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Company ReportsPuma Biotechnology

Puma Biotechnology(PBYI)

Puma Biotechnology is a publicly traded biopharmaceutical company (NASDAQ: PBYI) headquartered in Los Angeles, CA.

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Marketed Drugs

Clinical Trials

Financial

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Company Revenue

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*Quarterly sales USD (in millions)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Nerlynx	Neratinib	2017-07-17	2025-2031	Breast neoplasms

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

hematologic neoplasms

,

pancreatic neoplasms

,

myeloproliferative disorders

,

non-hodgkin lymphoma

,

primary myelofibrosis

,

multiple myeloma

,

precursor cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia chronic

,

,

hodgkin disease

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia chronic-phase

,

myeloid leukemia accelerated phase

,

,

,

,

,

ovarian epithelial carcinoma

,

,

hepatic insufficiency

,

esophageal neoplasms

,

gastrointestinal neoplasms

,

,

neoplasm metastasis

,

triple negative breast neoplasms

,

brain neoplasms

,

non-small-cell lung carcinoma

,

,

stomach neoplasms

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

,

colorectal neoplasms

,

,

ovarian neoplasms

,

inflammatory breast neoplasms

,

neurofibromatosis 2

,

acoustic neuroma

,

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

hemangiosarcoma

,

hereditary sensory and autonomic neuropathies

,

,

,

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

endometrial neoplasms

,

fallopian tube neoplasms

,

lobular carcinoma

,

invasive hydatidiform mole

,

pancreatic ductal carcinoma

,

ductal carcinoma

,

,

,

adenosquamous carcinoma

,

breast neoplasms

,

,

biliary tract neoplasms

,

uterine cervical neoplasms

,

urinary bladder neoplasms

,

neoadjuvant therapy

therapeutic equivalency

,

,

,

communicable diseases

,

,

alzheimer disease

,

,

juvenile arthritis

,

,

,

chronic pancreatitis

,

pharmacokinetics

,

exercise-induced asthma

,

hematologic neoplasms

,

,

waldenstrom macroglobulinemia

,

,

gastrointestinal diseases

,

,

,

mantle-cell lymphoma

,

,

peptic ulcer hemorrhage

,

rheumatoid arthritis

,

,

,

digestive system diseases

,

digestive signs and symptoms

,

simian acquired immunodeficiency syndrome

,

eosinophilic esophagitis

,

esophageal neoplasms

,

precancerous conditions

,

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

gastrointestinal hemorrhage

,

,

,

zollinger-ellison syndrome

,

,

gastroesophageal reflux

,

peptic esophagitis

,

,

healthy volunteers/patients

,

,

,

,

barrett esophagus

,

non-erosive reflux disease

,

laryngopharyngeal reflux

,

,

,

,

,

atrophic gastritis

,

,

,

,

bariatric surgery

,

critical illness

,

,

,

pathologic constriction

,

,

,

metabolic diseases

,

calcium metabolism disorders

,

,

,

vasomotor rhinitis

pancreatic ductal carcinoma

,

pancreatic neoplasms

,

,

acinar cell carcinoma

,

myeloid leukemia acute

myelodysplastic syndromes

,

,

,

large b-cell lymphoma diffuse

,

multiple myeloma

,

plasma cell neoplasms

,

non-hodgkin lymphoma

,

,

b-cell lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

small cell lung carcinoma

,

neuroendocrine carcinoma

,

breast neoplasms

,

myeloid leukemia

,

ulcerative colitis

,

,

,

rheumatoid arthritis

,

myeloid leukemia acute

,

atopic dermatitis

,

hidradenitis suppurativa

,

,

,

,

pathologic constriction

,

inflammatory bowel diseases

,

intestinal diseases

healthy volunteers/patients

,

,

postmenopausal osteoporosis

,

central nervous system neoplasms

,

stomach neoplasms

,

brain neoplasms

,

medulloblastoma

,

thyroid neoplasms

,

,

,

,

endometrial neoplasms

,

renal cell carcinoma

,

,

non-hodgkin lymphoma

,

biliary tract neoplasms

,

,

prostatic neoplasms

,

ovarian epithelial carcinoma

,

pancreatic ductal carcinoma

,

,

large b-cell lymphoma diffuse

,

urologic neoplasms

,

esophageal neoplasms

,

non-muscle invasive bladder neoplasms

,

,

inflammatory breast neoplasms

,

extranodal nk-t-cell lymphoma

,

