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Company ReportsJazz Pharmaceuticals

Jazz Pharmaceuticals(JAZZ)

Jazz Pharmaceuticals plc (a merger of Jazz Pharmaceuticals, Inc. and Azur Pharma plc) is a biopharmaceutical company based in Ireland. It was founded in 2003. One of the company's considerable products is the United States Food and Drug Administration (FDA) approved drug Xyrem (sodium oxybate), the sodium salt of the naturally occurring neurotransmitter γ-Hydroxybutyric acid (GHB). In 2017, net product sales of Xyrem were $1.187 billion, which represented 74% of the company's total net product sales. In 2019, Jazz was granted FDA-approval to market Sunosi with indications for treating excessive daytime sleepiness (EDS) in narcolepsy as well as obstructive sleep apnea (OSA). In 2022, it was announced that Axsome Therapeutics would be acquiring Sunosi from Jazz Pharmaceuticals

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Marketed Drugs

Clinical Trials

Financial

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Company Revenue

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Projections

*Quarterly sales USD (in millions)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Defitelio	Defibrotide sodium	2016-03-30	2032	Hepatic veno-occlusive disease
Erwinaze	Asparaginase erwinia chrysanthemi	2011-11-18		—
Fazaclo	Clozapine	2004-02-10	2028	Schizophrenia , Psychotic disorders , Bipolar disorder , Schizophrenia spectrum and other psychotic disorders
Luvox	Fluvoxamine	2008-02-28		Panic disorder, Obsessive-compulsive disorder, Depressive disorder
Rylaze	Asparaginase erwinia chrysanthemi	2021-06-30		—
Vyxeos (previously vyxeos)	Cytarabine, Daunorubicin	2018-08-23	2025-2032	Leukemia, Myeloid leukemia acute, Lymphoma, Precursor cell lymphoblastic leukemia-lymphoma, Meningeal neoplasms
Xyrem	Oxybate	2002-07-17	2024-2042	Narcolepsy, Cataplexy
Xywav	Oxybate	2020-07-21	2024-2042	Narcolepsy, Cataplexy
Zepzelca	Lurbinectedin	2020-06-15	2029	Small cell lung carcinoma
Epidyolex	Cannabidiol	2019-09-19	2035-2041	Pain, Myoclonic epilepsies, Lennox gastaut syndrome, Anxiety
Enrylaze	Asparaginase erwinia chrysanthemi	2023-09-15		—
Epidiolex	Cannabidiol	2018-09-28	2035-2041	Pain, Myoclonic epilepsies, Lennox gastaut syndrome, Anxiety

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

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small cell carcinoma

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ovarian neoplasms

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ovarian epithelial carcinoma

