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Puma Biotechnology
Puma Biotechnology
(PBYI)
Puma Biotechnology is a publicly traded biopharmaceutical company (NASDAQ: PBYI) headquartered in Los Angeles, CA.
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Nerlynx
Neratinib
2017-07-17
2025-2031
Breast neoplasms
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Neratinib
healthy volunteers/patients
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
hematologic neoplasms
,
pancreatic neoplasms
,
myeloproliferative disorders
,
non-hodgkin lymphoma
,
primary myelofibrosis
,
multiple myeloma
,
precursor cell lymphoblastic leukemia-lymphoma
,
b-cell chronic lymphocytic leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
myelomonocytic leukemia chronic
,
anemia
,
hodgkin disease
,
leukemia myeloid chronic atypical bcr-abl negative
,
myelodysplastic-myeloproliferative diseases
,
myeloid leukemia chronic-phase
,
myeloid leukemia accelerated phase
,
blast crisis
,
thrombocytosis
,
erbb-2 genes
,
erbb genes
,
ovarian epithelial carcinoma
,
liver failure
,
hepatic insufficiency
,
gastrointestinal neoplasms
,
esophageal squamous cell carcinoma
,
neoplasms
,
neoplasm metastasis
,
triple negative breast neoplasms
,
brain neoplasms
,
stomach neoplasms
,
non-small-cell lung carcinoma
,
adenocarcinoma
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
diarrhea
,
colorectal neoplasms
,
lung neoplasms
,
ovarian neoplasms
,
inflammatory breast neoplasms
,
neurofibromatosis 2
,
acoustic neuroma
,
meningioma
,
ependymoma
,
neurofibromatosis 1
,
neurofibromatoses
,
neurofibroma
,
neurilemmoma
,
hemangiosarcoma
,
hereditary sensory and autonomic neuropathies
,
carcinoma
,
glioblastoma
,
leukemia
,
lymphoma
,
central nervous system neoplasms
,
disease
,
endometrial neoplasms
,
fallopian tube neoplasms
,
lobular carcinoma
,
invasive hydatidiform mole
,
pancreatic ductal carcinoma
,
ductal carcinoma
,
myoepithelioma
,
radiotherapy
,
adenosquamous carcinoma
,
breast neoplasms
,
recurrence
,
biliary tract neoplasms
,
uterine cervical neoplasms
,
urinary bladder neoplasms
,
neoadjuvant therapy
Benzimidazole
non-hodgkin lymphoma
,
ulcerative colitis
,
crohn disease
,
colitis
,
ulcer
,
psoriasis
,
rheumatoid arthritis
,
arthritis
,
pharmacokinetics
,
neoplasms
,
multiple myeloma
,
plasma cell neoplasms
,
glioblastoma
,
glioma
,
gliosarcoma
,
astrocytoma
,
diffuse intrinsic pontine glioma
,
optic nerve glioma
,
brain stem neoplasms
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
syndrome
,
healthy volunteers/patients
,
lymphoma
,
peptic esophagitis
,
peripheral arterial disease
,
b-cell lymphoma marginal zone
,
follicular lymphoma
,
mantle-cell lymphoma
,
leukemia
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
infections
,
communicable diseases
,
helminthiasis
,
vomiting
,
gastroenteritis
,
heartburn
,
non-erosive reflux disease
,
asthma
,
gastroesophageal reflux
,
sleep initiation and maintenance disorders
,
sleep wake disorders
,
parasomnias
,
atrial fibrillation
,
venous thromboembolism
,
thromboembolism
,
stroke
,
schizophrenia
,
sudden death cardiac
,
death
,
sudden death
Aglatimagene besadenovec
prostatic hyperplasia
,
hyperplasia
,
lower urinary tract symptoms
Alisertib
pancreatic ductal carcinoma
,
pancreatic neoplasms
,
neoplasms
,
acinar cell carcinoma
,
myeloid leukemia acute
Edrecolomab
anemia
,
anxiety disorders
,
depressive disorder
,
heart failure
,
hepatitis b
,
hepatitis
,
hepatitis a
,
multiple myeloma
,
plasma cell neoplasms
,
chronic hepatitis b
,
human influenza
,
chronic hepatitis
,
infections
,
urinary tract infections
,
restless legs syndrome
,
psychomotor agitation
,
syndrome
Lornoxicam
multiple myeloma
,
plasma cell neoplasms
Aspartame
leukemia
,
neoplasms
,
atopic dermatitis
,
myeloid leukemia acute
,
multiple myeloma
,
lymphoma
,
plasma cell neoplasms
,
large b-cell lymphoma diffuse
,
type 2 diabetes mellitus
,
diabetes mellitus
,
recurrence
,
opioid-related disorders
,
alzheimer disease
,
huntington disease
,
eczema
,
dermatitis
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
covid-19
,
meningioma
,
inflammation
,
triple negative breast neoplasms
,
serogroup b neisseria meningitidis
,
crush injuries
,
urologic neoplasms
,
urinary bladder neoplasms
,
urologic diseases
,
urinary bladder diseases
,
down syndrome
,
syndrome
,
cognitive dysfunction
,
central nervous system neoplasms
,
solitary fibrous tumors
,
neurofibromatosis 1
,
neurofibromatoses
,
hemangioblastoma
,
hemangiopericytoma
,
neurofibroma
,
streptococcal infections
,
thyroid neoplasms
,
thyroid diseases
,
pain
,
breast neoplasms
,
sickle cell anemia
,
pneumonia
,
renal insufficiency
,
headache
,
tension-type headache
,
toothache
,
