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Company ReportsPuma Biotechnology
Puma Biotechnology(PBYI)
Puma Biotechnology is a publicly traded biopharmaceutical company (NASDAQ: PBYI) headquartered in Los Angeles, CA.
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Trade Name
Drug Name
Approved
Patent Expires
Indication
NerlynxNeratinib2017-07-172025-2031
Breast neoplasms
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Neratinib
healthy volunteers/patients
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
hematologic neoplasms
,
myeloproliferative disorders
,
non-hodgkin lymphoma
,
primary myelofibrosis
,
multiple myeloma
,
precursor cell lymphoblastic leukemia-lymphoma
,
b-cell chronic lymphocytic leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
myelomonocytic leukemia chronic
,
anemia
,
hodgkin disease
,
leukemia myeloid chronic atypical bcr-abl negative
,
myelodysplastic-myeloproliferative diseases
,
myeloid leukemia chronic-phase
,
myeloid leukemia accelerated phase
,
blast crisis
,
thrombocytosis
,
erbb-2 genes
,
erbb genes
,
liver failure
,
hepatic insufficiency
,
gastrointestinal neoplasms
,
esophageal squamous cell carcinoma
,
neoplasms
,
neoplasm metastasis
,
triple negative breast neoplasms
,
brain neoplasms
,
stomach neoplasms
,
pancreatic neoplasms
,
non-small-cell lung carcinoma
,
adenocarcinoma
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
diarrhea
,
colorectal neoplasms
,
lung neoplasms
,
ovarian neoplasms
,
inflammatory breast neoplasms
,
neurofibromatosis 2
,
acoustic neuroma
,
meningioma
,
ependymoma
,
hemangiosarcoma
,
pathologic complete response
,
hereditary sensory and autonomic neuropathies
,
colonic neoplasms
,
disease progression
,
glioblastoma
,
leukemia
,
lymphoma
,
central nervous system neoplasms
,
disease
,
endometrial neoplasms
,
fallopian tube neoplasms
,
lobular carcinoma
,
invasive hydatidiform mole
,
carcinoma
,
pancreatic ductal carcinoma
,
myoepithelioma
,
radiotherapy
,
adenosquamous carcinoma
,
breast neoplasms
,
recurrence
,
biliary tract neoplasms
,
uterine cervical neoplasms
,
urinary bladder neoplasms
,
neoadjuvant therapy
Benzimidazole
neoplasms
,
melanoma
,
healthy volunteers/patients
Aglatimagene besadenovec
leiomyoma
,
myofibroma
,
head and neck neoplasms
,
esophageal neoplasms
,
disease progression
,
merkel cell carcinoma
,
neuroendocrine carcinoma
,
papillary thyroid cancer
,
medullary carcinoma
,
disease
,
castration-resistant prostatic neoplasms
,
adenocarcinoma
,
large b-cell lymphoma diffuse
,
urogenital neoplasms
,
male genital neoplasms
,
lymphoma
,
small cell lung carcinoma
,
b-cell lymphoma
,
renal cell carcinoma
,
male genital diseases
,
prostatic diseases
,
abdominal neoplasms
,
genital diseases
,
leukemia
,
myelomonocytic leukemia chronic
,
systemic mastocytosis
,
myelomonocytic leukemia juvenile
,
hypereosinophilic syndrome
,
mastocytosis
,
dermatofibrosarcoma
,
hematologic neoplasms
,
sarcoma
,
neuroendocrine tumors
,
carcinoma
,
renal insufficiency
,
urologic neoplasms
,
kidney neoplasms
,
endometrial neoplasms
,
non-hodgkin lymphoma
,
immune system diseases
,
t-cell lymphoma
,
lymphoproliferative disorders
,
malignant mesothelioma
,
neoplasms by histologic type
,
neoplasms by site
,
lymphatic diseases
,
immunoproliferative disorders
,
anemia
,
thrombocytopenia
,
pancytopenia
,
cytopenia
,
x-linked bulbo-spinal atrophy
,
neoplasms
,
osteoporosis
,
lung neoplasms
,
pain
,
recurrence
,
bone resorption
,
hypercalcemia
,
prostatic neoplasms
,
neoplasm metastasis
,
breast neoplasms
,
bone neoplasms
,
bone marrow diseases
,
multiple myeloma
,
second primary neoplasms
,
plasma cell neoplasms
,
hypersensitivity
,
plasmacytoma
,
osteonecrosis
Alisertib
pancreatic ductal carcinoma
,
pancreatic neoplasms
,
neoplasms
,
acinar cell carcinoma
,
myeloid leukemia acute
Edrecolomab
neoplasm metastasis
