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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Brukinsa	Zanubrutinib	2019-11-14	2034-2043	Mantle-cell lymphoma , Waldenstrom macroglobulinemia

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

colorectal neoplasms

,

pancreatic ductal carcinoma

,

,

non-small-cell lung carcinoma

,

stomach neoplasms

,

streptococcal infections

,

haemophilus infections

,

,

falciparum malaria

,

non-hodgkin lymphoma

,

,

b-cell lymphoma

,

hepatocellular carcinoma

,

liver neoplasms

,

esophageal squamous cell carcinoma

,

uterine cervical neoplasms

,

,

uveal neoplasms

,

,

,

non-small-cell lung carcinoma

,

squamous cell carcinoma

,

esophageal squamous cell carcinoma

,

uterine cervical neoplasms

,

small cell lung carcinoma

,

liver neoplasms

,

neoplasm metastasis

,

biliary tract neoplasms

,

cholangiocarcinoma

,

,

large b-cell lymphoma diffuse

,

triple negative breast neoplasms

,

non-small-cell lung carcinoma

,

,

ovarian neoplasms

head and neck neoplasms

,

squamous cell carcinoma of head and neck

healthy volunteers/patients

,

renal insufficiency

,

,

hepatic insufficiency

,

,

small cell lung carcinoma

,

,

colorectal neoplasms

,

,

,

cholangiocarcinoma

,

non-small-cell lung carcinoma

,

,

thyroid neoplasms

,

thyroid diseases

,

stomach neoplasms

,

ovarian neoplasms

,

chemoradiotherapy

,

head and neck neoplasms

,

breast neoplasms

,

pancreatic ductal carcinoma

,

hepatocellular carcinoma

,

ovarian epithelial carcinoma

,

anaplastic thyroid carcinoma

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

digestive system neoplasms

,

peritoneal neoplasms

,

,

,

rhabdomyosarcoma

,

male breast neoplasms

,

liver neoplasms

,

hematologic neoplasms

,

neoplasm metastasis

,

appendiceal neoplasms

,

triple negative breast neoplasms

,

,

mullerian mixed tumor

,

ampulla of vater cancer

,

bile duct neoplasms

,

ductal carcinoma

,

,

gallbladder neoplasms

,

islet cell adenoma

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

esophageal squamous cell carcinoma

,

,

pancreatic neoplasms

,

biliary tract neoplasms

,

rectal neoplasms

,

neuroendocrine tumors

,

neuroendocrine carcinoma

,

salivary gland neoplasms

Aglatimagene besadenovec

,

breast neoplasms

,

ovarian neoplasms

,

triple negative breast neoplasms

,

endometrial neoplasms

,

stomach neoplasms

,

urinary bladder neoplasms

,

small cell lung carcinoma

,

bites and stings

,

prostatic neoplasms

,

,

,

,

acquired immunodeficiency syndrome

,

,

cognitive dysfunction

ovarian neoplasms

antiphospholipid syndrome

,

female genital neoplasms

,

nervous system diseases

,

muscle weakness

,

adrenocortical carcinoma

,

,

muscular diseases

,

ductal carcinoma

,

juvenile arthritis

,

,

,

soft tissue neoplasms

,

gastrointestinal stromal tumors

,

bile duct neoplasms

,

pharmacokinetics

,

,

islet cell adenoma

,

deltaretrovirus infections

,

htlv-i infections

,

mycobacterium avium-intracellulare infection

,

optic nerve glioma

,

composite lymphoma

,

eyelid diseases

,

human influenza

,

osteogenesis imperfecta

,

neuroepithelial neoplasms

,

neurologic manifestations

,

mental disorders

,

,

pharyngeal neoplasms

,

,

camurati-engelmann syndrome

,

papillary thyroid cancer

,

medullary carcinoma

,

,

,

peripheral arterial disease

,

peripheral vascular diseases

,

carcinoid tumor

,

adrenal cortex neoplasms

,

papillomaviridae

,

,

x-linked ichthyosis

,

,

ovarian diseases

,

abdominal neoplasms

,

,

small cell carcinoma

,

neuromuscular manifestations

,

demyelinating diseases

,

cns demyelinating autoimmune diseases

,

transplantation tolerance

,

musculoskeletal diseases

,

rheumatic diseases

,

liver neoplasms

,

stomach neoplasms

,

hepatocellular carcinoma

,

prostatic neoplasms

,

,

,

head and neck neoplasms

