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Company ReportsAkcea Therapeutics

Akcea Therapeutics(AKCA)

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Marketed Drugs

Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Tegsedi	Inotersen	2018-10-05	2025-2031	Amyloidosis , Familial amyloid neuropathies
Waylivra	Volanesorsen	2019-05-03		Hyperlipoproteinemia type i

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

,

,

myelomonocytic leukemia chronic

,

therapeutic equivalency

,

,

,

alzheimer disease

,

squamous cell carcinoma of head and neck

,

myelodysplastic-myeloproliferative diseases

,

,

retinal detachment

,

,

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

multiple sclerosis

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

macular degeneration

,

wet macular degeneration

,

ocular hypertension

,

open-angle glaucoma

,

castration-resistant prostatic neoplasms

,

leukemia myeloid chronic atypical bcr-abl negative

,

myeloid leukemia chronic-phase

,

myeloid leukemia accelerated phase

,

,

esophageal squamous cell carcinoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

uveal neoplasms

,

dissociative disorders

,

central nervous system neoplasms

,

nervous system neoplasms

,

,

alveolar soft part sarcoma

,

cardiovascular abnormalities

,

neuromyelitis optica

,

sezary syndrome

,

large-cell lymphoma anaplastic

,

primary cutaneous anaplastic large cell lymphoma

,

t-cell lymphoma peripheral

,

chronic progressive multiple sclerosis

,

,

vascular stiffness

,

,

,

,

,

pharmacokinetics

,

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

somatoform disorders

,

atherosclerosis

,

primary hyperoxaluria

,

,

germ cell and embryonal neoplasms

,

,

clear cell sarcoma

,

adrenal cortex neoplasms

,

adrenocortical carcinoma

,

desmoplastic small round cell tumor

,

,

,

myelomonocytic leukemia acute

,

small cell lung carcinoma

,

,

dental pulp necrosis

,

renal cell carcinoma

,

mycobacterium infections

,

basal cell carcinoma

,

basal cell nevus syndrome

,

basal cell neoplasms

,

,

hematologic neoplasms

,

myeloproliferative disorders

,

bcr-abl positive chronic myelogenous leukemia

,

,

stomach neoplasms

,

,

parkinson disease

,

metabolic diseases

,

,

myelomonocytic leukemia juvenile

,

critical illness

,

esophageal neoplasms

,

cognitive dysfunction

,

diabetic retinopathy

,

aplastic anemia

,

,

ovarian neoplasms

,

,

b-cell chronic lymphocytic leukemia

,

hidradenitis suppurativa

,

,

hematologic diseases

,

follicular lymphoma

,

human influenza

,

temporomandibular joint disorders

,

glucose metabolism disorders

,

polycystic ovary syndrome

,

diabetic neuropathies

,

retinal diseases

,

,

milk hypersensitivity

,

transitional cell carcinoma

,

meningeal carcinomatosis

,

promyelocytic leukemia acute

,

neuroendocrine tumors

,

,

colonic neoplasms

,

bile duct neoplasms

,

cholangiocarcinoma

,

gallbladder neoplasms

,

biphenotypic leukemia acute

,

,

prolymphocytic leukemia

,

plasma cell leukemia

,

triple negative breast neoplasms

,

ovarian epithelial carcinoma

,

t-cell lymphoma

,

hepatic insufficiency

,

temporomandibular joint dysfunction syndrome

,

,

,

coronavirus infections

,

stomatognathic diseases

,

peripheral nervous system diseases

,

endometrial neoplasms

,

,

post-traumatic stress disorders

,

neurofibromatosis 1

,

neurofibromatoses

,

,

biliary atresia

,

cystic fibrosis

,

exocrine pancreatic insufficiency

,

neurotoxicity syndromes

,

major depressive disorder

,

rhabdomyosarcoma

,

pulmonary tuberculosis

,

post-acute covid-19 syndrome

,

tuberous sclerosis

,

t-cell leukemia

,

cerebrotendinous xanthomatosis

,

,

,

highly active antiretroviral therapy

,

philadelphia chromosome

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

dyskeratosis congenita

,

positron emission tomography computed tomography

,

anxiety disorders

,

bipolar and related disorders

,

,

smoking cessation

,

,

,

dental pulp diseases

,

substance withdrawal syndrome

,

alagille syndrome

,

,

out-of-hospital cardiac arrest

,

primary graft dysfunction

,

,

essential hypertension

,

addictive behavior

,

adrenoleukodystrophy

,

,

,

,

alopecia areata

,

,

,

primary ovarian insufficiency

,

b-cell lymphoma marginal zone

,

refractory anemia with excess of blasts

,

congenital abnormalities

,

,

chronic hepatitis

,

,

,

colorectal neoplasms

,

acquired immunodeficiency syndrome

,

myelodysplastic syndromes