sezary syndrome

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

head and neck neoplasms

,

hodgkin disease

,

large-cell lymphoma immunoblastic

,

synovial sarcoma

,

respiratory tract diseases

,

,

respiratory tract neoplasms

,

thoracic neoplasms

,

,

squamous cell neoplasms

,

adolescent development

,

small cell carcinoma

,

b-cell lymphoma marginal zone

,

large-cell lymphoma anaplastic

,

precursor cell lymphoblastic leukemia-lymphoma

,

follicular lymphoma

,

hepatocellular carcinoma

,

liver neoplasms

,

malignant pleural effusion

,

mantle-cell lymphoma

,

b-cell lymphoma

,

kidney neoplasms

,

non-small-cell lung carcinoma

,

,

pancreatic neoplasms

,

,

neoplasm metastasis

,

colorectal neoplasms

,

ovarian neoplasms

,

urinary bladder neoplasms

,

cholangiocarcinoma

,

peritoneal neoplasms

,

fallopian tube neoplasms

,

colonic neoplasms

,

,

rectal neoplasms

,

transitional cell carcinoma

,

gallbladder neoplasms

,

female genital neoplasms

,

pelvic neoplasms

,

uterine cervical neoplasms

,

gastrointestinal neoplasms

,

unknown primary neoplasms

,

digestive system neoplasms

,

rectal diseases

,

gastrointestinal diseases

,

intestinal neoplasms

,

digestive system diseases

,

colonic diseases

,

intestinal diseases

,

breast neoplasms

chronic obstructive pulmonary disease

,

respiratory aspiration

,

healthy volunteers/patients

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

triple negative breast neoplasms

,

kidney neoplasms

,

b-cell lymphoma

,

fallopian tube neoplasms

,

follicular lymphoma

,

pancreatic neoplasms

,

endometrial neoplasms

,

stomach neoplasms

,

esophageal neoplasms

,

gastrointestinal neoplasms

,

,

urinary bladder neoplasms

,

uterine cervical neoplasms

,

biliary tract neoplasms

,

gallbladder neoplasms

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

prostatic neoplasms

,

non-small-cell lung carcinoma

,

,

colorectal neoplasms

,

renal cell carcinoma

,

breast neoplasms

,

non-hodgkin lymphoma

,

,

,

essential hypertension

,

castration-resistant prostatic neoplasms

,

gastrointestinal stromal tumors

,

,

,

,

,

neoplasm metastasis

,

erectile dysfunction

,

large b-cell lymphoma diffuse

,

macular degeneration

,

,

hookworm infections

,

,

ancylostomiasis

,

ischemic stroke

,

,

cerebrovascular disorders

,

transient ischemic attack

,

thromboembolism

,

,

,

,

,

acute coronary syndrome

,

,

venous thromboembolism

,

atrial fibrillation

,

,

,

,

,

healthcare-associated pneumonia

,

bacterial pneumonia

,

community-acquired pneumonia

,

thyroid neoplasms

,

thyroid diseases

,

retinal diseases

,

wet macular degeneration

,

retinal degeneration

,

,

,

Polyglycolic acid

renal cell carcinoma

,

digestive system neoplasms

,

gastrointestinal stromal tumors

,

neoplasm metastasis

,

colonic neoplasms

,

rectal neoplasms

,

ovarian neoplasms

,

,

colorectal neoplasms

,

,

pancreatic neoplasms

,

stomach neoplasms

,

,

,

hereditary autoinflammatory diseases

,

,

familial mediterranean fever

Globulin, immune

hematologic neoplasms

,

,

neoplasm metastasis

,

b-cell leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

biphenotypic leukemia acute

,

,

,

acquired immunodeficiency syndrome

,

,

immunologic deficiency syndromes

,

,

squamous cell carcinoma

,

malignant fibrous histiocytoma

,

pancreatic neoplasms

,

stomach neoplasms

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

t-cell lymphoma

,

endometrial neoplasms

,

uterine cervical neoplasms

,

myelodysplastic syndromes

,

myelodysplastic-myeloproliferative diseases

,

b-cell lymphoma

,

non-small-cell lung carcinoma

,

,

plasma cell neoplasms

,

small cell lung carcinoma

,

b-cell lymphoma marginal zone

,

squamous cell carcinoma of head and neck

,

mantle-cell lymphoma

,

lymphoproliferative disorders

,

,

burkitt lymphoma

,

,

breast neoplasms

,

triple negative breast neoplasms

,

esophageal neoplasms

,

immunoglobulin light-chain amyloidosis

,

,

reactive arthritis

,

residual neoplasm

,

myeloid leukemia

,

myeloproliferative disorders

,

lymphatic diseases

,

intestinal neoplasms

,

colonic neoplasms

,

rectal neoplasms

,

,

