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Drug ReportsBenzimidazole
Benzimidazole
Benzimidazole is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target fMet-Leu-Phe receptor.
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3M
6M
YTD
1Y
2Y
5Y
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
P: Antiparasitic products, insecticides and repellents
— P02: Anthelmintics
— P02C: Antinematodal agents
— P02CA: Benzimidazole derivatives, antinematodal
HCPCS
No data
Clinical
Clinical Trials
2455 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
B-cell chronic lymphocytic leukemiaD015451—C91.1——3——3
Mantle-cell lymphomaD020522—C83.1—11——2
Non-hodgkin lymphomaD008228—C85.9——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LymphomaD008223—C85.9—1———1
Waldenstrom macroglobulinemiaD008258—C88.0—1———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBenzimidazole
INN_
Description
1H-benzimidazole is the 1H-tautomer of benzimidazole. It is a benzimidazole and a polycyclic heteroarene. It is a conjugate acid of a benzimidazolide. It is a tautomer of a 4H-benzimidazole, a 2H-benzimidazole and a 3aH-benzimidazole.
Classification
Small molecule
Drug class—
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Structure (InChI/SMILES or Protein Sequence)
c1ccc2[nH]cnc2c1
Identifiers
PDB—
CAS-ID51-17-2
RxCUI—
ChEMBL IDCHEMBL306226
ChEBI ID41275
PubChem CID5798
DrugBankDB02962
UNII IDE24GX49LD8 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
FPR1
FPR1
Organism
Homo sapiens
Gene name
FPR1
Gene synonyms
NCBI Gene ID
2357
Protein name
fMet-Leu-Phe receptor
Protein synonyms
fMLP receptor, FPR, N-formyl peptide receptor, N-formylpeptide chemoattractant receptor
Uniprot ID
Q9NS48
Mouse ortholog
Fpr1 (14293)
fMet-Leu-Phe receptor (Q3UV01)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 22,719 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1 adverse events reported
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