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Company ReportsPuma Biotechnology

Puma Biotechnology(PBYI)

Puma Biotechnology is a publicly traded biopharmaceutical company (NASDAQ: PBYI) headquartered in Los Angeles, CA.

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Marketed Drugs

Clinical Trials

Financial

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*Currency in USD

Company Revenue

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Annual

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*Quarterly sales USD (in millions)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Nerlynx	Neratinib	2017-07-17	2025-2031	Breast neoplasms

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

hematologic neoplasms

,

pancreatic neoplasms

,

myeloproliferative disorders

,

non-hodgkin lymphoma

,

primary myelofibrosis

,

multiple myeloma

,

precursor cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia chronic

,

,

hodgkin disease

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia chronic-phase

,

myeloid leukemia accelerated phase

,

,

,

,

,

ovarian epithelial carcinoma

,

,

hepatic insufficiency

,

gastrointestinal neoplasms

,

esophageal squamous cell carcinoma

,

,

neoplasm metastasis

,

triple negative breast neoplasms

,

brain neoplasms

,

stomach neoplasms

,

non-small-cell lung carcinoma

,

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

,

colorectal neoplasms

,

,

ovarian neoplasms

,

inflammatory breast neoplasms

,

neurofibromatosis 2

,

acoustic neuroma

,

,

,

hemangiosarcoma

,

pathologic complete response

,

hereditary sensory and autonomic neuropathies

,

,

,

,

central nervous system neoplasms

,

,

endometrial neoplasms

,

fallopian tube neoplasms

,

lobular carcinoma

,

invasive hydatidiform mole

,

pancreatic ductal carcinoma

,

ductal carcinoma

,

,

,

adenosquamous carcinoma

,

breast neoplasms

,

,

biliary tract neoplasms

,

uterine cervical neoplasms

,

urinary bladder neoplasms

,

neoadjuvant therapy

healthy volunteers/patients

pancreatic ductal carcinoma

,

pancreatic neoplasms

,

,

acinar cell carcinoma

,

myeloid leukemia acute

discoid lupus erythematosus

,

systemic lupus erythematosus

,

cutaneous lupus erythematosus

,

multiple myeloma

,

plasma cell neoplasms

,

healthy volunteers/patients

,

healthy volunteers/patients

,

colorectal neoplasms

,

chronic renal insufficiency

,

kidney diseases

,

sickle cell anemia

,

knee osteoarthritis

,

,

,

,

ovarian neoplasms

,

,

ovarian epithelial carcinoma

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

laryngeal neoplasms

,

opioid-related disorders

,

,

coronavirus infections

,

,

,

brain neoplasms

,

,

neurofibromatosis 2

,

acoustic neuroma

,

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

,

cystic fibrosis

,

,

biliary tract neoplasms

,

,

urinary bladder neoplasms

,

invasive hydatidiform mole

,

non-muscle invasive bladder neoplasms

,

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

mantle-cell lymphoma

,

b-cell lymphoma

,

b-cell leukemia

,

diabetes mellitus

,

chronic obstructive pulmonary disease

,

,

non-small-cell lung carcinoma

,

,

pulmonary eosinophilia

,

,

,

,

,

endometrial neoplasms

,

borderline personality disorder

,

personality disorders

,

churg-strauss syndrome

,

eosinophilic granuloma

,

type 2 diabetes mellitus

,

breast neoplasms

,

,

,

,

endomyocardial fibrosis

,

postoperative pain

,

,

major depressive disorder

,

depressive disorder

,

systemic lupus erythematosus

colorectal neoplasms

,

,

rectal neoplasms

,

squamous cell carcinoma of head and neck

,

chronic obstructive pulmonary disease

,

,

multiple myeloma

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

,

non-small-cell lung carcinoma

,

vision disorders

,

bcr-abl positive chronic myelogenous leukemia

,

,

neoplasm metastasis

,

,

spondylarthritis

,

,

,

,

myeloid leukemia

,

,

,

psoriatic arthritis

,

ankylosing spondylitis

,

retinal vein occlusion

,

chronic urticaria

,

,

,

cystic fibrosis

,

choroidal neovascularization

,

osteitis deformans

,

renal cell carcinoma

,

philadelphia chromosome

,

ovarian neoplasms

,

pituitary acth hypersecretion

,

,

,

myelodysplastic syndromes

,

thrombocytopenia

,

,

diabetic retinopathy

,

retinal neovascularization

,

macular degeneration

,

,

hematologic diseases

,

sickle cell anemia

,

sickle cell trait

,

vaso-occlusive crises

,

,

,

,

,

neuroendocrine tumors

,

,

,

gastrointestinal stromal tumors

,

axial spondyloarthritis

,

triple negative breast neoplasms

,

myeloid leukemia acute

,

acth-secreting pituitary adenoma

,

,

pseudomonas aeruginosa

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

respiratory aspiration

,

