Pelacarsen
Pelacarsen is an oligonucleotide pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
13 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cardiovascular diseases | D002318 | HP_0001626 | — | — | 1 | — | — | — | 1 |
| Hyperlipidemias | D006949 | HP_0003077 | E78.5 | — | 1 | — | — | — | 1 |
| Hyperlipoproteinemias | D006951 | HP_0010980 | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Renal insufficiency | D051437 | HP_0000083 | N19 | 1 | — | — | — | — | 1 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Pelacarsen |
| INN | pelacarsen |
| Description | Pelacarsen is an antisense therapy that is designed to reduce Lipoprotein(a) concentrations in people with high levels of the lipoprotein and who are at risk of cardiovascular disease. It is developed by Ionis and Novartis.
|
| Classification | Oligonucleotide |
| Drug class | antisense oligonucleotides |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4298202 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | LSO9H7UZ90 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Pelacarsen – Ionis Pharmaceuticals
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Estimated US medical usage
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Trends
PubMed Central
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Additional graphs summarizing 270 documents
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Safety
Black-box Warning
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Adverse Events
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17 adverse events reported
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