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Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Brukinsa	Zanubrutinib	2019-11-14	2034-2043	Mantle-cell lymphoma , Waldenstrom macroglobulinemia

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

overactive urinary bladder

,

diabetic neuropathies

,

,

,

,

pancreatic ductal carcinoma

,

malignant mesothelioma

,

ovarian epithelial carcinoma

,

streptococcal infections

,

haemophilus infections

,

,

falciparum malaria

,

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

b-cell lymphoma marginal zone

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

b-cell lymphoma

,

,

follicular lymphoma

,

,

biliary tract neoplasms

,

uterine cervical neoplasms

,

,

hepatocellular carcinoma

,

liver neoplasms

,

squamous cell carcinoma

,

esophageal squamous cell carcinoma

,

uterine cervical neoplasms

,

small cell lung carcinoma

,

liver neoplasms

,

biliary tract neoplasms

,

cholangiocarcinoma

,

,

large b-cell lymphoma diffuse

,

triple negative breast neoplasms

,

non-small-cell lung carcinoma

,

,

healthy volunteers/patients

,

renal insufficiency

,

,

hepatic insufficiency

,

,

small cell lung carcinoma

,

,

colorectal neoplasms

,

,

,

cholangiocarcinoma

,

non-small-cell lung carcinoma

,

,

thyroid neoplasms

,

thyroid diseases

,

stomach neoplasms

,

ovarian neoplasms

,

chemoradiotherapy

,

head and neck neoplasms

,

breast neoplasms

,

pancreatic ductal carcinoma

,

hepatocellular carcinoma

,

ovarian epithelial carcinoma

,

squamous cell carcinoma

,

anaplastic thyroid carcinoma

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

digestive system neoplasms

,

peritoneal neoplasms

,

,

,

rhabdomyosarcoma

,

male breast neoplasms

,

liver neoplasms

,

hematologic neoplasms

,

neoplasm metastasis

,

appendiceal neoplasms

,

triple negative breast neoplasms

,

,

mullerian mixed tumor

,

ampulla of vater cancer

,

bile duct neoplasms

,

ductal carcinoma

,

,

gallbladder neoplasms

,

islet cell adenoma

,

squamous cell carcinoma of head and neck

,

esophageal squamous cell carcinoma

,

,

pancreatic neoplasms

,

neuroendocrine tumors

,

biliary tract neoplasms

,

neuroendocrine carcinoma

,

salivary gland neoplasms

Aglatimagene besadenovec

,

male breast neoplasms

,

diabetes mellitus

,

positron emission tomography computed tomography

,

sedentary behavior

,

intestinal neoplasms

,

venous thromboembolism

,

,

pleural effusion

,

nasopharyngeal carcinoma

,

carcinoma in situ

,

medullary carcinoma

,

malignant pleural effusion

,

,

preoperative exercise

,

hyperparathyroidism

,

anaplastic thyroid carcinoma

,

,

invasive hydatidiform mole

,

drug interactions

,

,

,

inflammatory breast neoplasms

,

,

,

thymus neoplasms

,

myeloid leukemia

,

secondary hyperparathyroidism

,

,

,

primitive neuroectodermal tumors peripheral

,

lobular carcinoma

,

,

prolymphocytic leukemia t-cell

,

prolymphocytic leukemia

,

,

,

,

,

somatostatinoma

,

meningeal carcinomatosis

,

appendiceal neoplasms

,

myeloproliferative disorders

,

myelodysplastic-myeloproliferative diseases

,

multiple endocrine neoplasia type 1

,

adenoviridae infections

,

,

pancreas transplantation

,

graft pancreatitis

,

lymphoid leukemia

,

neoplasms by histologic type

,

acinar cell carcinoma

,

mucoepidermoid carcinoma

,

mucoepidermoid tumor

,

pathologic neovascularization

,

,

coxsackievirus infections

,

pharyngeal neoplasms

,

adenocarcinoma of lung

,

,

basal cell carcinoma

,

basal cell neoplasms

,

adjuvant radiotherapy

,

pharmacokinetics

,

pharmacological phenomena

,

local neoplasm recurrence

,

hyperlipidemias

,

emission-computed tomography single-photon

,

pancreatic neoplasms

,

kidney neoplasms

,

stomach neoplasms

,

colonic neoplasms

,

esophageal neoplasms

,

circulating neoplastic cells

,

,

rectal neoplasms

,

triple negative breast neoplasms

,

