Tradename | Company | Number | Date | Products |
---|---|---|---|---|
DEPOCYT | Pacira BioSciences | N-021041 DISCN | 1999-04-01 | 1 products, RLD |
CYTARABINE | Teva | N-016793 DISCN | 1982-01-01 | 4 products, RLD |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
VYXEOS | Jazz Pharmaceuticals | N-209401 RX | 2017-08-03 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
byun rak | unapproved drug other | 2019-03-21 |
cytarabine | ANDA | 2025-04-07 |
vyxeos | New Drug Application | 2025-07-01 |
Expiration | Code | ||
---|---|---|---|
CYTARABINE / DAUNORUBICIN, VYXEOS, CELATOR PHARMS | |||
2028-03-30 | ODE-350 | ||
2024-08-03 | ODE-287 | ||
2024-03-30 | NPP |
Patent | Expires | Flag | FDA Information |
---|---|---|---|
Cytarabine / Daunorubicin, Vyxeos, Celator Pharms | |||
10028912 | 2032-10-15 | DP | U-3149, U-3150 |
10166184 | 2032-10-15 | DP | U-3149 |
10835492 | 2032-10-15 | U-3150 | |
8092828 | 2029-04-01 | U-3147 | |
8022279 | 2027-09-14 | DP | U-3147 |
7850990 | 2027-01-23 | DP | U-3147 |
9271931 | 2027-01-23 | DP | |
8518437 | 2026-06-07 | DP | |
8431806 | 2025-04-22 | DP | U-3147 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Myeloid leukemia acute | D015470 | — | C92.0 | 11 | 14 | 3 | — | — | 24 |
Leukemia | D007938 | — | C95 | 9 | 11 | 2 | — | — | 20 |
Myeloid leukemia | D007951 | — | C92 | 9 | 9 | 3 | — | — | 18 |
Myelodysplastic syndromes | D009190 | — | D46 | 4 | 4 | 1 | — | — | 8 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | 2 | 5 | — | — | — | 6 |
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 2 | 3 | — | — | — | 5 |
Preleukemia | D011289 | — | — | 2 | 1 | — | — | — | 3 |
Eyelid neoplasms | D005142 | EFO_1000934 | — | — | 3 | — | — | — | 3 |
Hematologic neoplasms | D019337 | — | — | 2 | 1 | — | — | — | 3 |
Neoplasm metastasis | D009362 | EFO_0009708 | — | — | 1 | — | — | 1 | 2 |
Lymphoid leukemia | D007945 | — | C91 | — | 2 | — | — | — | 2 |
Non-hodgkin lymphoma | D008228 | — | C85.9 | 1 | 1 | — | — | — | 2 |
Lymphoma | D008223 | — | C85.9 | 1 | 1 | — | — | — | 2 |
Myeloproliferative disorders | D009196 | — | D47.1 | 1 | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Syndrome | D013577 | — | — | 2 | — | — | — | — | 2 |
Hodgkin disease | D006689 | — | C81 | 1 | — | — | — | — | 1 |
Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 1 | — | — | — | — | 1 |
Large-cell lymphoma anaplastic | D017728 | — | C84.6 | 1 | — | — | — | — | 1 |
Burkitt lymphoma | D002051 | — | C83.7 | 1 | — | — | — | — | 1 |
Drug common name | Cytarabine |
INN | cytarabine |
Description | Cytarabine is a pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties. It has a role as an antineoplastic agent, an antimetabolite, an antiviral agent and an immunosuppressive agent. It is a beta-D-arabinoside, a pyrimidine nucleoside and a monosaccharide derivative. It is functionally related to a cytosine. |
Classification | Small molecule |
Drug class | antineoplastics (arabinofuranosyl derivatives) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1 |
PDB | — |
CAS-ID | 147-94-4 |
RxCUI | — |
ChEMBL ID | CHEMBL803 |
ChEBI ID | 28680 |
PubChem CID | 6253 |
DrugBank | DB00987 |
UNII ID | 04079A1RDZ (ChemIDplus, GSRS) |