Moricizine
Ethmozine (moricizine) is a small molecule pharmaceutical. Moricizine was first approved as Ethmozine on 1990-06-19. It is used to treat cardiac arrhythmias, ventricular fibrillation, and ventricular tachycardia in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| cardiovascular diseases | D002318 |
| signs and symptoms pathological conditions | D013568 |
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Indications
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EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| ventricular tachycardia | — | D017180 | I47.2 |
| cardiac arrhythmias | EFO_0004269 | D001145 | I49.9 |
| ventricular fibrillation | HP_0001663 | D014693 | I49.01 |
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Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cardiovascular diseases | D002318 | HP_0001626 | — | — | 1 | 2 | — | — | 3 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 1 | 2 | — | — | 3 |
| Cardiac arrhythmias | D001145 | EFO_0004269 | I49.9 | — | 1 | 2 | — | — | 3 |
| Ventricular tachycardia | D017180 | — | I47.2 | — | 1 | 1 | — | — | 2 |
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | — | 1 | — | — | 1 |
| Myocardial infarction | D009203 | EFO_0000612 | I21 | — | — | 1 | — | — | 1 |
| Coronary disease | D003327 | — | — | — | — | 1 | — | — | 1 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | 1 | — | — | 1 |
| Sudden death cardiac | D016757 | EFO_0004278 | — | — | — | 1 | — | — | 1 |
| Heart arrest | D006323 | EFO_0009492 | I46 | — | — | 1 | — | — | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Moricizine |
| INN | moracizine |
| Description | Moricizine is a phenothiazine substituted on the nitrogen by a 3-(morpholin-4-yl)propanoyl group, and at position 2 by an (ethoxycarbonyl)amino group. It has a role as an anti-arrhythmia drug. It is a member of phenothiazines, a member of morpholines and a carbamate ester. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCOC(=O)Nc1ccc2c(c1)N(C(=O)CCN1CCOCC1)c1ccccc1S2 |
Identifiers
| PDB | — |
| CAS-ID | 31883-05-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1075 |
| ChEBI ID | 6997 |
| PubChem CID | 34633 |
| DrugBank | DB00680 |
| UNII ID | 2GT1D0TMX1 (ChemIDplus, GSRS) |
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