acute coronary syndrome

,

portal hypertension

,

nutrition disorders

,

congenital disorders of glycosylation

,

,

gastroenteritis

,

digestive signs and symptoms

,

low anterior resection syndrome

,

,

,

,

lactose intolerance

,

skin abnormalities

,

patellofemoral pain syndrome

,

critical illness

,

,

,

renal replacement therapy

,

,

child nutrition disorders

,

,

premature obstetric labor

,

atrial heart septal defects

,

heart septal defects

,

respiratory aspiration

,

assisted reproductive techniques

,

ultrasonography

,

acute lung injury

,

pulmonary heart disease

,

surgical wound infection

,

fertilization in vitro

,

,

intracranial aneurysm

,

,

severe acute malnutrition

,

,

psychological resilience

,

military psychology

,

food diet and nutrition

,

reperfusion injury

,

,

duodenal neoplasms

,

acinar cell carcinoma

,

pancreatic intraductal neoplasms

,

and serous mucinous cystic neoplasms

,

ampulla of vater cancer

,

transient ischemic attack

,

ulcerative colitis

,

hyperlipidemias

,

,

urinary tract infections

,

chronic bronchitis

,

gastroesophageal reflux

,

multiple chronic conditions

,

chronic hepatitis

,

musculoskeletal pain

,

,

transfusion reaction

,

,

,

lymphadenopathy

,

ventricular tachycardia

,

ventricular fibrillation

,

palliative care

,

corneal diseases

,

,

pharmacokinetics

,

dental implants

,

,

cardiometabolic risk factors

,

body composition

,

,

glycogen storage disease type ii

,

spinal muscular atrophy

,

inclusion body myositis

,

spinal muscular atrophies of childhood

,

somatoform disorders

,

dissociative disorders

,

accidental injuries

,

urologic diseases

,

emergence delirium

,

orthopedic procedures

,

,

wrist fractures

,

,

pediatric obesity

,

urinary incontinence

,

postoperative care

,

preoperative care

,

uterine prolapse

,

atrophic vaginitis

,

physiological sexual dysfunction

,

postpartum period

,

,

,

psychosocial functioning

,

hip osteoarthritis

,

gingival recession

,

inborn genetic diseases

,

borderline personality disorder

,

self-injurious behavior

,

,

personality disorders

,

sedentary behavior

,

maxillofacial injuries

,

,

,

,

bariatric surgery

,

,

single-tooth dental implants

,

maxillofacial abnormalities

,

orthognathic surgery

,

edentulous mouth

,

respiratory insufficiency

,

water intoxication

,

mechanical ventilators

,

intervertebral disc degeneration

,

,

vestibular diseases

,

pulmonary embolism

,

,

drug hypersensitivity

,

respiratory tract infections

,

altitude sickness

,

nervous system trauma

,

,

acceptance and commitment therapy

,

cognitive behavioral therapy

,

neuromuscular blockade

,

stroke rehabilitation

,

postural balance

,

,

spontaneous abortion

,

,

,

acupuncture therapy

,

acute kidney injury

,

deglutition disorders

,

,

neurodevelopmental disorders

,

metabolic brain diseases

,

oxidative stress

,

,

auditory perception

,

,

,

,

,

peri-implantitis

,

,

,

diffuse intrinsic pontine glioma

,

,

speech intelligibility

,

alcohol drinking

,

family characteristics

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

periodontal diseases

,

,

procedural pain

,

,

transjugular intrahepatic portasystemic shunt

,

,

dental anesthesia

,

,

neurosurgical procedures

,

psychological well-being

,

percutaneous nephrolithotomy

,

,

tooth extraction

,

non-hodgkin lymphoma

,

ulcerative colitis

,

,

,

,

,

rheumatoid arthritis

,

,

pharmacokinetics

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

,

,

diffuse intrinsic pontine glioma

,

optic nerve glioma

,

brain stem neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

healthy volunteers/patients

,

,

peptic esophagitis

,

peripheral arterial disease

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mantle-cell lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

communicable diseases

,

,

,

gastroenteritis

,

,

non-erosive reflux disease

,

,

gastroesophageal reflux

,

sleep initiation and maintenance disorders

,

sleep wake disorders

,

,

atrial fibrillation

,

venous thromboembolism

,

thromboembolism

,

,

,

sudden death cardiac

,

,

Lisdexamfetamine

substance-related disorders

,

amphetamine-related disorders

,

,

attention deficit disorder with hyperactivity

Apadamtase alfa

sickle cell anemia

,

thrombocytopenic purpura

,

,

thrombotic thrombocytopenic purpura

healthy volunteers/patients

,

,

ulcerative colitis

,

,

,

b-cell lymphoma

,

inflammatory breast neoplasms

,

immunoglobulin light-chain amyloidosis

,

,

myeloproliferative disorders

,

primary myelofibrosis

,

promyelocytic leukemia acute

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia acute

,

myelomonocytic leukemia juvenile

,

,

systemic scleroderma

,

diffuse scleroderma

,

,

large b-cell lymphoma diffuse

,

,

myeloid leukemia acute

,

precursor cell lymphoblastic leukemia-lymphoma

,

non-hodgkin lymphoma

,

lymphoid leukemia

,

,

myeloid leukemia

,

myelodysplastic syndromes

,

multiple myeloma

,

plasma cell neoplasms

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

b-cell chronic lymphocytic leukemia

,

triple negative breast neoplasms

,

refractory anemia with excess of blasts

,

renal insufficiency

,

hematologic diseases

,

blood protein disorders

,

neoplasms by histologic type

,

paraproteinemias

,

hodgkin disease

,

diabetes mellitus

,

type 1 diabetes mellitus

,

prolymphocytic leukemia t-cell

,

prolymphocytic leukemia

,

,

burkitt lymphoma

,

graft vs host disease

,

bronchiolitis obliterans syndrome

,

aplastic anemia

,

breast neoplasms

,

brain stem neoplasms

,

glycogen storage disease type ii

,

glycogen storage disease type iii

,

ovarian neoplasms

,

hematologic neoplasms

1

2

3

4

5

6

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