Docusate
Docusate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| signs and symptoms pathological conditions | D013568 |
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| basic care stool softener | C200263 | 2024-06-14 |
| betr remedies stool softener | OTC monograph not final | 2023-07-07 |
| betr stool softener | OTC monograph not final | 2022-08-12 |
| calming days vegan sunscreen | unapproved drug other | 2024-06-21 |
| chupanzon colon detox | C200263 | 2023-11-16 |
| citranatal 90 dha | unapproved drug other | 2024-01-08 |
| citranatal assure | unapproved drug other | 2024-01-08 |
| citranatal bloom dha | unapproved drug other | 2020-04-06 |
| citranatal dha | unapproved drug other | 2020-07-28 |
| citranatal essence | unapproved drug other | 2020-07-07 |
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Indications
FDA
EMA
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Agency Specific
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
692 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 20 | — | — | 1 | 6 | 27 |
| Infections | D007239 | EFO_0000544 | — | 1 | 3 | 2 | 7 | 4 | 17 |
| Covid-19 | D000086382 | — | U07.1 | 2 | 9 | 3 | 1 | 4 | 17 |
| Syndrome | D013577 | — | — | 3 | 6 | 4 | 1 | 4 | 14 |
| Constipation | D003248 | HP_0002019 | K59.0 | — | 3 | 2 | 6 | 3 | 13 |
| Vitamin d deficiency | D014808 | EFO_0003762 | E55 | 1 | — | — | 2 | 8 | 11 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | — | 1 | 2 | 1 | 5 | 9 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | 2 | 7 | 9 |
| Communicable diseases | D003141 | — | — | 1 | 1 | 2 | 1 | 3 | 8 |
| Colorectal neoplasms | D015179 | — | — | 4 | 2 | — | 1 | 1 | 7 |
Show 81 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | 7 | 20 | 11 | — | 2 | 33 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 5 | 15 | 10 | — | 2 | 28 |
| Lymphoid leukemia | D007945 | — | C91 | 5 | 14 | 10 | — | 2 | 27 |
| Carcinoma | D002277 | — | C80.0 | 7 | 10 | 7 | — | 3 | 24 |
| Lymphoma | D008223 | — | C85.9 | 9 | 13 | 6 | — | — | 23 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | 6 | 12 | 4 | — | 3 | 22 |
| Recurrence | D012008 | — | — | 8 | 13 | 1 | — | 3 | 18 |
| Non-small-cell lung carcinoma | D002289 | — | — | 4 | 9 | 4 | — | 2 | 18 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 3 | 2 | — | 5 | 11 |
| Adenocarcinoma | D000230 | — | — | 3 | 6 | 1 | — | 1 | 10 |
Show 129 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 7 | 8 | — | — | 5 | 16 |
| Multiple myeloma | D009101 | — | C90.0 | 3 | 9 | — | — | 1 | 11 |
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | 3 | 3 | — | — | 6 | 11 |
| Melanoma | D008545 | — | — | 4 | 6 | — | — | 2 | 10 |
| Plasma cell neoplasms | D054219 | — | — | 3 | 7 | — | — | 1 | 9 |
| Myeloid leukemia | D007951 | — | C92 | 3 | 8 | — | — | — | 8 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 1 | 1 | — | — | 6 | 8 |
| Hematologic neoplasms | D019337 | — | — | 2 | 3 | — | — | 2 | 6 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 3 | 1 | — | — | 1 | 5 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 3 | 4 | — | — | — | 5 |
Show 133 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ovarian epithelial carcinoma | D000077216 | — | — | 4 | — | — | — | 1 | 5 |
| Pancreatic ductal carcinoma | D021441 | — | — | 2 | — | — | — | 1 | 3 |
| Blood coagulation disorders | D001778 | EFO_0009314 | D68.9 | 1 | — | — | — | 2 | 3 |
| Hemostatic disorders | D020141 | — | — | 1 | — | — | — | 2 | 3 |
| Sarcoma | D012509 | — | — | 2 | — | — | — | — | 2 |
| Primary myelofibrosis | D055728 | — | D47.4 | 2 | — | — | — | — | 2 |
| Hepatitis c | D006526 | — | B19.2 | 2 | — | — | — | — | 2 |
| Hernia | D006547 | HP_0100790 | K40-K46 | 1 | — | — | — | 1 | 2 |
| Asthma | D001249 | EFO_0000270 | J45 | 1 | — | — | — | 1 | 2 |
| Bipolar disorder | D001714 | EFO_0000289 | F30.9 | 1 | — | — | — | 1 | 2 |
Show 38 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Inflammation | D007249 | MP_0001845 | — | — | — | — | — | 6 | 6 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | — | 4 | 4 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | — | — | — | — | 4 | 4 |
| Intestinal diseases | D007410 | HP_0002242 | K63.9 | — | — | — | — | 4 | 4 |
| Depression | D003863 | — | F33.9 | — | — | — | — | 4 | 4 |
| Gastrointestinal diseases | D005767 | — | — | — | — | — | — | 3 | 3 |
| Anesthesia | D000758 | — | — | — | — | — | — | 3 | 3 |
| Dementia | D003704 | EFO_0003862 | F03 | — | — | — | — | 3 | 3 |
| Pathologic dilatation | D004108 | — | — | — | — | — | — | 3 | 3 |
| Fetal growth retardation | D005317 | EFO_0000495 | — | — | — | — | — | 3 | 3 |
Show 299 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Docusate |
| INN | docusate sodium |
| Description | 1,4-bis(2-ethylhexyl) sulfosuccinate is a diester and an organosulfonic acid. |
| Classification | Small molecule |
| Drug class | Stool softener |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(=O)(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 10041-19-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1477036 |
| ChEBI ID | 534 |
| PubChem CID | 11339 |
| DrugBank | DB11089 |
| UNII ID | F05Q2T2JA0 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Estimated US medical usage
Docusate
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Docusate
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Senna
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Price per prescription (USD)
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 75,749 documents
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Safety
Black-box Warning
Black-box warning for: Citranatal 90 dha, Citranatal assure, Citranatal dha, Citranatal essence, Citranatal harmony, Citranatal harmony 2.1, Citranatal harmony 3.0, Citranatal rx, Ferralet 90, Neonatal complete, Neonatal dha, Prenaissance, Prenaissance plus, Prenate pixie
Adverse Events
Top Adverse Reactions
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16,961 adverse events reported
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