DOLCANATIDE
Dolcanatide is a protein pharmaceutical. It is currently being investigated in clinical studies. It is known to target guanylyl cyclase C.
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FDA approval date
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Study first post date
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Commercial
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Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Constipation | D003248 | HP_0002019 | K59.0 | — | 1 | — | — | — | 1 |
| Opioid-induced constipation | D000079689 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | DOLCANATIDE |
| INN | dolcanatide |
| Description | Dolcanatide is a protein pharmaceutical. It is currently being investigated in clinical studies. It is known to target guanylyl cyclase C. |
| Classification | Protein |
| Drug class | peptides |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)C[C@@H]1NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](N)CC(N)=O)CSSC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(N)=O)C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@H](C(=O)N[C@H](CC(C)C)C(=O)O)CSSC[C@@H](C(=O)N[C@H](C(=O)O)C(C)C)NC1=O |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL3545122 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | WU977T914K (ChemIDplus, GSRS) |
Target
Agency Approved
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Variants
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 55 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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