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Company ReportsPuma Biotechnology
Puma Biotechnology(PBYI)
Puma Biotechnology is a publicly traded biopharmaceutical company (NASDAQ: PBYI) headquartered in Los Angeles, CA.
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Trade Name
Drug Name
Approved
Patent Expires
Indication
NerlynxNeratinib2017-07-172025-2031
Breast neoplasms
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Neratinib
healthy volunteers/patients
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
hematologic neoplasms
,
myeloproliferative disorders
,
non-hodgkin lymphoma
,
primary myelofibrosis
,
multiple myeloma
,
precursor cell lymphoblastic leukemia-lymphoma
,
b-cell chronic lymphocytic leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
myelomonocytic leukemia chronic
,
anemia
,
hodgkin disease
,
leukemia myeloid chronic atypical bcr-abl negative
,
myelodysplastic-myeloproliferative diseases
,
myeloid leukemia chronic-phase
,
myeloid leukemia accelerated phase
,
blast crisis
,
thrombocytosis
,
erbb-2 genes
,
erbb genes
,
liver failure
,
hepatic insufficiency
,
gastrointestinal neoplasms
,
esophageal squamous cell carcinoma
,
neoplasms
,
neoplasm metastasis
,
triple negative breast neoplasms
,
brain neoplasms
,
stomach neoplasms
,
non-small-cell lung carcinoma
,
adenocarcinoma
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
pancreatic neoplasms
,
diarrhea
,
colorectal neoplasms
,
lung neoplasms
,
ovarian neoplasms
,
inflammatory breast neoplasms
,
neurofibromatosis 2
,
acoustic neuroma
,
meningioma
,
ependymoma
,
hemangiosarcoma
,
pathologic complete response
,
hereditary sensory and autonomic neuropathies
,
colonic neoplasms
,
disease progression
,
glioblastoma
,
leukemia
,
lymphoma
,
central nervous system neoplasms
,
disease
,
endometrial neoplasms
,
fallopian tube neoplasms
,
lobular carcinoma
,
invasive hydatidiform mole
,
carcinoma
,
pancreatic ductal carcinoma
,
myoepithelioma
,
radiotherapy
,
adenosquamous carcinoma
,
breast neoplasms
,
recurrence
,
biliary tract neoplasms
,
uterine cervical neoplasms
,
urinary bladder neoplasms
,
neoadjuvant therapy
Benzimidazole
healthy volunteers/patients
Aglatimagene besadenovec
breast neoplasms
,
ovarian neoplasms
,
ovarian epithelial carcinoma
,
neoplasms
,
lung neoplasms
,
glioblastoma
,
small cell lung carcinoma
,
neuroendocrine carcinoma
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
adenocarcinoma
,
head and neck neoplasms
,
esophageal neoplasms
,
gastrointestinal neoplasms
,
sarcoma
,
urogenital neoplasms
,
skin neoplasms
,
melanoma
,
colonic neoplasms
,
healthy volunteers/patients
Alisertib
head and neck neoplasms
,
gastrointestinal neoplasms
,
digestive system neoplasms
,
pancreatic neoplasms
,
b-cell chronic lymphocytic leukemia
,
laryngeal diseases
,
colorectal neoplasms
,
mucinous adenocarcinoma
,
colonic neoplasms
,
rectal neoplasms
,
cystadenocarcinoma
,
urogenital neoplasms
,
central nervous system neoplasms
,
thoracic neoplasms
,
mycoses
,
sezary syndrome
,
mycosis fungoides
,
hairy cell leukemia
,
intraocular lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
plasmablastic lymphoma
,
large granular lymphocytic leukemia
,
large-cell lymphoma immunoblastic
,
lymphomatoid granulomatosis
,
lymphoid leukemia
,
hematologic neoplasms
,
enteropathy-associated t-cell lymphoma
,
female genital neoplasms
,
lip neoplasms
,
male genital neoplasms
,
papilloma
,
triple negative breast neoplasms
,
brain neoplasms
,
glioblastoma
,
glioma
,
gliosarcoma
,
ependymoma
,
astrocytoma
,
oligodendroglioma
,
pancreatic ductal carcinoma
,
acinar cell carcinoma
,
neoplasms
,
lymphoma
,
breast neoplasms
,
recurrence
,
mantle-cell lymphoma
,
b-cell lymphoma
,
follicular lymphoma
,
large b-cell lymphoma diffuse
,
burkitt lymphoma
,
non-hodgkin lymphoma
,
adenocarcinoma
,
lung neoplasms
,
leukemia
,
t-cell lymphoma
,
prostatic neoplasms
,
small cell lung carcinoma
,
myeloid leukemia acute
,
non-small-cell lung carcinoma
,
neuroblastoma
