Tradename | Company | Number | Date | Products |
---|---|---|---|---|
DIUPRES-250 | Merck KGaA | N-011635 DISCN | 1987-08-26 | 1 products |
DIUPRES-500 | Merck KGaA | N-011635 DISCN | 1987-08-26 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
HYDROPRES 25 | Merck KGaA | N-011958 DISCN | 1982-01-01 | 1 products |
HYDROPRES 50 | Merck KGaA | N-011958 DISCN | 1982-01-01 | 1 products |
SERPASIL-ESIDRIX #1 | Novartis | N-011878 DISCN | 1982-01-01 | 1 products |
SERPASIL-ESIDRIX #2 | Novartis | N-011878 DISCN | 1982-01-01 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
DIUTENSEN-R | Medpointe Pharm Hlc | N-012708 DISCN | 1982-01-01 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
HYDROMOX R | Lederle Laboratories | N-013927 DISCN | 1982-01-01 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
HISERPIA | Bowman Pharmaceuticals | N-009631 DISCN | 1982-01-01 | 2 products |
RAU-SED | Bristol Myers Squibb | N-009357 DISCN | 1982-01-01 | 4 products |
RESERPINE | CM Bundy | N-009663 DISCN | 1982-01-01 | 2 products |
RESERPINE | Cycle Pharmaceuticals | N-009859 DISCN | 1982-01-01 | 2 products |
RESERPINE | EveryLife Foundation for Rare Diseases | N-010441 DISCN | 1982-01-01 | 4 products |
RESERPINE | Impax Laboratories | N-009627 DISCN | 1982-01-01 | 2 products |
RESERPINE | Teva | N-011185 DISCN | 1982-01-01 | 2 products |
SERPALAN | Lannett | N-010124 DISCN | 1982-01-01 | 2 products |
SANDRIL | Eli Lilly | N-009376 DISCN | 1982-01-01 | 2 products |
SANDRIL | Eli Lilly | N-010012 DISCN | 1982-01-01 | 1 products |
SERPASIL | Novartis | N-009115 DISCN | 1982-01-01 | 4 products |
SERPASIL | Novartis | N-009434 DISCN | 1982-01-01 | 1 products |
SERPANRAY | Panray Corporation | N-009391 DISCN | 1982-01-01 | 3 products |
RESERPINE | Sandoz | N-009838 DISCN | 1982-01-01 | 2 products, RLD |
SERPATE | Bausch Health Companies | N-009453 DISCN | 1982-01-01 | 2 products |
RESERPINE | Bausch Health Companies | N-009667 DISCN | 1982-01-01 | 2 products |
SERPIVITE | Vitarine Pharmaceuticals | N-009645 DISCN | 1982-01-01 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
NAQUA | Merck & Co | N-012265 DISCN | 1982-01-01 | 2 products |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
dyskinesias | HP_0002310 | D020820 | G24 |
hypertension | EFO_0000537 | D006973 | I10 |
schizophrenia | EFO_0000692 | D012559 | F20 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hypertension | D006973 | EFO_0000537 | I10 | 1 | 2 | 3 | 1 | 3 | 10 |
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | 1 | 1 | 3 | 5 |
Postoperative pain | D010149 | — | G89.18 | — | 3 | 2 | 2 | — | 5 |
Chronic renal insufficiency | D051436 | — | N18 | — | — | — | 1 | 2 | 3 |
Neuromuscular blockade | D019148 | — | — | — | — | — | 1 | 1 | 2 |
Coronary artery disease | D003324 | — | I25.1 | — | — | — | 1 | 1 | 2 |
Vitamin d deficiency | D014808 | EFO_0003762 | E55 | — | — | — | 1 | — | 1 |
Postoperative complications | D011183 | — | — | — | — | — | 1 | — | 1 |
Postoperative nausea and vomiting | D020250 | EFO_0004888 | — | — | — | — | 1 | — | 1 |
Hoarseness | D006685 | HP_0001609 | R49.0 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cardiovascular diseases | D002318 | HP_0001626 | — | — | 1 | 2 | — | 1 | 4 |
Hypercholesterolemia | D006937 | HP_0003124 | — | — | — | 1 | — | 2 | 3 |
Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | — | 1 | — | 1 | 2 |
Overactive urinary bladder | D053201 | EFO_1000781 | N32.81 | — | — | 2 | — | — | 2 |