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

communicable diseases

,

myeloid leukemia acute

,

,

lymphoid leukemia

,

,

pancreatic neoplasms

,

prostatic neoplasms

,

,

,

,

myeloid leukemia

,

liver neoplasms

,

,

hodgkin disease

,

immunologic deficiency syndromes

,

graft vs host disease

,

urinary bladder neoplasms

,

,

hypertriglyceridemia

,

oxidative stress

,

gingival recession

,

,

primary myelofibrosis

,

wounds and injuries

,

chronic obstructive pulmonary disease

,

,

,

,

depressive disorder

,

,

bacterial infections

,

hyperlipoproteinemia type i

,

hyperlipidemias

,

traumatic brain injuries

,

coronary disease

,

gastroesophageal reflux

,

nasopharyngeal neoplasms

,

,

hepatocellular carcinoma

,

respiratory insufficiency

,

,

,

,

,

,

,

obstructive lung diseases

,

coronary artery disease

,

myocardial ischemia

,

respiratory tract infections

,

,

,

,

,

,

rectal neoplasms

,

radiation injuries

,

,

chronic hepatitis c

,

,

nasopharyngeal carcinoma

,

urinary calculi

,

osteoradionecrosis

,

adenomatous polyposis coli

,

wasting syndrome

,

,

severe acute respiratory syndrome-related coronavirus

,

severe acute malnutrition

,

,

,

thrombocytopenia

,

interstitial lung diseases

,

organ transplantation

,

,

langerhans-cell histiocytosis

,

,

invasive hydatidiform mole

,

non-muscle invasive bladder neoplasms

,

obstructive sleep apnea

,

sleep apnea syndromes

,

,

,

pathologic processes

,

delayed graft function

,

essential thrombocythemia

,

polycythemia vera

,

,

,

tumor lysis syndrome

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

neuromuscular diseases

,

bacterial skin diseases

,

hyperlipoproteinemia type v

,

hyperlipoproteinemias

,

familial partial lipodystrophy

,

,

,

,

,

cholecystolithiasis

,

cytomegalovirus infections

,

musculoskeletal diseases

,

diabetic nephropathies

,

brachial plexus neuropathies

,

peptic esophagitis

,

,

respiratory tract diseases

,

pancreatic ductal carcinoma

,

pain management

,

sports nutritional physiological phenomena

,

pseudomyxoma peritonei

,

necrotizing enterocolitis

,

,

biliary liver cirrhosis

,

,

bronchiolitis obliterans syndrome

,

healthy volunteers/patients

,

diabetes mellitus

,

,

,

type 2 diabetes mellitus

,

,

insulin resistance

,

kidney diseases

,

,

breast neoplasms

,

kidney transplantation

,

dry eye syndromes

,

,

,

keratoconjunctivitis sicca

,

,

non-small-cell lung carcinoma

,

postoperative pain

,

neoplasm metastasis

,

chronic renal insufficiency

,

,

metabolic syndrome

,

,

renal insufficiency

,

non-hodgkin lymphoma

,

chronic kidney failure

,

knee osteoarthritis

,

,

cardiovascular diseases

,

,

hypersensitivity

,

multiple myeloma

,

,

type 1 diabetes mellitus

,

,

,

ulcerative colitis

,

,

,

,

liver transplantation

,

,

prediabetic state

,

hypercholesterolemia

,

,

,

head and neck neoplasms

,

,

,

plasma cell neoplasms

,

,

,

chronic hepatitis b

,

,

non-alcoholic fatty liver disease

,

,

acute kidney injury

,

uterine cervical neoplasms

,

,

bipolar disorder

,

,

postoperative complications

,

,

glucose intolerance

,

burkitt lymphoma

,

b-cell lymphoma

,

nephrolithiasis

,

,

,

,

general anesthesia

,

rheumatoid arthritis

,

,

adenocarcinoma of lung

,

,

periodontal diseases

,

hyperlipoproteinemia type ii

,

,

,

cardiomyopathies

,

,

reperfusion injury

,

drug interactions

,

opioid-related disorders

,

liver cirrhosis

,

rotator cuff injuries

,

,

postoperative nausea and vomiting

,

,

,

heart transplantation

,

,

anesthesia and analgesia

,

,

bacterial vaginosis

,

vaginal diseases

,

autistic disorder

,

,

,

,

,

premature birth

,

erectile dysfunction

,

hip osteoarthritis

,

surgical blood loss

,

,

,

spinal anesthesia

,

intestinal pseudo-obstruction

,

,

,

systemic scleroderma

,

hematopoietic stem cell transplantation

,

localized scleroderma

,

diffuse scleroderma

,

,

bone marrow diseases

,

,

,

intravenous anesthesia

,

parenteral nutrition

,

,

viral pneumonia

,

,

,

learning disabilities

,

autism spectrum disorder

,

pervasive child development disorders

,

,

,

barrett esophagus

,

,

,

left ventricular hypertrophy

,

,

cardiac arrhythmias

,

dentin sensitivity

,

calcium metabolism disorders

,

myocardial infarction

,

,

,

large b-cell lymphoma diffuse

,

,

papillomavirus infections

,

squamous intraepithelial lesions

,

,

,

drug resistance

,

physiological sexual dysfunction

,