,
ovarian neoplasms
,
hodgkin disease
,
b-cell lymphoma marginal zone
,
waldenstrom macroglobulinemia
,
large-cell lymphoma anaplastic
,
immunoblastic lymphadenopathy
,
multiple myeloma
,
melanoma
,
carcinoma
,
squamous cell carcinoma of head and neck
,
precursor cell lymphoblastic leukemia-lymphoma
,
adult t-cell leukemia-lymphoma
,
t-cell lymphoma cutaneous
,
t-cell leukemia
,
myeloid leukemia
,
sarcoma
,
leiomyosarcoma
,
plasma cell neoplasms
,
invasive hydatidiform mole
,
postmenopause
,
rhabdoid tumor
,
phenylketonurias
,
squamous cell carcinoma
,
urinary bladder neoplasms
,
transitional cell carcinoma
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
peritoneal neoplasms
,
malignant mesothelioma
,
mesothelioma
,
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
fibrosarcoma
,
liposarcoma
,
neurofibrosarcoma
,
malignant fibrous histiocytoma
,
nerve sheath neoplasms
,
extranodal nk-t-cell lymphoma
,
osteosarcoma
,
kidney neoplasms
,
ewing sarcoma
,
rhabdomyosarcoma
,
primitive neuroectodermal tumors
,
primitive neuroectodermal tumors peripheral
,
hepatoblastoma
,
embryonal rhabdomyosarcoma
,
neuroectodermal tumors
,
t-cell lymphoma peripheral
,
primary myelofibrosis
,
megakaryoblastic leukemia acute
Edrecolomab
analgesia
,
anesthesia
,
local anesthesia
Lornoxicam
neoplasms
,
lymphoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
multiple myeloma
,
plasma cell neoplasms
,
hodgkin disease
,
mantle-cell lymphoma
,
renal cell carcinoma
,
t-cell leukemia
,
b-cell leukemia
,
diffuse scleroderma
,
myositis
,
dermatomyositis
,
interstitial lung diseases
,
breast neoplasms
,
non-hodgkin lymphoma
,
leukemia
,
lymphoid leukemia
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
sarcoma
,
non-small-cell lung carcinoma
,
neoplasm metastasis
,
osteosarcoma
,
b-cell chronic lymphocytic leukemia
,
osteoporosis
,
cerebrotendinous xanthomatosis
,
recurrence
,
follicular lymphoma
,
kidney diseases
Aspartame
onychomycosis
,
prurigo
,
neurodermatitis
,
psoriasis
Bevifimod
head and neck neoplasms
,
stroke
,
atherosclerosis
,
intracranial arteriosclerosis
,
fallopian tube neoplasms
,
neoplasms
,
squamous cell carcinoma of head and neck
,
adenocarcinoma
,
prostatic neoplasms
,
renal cell carcinoma
,
triple negative breast neoplasms
,
basal cell carcinoma
,
neoplasm metastasis
,
basal cell neoplasms
,
ovarian epithelial carcinoma
,
colorectal neoplasms
,
pancreatic neoplasms
,
hypersensitivity
,
peanut hypersensitivity
,
allergic rhinitis
,
rhinitis
,
chronic disease
,
healthy volunteers/patients
,
squamous cell carcinoma
,
merkel cell carcinoma
,
lung diseases
,
adenocarcinoma of lung
,
food hypersensitivity
,
milk hypersensitivity
,
smoldering multiple myeloma
,
monoclonal gammopathy of undetermined significance
,
obesity
,
hearing loss
,
hearing disorders
,
sensorineural hearing loss
,
bronchogenic carcinoma
,
bronchial neoplasms
,
paroxysmal hemoglobinuria
,
colonic neoplasms
,
malignant mesothelioma
,
mesothelioma
,
chronic renal insufficiency
,
diabetic nephropathies
,
carcinoma
,
rectal neoplasms
,
non-alcoholic fatty liver disease
,
non-small-cell lung carcinoma
,
ovarian neoplasms
,
melanoma
,
lung neoplasms
,
retinal diseases
,
follicular lymphoma
,
diabetic retinopathy
,
hemorrhage
,
b-cell lymphoma
,
rheumatoid arthritis
,
ascites
,
recurrence
,
type 2 diabetes mellitus
,
multiple myeloma
,
heterotopic ossification
,
myositis ossificans
,
vitreous hemorrhage
,
hodgkin disease
,
large b-cell lymphoma diffuse
,
vision disorders
,
eye diseases
,
blindness
,
hyperlipidemias
,
diabetes mellitus
,
b-cell lymphoma marginal zone
,
non-hodgkin lymphoma
,
macular degeneration
,
protein-losing enteropathies
,
nasal polyps
,
asthma
,
macular edema
,
hemophilia b
Nepidermin
urologic neoplasms
,
glioblastoma
,
glioma
,
astrocytoma
,
plasma cell neoplasms
,
plasmacytoma
,
neoplasms
,
respiratory tract diseases
,
pleural effusion
,
lung diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
thoracic neoplasms
,
neoplasms by site