Ectopic pregnancy | D011271 | — | O00 | 1 | 1 | 1 | — | — | 2 |
Major depressive disorder | D003865 | EFO_0003761 | F22 | — | — | 1 | — | 1 | 2 |
Heart diseases | D006331 | EFO_0003777 | I51.9 | — | 1 | 1 | — | — | 2 |
Coronary disease | D003327 | — | — | — | — | 1 | — | — | 1 |
Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | — | 1 | — | — | 1 |
Conscious sedation | D016292 | — | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Myelodysplastic syndromes | D009190 | — | D46 | — | 2 | — | — | — | 2 |
Myeloid leukemia acute | D015470 | — | C92.0 | — | 2 | — | — | — | 2 |
Non-hodgkin lymphoma | D008228 | — | C85.9 | — | 2 | — | — | — | 2 |
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | — | 2 | — | — | — | 2 |
B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | — | 2 | — | — | — | 2 |
Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | — | 2 | — | — | — | 2 |
Digeorge syndrome | D004062 | — | D82.1 | 1 | 1 | — | — | 1 | 2 |
Hypersensitivity | D006967 | HP_0012393 | T78.40 | — | 1 | — | — | 1 | 2 |
Cocaine-related disorders | D019970 | — | F14 | — | 2 | — | — | — | 2 |
Pheochromocytoma | D010673 | — | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Prostatic neoplasms | D011471 | — | C61 | 1 | — | — | — | 2 | 3 |
Renal insufficiency | D051437 | HP_0000083 | N19 | 1 | — | — | — | 2 | 3 |
Colorectal neoplasms | D015179 | — | — | 1 | — | — | — | 2 | 3 |
Pulmonary arterial hypertension | D000081029 | — | — | 1 | — | — | — | 1 | 2 |
Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
Hemorrhage | D006470 | MP_0001914 | R58 | 1 | — | — | — | — | 1 |
Amphetamine-related disorders | D019969 | EFO_0004701 | F15 | 1 | — | — | — | — | 1 |
Respiratory distress syndrome | D012128 | EFO_1000637 | J80 | 1 | — | — | — | — | 1 |
Hypoxia | D000860 | HP_0012418 | R09.02 | 1 | — | — | — | — | 1 |
Drug interactions | D004347 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Covid-19 | D000086382 | — | U07.1 | — | — | — | — | 6 | 6 |
Anesthesia | D000758 | — | — | — | — | — | — | 3 | 3 |
Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 3 | 3 |
Uterine cervical neoplasms | D002583 | HP_0030159 | — | — | — | — | — | 2 | 2 |
Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | — | — | — | 2 | 2 |
Delirium | D003693 | — | R41.0 | — | — | — | — | 2 | 2 |
Down syndrome | D004314 | EFO_0001064 | Q90 | — | — | — | — | 2 | 2 |
Trisomy 18 syndrome | D000073842 | — | Q91.3 | — | — | — | — | 2 | 2 |
Trisomy 13 syndrome | D000073839 | — | Q91.7 | — | — | — | — | 2 | 2 |
Heart failure | D006333 | HP_0001635 | I50 | — | — | — | — | 2 | 2 |
Drug common name | Reserpine |
INN | reserpine |
Description | Reserpine is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. It has a role as an antihypertensive agent, a first generation antipsychotic, an adrenergic uptake inhibitor, an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor, an environmental contaminant, a xenobiotic and a plant metabolite. It is an alkaloid ester, a methyl ester and a yohimban alkaloid. It is functionally related to a reserpic acid. |
Classification | Small molecule |
Drug class | tricyclic compounds; Rauwolfia alkaloid derivatives |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5cc(OC)ccc5c4CCN3C[C@H]2C[C@@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)[C@@H]1OC |
PDB | — |
CAS-ID | 50-55-5 |
RxCUI | — |
ChEMBL ID | CHEMBL772 |
ChEBI ID | 28487 |
PubChem CID | 5770 |
DrugBank | DB00206 |
UNII ID | 8B1QWR724A (ChemIDplus, GSRS) |