,

transitional cell carcinoma

,

thyroid neoplasms

,

brain neoplasms

,

,

neuroendocrine carcinoma

,

,

hereditary breast and ovarian cancer syndrome

,

,

,

small cell carcinoma

,

testicular neoplasms

,

,

,

,

,

cognitive dysfunction

,

cholangiocarcinoma

,

hematologic neoplasms

,

papillary thyroid cancer

,

,

non-hodgkin lymphoma

,

vulvar neoplasms

,

,

,

penile neoplasms

,

radiation injuries

,

thromboembolism

,

pancreatic ductal carcinoma

,

,

nasopharyngeal neoplasms

,

squamous cell neoplasms

,

adenoid cystic carcinoma

,

,

,

uterine neoplasms

,

urethral neoplasms

,

unknown primary neoplasms

,

central nervous system neoplasms

,

biliary tract neoplasms

,

,

tobacco use disorder

,

neoadjuvant therapy

,

myelodysplastic syndromes

,

,

cutaneous malignant melanoma

,

b-cell chronic lymphocytic leukemia

,

large b-cell lymphoma diffuse

,

parathyroid neoplasms

,

malignant mesothelioma

,

gallbladder neoplasms

,

,

atrial fibrillation

,

hodgkin disease

,

,

peripheral nervous system diseases

,

laryngeal neoplasms

,

hypopharyngeal neoplasms

,

follicular adenocarcinoma

,

digestive system neoplasms

,

mantle-cell lymphoma

,

mouth neoplasms

,

adrenocortical carcinoma

,

b-cell lymphoma

,

dna mismatch repair

,

,

,

,

,

,

ductal carcinoma

,

urological manifestations

,

myeloid leukemia acute

,

intraductal carcinoma noninfiltrating

,

bites and stings

,

,

nervous system neoplasms

,

thyroid diseases

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

oropharyngeal neoplasms

,

burkitt lymphoma

,

clear cell adenocarcinoma

,

adenomyoepithelioma

,

uveal neoplasms

,

,

dna repair-deficiency disorders

,

islet cell carcinoma

,

,

,

premature birth

,

glandular and epithelial neoplasms

,

,

,

,

smoldering multiple myeloma

,

paraproteinemias

,

monoclonal gammopathy of undetermined significance

,

bile duct neoplasms

,

residual neoplasm

,

esophageal squamous cell carcinoma

,

,

lymphadenopathy

,

,

microsatellite instability

,

endophthalmitis

,

lacrimal apparatus diseases

,

,

disease-free survival

,

,

hormone-dependent neoplasms

,

palliative care

,

inborn genetic diseases

,

,

pheochromocytoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

sezary syndrome

,

large-cell lymphoma anaplastic

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

large-cell lymphoma immunoblastic

,

tongue neoplasms

,

malignant fibrous histiocytoma

,

interdigitating dendritic cell sarcoma

,

abdominal neoplasms

,

myelomonocytic leukemia chronic

,

systemic mastocytosis

,

myelomonocytic leukemia juvenile

,

hypereosinophilic syndrome

,

,

dermatofibrosarcoma

,

t-cell lymphoma

,

,

,

neurotoxicity syndromes

,

vitamin d deficiency

,

stress fractures

,

adenocarcinoma in situ

,

genetic polymorphism

,

risk reduction behavior

,

,

traumatic stress disorders

,

,

,

,

,

,

hereditary sensory and autonomic neuropathies

,

solitary fibrous tumors

,

,

hemangiopericytoma

,

human influenza

,

liver transplantation

,

gastric outlet obstruction

,

combination drug therapy

,

,

adenomatous polyposis coli

,

craniopharyngioma

,

,

wnt signaling pathway

,

adenosquamous carcinoma

,

,

optical imaging

,

thrombocytopenia

,

,

,

,

,

ovarian neoplasms

,

renal cell carcinoma

,

head and neck neoplasms

,

liver neoplasms

,

uterine cervical neoplasms

,

,

endometrial neoplasms

,

small cell lung carcinoma

,

,

urologic neoplasms

,

ovarian epithelial carcinoma

,

,

squamous cell carcinoma of head and neck

,

physiological sexual dysfunction

,

,

healthy volunteers/patients

,

,

stress urinary incontinence

,

salivary gland neoplasms

,

radiation effects

,

magnetic resonance imaging

,

,

squamous cell carcinoma

,

insulin resistance

,

prostatic intraepithelial neoplasia

,

fallopian tube neoplasms

,

,

gastrointestinal neoplasms

,

female genital neoplasms

,

