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Drug ReportsBenzimidazole
Benzimidazole
Benzimidazole is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target fMet-Leu-Phe receptor.
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FDA approval date
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Study first post date
Last update post date
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Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
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EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
P: Antiparasitic products, insecticides and repellents
P02: Anthelmintics
P02C: Antinematodal agents
P02CA: Benzimidazole derivatives, antinematodal
HCPCS
No data
Clinical
Clinical Trials
2444 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Juvenile arthritisD001171EFO_1002007M0811
ArthritisD001168EFO_0005856M05-M1411
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Multiple myelomaD009101C90.0122
Plasma cell neoplasmsD054219122
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients33
Atopic dermatitisD003876EFO_0000274L2011
EczemaD004485L30.911
DermatitisD003872L30.911
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBenzimidazole
INN_
Description
1H-benzimidazole is the 1H-tautomer of benzimidazole. It is a benzimidazole and a polycyclic heteroarene. It is a conjugate acid of a benzimidazolide. It is a tautomer of a 4H-benzimidazole, a 2H-benzimidazole and a 3aH-benzimidazole.
Classification
Small molecule
Drug class
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Structure (InChI/SMILES or Protein Sequence)
c1ccc2[nH]cnc2c1
Identifiers
PDB
CAS-ID51-17-2
RxCUI
ChEMBL IDCHEMBL306226
ChEBI ID41275
PubChem CID5798
DrugBankDB02962
UNII IDE24GX49LD8 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
FPR1
FPR1
Organism
Homo sapiens
Gene name
FPR1
Gene synonyms
NCBI Gene ID
Protein name
fMet-Leu-Phe receptor
Protein synonyms
fMLP receptor, FPR, N-formyl peptide receptor, N-formylpeptide chemoattractant receptor
Uniprot ID
Mouse ortholog
Fpr1 (14293)
fMet-Leu-Phe receptor (Q3UV01)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1 adverse events reported
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