Cilmostim
Cilmostim is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Clinical Trials
731 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Myeloid leukemia acute | D015470 | — | C92.0 | 25 | 48 | 18 | 1 | 1 | 78 |
| Lymphoma | D008223 | — | C85.9 | 16 | 53 | 5 | 1 | 2 | 69 |
| Multiple myeloma | D009101 | — | C90.0 | 15 | 29 | 6 | 1 | 3 | 49 |
| Melanoma | D008545 | — | — | 21 | 25 | 4 | 1 | 3 | 46 |
| Neuroblastoma | D009447 | EFO_0000621 | — | 15 | 27 | 1 | 2 | 3 | 43 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 8 | 30 | 7 | 1 | 1 | 39 |
| Prostatic neoplasms | D011471 | — | C61 | 11 | 22 | 6 | 2 | — | 36 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 12 | 21 | 5 | 1 | — | 33 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 12 | 5 | 2 | 1 | 3 | 21 |
| Sepsis | D018805 | EFO_0001420 | A41.9 | 1 | 2 | 2 | 1 | 1 | 6 |
Show 8 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | 27 | 56 | 12 | — | 3 | 82 |
| Neoplasms | D009369 | — | C80 | 26 | 25 | 5 | — | 6 | 53 |
| Myelodysplastic syndromes | D009190 | — | D46 | 15 | 31 | 3 | — | 2 | 45 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 16 | 26 | 7 | — | — | 43 |
| Myeloid leukemia | D007951 | — | C92 | 11 | 16 | 5 | — | — | 27 |
| Plasma cell neoplasms | D054219 | — | — | 6 | 17 | 5 | — | 1 | 26 |
| Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | 8 | 18 | 1 | — | — | 23 |
| Hodgkin disease | D006689 | — | C81 | 7 | 14 | 2 | — | — | 20 |
| Glioblastoma | D005909 | EFO_0000515 | — | 11 | 12 | 1 | — | — | 19 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 4 | 14 | 3 | — | — | 19 |
Show 77 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 10 | 10 | — | — | — | 15 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 5 | 12 | — | — | — | 14 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 3 | 10 | — | — | — | 13 |
| Mantle-cell lymphoma | D020522 | — | C83.1 | 1 | 11 | — | — | — | 12 |
| Myeloproliferative disorders | D009196 | — | D47.1 | 1 | 9 | — | — | 1 | 11 |
| Fallopian tube neoplasms | D005185 | — | — | 4 | 7 | — | — | — | 10 |
| Glioma | D005910 | EFO_0000520 | — | 7 | 5 | — | — | — | 10 |
| Myelomonocytic leukemia chronic | D015477 | — | C93.1 | 7 | 3 | — | — | — | 9 |
| Syndrome | D013577 | — | — | 2 | 6 | — | — | 1 | 8 |
| Small cell lung carcinoma | D055752 | — | — | 4 | 6 | — | — | — | 8 |
Show 143 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancytopenia | D010198 | — | D61.81 | 4 | — | — | — | 2 | 6 |
| Cytopenia | D000095542 | — | — | 4 | — | — | — | 2 | 6 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | 1 | — | — | — | 2 | 3 |
| Virus diseases | D014777 | — | B34 | 2 | — | — | — | 1 | 3 |
| Leukopenia | D007970 | EFO_0004233 | D72.819 | 2 | — | — | — | 1 | 3 |
| Kaposi sarcoma | D012514 | — | C46 | 2 | — | — | — | — | 2 |
| Astrocytoma | D001254 | EFO_0000271 | — | 2 | — | — | — | — | 2 |
| Large-cell lymphoma anaplastic | D017728 | — | C84.6 | 2 | — | — | — | — | 2 |
| Clear cell sarcoma | D018227 | — | — | 2 | — | — | — | — | 2 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | 1 | 2 |
Show 37 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Abnormal karyotype | D059786 | — | — | — | — | — | — | 1 | 1 |
| Primitive neuroectodermal tumors | D018242 | — | — | — | — | — | — | 1 | 1 |
| Retinal neoplasms | D019572 | — | C69.2 | — | — | — | — | 1 | 1 |
| Neuroectodermal tumors | D017599 | — | — | — | — | — | — | 1 | 1 |
| Phenylketonurias | D010661 | — | E70.0 | — | — | — | — | 1 | 1 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | — | 1 | 1 |
| Uterine neoplasms | D014594 | EFO_0003859 | C55 | — | — | — | — | 1 | 1 |
| Carcinogenesis | D063646 | — | — | — | — | — | — | 1 | 1 |
| Cytokine release syndrome | D000080424 | — | D89.83 | — | — | — | — | 1 | 1 |
| Normal pressure hydrocephalus | D006850 | EFO_1001065 | G91.2 | — | — | — | — | 1 | 1 |
Show 14 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Cilmostim |
| INN | cilmostim |
| Description | Cilmostim is a protein pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Protein |
| Drug class | colony-stimulating factors: macrophage colony-stimulating factors (M-CSF) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108239 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | EWL6971ETP (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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253 adverse events reported
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