Benzimidazole
Benzimidazole is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target fMet-Leu-Phe receptor.
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | 4 | — | 4 | 2 | — | 10 |
| Sleep initiation and maintenance disorders | D007319 | — | F51.01 | — | — | — | 1 | — | 1 |
| Sleep wake disorders | D012893 | — | G47 | — | — | — | 1 | — | 1 |
| Parasomnias | D020447 | — | G47.5 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 12 | — | 1 | — | — | 13 |
| Lymphoma | D008223 | — | C85.9 | 1 | 1 | 3 | — | — | 5 |
| Peptic esophagitis | D004942 | EFO_1001095 | — | 2 | — | 1 | — | — | 3 |
| Peripheral arterial disease | D058729 | EFO_0004265 | — | — | — | 1 | — | — | 1 |
| B-cell lymphoma marginal zone | D018442 | — | C88.4 | — | — | 1 | — | — | 1 |
| Follicular lymphoma | D008224 | — | C82 | — | — | 1 | — | — | 1 |
| Mantle-cell lymphoma | D020522 | — | C83.1 | — | — | 1 | — | — | 1 |
| Leukemia | D007938 | — | C95 | — | — | 1 | — | — | 1 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | — | — | 1 | — | — | 1 |
| Lymphoid leukemia | D007945 | — | C91 | — | — | 1 | — | — | 1 |
Show 8 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 1 | 1 | — | — | — | 2 |
| Multiple myeloma | D009101 | — | C90.0 | — | 1 | — | — | — | 1 |
| Plasma cell neoplasms | D054219 | — | — | — | 1 | — | — | — | 1 |
| Glioblastoma | D005909 | EFO_0000515 | — | 1 | 1 | — | — | — | 1 |
| Glioma | D005910 | EFO_0000520 | — | 1 | 1 | — | — | — | 1 |
| Gliosarcoma | D018316 | — | — | 1 | 1 | — | — | — | 1 |
| Astrocytoma | D001254 | EFO_0000271 | — | 1 | 1 | — | — | — | 1 |
| Diffuse intrinsic pontine glioma | D000080443 | — | — | 1 | 1 | — | — | — | 1 |
| Optic nerve glioma | D020339 | — | — | 1 | 1 | — | — | — | 1 |
| Brain stem neoplasms | D020295 | EFO_1001767 | — | 1 | 1 | — | — | — | 1 |
Show 3 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 1 | — | — | — | — | 1 |
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | 1 | — | — | — | — | 1 |
| Crohn disease | D003424 | EFO_0000384 | K50 | 1 | — | — | — | — | 1 |
| Colitis | D003092 | EFO_0003872 | K52.9 | 1 | — | — | — | — | 1 |
| Ulcer | D014456 | MPATH_579 | — | 1 | — | — | — | — | 1 |
| Psoriasis | D011565 | EFO_0000676 | L40 | 1 | — | — | — | — | 1 |
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | 1 | — | — | — | — | 1 |
| Arthritis | D001168 | EFO_0005856 | M05-M14 | 1 | — | — | — | — | 1 |
| Pharmacokinetics | D010599 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | — | — | — | 3 | 3 |
| Venous thromboembolism | D054556 | EFO_0004286 | I74 | — | — | — | — | 1 | 1 |
| Thromboembolism | D013923 | — | — | — | — | — | — | 1 | 1 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | — | 1 | 1 |
| Schizophrenia | D012559 | EFO_0000692 | F20 | — | — | — | — | 1 | 1 |
| Sudden death cardiac | D016757 | EFO_0004278 | — | — | — | — | — | 1 | 1 |
| Death | D003643 | PATO_0001422 | — | — | — | — | — | 1 | 1 |
| Sudden death | D003645 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Benzimidazole |
| INN | _ |
| Description | 1H-benzimidazole is the 1H-tautomer of benzimidazole. It is a benzimidazole and a polycyclic heteroarene. It is a conjugate acid of a benzimidazolide. It is a tautomer of a 4H-benzimidazole, a 2H-benzimidazole and a 3aH-benzimidazole. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | c1ccc2[nH]cnc2c1 |
Identifiers
| PDB | — |
| CAS-ID | 51-17-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL306226 |
| ChEBI ID | 41275 |
| PubChem CID | 5798 |
| DrugBank | DB02962 |
| UNII ID | E24GX49LD8 (ChemIDplus, GSRS) |
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