Cilmostim
Cilmostim is a protein pharmaceutical. It is currently being investigated in clinical studies.
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499 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Myeloid leukemia acute | D015470 | — | C92.0 | 12 | 21 | 10 | 1 | — | 38 |
| Lymphoma | D008223 | — | C85.9 | 5 | 32 | — | 1 | 2 | 38 |
| Melanoma | D008545 | — | — | 11 | 16 | 3 | 1 | 2 | 30 |
| Prostatic neoplasms | D011471 | — | C61 | 8 | 17 | 4 | 2 | — | 28 |
| Neuroblastoma | D009447 | EFO_0000621 | — | 8 | 17 | 1 | 2 | 3 | 28 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 5 | 15 | 5 | 1 | — | 20 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 4 | 9 | 2 | 1 | — | 15 |
| Chronic hepatitis b | D019694 | EFO_0004239 | B18.1 | — | 1 | 1 | 1 | 1 | 4 |
| Retinoblastoma | D012175 | — | — | 2 | — | — | 1 | 1 | 4 |
| Hepatoblastoma | D018197 | — | C22.2 | 1 | — | — | 1 | 1 | 3 |
Show 2 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | 9 | 34 | 2 | — | 1 | 41 |
| Multiple myeloma | D009101 | — | C90.0 | 7 | 16 | 3 | — | 4 | 28 |
| Myelodysplastic syndromes | D009190 | — | D46 | 9 | 18 | 1 | — | 1 | 26 |
| Neoplasms | D009369 | — | C80 | 14 | 10 | 2 | — | — | 22 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 11 | 12 | 3 | — | — | 22 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 11 | 5 | 2 | — | 3 | 19 |
| Hodgkin disease | D006689 | — | C81 | 3 | 8 | 2 | — | — | 12 |
| Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | 4 | 8 | 1 | — | — | 11 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 6 | 5 | 1 | — | — | 10 |
| Sarcoma | D012509 | — | — | 3 | 2 | 2 | — | 1 | 7 |
Show 34 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 5 | 6 | — | — | — | 9 |
| Glioblastoma | D005909 | EFO_0000515 | — | 6 | 6 | — | — | — | 9 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 2 | 7 | — | — | — | 8 |
| Non-small-cell lung carcinoma | D002289 | — | — | 2 | 4 | — | — | 1 | 7 |
| Fallopian tube neoplasms | D005185 | — | — | 2 | 5 | — | — | — | 7 |
| Myelomonocytic leukemia chronic | D015477 | — | C93.1 | 5 | 2 | — | — | — | 6 |
| Plasma cell neoplasms | D054219 | — | — | 1 | 5 | — | — | — | 6 |
| Pulmonary alveolar proteinosis | D011649 | HP_0006517 | J84.01 | 1 | 5 | — | — | — | 6 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 2 | 4 | — | — | — | 5 |
| Kidney neoplasms | D007680 | EFO_0003865 | C64 | 2 | 4 | — | — | — | 5 |
Show 76 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Kaposi sarcoma | D012514 | — | C46 | 2 | — | — | — | — | 2 |
| Clear cell sarcoma | D018227 | — | — | 2 | — | — | — | — | 2 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | 1 | 2 |
| Biphenotypic leukemia acute | D015456 | — | C95.0 | 1 | — | — | — | — | 1 |
| Aids-related lymphoma | D016483 | EFO_1001365 | — | 1 | — | — | — | — | 1 |
| Primary myelofibrosis | D055728 | — | D47.4 | 1 | — | — | — | — | 1 |
| Eyelid diseases | D005141 | EFO_0009547 | H02.9 | 1 | — | — | — | — | 1 |
| Basal cell carcinoma | D002280 | — | — | 1 | — | — | — | — | 1 |
| Merkel cell carcinoma | D015266 | EFO_1001471 | C4A | 1 | — | — | — | — | 1 |
| Basal cell neoplasms | D018295 | — | — | 1 | — | — | — | — | 1 |
Show 11 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Plasma cell leukemia | D007952 | — | C90.1 | — | — | — | — | 1 | 1 |
| Primitive neuroectodermal tumors | D018242 | — | — | — | — | — | — | 1 | 1 |
| Retinal neoplasms | D019572 | — | C69.2 | — | — | — | — | 1 | 1 |
| Phenylketonurias | D010661 | — | E70.0 | — | — | — | — | 1 | 1 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | — | 1 | 1 |
| Uterine neoplasms | D014594 | EFO_0003859 | C55 | — | — | — | — | 1 | 1 |
| Cytokine release syndrome | D000080424 | — | D89.83 | — | — | — | — | 1 | 1 |
| Virus diseases | D014777 | — | B34 | — | — | — | — | 1 | 1 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Cilmostim |
| INN | cilmostim |
| Description | Cilmostim is a protein pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Protein |
| Drug class | colony-stimulating factors: macrophage colony-stimulating factors (M-CSF) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108239 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | EWL6971ETP (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
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Adverse Events
Top Adverse Reactions
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244 adverse events reported
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