hairy cell leukemia

,

smoldering multiple myeloma

,

prostatic neoplasms

,

urinary bladder neoplasms

,

uterine neoplasms

,

waldenstrom macroglobulinemia

,

choroidal effusions

,

knee osteoarthritis

,

blastic plasmacytoid dendritic cell neoplasm

,

hypersensitivity

,

neoadjuvant therapy

,

female genital neoplasms

,

,

non-hodgkin lymphoma

,

,

large b-cell lymphoma diffuse

,

b-cell chronic lymphocytic leukemia

,

colorectal neoplasms

,

follicular lymphoma

,

myeloid leukemia acute

,

fallopian tube neoplasms

,

multiple myeloma

,

ovarian neoplasms

,

,

musculoskeletal diseases

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

peritoneal neoplasms

,

brain neoplasms

,

,

juvenile arthritis

,

,

papulosquamous skin diseases

,

,

macular degeneration

,

wet macular degeneration

,

lymphoid leukemia

,

ovarian epithelial carcinoma

,

,

,

bronchopulmonary dysplasia

,

respiratory syncytial viruses

,

pyoderma gangrenosum

,

spondylarthropathies

,

spinal diseases

,

,

intermediate uveitis

,

posterior uveitis

,

retinal diseases

,

retinal degeneration

,

,

choroidal neovascularization

,

hepatocellular carcinoma

,

liver neoplasms

,

,

rheumatoid arthritis

,

,

,

,

ulcerative colitis

,

psoriatic arthritis

,

ankylosing spondylitis

,

inflammatory bowel diseases

,

,

hidradenitis suppurativa

,

axial spondyloarthritis

,

spondylarthritis

,

cardiovascular diseases

,

connective tissue diseases

,

,

pathologic constriction

,

intestinal diseases

,

,

atopic dermatitis

,

atherosclerosis

,

drug monitoring

,

drug interactions

,

diabetes mellitus

,

,

,

pharmacokinetics

,

,

,

,

,

hereditary angioedemas

,

cytomegalovirus

,

,

human influenza

,

acquired immunodeficiency syndrome

,

substance-related disorders

,

bacterial infections

,

postural orthostatic tachycardia syndrome

,

orthostatic intolerance

,

,

,

,

circulating neoplastic cells

,

,

,

major depressive disorder

,

depressive disorder

,

essential hypertension

,

alzheimer disease

,

huntington disease

,

,

chronic hepatitis b

,

,

,

pulmonary tuberculosis

,

multidrug-resistant tuberculosis

,

latent tuberculosis

,

chronic obstructive pulmonary disease

,

disease progression

,

obstructive lung diseases

,

,

type 2 diabetes mellitus

,

breast neoplasms

,

rheumatoid arthritis

,

,

non-small-cell lung carcinoma

,

pancreatic neoplasms

,

non-alcoholic fatty liver disease

,

,

prostatic neoplasms

,

cystic fibrosis

,

,

,

liver cirrhosis

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

head and neck neoplasms

,

cardiomyopathies

,

dilated cardiomyopathy

,

,

,

,

lymphangiogenesis

,

,

,

alcoholic fatty liver

,

chemical and drug induced liver injury

,

alcoholic hepatitis

,

alcohol-induced disorders

,

systolic heart failure

,

,

newborn infant diseases

,

premature infant diseases

,

univentricular heart

,

medulloblastoma

,

colorectal neoplasms

,

amyotrophic lateral sclerosis

,

,

cardiac arrhythmias

,

supraventricular tachycardia

,

,

cardiovascular diseases

,

sinus arrhythmia

,

healthy volunteers/patients

,

atrial fibrillation

,

,

drug-related side effects and adverse reactions

,

renal insufficiency

,

,

induced abortion

,

congenital heart defects

,

,

pulmonary hypertension

,

bipolar disorder

,

,

breast diseases

,

fibrocystic breast disease

,

thyroid neoplasms

,

papillary thyroid cancer

insulin resistance

,

healthy volunteers/patients

,

prediabetic state

,

,

autonomic nervous system diseases

,

orthostatic intolerance

,

,

,

status asthmaticus

,

glucose intolerance

,

digestive system physiological phenomena

,

gastrointestinal motility

,

,

,

near-infrared spectroscopy

,

,

,

,

vasoconstriction

,

allergic rhinitis

,

orthostatic hypotension

,

nervous system diseases

,

primary dysautonomias

,

,

spinal fractures

,

pharmacokinetics

,

,

breast neoplasms

,

,

,

,

non-small-cell lung carcinoma

,

brain neoplasms

,

colonic neoplasms

,

,

allergic rhinitis seasonal

,

,

alveolar soft part sarcoma

,

hemostatic disorders

,

,

granulosa cell tumor

,

amyotrophic lateral sclerosis

,

,

regional blood flow

,

ocular physiological phenomena

