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Drug ReportsMoricizine
Moricizine
Ethmozine (moricizine) is a small molecule pharmaceutical. Moricizine was first approved as Ethmozine on 1990-06-19. It is used to treat cardiac arrhythmias, ventricular fibrillation, and ventricular tachycardia in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
cardiovascular diseasesD002318
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Moricizine hydrochloride
Tradename
Company
Number
Date
Products
ETHMOZINEShireN-019753 DISCN1990-06-19
3 products
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Labels
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
C: Cardiovascular system drugs
— C01: Cardiac therapy drugs
— C01B: Antiarrhythmics, class i and iii
— C01BG: Other antiarrhythmics, class i and iii in atc
— C01BG01: Moracizine
HCPCS
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Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cardiovascular diseasesD002318HP_0001626——12——3
Heart diseasesD006331EFO_0003777I51.9—12——3
Cardiac arrhythmiasD001145EFO_0004269I49.9—12——3
Ventricular tachycardiaD017180—I47.2—11——2
Atrial fibrillationD001281EFO_0000275I48.0——1——1
Myocardial infarctionD009203EFO_0000612I21——1——1
Coronary diseaseD003327————1——1
Myocardial ischemiaD017202EFO_1001375I20-I25——1——1
Sudden death cardiacD016757EFO_0004278———1——1
Heart arrestD006323EFO_0009492I46——1——1
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMoricizine
INNmoracizine
Description
Moricizine is a phenothiazine substituted on the nitrogen by a 3-(morpholin-4-yl)propanoyl group, and at position 2 by an (ethoxycarbonyl)amino group. It has a role as an anti-arrhythmia drug. It is a member of phenothiazines, a member of morpholines and a carbamate ester.
Classification
Small molecule
Drug class—
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Structure (InChI/SMILES or Protein Sequence)
CCOC(=O)Nc1ccc2c(c1)N(C(=O)CCN1CCOCC1)c1ccccc1S2
Identifiers
PDB—
CAS-ID31883-05-3
RxCUI—
ChEMBL IDCHEMBL1075
ChEBI ID6997
PubChem CID34633
DrugBankDB00680
UNII ID2GT1D0TMX1 (ChemIDplus, GSRS)
Target
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Variants
No data
Financial
No data
Trends
PubMed Central
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Safety
Black-box Warning
No Black-box warning
Adverse Events
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5 adverse events reported
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