,
non-small-cell lung carcinoma
,
urologic neoplasms
,
urinary bladder neoplasms
,
ureteral neoplasms
,
triple negative breast neoplasms
,
prostatic neoplasms
,
ovarian neoplasms
,
pancreatic neoplasms
,
esophageal neoplasms
,
squamous cell carcinoma of head and neck
,
uterine cervical neoplasms
,
pelvic neoplasms
,
non-muscle invasive bladder neoplasms
,
lung neoplasms
,
adenocarcinoma
,
squamous cell carcinoma
,
endometrial neoplasms
,
small cell lung carcinoma
,
obesity
,
overweight
,
healthy volunteers/patients
,
neoplasms
,
multiple myeloma
,
plasma cell neoplasms
,
brain neoplasms
,
glioblastoma
,
neuroblastoma
,
glioma
,
osteosarcoma
,
medulloblastoma
,
rhabdoid tumor
,
ependymoma
,
ewing sarcoma
,
rhabdomyosarcoma
,
diffuse intrinsic pontine glioma
,
hearing loss
,
sensorineural hearing loss
,
bilateral hearing loss
,
deafness
Lornoxicam
neoplasms
,
lymphoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
multiple myeloma
,
hodgkin disease
,
mantle-cell lymphoma
,
renal cell carcinoma
,
t-cell leukemia
,
b-cell leukemia
,
plasma cell neoplasms
,
diffuse scleroderma
,
myositis
,
dermatomyositis
,
interstitial lung diseases
,
breast neoplasms
,
non-hodgkin lymphoma
,
leukemia
,
lymphoid leukemia
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
sarcoma
,
non-small-cell lung carcinoma
,
neoplasm metastasis
,
osteosarcoma
,
b-cell chronic lymphocytic leukemia
,
osteoporosis
,
cerebrotendinous xanthomatosis
,
recurrence
,
follicular lymphoma
,
kidney diseases
Aspartame
fibrosis
,
gastrointestinal diseases
,
cystic fibrosis
,
digestive system diseases
,
pancreatic diseases
,
exocrine pancreatic insufficiency
Bevifimod
hematologic neoplasms
,
biphenotypic leukemia acute
,
b-cell leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
stomach neoplasms
,
myelodysplastic syndromes
,
stroke
,
muscle spasticity
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
endometriosis
,
infertility
,
pancreatic ductal carcinoma
,
biliary tract neoplasms
,
esophageal squamous cell carcinoma
,
ovarian neoplasms
,
recurrence
,
b-cell lymphoma
,
b-cell lymphoma marginal zone
,
fallopian tube neoplasms
,
burkitt lymphoma
,
triple negative breast neoplasms
,
squamous cell carcinoma of head and neck
,
multiple myeloma
,
prostatic neoplasms
,
pancreatic neoplasms
,
esophageal neoplasms
,
breast neoplasms
,
reactive arthritis
,
waldenstrom macroglobulinemia
,
lymphoproliferative disorders
,
lymphatic diseases
,
intestinal neoplasms
,
colonic neoplasms
,
rectal neoplasms
,
carcinoma
,
glioblastoma
,
melanoma
,
neuroendocrine carcinoma
,
papillary thyroid cancer
,
adenocarcinoma
,
primary myelofibrosis
,
splenomegaly
,
hairy cell leukemia
,
abdominal hernia
,
ventral hernia
,
urinary bladder neoplasms
,
uterine neoplasms
,
knee osteoarthritis
,
residual neoplasm
,
neuralgia
,
interstitial cystitis
,
neoadjuvant therapy
,
ovarian epithelial carcinoma
,
mantle-cell lymphoma
,
female genital neoplasms
,
peritoneal neoplasms
,
fallopian tube diseases
,
neoplasms
,
non-hodgkin lymphoma
,
crohn disease
,
non-small-cell lung carcinoma
,
b-cell chronic lymphocytic leukemia
,
myeloid leukemia acute
,
colorectal neoplasms
,
lymphoma
,
large b-cell lymphoma diffuse
,
follicular lymphoma
,
lung neoplasms
,
joint diseases
,
musculoskeletal diseases
,
ankylosing spondylitis
,
small cell lung carcinoma
,
macular degeneration
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
inflammatory bowel diseases
,
spondylitis
,
juvenile arthritis
,
neoplasm metastasis
,
skin diseases
,
papulosquamous skin diseases
,
wet macular degeneration
,
hepatocellular carcinoma
,
liver neoplasms
,
infections
,
communicable diseases
,
bacterial infections
,
methicillin-resistant staphylococcus aureus
,
staphylococcal skin infections
,
infectious skin diseases
,
bacterial skin diseases
,
cellulitis
,
disease progression
