Sennosides
Sennosides is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| assured natural laxative | OTC monograph not final | 2016-07-28 |
| bekunis natures gentle laxative herbal tea | OTC monograph not final | 2011-03-24 |
| bekunis natures gentle laxative instant tea | OTC monograph not final | 2011-03-21 |
| bekunis natures gentle stimulant laxative | OTC monograph not final | 2011-02-13 |
| best choice senna | OTC monograph final | 2012-11-08 |
| careall sennosides | C200263 | 2024-01-29 |
| caremotion | OTC monograph not final | 2021-11-18 |
| chocolate laxative | OTC monograph not final | 2023-02-10 |
| chocolated laxative | OTC monograph not final | 2023-02-15 |
| chupanzon colon detox | C200263 | 2023-11-16 |
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Clinical
Clinical Trials
41 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Constipation | D003248 | HP_0002019 | K59.0 | — | 2 | 4 | 5 | 5 | 15 |
| Opioid-induced constipation | D000079689 | — | — | — | — | — | 1 | 2 | 3 |
| Colorectal neoplasms | D015179 | — | — | — | — | — | 1 | 1 | 2 |
| Analgesia | D000698 | — | — | — | — | — | 1 | — | 1 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | 1 | — | 1 |
| Lower urinary tract symptoms | D059411 | EFO_0008008 | — | — | — | — | 1 | — | 1 |
| Paralysis | D010243 | HP_0003470 | — | — | — | — | 1 | — | 1 |
| Neoplasms | D009369 | — | C80 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Inflammatory bowel diseases | D015212 | EFO_0003767 | — | — | — | 1 | — | 1 | 2 |
| Colonoscopy | D003113 | — | — | — | 1 | 1 | — | 1 | 2 |
| Fistula | D005402 | — | — | — | — | 2 | — | — | 2 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | — | 1 | — | — | 1 |
| Obstructive lung diseases | D008173 | HP_0006536 | — | — | — | 1 | — | — | 1 |
| Dyspnea | D004417 | HP_0002094 | R06.0 | — | — | 1 | — | — | 1 |
| Rectal neoplasms | D012004 | — | — | — | — | 1 | — | — | 1 |
| Colonic neoplasms | D003110 | — | C18 | — | — | 1 | — | — | 1 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | 1 | — | — | 1 |
| Anemia | D000740 | HP_0001903 | D64.9 | — | — | 1 | — | — | 1 |
Show 3 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Gastroparesis | D018589 | EFO_1000948 | K31.84 | — | 1 | — | — | — | 1 |
| Gastrointestinal diseases | D005767 | — | — | — | 1 | — | — | — | 1 |
| Digestive system diseases | D004066 | HP_0011024 | K92.9 | — | 1 | — | — | — | 1 |
| Healthy volunteers/patients | — | — | — | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fecal incontinence | D005242 | — | R15 | — | — | — | — | 2 | 2 |
| Necrotizing enterocolitis | D020345 | EFO_0003928 | K55.3 | — | — | — | — | 1 | 1 |
| Intestinal obstruction | D007415 | — | K56.60 | — | — | — | — | 1 | 1 |
| Elective surgical procedures | D017558 | — | — | — | — | — | — | 1 | 1 |
| Enterocolitis | D004760 | EFO_1001481 | — | — | — | — | — | 1 | 1 |
| Hirschsprung disease | D006627 | EFO_0004241 | Q43.1 | — | — | — | — | 1 | 1 |
| Colostomy | D003125 | — | — | — | — | — | — | 1 | 1 |
| Meconium ileus | D000074270 | — | P76.0 | — | — | — | — | 1 | 1 |
| Encopresis | D004688 | — | F98.1 | — | — | — | — | 1 | 1 |
| Autistic disorder | D001321 | HP_0000717 | F84.0 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Sennosides |
| INN | — |
| Description | Senna glycoside, also known as sennoside or senna, is a medication used to treat constipation and empty the large intestine before surgery. The medication is taken by mouth or via the rectum. It typically begins working in around 30 minutes when given by rectum and within twelve hours when given by mouth. It is a weaker laxative than bisacodyl and castor oil.
|
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108559 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB11365 |
| UNII ID | — |
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Safety
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Adverse Events
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2,956 adverse events reported
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