,

esophageal neoplasms

,

prolymphocytic leukemia

,

,

t-cell lymphoma cutaneous

,

myeloid leukemia accelerated phase

,

,

squamous cell neoplasms

,

mycosis fungoides

,

adult t-cell leukemia-lymphoma

,

malignant mesothelioma

,

,

rheumatoid arthritis

,

myxoid liposarcoma

,

sezary syndrome

,

plasma cell leukemia

,

lymphomatoid granulomatosis

,

castration-resistant prostatic neoplasms

,

colonic neoplasms

,

precancerous conditions

,

,

aids-related lymphoma

,

chronic granulomatous disease

,

hairy cell leukemia

,

invasive hydatidiform mole

,

rectal neoplasms

,

thyroid neoplasms

,

,

,

,

cholangiocarcinoma

,

transitional cell carcinoma

,

prolymphocytic leukemia t-cell

,

autoimmune diseases of the nervous system

,

penile neoplasms

,

pancreatic ductal carcinoma

,

urologic neoplasms

,

merkel cell carcinoma

,

diffuse intrinsic pontine glioma

,

thymus neoplasms

,

blastic plasmacytoid dendritic cell neoplasm

,

intestinal neoplasms

,

neuroendocrine tumors

,

uveal neoplasms

,

,

intraocular lymphoma

,

metabolic diseases

,

polycythemia vera

,

kidney transplantation

,

second primary neoplasms

,

oropharyngeal neoplasms

,

large granular lymphocytic leukemia

,

serous cystadenocarcinoma

,

desmoplastic small round cell tumor

,

gastrointestinal neoplasms

,

immunosuppression therapy

,

,

primary immunodeficiency diseases

,

common variable immunodeficiency

,

,

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

primary effusion lymphoma

,

cytokine release syndrome

,

wiskott-aldrich syndrome

,

healthy volunteers/patients

,

adenocarcinoma of lung

,

,

essential thrombocythemia

,

hypertrophic pyloric stenosis

,

thyroid diseases

,

immunoproliferative disorders

,

hemolytic anemia autoimmune

,

,

vaginal neoplasms

,

vulvar neoplasms

,

neoplasms by histologic type

,

cord blood stem cell transplantation

,

immunoglobulin g4-related disease

,

graft rejection

,

leukemia myeloid chronic atypical bcr-abl negative

,

castleman disease

,

,

intestinal diseases

,

,

,

inflammatory bowel diseases

,

,

,

,

opportunistic infections

,

,

x-linked combined immunodeficiency diseases

,

vitamin d deficiency

,

urogenital neoplasms

,

epstein-barr virus infections

,

,

pure red-cell aplasia

,

hemolytic anemia

,

type 1 diabetes mellitus

,

oligodendroglioma

,

cell- and tissue-based therapy

,

adoptive immunotherapy

,

congenital abnormalities

,

microsatellite instability

,

carcinoma in situ

,

malignant pleural effusion

,

prolymphocytic leukemia b-cell

,

cardiovascular diseases

,

,

liver transplantation

,

metabolic syndrome

,

gata2 deficiency

,

autoimmune lymphoproliferative syndrome

,

,

epidermolysis bullosa

,

,

neuroendocrine carcinoma

,

mucopolysaccharidosis vi

,

mucopolysaccharidosis i

,

alpha-mannosidosis

,

mannosidase deficiency diseases

,

inborn genetic diseases

,

glandular and epithelial neoplasms

,

digestive system neoplasms

,

ureteral neoplasms

,

stiff-person syndrome

,

,

meningeal neoplasms

,

,

,

neutrophilic leukemia chronic

,

uterine neoplasms

,

endometrioid carcinoma

,

cystadenocarcinoma

,

breast carcinoma in situ

,

lobular carcinoma

,

embryonal carcinoma

,

homologous transplantation

,

smoldering multiple myeloma

,

,

treatment refusal

,

,

,

focal segmental glomerulosclerosis

,

metabolic brain diseases

,

gastroenteritis

,

,

,

hiv seropositivity

,

pulmonary hypertension

,

,

,

,

mucopolysaccharidosis vii

,

aspartylglucosaminuria

,

sphingolipidoses

,

adenosquamous carcinoma

,

endocrine gland neoplasms

,

urethral neoplasms

,

nijmegen breakage syndrome

,

,

polyneuropathies

,

pseudomyxoma peritonei

,

neurofibromatosis 1

,

neurofibromatoses

,

biliary tract neoplasms

,

alzheimer disease

,

polyradiculoneuropathy

,

papillomavirus infections

,

