Benzimidazole
Benzimidazole is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target fMet-Leu-Phe receptor.
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Clinical
Clinical Trials
18 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Helminthiasis | D006373 | EFO_1001342 | B65-B83 | 1 | — | — | 1 | 2 | 4 |
| Infections | D007239 | EFO_0000544 | — | — | — | 1 | 1 | — | 2 |
| Drug resistance | D004351 | — | Z16.30 | — | — | — | 1 | — | 1 |
| Stomach ulcer | D013276 | — | K25 | — | — | — | 1 | — | 1 |
| Ulcer | D014456 | MPATH_579 | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-erosive reflux disease | D000096663 | — | — | — | — | 1 | — | — | 1 |
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | — | — | 1 | — | — | 1 |
| Esophagitis | D004941 | HP_0100633 | K20 | — | — | 1 | — | — | 1 |
| Communicable diseases | D003141 | — | — | — | — | 1 | — | — | 1 |
| Clostridium infections | D003015 | EFO_1000874 | A05.2 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple myeloma | D009101 | — | C90.0 | — | 1 | — | — | — | 1 |
| Trichuriasis | D014257 | EFO_0007524 | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glioblastoma | D005909 | EFO_0000515 | — | 1 | — | — | — | — | 1 |
| Gliosarcoma | D018316 | — | — | 1 | — | — | — | — | 1 |
| Neurocysticercosis | D020019 | — | — | 1 | — | — | — | — | 1 |
| Cysticercosis | D003551 | EFO_0007231 | B69 | 1 | — | — | — | — | 1 |
| Taeniasis | D013622 | EFO_1001433 | B68 | 1 | — | — | — | — | 1 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
| Filariasis | D005368 | — | B74 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hepatic echinococcosis | D004444 | — | B67.8 | — | — | — | — | 2 | 2 |
| Echinococcosis | D004443 | EFO_0007245 | B67 | — | — | — | — | 2 | 2 |
| Recreational drug use | D000084783 | — | — | — | — | — | — | 1 | 1 |
| Glioma | D005910 | EFO_0000520 | — | — | — | — | — | 1 | 1 |
| Diffuse intrinsic pontine glioma | D000080443 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Benzimidazole |
| INN | — |
| Description | 1H-benzimidazole is the 1H-tautomer of benzimidazole. It is a benzimidazole and a polycyclic heteroarene. It is a conjugate acid of a benzimidazolide. It is a tautomer of a 4H-benzimidazole, a 2H-benzimidazole and a 3aH-benzimidazole. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | c1ccc2[nH]cnc2c1 |
Identifiers
| PDB | — |
| CAS-ID | 51-17-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL306226 |
| ChEBI ID | 41275 |
| PubChem CID | 5798 |
| DrugBank | DB02962 |
| UNII ID | — |
Target
Agency Approved
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Trends
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Safety
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Adverse Events
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