Furazolidone
Furoxone (furazolidone) is a small molecule pharmaceutical. Furazolidone was first approved as Furoxone on 1982-01-01. It is used to treat animal salmonella infections, bacillary dysentery, cholera, diarrhea, and enteritis amongst others in the USA.
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ATC Codes
G: Genito urinary system and sex hormones
— G01: Gynecological antiinfectives and antiseptics
— G01A: Antiinfectives and antiseptics, excl. combinations with corticosteroids
— G01AX: Other gynecological antiinfectives and antiseptics in atc
— G01AX06: Furazolidone
P: Antiparasitic products, insecticides and repellents
— P01: Antiprotozoals
— P01A: Agents against amoebiasis and other protozoal diseases
— P01AB: Nitroimidazole derivatives, antiprotozoal agents against amoebiasis and other protozoal diseases
— P01AB51: Metronidazole and furazolidone
HCPCS
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Clinical
Clinical Trials
44 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | 1 | 2 | 1 | 15 | 11 | 29 |
| Helicobacter infections | D016481 | EFO_1000961 | — | 1 | 1 | 1 | 9 | 6 | 17 |
| Gastritis | D005756 | EFO_0000217 | K29.7 | — | — | — | 6 | 3 | 9 |
| Communicable diseases | D003141 | — | — | — | — | — | 5 | 4 | 9 |
| Disease susceptibility | D004198 | — | — | — | — | — | 6 | — | 6 |
| Peptic ulcer | D010437 | HP_0004398 | K27 | — | — | — | 3 | 1 | 4 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | — | — | 3 | — | 3 |
| Dyspepsia | D004415 | EFO_0008533 | K30 | — | — | — | 3 | — | 3 |
| Ulcer | D014456 | MPATH_579 | — | — | — | — | 1 | 1 | 2 |
| Stomach ulcer | D013276 | — | K25 | — | — | — | 1 | 1 | 2 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Thrombocytopenic purpura idiopathic | D016553 | EFO_0007160 | D69.3 | — | 1 | 1 | — | — | 1 |
| Thrombocytopenic purpura | D011696 | — | — | — | 1 | 1 | — | — | 1 |
| Purpura | D011693 | HP_0000979 | D69.2 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chinese traditional medicine | D008516 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Respiratory tract infections | D012141 | — | J06.9 | — | — | — | — | 1 | 1 |
| Malaria | D008288 | EFO_0001068 | B54 | — | — | — | — | 1 | 1 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | — | — | — | 1 | 1 |
| Neonatal sepsis | D000071074 | HP_0040187 | — | — | — | — | — | 1 | 1 |
| Diarrhea | D003967 | HP_0002014 | R19.7 | — | — | — | — | 1 | 1 |
| Asphyxia | D001237 | — | R09.01 | — | — | — | — | 1 | 1 |
| Asphyxia neonatorum | D001238 | EFO_1000824 | P84 | — | — | — | — | 1 | 1 |
| Microbiota | D064307 | — | — | — | — | — | — | 1 | 1 |
| Healthy volunteers/patients | — | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Furazolidone |
| INN | furazolidone |
| Description | Furazolidone is a nitrofuran antibacterial agent and monoamine oxidase inhibitor (MAOI). It is marketed by Roberts Laboratories under the brand name Furoxone and by GlaxoSmithKline as Dependal-M.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C1OCCN1/N=C/c1ccc([N+](=O)[O-])o1 |
Identifiers
| PDB | — |
| CAS-ID | 67-45-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1103 |
| ChEBI ID | — |
| PubChem CID | 3435 |
| DrugBank | DB00614 |
| UNII ID | 5J9CPU3RE0 (ChemIDplus, GSRS) |
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Furazolidone
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Safety
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219 adverse events reported
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