Docusate
Docusate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Events
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| signs and symptoms pathological conditions | D013568 |
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| basic care stool softener | C200263 | 2024-06-14 |
| calming days vegan sunscreen | C200263 | 2025-12-29 |
| chupanzon colon detox | C200263 | 2023-11-16 |
| citranatal assure | unapproved drug other | 2026-01-08 |
| citranatal bloom dha | unapproved drug other | 2020-04-06 |
| citranatal essence | unapproved drug other | 2020-07-07 |
| citranatal harmony | unapproved drug other | 2012-01-18 |
| citranatal harmony 2.1 | unapproved drug other | 2019-05-14 |
| clear stool softener | C200263 | 2024-12-20 |
| colace | C200263 | 2026-09-09 |
Show 126 more
Indications
FDA
EMA
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Agency Specific
FDA
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
931 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 22 | — | — | 2 | 7 | 31 |
| Leishmaniasis | D007896 | EFO_0005044 | B55 | 1 | 11 | 12 | 4 | 1 | 25 |
| Cutaneous leishmaniasis | D016773 | — | B55.1 | 1 | 10 | 11 | 2 | 1 | 22 |
| Covid-19 | D000086382 | — | U07.1 | 2 | 8 | 3 | 1 | 4 | 17 |
| Infections | D007239 | EFO_0000544 | — | 1 | 2 | 1 | 8 | 5 | 16 |
| Heart failure | D006333 | EFO_0003144 | I50 | 2 | 3 | 3 | 3 | 5 | 15 |
| Colorectal neoplasms | D015179 | — | — | 8 | 3 | 1 | 1 | 2 | 13 |
| Constipation | D003248 | — | K59.0 | — | 4 | 3 | 6 | 2 | 13 |
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | 1 | — | 1 | 1 | 10 | 13 |
| Syndrome | D013577 | — | — | 3 | 2 | 2 | 1 | 6 | 12 |
Show 103 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 5 | 18 | 10 | — | 3 | 31 |
| Non-small-cell lung carcinoma | D002289 | — | — | 7 | 14 | 4 | — | 2 | 24 |
| Burkitt lymphoma | D002051 | — | C83.7 | 5 | 12 | 7 | — | — | 20 |
| Lung neoplasms | D008175 | — | C34.90 | 4 | 10 | 2 | — | 4 | 17 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 7 | 12 | 2 | — | — | 17 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 3 | 6 | 1 | — | 6 | 15 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 1 | — | 1 | — | 11 | 13 |
| Recurrence | D012008 | — | — | 5 | 5 | 2 | — | 3 | 12 |
| Multiple myeloma | D009101 | — | C90.0 | 4 | 9 | 1 | — | — | 12 |
| Leukemia | D007938 | — | C95 | 3 | 7 | 3 | — | 2 | 10 |
Show 141 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 11 | 8 | — | — | 5 | 20 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 5 | 11 | — | — | — | 13 |
| Melanoma | D008545 | — | — | 4 | 6 | — | — | 2 | 11 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 6 | 6 | — | — | — | 10 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 2 | 2 | — | — | 5 | 9 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 4 | 7 | — | — | — | 8 |
| Myelodysplastic syndromes | D009190 | — | D46 | 4 | 6 | — | — | — | 7 |
| Inflammation | D007249 | MP_0001845 | — | 1 | 1 | — | — | 6 | 7 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | 1 | — | — | 5 | 6 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 4 | 3 | — | — | 1 | 6 |
Show 178 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ovarian epithelial carcinoma | D000077216 | — | — | 3 | — | — | — | 1 | 4 |
| Hepatitis c | D006526 | — | B19.2 | 2 | — | — | — | 1 | 3 |
| Asthma | D001249 | EFO_0000270 | J45 | 1 | — | — | — | 2 | 3 |
| Gastrointestinal microbiome | D000069196 | — | — | 1 | — | — | — | 2 | 3 |
| Transcranial magnetic stimulation | D050781 | — | — | 1 | — | — | — | 2 | 3 |
| Sarcoma | D012509 | — | — | 1 | — | — | — | 1 | 2 |
| Hernia | D006547 | — | K40-K46 | 1 | — | — | — | 1 | 2 |
| Diabetic neuropathies | D003929 | EFO_1000783 | — | 1 | — | — | — | 1 | 2 |
| Bipolar disorder | D001714 | EFO_0000289 | F30.9 | 1 | — | — | — | 1 | 2 |
| Severe acute respiratory syndrome-related coronavirus | D045473 | NCBITaxon_227859 | — | 2 | — | — | — | — | 2 |
Show 57 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anxiety disorders | D001008 | EFO_0006788 | F41.1 | — | — | — | — | 5 | 5 |
| Anxiety | D001007 | EFO_0005230 | F41.1 | — | — | — | — | 5 | 5 |
| Depression | D003863 | — | F33.9 | — | — | — | — | 4 | 4 |
| Major depressive disorder | D003865 | EFO_0003761 | F22 | — | — | — | — | 4 | 4 |
| Postmenopause | D017698 | — | — | — | — | — | — | 3 | 3 |
| Anesthesia | D000758 | — | — | — | — | — | — | 3 | 3 |
| Fetal growth retardation | D005317 | EFO_0000495 | — | — | — | — | — | 3 | 3 |
| Motor activity | D009043 | EFO_0003940 | — | — | — | — | — | 3 | 3 |
| Pathologic dilatation | D004108 | — | — | — | — | — | — | 3 | 3 |
| Xerostomia | D014987 | — | K11.7 | — | — | — | — | 3 | 3 |
Show 306 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Docusate |
| INN | docusate sodium |
| Description | 1,4-bis(2-ethylhexyl) sulfosuccinate is a diester and an organosulfonic acid. |
| Classification | Small molecule |
| Drug class | Stool softener |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(=O)(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 10041-19-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1477036 |
| ChEBI ID | 534 |
| PubChem CID | 11339 |
| DrugBank | DB11089 |
| UNII ID | F05Q2T2JA0 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Estimated US medical usage
Docusate
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Docusate
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Price per prescription (USD)
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 9,999 documents
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Safety
Black-box Warning
Black-box warning for: Citranatal assure, Citranatal essence, Citranatal harmony, Citranatal harmony 2.1, Ferralet 90
Adverse Events
Top Adverse Reactions
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35,232 adverse events reported
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