experimental melanoma

,

smooth muscle tumor

,

anaplastic thyroid carcinoma

,

mesenchymal stem cell transplantation

,

migraine disorders

,

,

,

bone marrow diseases

,

central nervous system vasculitis

,

monoclonal gammopathy of undetermined significance

,

,

bronchial neoplasms

,

clear cell adenocarcinoma

,

acinar cell carcinoma

,

lymphadenopathy

,

thoracic neoplasms

,

clonal hematopoiesis

,

,

autologous transplantation

,

cortical blindness

,

non-gestational choriocarcinoma

,

antineoplastic combined chemotherapy protocols

,

appendiceal neoplasms

,

paranasal sinus neoplasms

,

neoplasms by site

,

,

,

gene rearrangement

,

conjunctival neoplasms

,

mast-cell leukemia

,

,

supratentorial neoplasms

,

basal cell carcinoma

,

basal cell nevus syndrome

,

,

hypereosinophilic syndrome

,

eosinophilic leukemia acute

,

,

mucopolysaccharidosis ii

,

peroxisomal disorders

,

systemic mastocytosis

,

,

combination drug therapy

,

infratentorial neoplasms

,

hereditary breast and ovarian cancer syndrome

,

prosthesis failure

,

,

mucinous cystadenocarcinoma

,

,

,

chronic fatigue syndrome

,

,

encephalomyelitis

,

,

frontotemporal dementia

,

type b niemann-pick disease

,

primary progressive aphasia

,

,

adenocarcinoma in situ

,

experimental neoplasms

,

,

,

,

gastrointestinal diseases

,

,

,

radiation effects

,

,

orthopedic procedures

,

,

mesodermal mixed tumor

,

gallbladder neoplasms

,

oral lichen planus

,

unilateral breast neoplasms

,

vulvar diseases

,

cervical intraepithelial neoplasia

,

uterine cervical dysplasia

,

giant cell tumor of bone

,

giant cell tumors

,

squamous intraepithelial lesions

,

,

intractable pain

,

metabolic brain diseases inborn

,

vesiculobullous skin diseases

,

antibiotic prophylaxis

,

,

ischemic stroke

,

,

cerebral infarction

,

,

,

,

heterologous transplantation

,

,

eyelid neoplasms

,

,

blood protein disorders

,

respiratory aspiration

,

,

chromosome aberrations

,

chromosome disorders

,

spontaneous remission

,

,

,

,

sickle cell trait

,

li-fraumeni syndrome

,

,

disease attributes

,

epithelioid hemangioendothelioma

,

vascular neoplasms

,

disorders of sex development

,

adipose tissue neoplasms

,

granular cell tumor

,

endometrial stromal sarcoma

,

olfactory esthesioneuroblastoma

,

,

paraneoplastic syndromes

,

duodenal neoplasms

,

,

,

behavior therapy

,

bronchogenic carcinoma

,

myeloid leukemia acute

,

myeloid leukemia

,

,

hematologic neoplasms

,

,

ovarian neoplasms

,

bcr-abl positive chronic myelogenous leukemia

,

,

myeloproliferative disorders

,

,

,

non-small-cell lung carcinoma

,

neoplasm metastasis

,

pancreatic neoplasms

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell lymphoma marginal zone

,

central nervous system neoplasms

,

colorectal neoplasms

,

autoimmune diseases

,

ovarian epithelial carcinoma

,

,

biphenotypic leukemia acute

,

myelodysplastic-myeloproliferative diseases

,

renal cell carcinoma

,

,

myelomonocytic leukemia chronic

,

kidney neoplasms

,

primary myelofibrosis

,

fallopian tube neoplasms

,

nervous system neoplasms

,

brain neoplasms

,

,

sickle cell anemia

,

hematologic diseases

,

b-cell leukemia

,

uterine cervical neoplasms

,

,

large-cell lymphoma immunoblastic

,

squamous cell carcinoma

,

refractory anemia with excess of blasts

,

t-cell leukemia

,

inflammatory breast neoplasms

,

multiple sclerosis

,

squamous cell carcinoma of head and neck

,

,

,

synovial sarcoma

,

neuroectodermal tumors

,

residual neoplasm

,

small cell lung carcinoma

,

plasmablastic lymphoma

,

,

immunologic deficiency syndromes

,

membranous glomerulonephritis

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

extranodal nk-t-cell lymphoma

,

bone marrow failure disorders

,

immune system diseases

,

,

,

,

,