precancerous conditions

,

,

positron-emission tomography

,

vaginal neoplasms

,

olfactory esthesioneuroblastoma

,

urge urinary incontinence

,

pelvic neoplasms

,

,

metabolic bone diseases

,

,

gastrointestinal diseases

,

,

urination disorders

,

communicable diseases

,

,

,

,

postoperative complications

,

diagnostic imaging

,

,

germ cell and embryonal neoplasms

,

radiofrequency ablation

,

x-linked bulbo-spinal atrophy

,

venous thrombosis

,

premature ejaculation

,

,

bacterial infections

,

penile erection

,

,

type 2 diabetes mellitus

,

spinal cord compression

,

bone resorption

,

peritoneal neoplasms

,

,

alopecia areata

,

,

post-traumatic stress disorders

,

,

epidural analgesia

,

,

chronic disease

,

large cell carcinoma

,

androgen-insensitivity syndrome

,

critical illness

,

,

hepatic veno-occlusive disease

,

,

breakthrough pain

,

minimally invasive surgical procedures

,

thoracic surgical procedures

,

urinary catheterization

,

,

polycystic ovary syndrome

,

male infertility

,

hyperthyroidism

,

vision disorders

,

directly observed therapy

,

passive cutaneous anaphylaxis

,

prostatic neoplasms

,

prostatic hyperplasia

,

castration-resistant prostatic neoplasms

,

,

,

,

breast neoplasms

,

neoplasm metastasis

,

,

lower urinary tract symptoms

,

,

urinary bladder neoplasms

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

erectile dysfunction

,

urinary incontinence

,

,

hypersensitivity

,

,

prostatic diseases

,

,

,

,

urogenital neoplasms

,

,

hepatocellular carcinoma

,

urinary retention

,

transurethral resection of prostate

,

overactive urinary bladder

,

lymphatic metastasis

,

disease progression

,

,

multiple myeloma

,

,

male genital neoplasms

,

cardiovascular diseases

,

,

urinary bladder neck obstruction

,

,

bone marrow diseases

,

metabolic syndrome

,

urologic diseases

,

neuroendocrine tumors

,

second primary neoplasms

,

plasma cell neoplasms

,

,

,

male genital diseases

,

genital diseases

,

,

anxiety disorders

,

urinary tract infections

,

,

,

male urogenital diseases

,

urogenital diseases

,

,

postoperative pain

,

neoplasms by site

,

drug-related side effects and adverse reactions

,

,

underactive urinary bladder

,

,

,

myocardial ischemia

,

wounds and injuries

,

neurogenic urinary bladder

,

intraoperative complications

,

,

nephrolithiasis

,

renal insufficiency

,

,

,

peripheral nerve injuries

,

retinal diseases

,

ureteral obstruction

,

pneumoperitoneum

,

autonomic nervous system diseases

,

intravenous administration

,

,

pituitary neoplasms

,

pituitary acth hypersecretion

,

pituitary diseases

,

acth-secreting pituitary adenoma

,

dumping syndrome

,

,

,

airway obstruction

,

osteochondrodysplasias

,

,

,

,

choroid diseases

,

pupil disorders

,

hypoalphalipoproteinemias

,

blood coagulation disorders

,

hemostatic disorders

,

nerve regeneration

,

primary dysautonomias

,

,

genetic predisposition to disease

,

,

sleep initiation and maintenance disorders

,

,

ejaculatory dysfunction

,

spinal anesthesia

,

,

,

urethral obstruction

,

,

ureteral neoplasms

,

,

health behavior

,

,

multiparametric magnetic resonance imaging

,

patient satisfaction

,

,

coronary artery disease

,

ultrasonography

,

,

pelvic floor disorders

,

,

,

,

intestinal diseases

,

,

,

,

,

acute kidney injury

,

digital rectal examination

,

psychological distress

,

,

,

,

interstitial cystitis

,

,

,

,

trigeminal neuralgia

,

depressive disorder

,

,

,

disease susceptibility

,

coronary disease

,

cardiac arrhythmias

,

heart disease risk factors

,

,

resistance training

,

,

mullerian mixed tumor

,

body composition

,

,

psychological sexual dysfunctions

,

soft tissue neoplasms

,

fecal incontinence

,

decision support techniques

,

kidney diseases

,

,

papillomaviridae

,

muscular atrophy

,

