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Drug ReportsVicriviroc
Vicriviroc
Vicriviroc is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target C-C chemokine receptor type 5.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
128 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
RecurrenceD012008———1———1
CarcinomaD002277—C80.0—1———1
Lung neoplasmsD008175—C34.90—1———1
Small cell lung carcinomaD055752———1———1
Neuroendocrine tumorsD018358EFO_1001901D3A.8—1———1
Neuroendocrine carcinomaD018278———1———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameVicriviroc
INNvicriviroc
Description
(4,6-dimethyl-5-pyrimidinyl)-[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-1-piperidinyl]methanone is a member of (trifluoromethyl)benzenes.
Classification
Small molecule
Drug classantivirals; antivirals, chemokine receptor (CCR) antagonists
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
COC[C@@H](c1ccc(C(F)(F)F)cc1)N1CCN(C2(C)CCN(C(=O)c3c(C)ncnc3C)CC2)C[C@@H]1C
Identifiers
PDB—
CAS-ID306296-47-9
RxCUI—
ChEMBL IDCHEMBL82301
ChEBI ID—
PubChem CID3009355
DrugBank—
UNII IDTL515DW4QS (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CCR5
CCR5
Organism
Homo sapiens
Gene name
CCR5
Gene synonyms
CMKBR5
NCBI Gene ID
Protein name
C-C chemokine receptor type 5
Protein synonyms
C-C motif chemokine receptor 5 A159A, CD195, chemokine (C-C motif) receptor 5, chemokine receptor CCR5, chemokine recptor CCR5 Delta32, CHEMR13, HIV-1 fusion coreceptor, mutant C-C motif chemokine receptor
Uniprot ID
Mouse ortholog
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Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 687 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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13 adverse events reported
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