Benzimidazole
Benzimidazole is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target fMet-Leu-Phe receptor.
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2516 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 332 | 4 | 3 | 11 | 6 | 353 |
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | 41 | 35 | 83 | 85 | 57 | 289 |
| Lymphoma | D008223 | — | C85.9 | 74 | 113 | 34 | 2 | 9 | 203 |
| Infections | D007239 | EFO_0000544 | — | 10 | 17 | 29 | 97 | 50 | 194 |
| Hypertension | D006973 | EFO_0000537 | I10 | 13 | 7 | 46 | 47 | 48 | 161 |
| Peptic esophagitis | D004942 | EFO_1001095 | — | 11 | 11 | 43 | 23 | 14 | 99 |
| Ulcer | D014456 | MPATH_579 | — | 6 | 13 | 45 | 23 | 14 | 96 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 33 | 39 | 27 | 1 | 3 | 94 |
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | 1 | 6 | 7 | 35 | 41 | 89 |
| Helicobacter infections | D016481 | EFO_1000961 | — | 2 | 6 | 18 | 35 | 20 | 78 |
Show 271 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 38 | 42 | 21 | — | 4 | 91 |
| Mantle-cell lymphoma | D020522 | — | C83.1 | 23 | 31 | 10 | — | 2 | 58 |
| B-cell lymphoma | D016393 | — | — | 26 | 30 | 4 | — | 2 | 53 |
| Neoplasms | D009369 | — | C80 | 30 | 9 | 4 | — | 7 | 47 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 17 | 29 | 6 | — | — | 41 |
| Multiple myeloma | D009101 | — | C90.0 | 22 | 27 | 1 | — | — | 37 |
| Plasma cell neoplasms | D054219 | — | — | 18 | 25 | 1 | — | — | 32 |
| B-cell lymphoma marginal zone | D018442 | — | C88.4 | 12 | 12 | 6 | — | 3 | 30 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 5 | 3 | 2 | — | 5 | 15 |
| T-cell lymphoma | D016399 | — | — | 6 | 7 | 1 | — | — | 12 |
Show 111 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Waldenstrom macroglobulinemia | D008258 | — | C88.0 | 6 | 7 | — | — | 1 | 13 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 6 | 8 | — | — | — | 11 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 5 | 6 | — | — | — | 8 |
| Prostatic neoplasms | D011471 | — | C61 | 5 | 2 | — | — | — | 7 |
| Burkitt lymphoma | D002051 | — | C83.7 | 4 | 4 | — | — | — | 7 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | 5 | 2 | — | — | — | 6 |
| Myelodysplastic syndromes | D009190 | — | D46 | 3 | 5 | — | — | — | 6 |
| Hematologic neoplasms | D019337 | — | — | 3 | 3 | — | — | — | 5 |
| Mycoses | D009181 | — | B35-B49 | 3 | 3 | — | — | — | 5 |
| Sezary syndrome | D012751 | — | C84.1 | 4 | 2 | — | — | — | 5 |
Show 122 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pharmacokinetics | D010599 | — | — | 12 | — | — | — | — | 12 |
| Therapeutic equivalency | D013810 | — | — | 6 | — | — | — | — | 6 |
| Atopic dermatitis | D003876 | EFO_0000274 | L20 | 6 | — | — | — | — | 6 |
| Hepatitis c | D006526 | — | B19.2 | 4 | — | — | — | — | 4 |
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | 1 | — | — | — | 2 | 3 |
| Pharmacological phenomena | D000069437 | — | — | 3 | — | — | — | — | 3 |
| Autoimmune diseases | D001327 | EFO_0000540 | M30-M36 | 3 | — | — | — | — | 3 |
| Blood coagulation disorders | D001778 | EFO_0009314 | D68.9 | 1 | — | — | — | 1 | 2 |
| Hemostatic disorders | D020141 | — | — | 1 | — | — | — | 1 | 2 |
| Eczema | D004485 | — | L30.9 | 2 | — | — | — | — | 2 |
Show 74 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | — | 4 | 4 |
| Coinfection | D060085 | — | — | — | — | — | — | 4 | 4 |
| Sudden death cardiac | D016757 | EFO_0004278 | — | — | — | — | — | 3 | 3 |
| Death | D003643 | PATO_0001422 | — | — | — | — | — | 3 | 3 |
| Echinococcosis | D004443 | EFO_0007245 | B67 | — | — | — | — | 3 | 3 |
| Frailty | D000073496 | — | R53.1 | — | — | — | — | 2 | 2 |
| Therapeutic chemoembolization | D016461 | — | — | — | — | — | — | 2 | 2 |
| Trematode infections | D014201 | EFO_1001438 | B66.5 | — | — | — | — | 2 | 2 |
| Mortality | D009026 | EFO_0004352 | — | — | — | — | — | 2 | 2 |
| Hepatic echinococcosis | D004444 | — | B67.8 | — | — | — | — | 2 | 2 |
Show 92 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Benzimidazole |
| INN | _ |
| Description | 1H-benzimidazole is the 1H-tautomer of benzimidazole. It is a benzimidazole and a polycyclic heteroarene. It is a conjugate acid of a benzimidazolide. It is a tautomer of a 4H-benzimidazole, a 2H-benzimidazole and a 3aH-benzimidazole. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | c1ccc2[nH]cnc2c1 |
Identifiers
| PDB | — |
| CAS-ID | 51-17-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL306226 |
| ChEBI ID | 41275 |
| PubChem CID | 5798 |
| DrugBank | DB02962 |
| UNII ID | E24GX49LD8 (ChemIDplus, GSRS) |
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