psychological stress

,

,

,

,

erythema multiforme

,

therapeutic embolization

,

myocardial infarction

,

cross infection

,

,

,

,

local anesthesia

,

urinary bladder diseases

,

spinal cord injuries

,

,

,

,

exercise therapy

,

pulmonary embolism

,

hereditary nonpolyposis colorectal neoplasms

,

,

patient participation

,

patient preference

,

urinary calculi

,

high-intensity focused ultrasound ablation

,

metabolic diseases

,

margins of excision

,

,

,

postoperative hemorrhage

,

thoracic neoplasms

,

shared decision making

,

,

,

pain management

,

patient acceptance of health care

,

clostridium botulinum type a

,

disease resistance

,

surgical blood loss

,

pharmacogenomic testing

,

,

prostheses and implants

,

,

,

,

,

carcinoid tumor

,

inguinal hernia

,

,

,

chronic kidney disease-mineral and bone disorder

,

,

,

,

supraventricular tachycardia

,

stomatognathic diseases

,

endocrine system diseases

,

autoimmune diseases

,

neurocognitive disorders

,

intravenous anesthesia

,

,

intermittent fasting

,

paraneoplastic syndromes

,

neurodegenerative diseases

,

,

interdisciplinary communication

,

inflammatory bowel diseases

,

,

embolism and thrombosis

,

rectal diseases

,

,

body weight changes

,

,

chronic renal insufficiency

,

polycystic kidney diseases

,

,

systemic scleroderma

,

psoriatic arthritis

,

,

atopic dermatitis

,

,

ulcerative colitis

,

parkinson disease

,

ankylosing spondylitis

,

multiple sclerosis

,

,

chronic obstructive pulmonary disease

,

,

,

lupus nephritis

,

glucosephosphate dehydrogenase deficiency

,

sickle cell anemia

,

,

acquired immunodeficiency syndrome

,

,

cystic fibrosis

,

thrombocytopenic purpura idiopathic

,

,

,

duchenne muscular dystrophy

,

sjogren's syndrome

,

obstructive lung diseases

,

systemic lupus erythematosus

,

beta-thalassemia

,

,

,

hereditary hemorrhagic telangiectasia

,

spondylarthritis

,

sickle cell trait

,

,

,

,

polyneuropathies

,

thrombotic thrombocytopenic purpura

,

huntington disease

,

diffuse scleroderma

,

spinal muscular atrophy

,

,

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

thrombocytopenic purpura

,

,

,

facioscapulohumeral muscular dystrophy

,

muscular dystrophies

,

,

,

,

myotonic dystrophy

,

,

bipolar disorder

,

attention deficit disorder with hyperactivity

,

chronic kidney failure

,

orthostatic hypotension

,

diabetes insipidus

,

,

pudendal neuralgia

,

,

,

ocular hypertension

,

spinal cord neoplasms

,

,

pathologic constriction

,

urethral stricture

,

,

rectovaginal fistula

,

kidney transplantation

,

,

geriatric psychiatry

,

personal satisfaction

,

disease attributes

,

artificial intelligence

,

cross-sectional studies

,

hypercholesterolemia

,

ultrasonic therapy

,

,

,

solid-state lasers

,

,

spinal dysraphism

,

bladder exstrophy

,

urinary bladder calculi

,

,

,

neoplasm staging

,

alzheimer disease

,

epidemiologic studies

,

penile implantation

,

high-intensity focused ultrasound transrectal

,

innate immunity

,

,

somatoform disorders

,

lymphatic diseases

,

,

compartment syndromes

,

interventional ultrasonography

,

prospective studies

,

image-guided biopsy

,

,

genetic markers

,

robotic surgical procedures

,

psychology biofeedback

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

diagnostic techniques and procedures

,

,

uterine artery embolization

,

arteriovenous malformations

,

neoplasm micrometastasis

,

,

water intoxication

,

,

venous insufficiency

,

mitochondrial diseases

,

dilated cardiomyopathy

,

,

,

,

pleural neoplasms

,

pelvic organ prolapse

,

,

,

,

von hippel-lindau disease

,

hereditary neoplastic syndromes

,

opioid-related disorders

,

body temperature changes

,

,

,

catheter ablation

,

non-alcoholic fatty liver disease

,

vasovagal syncope

,

,

,

post-acute covid-19 syndrome

,

sleep wake disorders

