PharmaKB logo
Company Reports
Company Reports
Drug Reports
Drug Reports
Disease Reports
Disease Reports
Sets
Sets
Favorites
Favorites
Log in
Log in
AboutPricing
Disease Reportsconstipation
MeSH D003248 - constipation
Favorite
Competitive Landscape
Events Timeline
Commercial
Clinical Trials
Competitive landscape
See list view
D012817:Digestive signs and symptoms
0 Companies
0 Drugs
Success rate
D003248: 
Constipation
47 Companies
20 Drugs
$
Success rate
D000079689:Opioid-induced constipation
0 Companies
0 Drugs
Success rate
Events Timeline
Loading
Commercial
Company Name
Drug Name
Trade Name
Patent Expires
Approval Date
Revenue
Period
Salix PharmaceuticalsMethylnaltrexone Relistor 2024-04-08 2008-04-24   
Plecanatide Trulance 2022-03-28 2017-01-19   
Ascorbic acid, Polyethylene glycol 3350, Ascorbate Moviprep 2024-09-01 2006-08-02   
Ascorbic acid, Polyethylene glycol 3350, Ascorbate Plenvu 2032-03-09 2018-05-04   
TevaLactulose Evalose  1993-05-28   
Lactulose Heptalac  1993-05-28   
Lubiprostone Lubiprostone  2022-01-18   
MylanLinaclotide Linaclotide  2021-02-09   
Polyethylene glycol 3350 Colyte With Flavor Packs  1984-10-26   
AbbVieLinaclotide Constella  2012-11-26   
Linaclotide Linzess 2024-01-28 2012-08-30 $954 M Y2024 
SanofiLactulose Cephulac  1982-01-01   
Lactulose Chronulac  1982-01-01   
Bausch Health CompaniesMethylnaltrexone Relistor  2008-07-01   
Xttrium LaboratoriesLactulose Lactulose  2002-02-21   
TakedaPrucalopride Motegrity  2018-12-14   
Prucalopride Resolor  2009-10-14   
Dr Reddys LaboratoriesLubiprostone Lubiprostone  2022-02-08   
1
2
3
4
5
>
Clinical Trials
Historical Success Rate
Phase 1
48%
11/23
Phase 2
74%
23/31
Phase 3
92%
46/50
Approved: 23Overall Success rate: 33%
All Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Company name
Phase 1
Phase 2
Phase 3
Phase 4
Drug Name
Teva
Replens
Johnson & Johnson
Cisapride,
Articular
AbbVie
Linaclotide
Sanofi
Sennosides
Bausch Health Companies
Methylnaltrexone bromide,
Methylnaltrexone,
DOLCANATIDE,
Arm1,
Arm2
Takeda
Prucalopride,
Benzocaine,
Aspartame,
Sennosides,
Kristalose
Dr Reddys Laboratories
Lubiprostone,
Enoblituzumab
1
2
3
4
>
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use