Docusate
Docusate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Events
FDA approval date
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Study first post date
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Completion date
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| signs and symptoms pathological conditions | D013568 |
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| basic care stool softener | OTC monograph not final | 2020-08-20 |
| betr stool softener | OTC monograph not final | 2022-08-12 |
| calming days vegan sunscreen | unapproved drug other | 2023-12-28 |
| chupanzon colon detox | C200263 | 2023-11-16 |
| citranatal 90 dha | unapproved drug other | 2024-01-08 |
| citranatal assure | unapproved drug other | 2024-01-08 |
| citranatal bloom | unapproved drug other | 2024-01-05 |
| citranatal bloom dha | unapproved drug other | 2020-04-06 |
| citranatal dha | unapproved drug other | 2020-07-28 |
| citranatal essence | unapproved drug other | 2020-07-07 |
Show 129 more
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| constipation | HP_0002019 | D003248 | K59.0 |
Agency Specific
FDA
EMA
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
560 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Constipation | D003248 | HP_0002019 | K59.0 | — | 2 | 2 | 5 | 1 | 9 |
| Vitamin d deficiency | D014808 | EFO_0003762 | E55 | — | — | — | 2 | 5 | 7 |
| Infections | D007239 | EFO_0000544 | — | — | 1 | — | 4 | 1 | 6 |
| Covid-19 | D000086382 | — | U07.1 | — | 2 | 2 | 1 | 2 | 6 |
| Colorectal neoplasms | D015179 | — | — | 3 | 2 | — | 1 | — | 5 |
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | 1 | 1 | — | 1 | 2 | 4 |
| Human influenza | D007251 | EFO_0007328 | J11.1 | — | — | 1 | 1 | 1 | 3 |
| Schizophrenia | D012559 | EFO_0000692 | F20 | 1 | — | — | 1 | 1 | 3 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | 1 | 2 | 3 |
| Psychotic disorders | D011618 | — | F20.81 | — | — | — | 2 | 1 | 3 |
Show 30 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 5 | 13 | 8 | — | 1 | 23 |
| Non-small-cell lung carcinoma | D002289 | — | — | 2 | 8 | 4 | — | 2 | 16 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 3 | 6 | 1 | — | — | 6 |
| Malignant mesothelioma | D000086002 | — | — | 3 | 2 | 1 | — | 1 | 5 |
| Hodgkin disease | D006689 | — | C81 | — | 2 | 3 | — | — | 5 |
| Squamous cell carcinoma | D002294 | — | — | 2 | 3 | 1 | — | 1 | 5 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | — | 3 | 2 | — | — | 5 |
| Sickle cell anemia | D000755 | EFO_0000697 | D57 | 3 | — | 1 | — | 1 | 5 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | — | — | 3 | — | 2 | 5 |
| Philadelphia chromosome | D010677 | — | — | — | 3 | 1 | — | — | 4 |
Show 66 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 4 | 2 | — | — | 5 | 9 |
| Multiple myeloma | D009101 | — | C90.0 | 3 | 7 | — | — | 1 | 9 |
| Melanoma | D008545 | — | — | 3 | 5 | — | — | — | 6 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 3 | 1 | — | — | 1 | 5 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 3 | 4 | — | — | — | 5 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 2 | 2 | — | — | 1 | 5 |
| Heart failure | D006333 | HP_0001635 | I50 | 1 | 1 | — | — | 3 | 5 |
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | 2 | — | — | 2 | 4 |
| Obsessive-compulsive disorder | D009771 | EFO_0004242 | F42 | — | 1 | — | — | 3 | 4 |
| Myelodysplastic syndromes | D009190 | — | D46 | 1 | 3 | — | — | — | 3 |
Show 71 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 16 | — | — | — | 3 | 19 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 1 | — | — | — | 4 | 5 |
| Cholangiocarcinoma | D018281 | — | C22.1 | 1 | — | — | — | 2 | 3 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 1 | — | — | — | 2 | 3 |
| Ovarian epithelial carcinoma | D000077216 | — | — | 1 | — | — | — | 1 | 2 |
| Adenocarcinoma of lung | D000077192 | — | — | 1 | — | — | — | 1 | 2 |
| Pancreatic ductal carcinoma | D021441 | — | — | 1 | — | — | — | 1 | 2 |
| Primary myelofibrosis | D055728 | — | D47.4 | 2 | — | — | — | — | 2 |
| Asthma | D001249 | EFO_0000270 | J45 | 1 | — | — | — | 1 | 2 |
| Bipolar disorder | D001714 | EFO_0000289 | F30.9 | 1 | — | — | — | 1 | 2 |
Show 23 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 7 | 7 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | — | — | — | — | 4 | 4 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | — | 3 | 3 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | — | — | — | 3 | 3 |
| Chronic renal insufficiency | D051436 | — | N18 | — | — | — | — | 3 | 3 |
| Anesthesia | D000758 | — | — | — | — | — | — | 3 | 3 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | — | — | — | 3 | 3 |
| Dementia | D003704 | EFO_0003862 | F03 | — | — | — | — | 3 | 3 |
| Fetal growth retardation | D005317 | EFO_0000495 | — | — | — | — | — | 3 | 3 |
| Anxiety | D001007 | EFO_0005230 | F41.1 | — | — | — | — | 3 | 3 |
Show 161 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Docusate |
| INN | docusate sodium |
| Description | 1,4-bis(2-ethylhexyl) sulfosuccinate is a diester and an organosulfonic acid. |
| Classification | Small molecule |
| Drug class | Stool softener |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(=O)(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 10041-19-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1477036 |
| ChEBI ID | 534 |
| PubChem CID | 11339 |
| DrugBank | DB11089 |
| UNII ID | F05Q2T2JA0 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
Revenue by drug
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Estimated US medical usage
Docusate
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Docusate
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Senna
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Price per prescription (USD)
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,280 documents
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Safety
Black-box Warning
Black-box warning for: Citranatal 90 dha, Citranatal assure, Citranatal bloom, Citranatal dha, Citranatal essence, Citranatal harmony, Citranatal harmony 2.1, Citranatal harmony 3.0, Citranatal rx, Ferralet 90, Neonatal complete, Neonatal dha, Prenaissance, Prenaissance plus, Prenate pixie
Adverse Events
Top Adverse Reactions
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10,666 adverse events reported
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