,

ureteral calculi

,

adrenal rest tumor

,

ureterolithiasis

,

respiratory aspiration

,

artificial respiration

,

positive-pressure respiration

,

treatment adherence and compliance

,

physician-patient relations

,

,

transfusion reaction

,

,

,

carpal tunnel syndrome

,

immune system diseases

,

memory disorders

,

,

digestive system diseases

,

arterial occlusive diseases

,

,

traumatic brain injuries

,

,

,

rhabdomyosarcoma

,

spinal neoplasms

,

,

schistosoma haematobium

,

,

,

,

professional-patient relations

,

,

ablation techniques

,

,

genetic testing

,

vascular access devices

,

hiv seropositivity

,

,

image-guided radiotherapy

,

acupuncture therapy

,

,

pain measurement

,

oligodendroglioma

,

,

mental disorders

,

randomized controlled trials as topic

,

papillomavirus infections

,

tertiary lymphoid structures

,

genetic risk score

,

,

motor skills disorders

,

cardiometabolic risk factors

,

,

urologic surgical procedures

,

signs and symptoms

,

major depressive disorder

,

treatment outcome

,

alphapapillomavirus

,

uterine cervical dysplasia

,

,

nervous system diseases

,

epidural anesthesia

,

,

elective surgical procedures

,

financial stress

,

acupuncture analgesia

,

,

general anesthesia

,

,

,

obstructive sleep apnea

,

sleep apnea syndromes

myeloid leukemia acute

,

precursor cell lymphoblastic leukemia-lymphoma

,

biphenotypic leukemia acute

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

ovarian neoplasms

,

fallopian tube neoplasms

,

ovarian epithelial carcinoma

,

,

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

mullerian mixed tumor

,

breast neoplasms

,

triple negative breast neoplasms

,

stomach neoplasms

healthy volunteers/patients

,

colorectal neoplasms

,

chronic renal insufficiency

,

kidney diseases

,

sickle cell anemia

,

knee osteoarthritis

,

,

,

,

ovarian neoplasms

,

,

ovarian epithelial carcinoma

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

laryngeal neoplasms

,

opioid-related disorders

,

,

coronavirus infections

,

,

,

urinary bladder neoplasms

,

brain neoplasms

,

serous cystadenocarcinoma

,

,

neurofibromatosis 2

,

acoustic neuroma

,

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

,

cystic fibrosis

,

,

biliary tract neoplasms

,

,

invasive hydatidiform mole

,

non-muscle invasive bladder neoplasms

,

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

mantle-cell lymphoma

,

b-cell lymphoma

,

b-cell leukemia

,

diabetes mellitus

,

chronic obstructive pulmonary disease

,

,

,

obstructive lung diseases

,

non-small-cell lung carcinoma

,

,

pulmonary eosinophilia

,

,

,

,

endometrial neoplasms

,

borderline personality disorder

,

personality disorders

,

churg-strauss syndrome

,

eosinophilic granuloma

,

type 2 diabetes mellitus

,

breast neoplasms

,

,

,

,

endomyocardial fibrosis

,

postoperative pain

,

,

major depressive disorder

,

depressive disorder

sickle cell anemia

,

,

colonic neoplasms

,

,

systemic lupus erythematosus

,

colorectal neoplasms

,

agammaglobulinemia

,

primary immunodeficiency diseases

,

von willebrand diseases

,

alzheimer disease

,

graft vs host disease

,

thrombocytopenic purpura idiopathic

,

protein c deficiency

,

,

myeloid leukemia acute

,

non-hodgkin lymphoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

hodgkin disease

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mantle-cell lymphoma

,

myeloid leukemia chronic-phase

,

large b-cell lymphoma diffuse

,

myeloid leukemia accelerated phase

,

burkitt lymphoma

,

large-cell lymphoma immunoblastic

,

,

thrombotic thrombocytopenic purpura

,

chronic obstructive pulmonary disease

,

,

mucocutaneous lymph node syndrome

,

immunologic deficiency syndromes

,

,

alpha 1-antitrypsin deficiency

,

,

healthy volunteers/patients

1

2

3

4

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