patient compliance

,

renal replacement therapy

,

,

phenylketonurias

,

,

,

,

,

,

,

,

,

,

,

,

bariatric surgery

,

,

iron-deficiency anemia

,

iron deficiencies

,

,

hyperandrogenism

,

,

muscular atrophy

,

protein deficiency

,

sensitivity training groups

,

failure to thrive

,

malabsorption syndromes

,

lipid metabolism

,

,

,

sleep deprivation

,

brain neoplasms

,

female infertility

,

,

,

,

embryo research

,

craniofacial abnormalities

,

,

oropharyngeal neoplasms

,

inflammatory bowel diseases

,

,

biological availability

,

,

inborn errors metabolism

,

environmental biomarkers

,

nociceptive pain

,

,

,

overactive urinary bladder

,

urge urinary incontinence

,

,

,

dietary proteins

,

orthodontic retainers

,

cardiometabolic risk factors

,

,

cytokine release syndrome

,

gastrointestinal neoplasms

,

,

,

cataract extraction

,

capsule opacification

,

sexually transmitted diseases

,

contraception behavior

,

sickle cell anemia

,

hemolytic anemia

,

glycogen storage disease type iii

,

glycogen storage disease

,

,

hyperinsulinism

,

glomerular filtration rate

,

renal circulation

,

renal plasma flow

,

sjogren's syndrome

,

immunosuppression therapy

,

,

corneal diseases

,

nutritional status

,

infant nutritional physiological phenomena

,

noncommunicable diseases

,

,

solanum tuberosum

,

resistant starch

,

dilated cardiomyopathy

,

hiv-associated lipodystrophy syndrome

,

staphylococcal infections

,

,

,

,

,

,

growth disorders

,

aortic dissection

,

acute lung injury

,

hepatic encephalopathy

,

traumatic stress disorders

,

multidrug-resistant tuberculosis

,

,

second primary neoplasms

,

,

irritable bowel syndrome

,

,

,

multiple trauma

,

iga glomerulonephritis

,

,

circulating neoplastic cells

,

intestinal diseases

,

,

,

metabolic bone diseases

,

postmenopausal osteoporosis

,

growth and development

,

mobility limitation

,

,

fuchs' endothelial dystrophy

,

ischemic stroke

,

,

retinopathy of prematurity

,

short bowel syndrome

,

gastrointestinal diseases

,

digestive system diseases

,

food hypersensitivity

,

,

cartilage diseases

,

systemic inflammatory response syndrome

,

,

,

neoplastic cell transformation

,

,

,

radius fractures

,

wrist fractures

,

inguinal hernia

,

,

sedentary behavior

,

emission-computed tomography single-photon

,

radioisotope diagnostic techniques

,

,

dental enamel hypoplasia

,

molar hypomineralization

,

nutritional and metabolic diseases

,

alveolar bone loss

,

cholecystectomy

,

gastroenteritis

,

chronic kidney disease-mineral and bone disorder

,

uterine hemorrhage

,

,

multiple abnormalities

,

actinic keratosis

,

pityriasis rubra pilaris

,

,

,

,

,

,

electroacupuncture

,

,

,

muscle spasticity

,

,

lipid metabolism disorders

,

,

spontaneous abortion

,

induced abortion

,

tissue adhesions

,

afibrinogenemia

,

,

bone resorption

,

high-throughput nucleotide sequencing

,

heat stress disorders

,

,

heat-shock response

,

,

thoracic neoplasms

,

adjuvant chemotherapy

,

,

squamous cell carcinoma

,

pediatric obesity

,

,

inborn genetic diseases

,

body weight changes

,

positron-emission tomography

,

obstructive jaundice

,

,

bile duct diseases

,

urinary incontinence

,

,

,

periodontal pocket

,

periodontal attachment loss

,

,

,

maple syrup urine disease

,

laparoscopic cholecystectomy

,

,

,

menstrual cycle

,

lewy body disease

,

,

,

,

,

,

urinary tract infections

,

heart disease risk factors

,

immediate dental implant loading

,

,

alphapapillomavirus

,

uterine cervical dysplasia

,

chronic periodontitis

,

periapical periodontitis

,

,

,

,

sleep initiation and maintenance disorders

,

,

,

neuroinflammatory diseases

,

,

atopic dermatitis

,

chronic urticaria

,

,

,

familial amyloid neuropathies

,

renal insufficiency

,

cardiovascular diseases

,

hyperlipidemias

,

hyperlipoproteinemias

healthy volunteers/patients

,

hypertriglyceridemia

,

hyperlipidemias

,

hyperlipoproteinemias

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

,

familial partial lipodystrophy

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

non-alcoholic fatty liver disease

,

,

hyperlipoproteinemia type v

,

,

hyperlipoproteinemia type i

,

,

homozygous familial hypercholesterolemia

,

P2y purinoceptor 12

healthy volunteers/patients

cardiovascular diseases

,

hyperlipidemias

,

hyperlipoproteinemias

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