meningitis
,
rheumatoid arthritis
,
arthritis
,
bacterial pneumonia
,
juvenile arthritis
,
psoriatic arthritis
,
ankylosing spondylitis
,
carotid artery diseases
,
atherosclerosis
,
ulcerative colitis
,
meningococcal meningitis
,
stroke
,
thromboembolism
,
hiv infections
,
tuberculosis
,
acquired immunodeficiency syndrome
,
immune reconstitution inflammatory syndrome
,
seizures
,
alopecia areata
,
alopecia
,
hair diseases
,
healthy volunteers/patients
,
infections
,
communicable diseases
,
intraabdominal infections
,
smoking cessation
,
neuroendocrine tumors
,
islet cell adenoma
,
psychomotor agitation
,
schizophrenia
,
renal cell carcinoma
,
carcinoma
,
gaucher disease
,
tobacco use disorder
,
acromegaly
,
fatigue
Bevifimod
complex regional pain syndromes
,
pelvic pain
,
dyspareunia
,
vaginismus
,
psoriasis
,
chronic pain
,
stress urinary incontinence
,
osteoarthritis
,
prostatic hyperplasia
,
choroidal neovascularization
,
neuralgia
,
diabetes mellitus
,
magnetic resonance imaging
,
therapeutics
,
joint diseases
,
hypertrophic cicatrix
,
pruritus
,
major depressive disorder
,
carpal tunnel syndrome
,
premature ejaculation
,
hyperalgesia
,
rectal neoplasms
,
low anterior resection syndrome
,
cicatrix
,
penile induration
,
thoracic outlet syndrome
,
postherpetic neuralgia
,
motor neuron disease
,
thyroid diseases
,
hypothyroidism
,
ovarian neoplasms
,
stomach neoplasms
,
head and neck neoplasms
,
esophageal neoplasms
,
lung neoplasms
,
urinary bladder neoplasms
,
small cell lung carcinoma
,
endophthalmitis
,
lacrimal apparatus diseases
,
lacerations
,
radiation injuries
,
uveal neoplasms
,
uveal melanoma
,
pancreatic neoplasms
,
macular degeneration
,
cerebral palsy
,
breast neoplasms
,
myofascial pain syndromes
,
neurogenic urinary bladder
,
shoulder pain
,
prostatitis
,
arthritis
,
arthralgia
,
non-small-cell lung carcinoma
,
dystonic disorders
,
temporomandibular joint disorders
,
facial pain
,
acrodynia
,
somatoform disorders
,
systemic scleroderma
,
raynaud disease
,
diffuse scleroderma
,
urinary bladder diseases
,
multiple sclerosis
,
neoplasms
,
postoperative pain
,
breast diseases
,
hereditary breast and ovarian cancer syndrome
,
sialorrhea
,
paresis
,
knee injuries
,
patellofemoral pain syndrome
,
allergic conjunctivitis
,
constipation
,
muscle spasticity
,
overactive urinary bladder
,
urinary incontinence
,
migraine disorders
,
stroke
,
macular edema
,
torticollis
,
healthy volunteers/patients
,
headache
,
hyperhidrosis
,
dry eye syndromes
,
pain
,
prostatic neoplasms
,
diabetic retinopathy
,
parkinson disease
,
brain injuries
,
skin aging
,
dystonia
,
blepharospasm
,
chronic kidney failure
,
renal insufficiency
,
iron-deficiency anemia
,
iron deficiencies
,
aging
,
interstitial cystitis
,
graves ophthalmopathy
,
depression
,
bruxism
,
spinal cord injuries
,
developmental disabilities
,
hirsutism
,
hypertension
,
left ventricular hypertrophy
,
blood pressure
,
sjogren's syndrome
,
retinal vein occlusion
,
herpes labialis
,
traumatic brain injuries
,
strabismus
,
neck pain
,
back pain
,
keratoconjunctivitis sicca
,
dysphonia
,
glaucoma
,
muscle strength
,
clostridium botulinum type a
Nepidermin
macular degeneration
Polyglycolic acid
carcinoma
,
hepatocellular carcinoma
,
liver neoplasms
,
pancreatic neoplasms
Globulin, immune
healthy volunteers/patients
,
neoplasms
,
colonic neoplasms
,
adenocarcinoma
,
systemic lupus erythematosus
,
colorectal neoplasms
,
kidney diseases
,
iga glomerulonephritis
,
ovarian neoplasms
,
ovarian epithelial carcinoma
,
ascites
,
agammaglobulinemia
,
alzheimer disease
,
chronic inflammatory demyelinating polyradiculoneuropathy
,
polyradiculoneuropathy
,
thrombocytopenic purpura idiopathic
,
dementia
,
mucocutaneous lymph node syndrome
,
primary immunodeficiency diseases
,
immunologic deficiency syndromes
Digitalis
neoplasms
,
melanoma
,
healthy volunteers/patients
Hyoscyamine
chronic obstructive pulmonary disease
,
respiratory signs and symptoms
,
motor activity
,
exercise
Anthracycline
myelodysplastic syndromes
,
precursor cell lymphoblastic leukemia-lymphoma
,
neoplasm metastasis
,
myeloproliferative disorders
,
myelodysplastic-myeloproliferative diseases
,
myeloid leukemia acute
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
leukemia
,
myeloid leukemia
,
recurrence
,
biphenotypic leukemia acute
,
b-cell chronic lymphocytic leukemia
,
hairy cell leukemia
,
b-cell lymphoma marginal zone
,
reactive arthritis
,
t-cell lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
burkitt lymphoma
,
non-hodgkin lymphoma
,
lymphoma
,
neoplasms
,
follicular lymphoma
,
breast neoplasms
,
triple negative breast neoplasms
Endocrine
hypogonadism
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