,
malignant pleural effusion
,
pleural diseases
,
pleural neoplasms
,
squamous cell carcinoma of head and neck
,
recurrence
,
cutaneous malignant melanoma
,
stomach neoplasms
,
ovarian neoplasms
,
kidney transplantation
,
graft rejection
,
psychology rejection
,
male breast neoplasms
,
uveal neoplasms
,
uveal melanoma
,
hodgkin disease
,
pancreatic ductal carcinoma
,
serous cystadenocarcinoma
,
ovarian epithelial carcinoma
,
carcinosarcoma
,
adenocarcinoma of lung
,
bronchiolo-alveolar adenocarcinoma
,
fallopian tube neoplasms
,
peritoneal neoplasms
,
endometrial neoplasms
,
merkel cell carcinoma
,
head and neck neoplasms
,
triple negative breast neoplasms
,
medulloblastoma
,
ependymoma
,
diffuse intrinsic pontine glioma
,
melanoma
,
type 2 diabetes mellitus
,
breast neoplasms
,
non-small-cell lung carcinoma
,
diabetes mellitus
,
lung neoplasms
,
neoplasm metastasis
,
rheumatoid arthritis
,
carcinoma
,
colorectal neoplasms
,
multiple myeloma
,
hepatitis
,
hepatitis c
,
liver neoplasms
,
hiv infections
,
hepatocellular carcinoma
,
transitional cell carcinoma
,
leukemia
,
lymphoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
myeloid leukemia chronic-phase
,
hepatitis b
,
chronic hepatitis b
,
chronic hepatitis
,
hepatitis a
,
hepacivirus
,
juvenile arthritis
,
esophageal neoplasms
,
wasting syndrome
,
cachexia
,
anorexia
,
urinary bladder neoplasms
,
adenocarcinoma
,
rectal neoplasms
,
cardiovascular diseases
,
lymphoid leukemia
,
acute coronary syndrome
,
syndrome
,
atrial fibrillation
,
bcr-abl positive chronic myelogenous leukemia
,
myeloid leukemia accelerated phase
,
lupus nephritis
,
systemic lupus erythematosus
,
giant cell arteritis
,
glucose metabolism disorders
,
metabolic diseases
,
endocrine system diseases
,
body weight
,
exanthema
,
colonic neoplasms
,
hypertension
,
hyperglycemia
,
brain neoplasms
,
heart failure
,
bipolar disorder
,
sjogren's syndrome
,
prostatic neoplasms
,
hematologic neoplasms
,
primary myelofibrosis
Polyglycolic acid
arthritis
,
psoriasis
,
chronic kidney failure
,
renal insufficiency
,
breast feeding
Globulin, immune
pancreatic neoplasms
,
neoplasm metastasis
,
ovarian neoplasms
,
aplastic anemia
,
healthy volunteers/patients
,
chronic kidney failure
,
pancreatic ductal carcinoma
,
non-small-cell lung carcinoma
,
neoplasms
,
urethral neoplasms
,
pelvic neoplasms
,
breast neoplasms
,
squamous cell carcinoma of head and neck
,
urologic neoplasms
,
transitional cell carcinoma
,
non-hodgkin lymphoma
,
adenocarcinoma
,
prostatic neoplasms
,
colorectal neoplasms
,
focal segmental glomerulosclerosis
,
germ cell and embryonal neoplasms
,
psoriatic arthritis
,
kidney diseases
,
stomach neoplasms
,
macular edema
,
recurrence
,
graft vs host disease
,
hepatitis c
,
hepatitis
,
hepatitis a
,
carcinoma
,
liver diseases
,
virus diseases
,
epstein-barr virus infections
,
hepatocellular carcinoma
,
liver neoplasms
,
endometrial neoplasms
,
arthritis
,
liver transplantation
,
urinary bladder neoplasms
,
ureteral neoplasms
,
inflammation
,
encephalitis
,
organ transplantation
,
kidney transplantation
,
psoriasis
,
rheumatoid arthritis
,
diabetes mellitus
,
skin diseases
,
bronchiolitis obliterans syndrome
,
atopic dermatitis
,
dermatitis
,
pityriasis rubra pilaris
,
leukemia
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
lymphoma
,
b-cell lymphoma
,
pregnancy
,
graft rejection
,
glycogen storage disease type ii
Digitalis
atrial fibrillation
,
cardiac arrhythmias
Hyoscyamine
breast neoplasms
,
adenocarcinoma
Anthracycline
vomiting
Endocrine
renal cell carcinoma
,
carcinoma
,
non-small-cell lung carcinoma
,
endometrial neoplasms
,
hepatocellular carcinoma
,
stomach neoplasms
,
melanoma
,
liver neoplasms
,
mesothelioma
,
gastrointestinal neoplasms
,
neuroendocrine tumors
,
type 2 diabetes mellitus
,
diabetes mellitus
,
hypertension
,
glucose metabolism disorders
,
metabolic diseases
,
endocrine system diseases
,
breast neoplasms
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