Regramostim
Regramostim is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Clinical Trials
1478 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Myeloid leukemia acute | D015470 | — | C92.0 | 40 | 63 | 18 | 2 | 7 | 113 |
| Lymphoma | D008223 | — | C85.9 | 28 | 68 | 9 | 2 | 5 | 100 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 38 | 50 | 11 | 5 | 4 | 98 |
| Melanoma | D008545 | — | — | 40 | 60 | 6 | 1 | 6 | 98 |
| Leukemia | D007938 | — | C95 | 25 | 59 | 9 | 1 | 7 | 90 |
| Multiple myeloma | D009101 | — | C90.0 | 26 | 42 | 8 | 1 | 8 | 76 |
| Neoplasms | D009369 | — | C80 | 40 | 39 | 6 | 1 | 4 | 76 |
| Prostatic neoplasms | D011471 | — | C61 | 26 | 45 | 7 | 2 | 3 | 71 |
| Neuroblastoma | D009447 | EFO_0000621 | — | 22 | 36 | 10 | 3 | 4 | 68 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 11 | 29 | 6 | 2 | 5 | 49 |
Show 26 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Myelodysplastic syndromes | D009190 | — | D46 | 32 | 54 | 8 | — | 6 | 85 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 18 | 12 | 2 | — | 7 | 36 |
| Sarcoma | D012509 | — | — | 12 | 15 | 8 | — | 1 | 33 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 13 | 19 | 3 | — | 2 | 32 |
| Hodgkin disease | D006689 | — | C81 | 7 | 18 | 3 | — | 1 | 28 |
| Glioblastoma | D005909 | EFO_0000515 | — | 13 | 14 | 1 | — | — | 24 |
| Non-small-cell lung carcinoma | D002289 | — | — | 9 | 13 | 2 | — | 2 | 24 |
| Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | 9 | 13 | 3 | — | 1 | 23 |
| Plasma cell neoplasms | D054219 | — | — | 9 | 16 | 1 | — | — | 22 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 7 | 10 | 1 | — | 2 | 18 |
Show 89 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 14 | 19 | — | — | 5 | 34 |
| Colorectal neoplasms | D015179 | — | — | 15 | 20 | — | — | 1 | 28 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | 8 | 13 | — | — | 3 | 23 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 8 | 8 | — | — | — | 15 |
| Mantle-cell lymphoma | D020522 | — | C83.1 | 3 | 11 | — | — | — | 12 |
| Fallopian tube neoplasms | D005185 | — | — | 4 | 5 | — | — | 2 | 11 |
| Healthy volunteers/patients | — | — | — | 7 | 1 | — | — | 2 | 10 |
| Pulmonary alveolar proteinosis | D011649 | HP_0006517 | J84.01 | 2 | 7 | — | — | 1 | 10 |
| Glioma | D005910 | EFO_0000520 | — | 6 | 4 | — | — | — | 9 |
| Germ cell and embryonal neoplasms | D009373 | — | — | 3 | 2 | — | — | 2 | 7 |
Show 150 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diffuse intrinsic pontine glioma | D000080443 | — | — | 3 | — | — | — | — | 3 |
| Oligodendroglioma | D009837 | EFO_0000631 | — | 3 | — | — | — | — | 3 |
| Coronary artery disease | D003324 | — | I25.1 | 1 | — | — | — | 1 | 2 |
| Primitive neuroectodermal tumors | D018242 | — | — | 1 | — | — | — | 1 | 2 |
| Clear cell sarcoma | D018227 | — | — | 2 | — | — | — | — | 2 |
| Connective tissue diseases | D003240 | EFO_1001986 | M35 | 1 | — | — | — | — | 1 |
| Immune system diseases | D007154 | — | D89.9 | 1 | — | — | — | — | 1 |
| Arthritis | D001168 | HP_0001369 | M05-M14 | 1 | — | — | — | — | 1 |
| Autoimmune diseases | D001327 | HP_0002960 | M30-M36 | 1 | — | — | — | — | 1 |
| Rheumatic diseases | D012216 | — | M79.0 | 1 | — | — | — | — | 1 |
Show 24 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Intermittent claudication | D007383 | EFO_0003876 | I73.9 | — | — | — | — | 1 | 1 |
| Lupus nephritis | D008181 | EFO_0005761 | — | — | — | — | — | 1 | 1 |
| Hemophagocytic lymphohistiocytosis | D051359 | — | D76.1 | — | — | — | — | 1 | 1 |
| Retinal neoplasms | D019572 | — | C69.2 | — | — | — | — | 1 | 1 |
| Glycogen storage disease type ii | D006009 | Orphanet_365 | E74.02 | — | — | — | — | 1 | 1 |
| Diabetic neuropathies | D003929 | EFO_1000783 | — | — | — | — | — | 1 | 1 |
| Brain injuries | D001930 | — | S06.9 | — | — | — | — | 1 | 1 |
| Chromosome aberrations | D002869 | Orphanet_68335 | — | — | — | — | — | 1 | 1 |
| Hematopoietic stem cell mobilization | D019650 | — | — | — | — | — | — | 1 | 1 |
| Acute liver failure | D017114 | HP_0004448 | — | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Regramostim |
| INN | regramostim |
| Description | Regramostim is a protein pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Protein |
| Drug class | colony-stimulating factors: granulocyte macrophage colony-stimulating factors (GM-CSF); colony-stimulating factors: macrophage colony-stimulating factors (M-CSF) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2107881 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | KR89Q40F01 (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
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Adverse Events
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225 adverse events reported
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