,

parkinson disease

,

,

ventilator-associated pneumonia

,

,

,

pancreatic neoplasms

,

ductal carcinoma

,

,

eye axial length

,

degenerative myopia

,

obstructive lung diseases

,

general anesthesia

,

emergence delirium

,

,

,

,

replacement arthroplasty hip

,

,

,

,

,

anterior uveitis

,

,

,

anesthesia and analgesia

,

,

stomach neoplasms

,

neoplasm metastasis

,

retinal diseases

,

retinopathy of prematurity

,

cerebral infarction

,

replacement arthroplasty knee

,

,

blood coagulation

,

familial dysautonomia

,

vision disorders

,

,

colorectal neoplasms

,

,

squamous cell carcinoma

,

esophageal squamous cell carcinoma

,

,

chronic obstructive pulmonary disease

,

neuromuscular blockade

,

,

,

postoperative pain

,

,

,

,

,

,

postoperative nausea and vomiting

,

delayed emergence from anesthesia

,

drug-related side effects and adverse reactions

,

,

cesarean section

,

organophosphate poisoning

,

,

spinal anesthesia

,

respiratory distress syndrome

,

,

disease progression

,

intratracheal intubation

,

newborn respiratory distress syndrome

,

,

cognitive dysfunction

,

muscle hypotonia

,

post-dural puncture headache

,

cardiac arrhythmias

,

,

,

premature birth

,

,

,

respiratory aspiration

,

,

respiratory insufficiency

,

pulmonary atelectasis

,

,

,

retinal detachment

,

,

alzheimer disease

,

,

,

muscle relaxation

,

obstructive sleep apnea

,

sleep apnea syndromes

,

,

,

,

wounds and injuries

,

hip osteoarthritis

,

refractive errors

,

,

conscious sedation

,

,

signs and symptoms

,

cognition disorders

,

neurocognitive disorders

,

postoperative period

,

anesthesia recovery period

,

,

liver cirrhosis

,

,

newborn infant diseases

,

dental care for persons with disabilities

,

,

,

nephrolithiasis

,

,

lower urinary tract symptoms

,

esophageal achalasia

,

respiratory tract infections

,

cold temperature

,

exercise-induced asthma

,

,

,

bronchiolitis obliterans syndrome

,

,

hepatocellular carcinoma

,

muscle weakness

,

myocardial infarction

,

,

,

inferior wall myocardial infarction

,

pleural effusion

,

,

malignant pleural effusion

,

lymphadenopathy

,

pleural empyema

,

,

,

pericardial effusion

,

pleural diseases

,

pleural neoplasms

,

,

procedural pain

,

cystic fibrosis

,

coronary artery disease

,

,

,

conduction anesthesia

,

renal insufficiency

,

acute kidney injury

,

,

psychomotor agitation

,

,

depressive disorder

,

intravenous anesthesia

,

vascular diseases

,

,

inhalation anesthesia

,

obstetric labor complications

,

,

coronary disease

,

myocardial ischemia

,

angina pectoris

,

vasovagal syncope

,

,

,

diabetic retinopathy

,

,

retinal neovascularization

,

pathologic neovascularization

,

carotid stenosis

,

aortic dissection

,

thoracic surgical procedures

,

cardiac catheterization

,

blood coagulation tests

,

postoperative cognitive complications

,

,

diaphragmatic hernias congenital

,

diaphragmatic hernia

,

hypersensitivity

,

urinary bladder neoplasms

,

cardiovascular diseases

,

sudden death cardiac

,

,

,

,

,

irritable bowel syndrome

,

gastrointestinal diseases

,

,

,

,

stress echocardiography

,

diastolic heart failure

,

interstitial lung diseases

,

respiratory signs and symptoms

,

,

,

acute lung injury

,

,

,

,

,

psychology biofeedback

,

,

,

,

prosthesis failure

,

,

,

polymorphic catecholaminergic ventricular tachycardia

,

postural orthostatic tachycardia syndrome

,

,

,

,

gastric outlet obstruction

,

oculocardiac reflex

,

,

airway remodeling

,

airway obstruction

,

,

microvascular angina

,

variant angina pectoris

,

thoracic diseases

,

local anesthesia

,

postoperative complications

,

inguinal hernia

,

,

,

systolic murmurs

,

atrioventricular block

,

major depressive disorder

,

sick sinus syndrome

,

supraventricular tachycardia

,

,

pregnancy complications

,

myasthenia gravis

,

aortic aneurysm

,

ophthalmologic surgical procedures

,

bariatric surgery

,

,

atrial fibrillation

,

,

urinary retention

,

,

,

,

communicable diseases

,

unconsciousness

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