,
covid-19
,
parkinson disease
,
bronchopulmonary dysplasia
,
respiratory syncytial viruses
,
hepatitis b
,
ulcer
,
pyoderma gangrenosum
,
spondylarthropathies
,
spondylarthritis
,
spinal diseases
,
uveitis
,
intermediate uveitis
,
posterior uveitis
,
precocious puberty
,
migraine disorders
,
retinal diseases
,
retinal degeneration
,
eye diseases
,
choroidal neovascularization
,
leukemia
,
lymphoid leukemia
,
thyroid diseases
,
hypothyroidism
,
rheumatoid arthritis
,
psoriasis
,
arthritis
,
ulcerative colitis
,
psoriatic arthritis
,
hidradenitis suppurativa
,
hepatitis c
,
chronic hepatitis c
,
axial spondyloarthritis
,
cardiovascular diseases
,
connective tissue diseases
,
seizures
,
panuveitis
,
hiv infections
,
drug monitoring
,
coronary artery disease
,
myocardial ischemia
,
inflammation
,
atherosclerosis
,
hyperhidrosis
Nepidermin
breast neoplasms
,
carcinoma
,
head and neck neoplasms
,
squamous cell carcinoma of head and neck
,
non-small-cell lung carcinoma
,
neoplasm metastasis
,
myofascial pain syndromes
,
fibromyalgia
,
syndrome
,
hemangioma
,
port-wine stain
,
capillary hemangioma
,
urinary bladder neoplasms
,
transitional cell carcinoma
,
melanoma
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
healthy volunteers/patients
Polyglycolic acid
sezary syndrome
,
mycosis fungoides
,
t-cell lymphoma cutaneous
,
mucositis
,
primary cutaneous anaplastic large cell lymphoma
,
non-small-cell lung carcinoma
,
lung neoplasms
,
recurrence
,
lymphoma
,
t-cell lymphoma peripheral
,
t-cell lymphoma
,
neoplasm metastasis
,
non-hodgkin lymphoma
,
breast neoplasms
,
carcinoma
,
urinary bladder neoplasms
,
transitional cell carcinoma
,
leukemia
,
extranodal nk-t-cell lymphoma
,
hodgkin disease
,
waldenstrom macroglobulinemia
,
b-cell lymphoma
,
large-cell lymphoma anaplastic
,
immunoblastic lymphadenopathy
Globulin, immune
myeloid leukemia acute
,
guillain-barre syndrome
,
multiple sclerosis
,
neuromyelitis optica
,
optic neuritis
,
myasthenia gravis
,
chronic inflammatory demyelinating polyradiculoneuropathy
Digitalis
atrial fibrillation
,
cardiac arrhythmias
Hyoscyamine
chronic obstructive pulmonary disease
,
respiratory insufficiency
Anthracycline
neoplasms
,
neoplasms by histologic type
,
connective and soft tissue neoplasms
,
breast neoplasms
,
ovarian neoplasms
,
ovarian epithelial carcinoma
,
myeloid leukemia acute
,
plasmablastic lymphoma
,
leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
lymphoma
,
multiple myeloma
,
plasma cell neoplasms
,
b-cell lymphoma
,
leiomyosarcoma
,
non-hodgkin lymphoma
,
sarcoma
,
liposarcoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma marginal zone
,
follicular lymphoma
,
mantle-cell lymphoma
,
carcinoma
,
hepatocellular carcinoma
,
liver neoplasms
,
circulating neoplastic cells
Endocrine
healthy volunteers/patients
,
ovarian neoplasms
,
triple negative breast neoplasms
,
castration-resistant prostatic neoplasms
,
non-small-cell lung carcinoma
,
liposarcoma
,
colorectal neoplasms
,
adenocarcinoma of lung
,
lobular carcinoma
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
neoplasms
,
type 2 diabetes mellitus
,
prostatic neoplasms
,
endocrine system diseases
,
diabetes mellitus
,
male breast neoplasms
,
recurrence
,
unilateral breast neoplasms
,
obesity
,
glucose metabolism disorders
,
metabolic diseases
,
body weight
,
overweight
,
nutrition disorders
,
signs and symptoms
,
nutritional and metabolic diseases
,
signs and symptoms pathological conditions
,
overnutrition
,
neoplasm metastasis
,
breast neoplasms
,
acromegaly
,
laron syndrome
,
pituitary dwarfism
,
left ventricular hypertrophy
,
left ventricular dysfunction
,
bipolar disorder
,
coronary disease
,
coronary artery disease
,
chronic disease
,
traumatic brain injuries
,
brain concussion
,
hypopituitarism
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