Regramostim
Regramostim is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Clinical Trials
907 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | 29 | 66 | 12 | 2 | 4 | 102 |
| Melanoma | D008545 | — | — | 40 | 63 | 8 | 1 | 6 | 99 |
| Lymphoma | D008223 | — | C85.9 | 25 | 69 | 7 | 1 | 1 | 95 |
| Neuroblastoma | D009447 | EFO_0000621 | — | 17 | 37 | 5 | 3 | 3 | 59 |
| Multiple myeloma | D009101 | — | C90.0 | 20 | 33 | 6 | 1 | — | 54 |
| Plasma cell neoplasms | D054219 | — | — | 18 | 29 | 6 | 1 | — | 48 |
| Myeloid leukemia | D007951 | — | C92 | 14 | 27 | 7 | 1 | 1 | 47 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 11 | 20 | 6 | 2 | 2 | 39 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 16 | 7 | 2 | 1 | 4 | 27 |
| Lymphoid leukemia | D007945 | — | C91 | 7 | 20 | 1 | 1 | — | 25 |
Show 19 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 42 | 49 | 1 | — | 4 | 79 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 35 | 41 | 6 | — | — | 72 |
| Prostatic neoplasms | D011471 | — | C61 | 25 | 45 | 6 | — | 2 | 66 |
| Carcinoma | D002277 | — | C80.0 | 24 | 32 | 4 | — | 1 | 53 |
| Myelodysplastic syndromes | D009190 | — | D46 | 15 | 23 | 1 | — | 3 | 40 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 7 | 26 | 5 | — | — | 36 |
| Preleukemia | D011289 | — | — | 12 | 18 | 1 | — | 2 | 31 |
| Recurrence | D012008 | — | — | 16 | 15 | 4 | — | — | 31 |
| Glioblastoma | D005909 | EFO_0000515 | — | 15 | 17 | 2 | — | — | 30 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 12 | 18 | 3 | — | — | 29 |
Show 62 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 14 | 19 | — | — | 2 | 31 |
| Colorectal neoplasms | D015179 | — | — | 17 | 21 | — | — | — | 29 |
| Syndrome | D013577 | — | — | 10 | 14 | — | — | 2 | 24 |
| Ovarian epithelial carcinoma | D000077216 | — | — | 10 | 13 | — | — | — | 22 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 9 | 8 | — | — | — | 15 |
| Glioma | D005910 | EFO_0000520 | — | 9 | 7 | — | — | — | 14 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 9 | 9 | — | — | — | 14 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 4 | 11 | — | — | — | 13 |
| Myeloproliferative disorders | D009196 | — | D47.1 | 3 | 9 | — | — | 1 | 12 |
| Hodgkin disease | D006689 | — | C81 | 5 | 9 | — | — | — | 12 |
Show 164 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukopenia | D007970 | EFO_0004233 | D72.819 | 3 | — | — | — | 1 | 4 |
| Diffuse intrinsic pontine glioma | D000080443 | — | — | 3 | — | — | — | — | 3 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | 3 | — | — | — | — | 3 |
| Kaposi sarcoma | D012514 | — | C46 | 2 | — | — | — | — | 2 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | 1 | — | — | — | 1 | 2 |
| Blast crisis | D001752 | — | — | 1 | — | — | — | 1 | 2 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | 1 | — | — | — | 1 | 2 |
| Lymphopenia | D008231 | — | D72.810 | 1 | — | — | — | — | 1 |
| Connective tissue diseases | D003240 | EFO_1001986 | M35 | 1 | — | — | — | — | 1 |
| Immune system diseases | D007154 | — | D89.9 | 1 | — | — | — | — | 1 |
Show 45 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Peritonitis | D010538 | EFO_0008588 | K65 | — | — | — | — | 3 | 3 |
| Herpes simplex | D006561 | — | B00 | — | — | — | — | 1 | 1 |
| Intracytoplasmic sperm injections | D020554 | — | — | — | — | — | — | 1 | 1 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | — | 1 | 1 |
| Mars | D018535 | — | — | — | — | — | — | 1 | 1 |
| Mutagenesis | D016296 | — | — | — | — | — | — | 1 | 1 |
| Cytokine release syndrome | D000080424 | — | D89.83 | — | — | — | — | 1 | 1 |
| Olfaction disorders | D000857 | — | R43.0 | — | — | — | — | 1 | 1 |
| Sinusitis | D012852 | EFO_0007486 | J32 | — | — | — | — | 1 | 1 |
| Nasal polyps | D009298 | — | J33 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Regramostim |
| INN | regramostim |
| Description | Regramostim is a protein pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Protein |
| Drug class | colony-stimulating factors: granulocyte macrophage colony-stimulating factors (GM-CSF); colony-stimulating factors: macrophage colony-stimulating factors (M-CSF) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2107881 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | KR89Q40F01 (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
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Adverse Events
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236 adverse events reported
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