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,

,

,

,

,

neuroendocrine carcinoma

,

gastrointestinal diseases

,

urologic neoplasms

,

transitional cell carcinoma

,

desmoplastic small round cell tumor

,

,

small cell lung carcinoma

healthy volunteers/patients

,

hepatic insufficiency

,

status epilepticus

,

,

,

opioid-related disorders

,

brain stem infarctions

,

sturge-weber syndrome

,

klippel-trenaunay-weber syndrome

,

diabetes mellitus

,

fragile x syndrome

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

,

brain neoplasms

,

,

heroin dependence

,

substance-related disorders

,

psychotic disorders

,

mental disorders

,

,

,

type 2 diabetes mellitus

,

,

ulcerative colitis

,

,

,

neuromyelitis optica

,

,

,

,

,

peripheral nervous system diseases

,

,

,

,

,

infantile spasms

,

spinal cord injuries

,

,

post-traumatic stress disorders

,

traumatic stress disorders

,

palliative care

,

postoperative nausea and vomiting

,

,

,

postoperative pain

,

,

overactive urinary bladder

,

diabetic neuropathies

,

,

,

multiple sclerosis

,

muscle spasticity

,

myoclonic epilepsies

,

lennox gastaut syndrome

,

,

tuberous sclerosis

,

absence epilepsy

,

drug resistant epilepsy

,

pregnancy complications

,

Defibrotide sodium

respiratory distress syndrome

,

severe acute respiratory syndrome-related coronavirus

,

acute lung injury

,

newborn respiratory distress syndrome

,

,

,

neurotoxicity syndromes

,

graft vs host disease

,

,

vascular diseases

,

thrombotic microangiopathies

,

hepatic veno-occlusive disease

t-cell lymphoma cutaneous

,

hypersensitivity

,

leukemia myeloid chronic atypical bcr-abl negative

,

neutrophilic leukemia chronic

,

colorectal neoplasms

,

stomach neoplasms

,

esophageal neoplasms

,

rectal neoplasms

,

neoplasms by histologic type

,

,

,

,

,

myeloid leukemia accelerated phase

,

primary myelofibrosis

,

aids-related lymphoma

,

nervous system neoplasms

,

prolymphocytic leukemia

,

,

b-cell lymphoma marginal zone

,

pathologic complete response

,

prolymphocytic leukemia t-cell

,

,

adult t-cell leukemia-lymphoma

,

peripheral blood stem cell transplantation

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

neurotoxicity syndromes

,

brain neoplasms

,

healthy volunteers/patients

,

,

pseudoxanthoma elasticum

,

,

hematologic diseases

,

,

medulloblastoma

,

plasma cell leukemia

,

aplastic anemia

,

immunoblastic lymphadenopathy

,

prolymphocytic leukemia b-cell

,

lymphoproliferative disorders

,

congenital abnormalities

,

,

behavior therapy

,

enteropathy-associated t-cell lymphoma

,

second primary neoplasms

,

phenylketonurias

,

,

essential thrombocythemia

,

polycythemia vera

,

,

,

,

hepatocellular carcinoma

,

vascular calcification

,

,

familial hypophosphatemic rickets

,

hypophosphatemic rickets

,

,

germ cell and embryonal neoplasms

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primitive neuroectodermal tumors

,

,

urologic neoplasms

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

,

clonal hematopoiesis

,

,

,

,

autoimmune diseases

,

nervous system diseases

,

autoimmune diseases of the nervous system

,

autologous transplantation

,

neuromyelitis optica

,

myasthenia gravis

,

ocular motility disorders

,

polyneuropathies

,

muscle weakness

,

,

stiff-person syndrome

,

central nervous system vasculitis

,

spinocerebellar degenerations

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

lambert-eaton myasthenic syndrome

,

opsoclonus-myoclonus syndrome

,

,

prostatic neoplasms

,

,

hiv seropositivity

,

intestinal neoplasms

,

radiation effects

,

,

,

,

hemophagocytic lymphohistiocytosis

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

liver neoplasms

,

systemic lupus erythematosus

,

leukoencephalopathies

,

progressive multifocal leukoencephalopathy

,

respiratory aspiration

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

intestinal diseases

,

stem cell transplantation

,

,

promyelocytic leukemia acute

,

,

,

chronic kidney failure

,

sickle cell anemia

,

hemoglobin sc disease

,

hemoglobin c disease

,

paroxysmal hemoglobinuria

,

,

,

extranodal nk-t-cell lymphoma

,

sezary syndrome

,

mycosis fungoides

,

hairy cell leukemia

,

intraocular lymphoma

,

large granular lymphocytic leukemia

,

lymphomatoid granulomatosis

,

,

,

ataxia telangiectasia

,

,

cerebellar ataxia

,

parkinson disease

,

parkinsonian disorders

,

hip osteoarthritis

,

knee osteoarthritis

,

,

electric stimulation therapy

,

precancerous conditions

,

,

chromosome aberrations

,

chromosome disorders

,

,

,

prediabetic state

,

diabetes mellitus

,

hypercholesterolemia

,

hyperhomocysteinemia

,

cognitive dysfunction

,

language development disorders

,

,

auditory perceptual disorders

,

,

beta-thalassemia

,

renal insufficiency

,

erectile dysfunction

,

,

,

eye abnormalities

,

gastrointestinal microbiome

,

spontaneous abortion

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

myeloid leukemia acute

,

myeloid leukemia

Asparaginase erwinia chrysanthemi

,

non-hodgkin lymphoma

,

hematologic neoplasms

,

,

philadelphia chromosome

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

hypersensitivity

Daunorubicin hydrochloride

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

myeloid leukemia acute

,

myeloid leukemia

breast neoplasms

,

drug interactions

breast neoplasms

,

peripheral arterial disease

,

,

,

,

gynecologic surgical procedures

,

,

pulmonary hypertension

,

renal insufficiency

,

,

t-cell lymphoma

,

immunoblastic lymphadenopathy

,

enteropathy-associated t-cell lymphoma

,

t-cell lymphoma peripheral

,

intestinal diseases

,

,

neuroendocrine tumors

,

carcinoid tumor

,

malignant carcinoid syndrome

,

carcinoid heart disease

,

serotonin syndrome

Fluorodopa f-18

type 2 diabetes mellitus

,

diabetes mellitus

,

healthy volunteers/patients

,

cardiomyopathies

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

type 1 diabetes mellitus

,

tobacco use disorder

,

hyperlipidemias

Samarium sm-153 lexidronam

prostatic neoplasms

,

breast neoplasms

,

neoplasm metastasis

biliary tract neoplasms

1

2

3

4

5

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