testicular neoplasms

,

,

fanconi syndrome

,

peritoneal neoplasms

,

primitive neuroectodermal tumors peripheral

,

,

,

drug-related side effects and adverse reactions

,

cerebrotendinous xanthomatosis

,

thrombocytopenia

,

cutaneous malignant melanoma

,

pathologic complete response

,

embryonal rhabdomyosarcoma

,

classical conditioning

,

refractory anemia

,

myelomonocytic leukemia acute

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

paroxysmal hemoglobinuria

,

endometrial neoplasms

,

alveolar rhabdomyosarcoma

,

,

myasthenia gravis

,

interdigitating dendritic cell sarcoma

,

stem cell transplantation

,

thrombocytopenic purpura idiopathic

,

disease progression

,

ductal carcinoma breast

,

hemoglobinopathies

,

reactive arthritis

,

,

localized scleroderma

,

bone marrow transplantation

,

benign fibrous histiocytoma

,

ganglioneuroblastoma

,

clear cell sarcoma

,

,

hemophagocytic lymphohistiocytosis

,

phenylketonurias

,

paraproteinemias

,

malignant fibrous histiocytoma

,

peripheral blood stem cell transplantation

,

relapsing-remitting multiple sclerosis

,

chronic kidney failure

,

mucinous adenocarcinoma

,

,

monocytic leukemia acute

,

,

,

neurofibrosarcoma

,

,

,

chemotherapy-induced febrile neutropenia

,

erythroblastic leukemia acute

,

,

hemangiosarcoma

,

langerhans-cell histiocytosis

,

,

alveolar soft part sarcoma

,

brain stem neoplasms

,

,

chronic progressive multiple sclerosis

,

neuromyelitis optica

,

megakaryoblastic leukemia acute

,

diamond-blackfan anemia

,

,

connective tissue diseases

,

pulmonary fibrosis

,

lymphatic diseases

,

,

,

nerve sheath neoplasms

,

,

febrile neutropenia

,

neurotoxicity syndromes

,

,

promyelocytic leukemia acute

,

,

takayasu arteritis

,

aortic arch syndromes

,

dyskeratosis congenita

,

severe combined immunodeficiency

,

chediak-higashi syndrome

,

,

nephrotic syndrome

,

peripheral nervous system diseases

,

thrombocytopenic purpura

,

,

mouth neoplasms

,

mesenchymal chondrosarcoma

,

dermatofibrosarcoma

,

behcet syndrome

,

choroid plexus neoplasms

,

endodermal sinus tumor

,

breast diseases

,

,

,

pheochromocytoma

,

inborn errors metabolism

,

,

mucopolysaccharidoses

,

,

globoid cell leukodystrophy

,

adrenoleukodystrophy

,

unknown primary neoplasms

,

cognitive dysfunction

,

shwachman-diamond syndrome

,

pulmonary blastoma

,

solitary fibrous tumors

,

anti-glomerular basement membrane disease

,

chemotherapy-related cognitive impairment

,

trophoblastic neoplasms

,

,

,

choriocarcinoma

,

,

plasma cell granuloma

,

,

ocular motility disorders

,

,

opsoclonus-myoclonus syndrome

,

retinal neoplasms

,

gestational trophoblastic disease

,

metachromatic leukodystrophy

,

idiopathic pulmonary fibrosis

,

eosinophilic granuloma

,

,

,

niemann-pick diseases

,

type a niemann-pick disease

,

,

type c niemann-pick disease

,

pick disease of the brain

,

whole-body irradiation

,

gaucher disease

,

hemangiopericytoma

,

circulating neoplastic cells

,

adolescent development

,

,

hematopoietic stem cell mobilization

,

postoperative complications

,

perivascular epithelioid cell neoplasms

,

mullerian mixed tumor

,

,

,

,

sensorineural hearing loss

,

lipoid nephrosis

,

adjuvant chemotherapy

,

benign mucous membrane pemphigoid

,

meningeal tuberculosis

,

,

,

,

inguinal hernia

,

mixed connective tissue disease

,

neuronal ceroid-lipofuscinoses

,

tay-sachs disease

,

sandhoff disease

,

gm1 gangliosidosis

,

,

acute kidney injury

,

,

,

condylomata acuminata

,

patient preference

,

,

,

positron-emission tomography

,

,

,

breast neoplasms

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

non-hodgkin lymphoma

,

multiple myeloma

,

,

b-cell lymphoma

,

large b-cell lymphoma diffuse

,

lymphoid leukemia

,

plasma cell neoplasms

,

