Benzimidazole
Benzimidazole is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target fMet-Leu-Phe receptor.
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2458 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | 3 | 2 | 20 | 25 | 3 | 52 |
| Peptic esophagitis | D004942 | EFO_1001095 | — | — | 1 | 7 | 7 | — | 14 |
| Esophagitis | D004941 | HP_0100633 | K20 | 1 | 1 | 7 | 5 | — | 13 |
| Healthy volunteers/patients | — | — | — | 10 | — | — | 2 | — | 12 |
| Stomach ulcer | D013276 | — | K25 | — | — | 9 | 1 | — | 10 |
| Heartburn | D006356 | — | R12 | — | — | 3 | 6 | — | 9 |
| Dyspepsia | D004415 | EFO_0008533 | K30 | — | 1 | 3 | 2 | — | 6 |
| Barrett esophagus | D001471 | EFO_0000280 | K22.7 | 1 | — | 1 | 3 | — | 5 |
| Non-erosive reflux disease | D000096663 | — | — | — | — | 2 | 1 | — | 3 |
| Laryngopharyngeal reflux | D057045 | EFO_1001355 | — | — | — | — | 2 | — | 2 |
Show 15 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ulcer | D014456 | MPATH_579 | — | 1 | — | 11 | — | — | 12 |
| Gastrointestinal diseases | D005767 | — | — | — | — | 6 | — | — | 6 |
| Duodenal ulcer | D004381 | EFO_0004607 | K26 | — | — | 5 | — | — | 5 |
| Peptic ulcer | D010437 | — | K27 | 2 | — | 3 | — | — | 5 |
| Mantle-cell lymphoma | D020522 | — | C83.1 | 1 | — | 1 | — | — | 2 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | 2 | — | — | 2 |
| Peptic ulcer hemorrhage | D010438 | — | — | — | — | 2 | — | — | 2 |
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | — | 2 | — | — | 2 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | — | 2 | — | — | 2 |
| Low back pain | D017116 | — | M54.5 | — | — | 2 | — | — | 2 |
Show 15 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Asthma | D001249 | EFO_0000270 | J45 | — | 2 | — | — | — | 2 |
| Waldenstrom macroglobulinemia | D008258 | — | C88.0 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Therapeutic equivalency | D013810 | — | — | 3 | — | — | — | — | 3 |
| Covid-19 | D000086382 | — | U07.1 | 1 | — | — | — | — | 1 |
| Infections | D007239 | EFO_0000544 | — | 1 | — | — | — | — | 1 |
| Communicable diseases | D003141 | — | — | 1 | — | — | — | — | 1 |
| Chronic pain | D059350 | — | — | 1 | — | — | — | — | 1 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | 1 | — | — | — | — | 1 |
| Metabolism | D008660 | GO_0008152 | — | 1 | — | — | — | — | 1 |
| Juvenile arthritis | D001171 | EFO_1002007 | M08 | 1 | — | — | — | — | 1 |
| Arthritis | D001168 | EFO_0005856 | M05-M14 | 1 | — | — | — | — | 1 |
| Pancreatitis | D010195 | EFO_0000278 | K85 | 1 | — | — | — | — | 1 |
Show 4 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Metabolic diseases | D008659 | EFO_0000589 | E88.9 | — | — | — | — | 1 | 1 |
| Calcium metabolism disorders | D002128 | EFO_0005769 | E83.5 | — | — | — | — | 1 | 1 |
| Rhinitis | D012220 | EFO_0008521 | J31 | — | — | — | — | 1 | 1 |
| Common cold | D003139 | EFO_0007214 | J00 | — | — | — | — | 1 | 1 |
| Vasomotor rhinitis | D012223 | EFO_0007533 | J30.0 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Benzimidazole |
| INN | _ |
| Description | 1H-benzimidazole is the 1H-tautomer of benzimidazole. It is a benzimidazole and a polycyclic heteroarene. It is a conjugate acid of a benzimidazolide. It is a tautomer of a 4H-benzimidazole, a 2H-benzimidazole and a 3aH-benzimidazole. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | c1ccc2[nH]cnc2c1 |
Identifiers
| PDB | — |
| CAS-ID | 51-17-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL306226 |
| ChEBI ID | 41275 |
| PubChem CID | 5798 |
| DrugBank | DB02962 |
| UNII ID | E24GX49LD8 (ChemIDplus, GSRS) |
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Safety
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