myelodysplastic syndromes

,

b-cell chronic lymphocytic leukemia

,

hodgkin disease

,

,

follicular lymphoma

,

,

triple negative breast neoplasms

,

,

mantle-cell lymphoma

,

t-cell lymphoma

,

burkitt lymphoma

,

graft vs host disease

,

t-cell lymphoma peripheral

,

systemic lupus erythematosus

,

,

,

aplastic anemia

,

lupus nephritis

,

systemic scleroderma

,

hematopoietic stem cell transplantation

,

waldenstrom macroglobulinemia

,

germ cell and embryonal neoplasms

,

large-cell lymphoma anaplastic

,

myelomonocytic leukemia juvenile

,

rhabdomyosarcoma

,

,

diffuse scleroderma

,

medulloblastoma

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

myeloid leukemia chronic-phase

,

,

immunoblastic lymphadenopathy

,

kidney diseases

,

lymphoproliferative disorders

,

primitive neuroectodermal tumors

,

philadelphia chromosome

,

,

immunoglobulin light-chain amyloidosis

,

,

,

,

male breast neoplasms

,

,

renal insufficiency

,

,

,

granulomatosis with polyangiitis

,

urinary bladder neoplasms

,

acquired immunodeficiency syndrome

,

iga glomerulonephritis

,

enteropathy-associated t-cell lymphoma

,

neoadjuvant therapy

,

microscopic polyangiitis

,

interstitial lung diseases

,

glomerulonephritis

,

bronchiolitis obliterans syndrome

,

,

beta-thalassemia

,

,

sjogren's syndrome

,

,

churg-strauss syndrome

,

diabetes mellitus

,

systemic vasculitis

,

,

myeloid sarcoma

,

postoperative pain

,

metabolic bone diseases

,

dermatomyositis

,

postmenopausal osteoporosis

,

type 2 diabetes mellitus

,

communicable diseases

,

,

,

,

polyarteritis nodosa

,

,

,

,

human herpesvirus 8

,

mediastinal neoplasms

,

glycogen storage disease type ii

,

,

,

acute coronary syndrome

,

,

glycogen storage disease type iii

,

intravesical administration

,

,

non-muscle invasive bladder neoplasms

,

retroperitoneal fibrosis

,

,

,

,

,

bone resorption

,

knee osteoarthritis

,

,

hemoglobin sc disease

,

hyper-igm immunodeficiency syndrome

,

alopecia areata

,

,

,

,

,

cytomegalovirus infections

,

hemoglobin c disease

,

taste disorders

,

,

,

,

ataxia telangiectasia

,

,

cerebellar ataxia

,

hypoparathyroidism

,

,

defense mechanisms

,

,

,

agammaglobulinemia

,

type 1 hyper-igm immunodeficiency syndrome

,

leukocyte-adhesion deficiency syndrome

,

hereditary congenital and neonatal diseases and abnormalities

,

radius fractures

,

fracture healing

,

wrist fractures

,

bariatric surgery

,

,

,

,

osteoporotic fractures

,

multiple endocrine neoplasia type 1

,

hashimoto disease

,

giant cell arteritis

,

polymyalgia rheumatica

,

hypersensitivity

,

leukocytoclastic vasculitis cutaneous

,

chronic disease

,

cerebrovascular disorders

,

pituitary neoplasms

,

sex cord-gonadal stromal tumors

,

sertoli-leydig cell tumor

,

,

,

pituitary diseases

,

leydig cell tumor

,

focal nodular hyperplasia

,

,

,

autonomic nervous system diseases

,

primary dysautonomias

,

hypoventilation

,

,

,

,

anorexia nervosa

,

,

,

nerve compression syndromes

,

,

charcot-marie-tooth disease

,

hereditary sensory and motor neuropathy

,

,

primary graft dysfunction

,

,

,

,

anxiety disorders

,

,

,

neurodegenerative diseases

,

congenital bone marrow failure syndromes

,

undiagnosed diseases

,

respiratory syncytial virus infections

,

,

cardiomyopathies

,

eye abnormalities

,

uveomeningoencephalitic syndrome

,

tumor microenvironment

,

wounds and injuries

,

spinal cord injuries

,

echocardiography

,

hyperspectral imaging

,

primary ovarian insufficiency

,

femoral fractures

,

femoral neck fractures

,

,

muscle neoplasms

,

cystic fibrosis

,

laparoscopic cholecystectomy

,

,

female infertility

,

,

breast cancer lymphedema

,

,

follow-up studies

,

,

,

,

,

nociplastic pain

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