prostatic neoplasms

,

iga glomerulonephritis

,

myelomonocytic leukemia chronic

,

,

wet macular degeneration

,

pathologic neovascularization

,

adenocarcinoma of lung

,

brain neoplasms

,

,

hepatocellular carcinoma

,

stomach neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

carcinoid tumor

,

malignant carcinoid syndrome

,

serotonin syndrome

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

homozygous familial hypercholesterolemia

,

non-radiographic axial spondyloarthritis

,

,

lupus nephritis

,

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

allergic rhinitis seasonal

,

graft vs host disease

,

primary myelofibrosis

,

,

inclusion body myositis

,

juvenile arthritis

,

hereditary autoinflammatory diseases

,

,

familial mediterranean fever

,

diabetes mellitus

,

rheumatoid arthritis

,

hereditary sensory and autonomic neuropathies

,

,

hyperlipoproteinemia type i

,

hyperpituitarism

,

degenerative myopia

,

,

non-hodgkin lymphoma

,

,

pulmonary infarction

,

hodgkin disease

,

behcet syndrome

,

,

,

,

giant cell arteritis

,

,

thyroid neoplasms

,

food hypersensitivity

,

peanut hypersensitivity

,

polymyalgia rheumatica

,

male breast neoplasms

,

,

follicular lymphoma

,

polycythemia vera

,

,

,

myeloid leukemia chronic-phase

,

,

chronic renal insufficiency

,

kidney diseases

,

glomerulonephritis

,

urologic diseases

,

breast neoplasms

,

,

left ventricular hypertrophy

,

pathologic dilatation

,

,

essential hypertension

,

systolic murmurs

,

disease progression

Globulin, immune

macular degeneration

hereditary angioedemas

insulin resistance

,

healthy volunteers/patients

,

prediabetic state

,

,

autonomic nervous system diseases

,

orthostatic intolerance

,

,

,

status asthmaticus

,

glucose intolerance

,

digestive system physiological phenomena

,

gastrointestinal motility

,

,

,

near-infrared spectroscopy

,

,

,

,

vasoconstriction

,

allergic rhinitis

,

orthostatic hypotension

,

nervous system diseases

,

primary dysautonomias

,

,

spinal fractures

,

pharmacokinetics

,

breast neoplasms

,

,

,

non-small-cell lung carcinoma

,

,

,

brain neoplasms

,

colonic neoplasms

,

,

allergic rhinitis seasonal

,

,

alveolar soft part sarcoma

,

hemostatic disorders

,

,

granulosa cell tumor

,

amyotrophic lateral sclerosis

,

,

regional blood flow

,

ocular physiological phenomena

,

papillomavirus infections

,

vulvar diseases

,

carcinoma in situ

,

cervical intraepithelial neoplasia

,

vulvar neoplasms

,

uterine cervical dysplasia

,

parkinson disease

,

,

ventilator-associated pneumonia

,

,

,

pancreatic neoplasms

,

ductal carcinoma

,

eye axial length

,

triple negative breast neoplasms

,

degenerative myopia

,

obstructive lung diseases

,

general anesthesia

,

emergence delirium

,

,

,

,

replacement arthroplasty hip

,

,

,

,

,

,

,

anterior uveitis

,

,

,

anesthesia and analgesia

,

,

stomach neoplasms

,

neoplasm metastasis

,

retinal diseases

,

retinopathy of prematurity

,

cerebral infarction

,

replacement arthroplasty knee

,

,

blood coagulation

,

familial dysautonomia

,

vision disorders

,

,

colorectal neoplasms

,

squamous cell carcinoma

,

esophageal squamous cell carcinoma

,

,

chronic obstructive pulmonary disease

,

neuromuscular blockade

,

,

,

postoperative pain

,

,

,

delayed emergence from anesthesia

,

,

,

,

postoperative nausea and vomiting

,

drug-related side effects and adverse reactions

,

,

cesarean section

,

organophosphate poisoning

,

,

spinal anesthesia

,

respiratory distress syndrome

,

,

disease progression

,

intratracheal intubation

,

newborn respiratory distress syndrome

,

,

cognitive dysfunction

,

muscle hypotonia

,

post-dural puncture headache

,

cardiac arrhythmias

,

,

,

premature birth

,

,

,

respiratory aspiration

,

,

respiratory insufficiency

,

pulmonary atelectasis

,

,

,

retinal detachment

,

,

alzheimer disease

,

,

,

muscle relaxation

,

obstructive sleep apnea

,

sleep apnea syndromes

,

,

,

,

wounds and injuries

,

,

exercise-induced asthma

,

hip osteoarthritis

,

refractive errors

,

,

conscious sedation

,

myocardial infarction

,

,

signs and symptoms

,

cognition disorders

,

neurocognitive disorders

,

postoperative period

,

anesthesia recovery period

,

,

liver cirrhosis

,

,

newborn infant diseases

,

dental care for persons with disabilities

,

,

,

nephrolithiasis

,

,

lower urinary tract symptoms

,

esophageal achalasia

,

respiratory tract infections

,

cold temperature

,

,

bronchiolitis obliterans syndrome

,

,

hepatocellular carcinoma

,

muscle weakness

,

,

,

inferior wall myocardial infarction

,

pleural effusion

,

,

malignant pleural effusion

,

lymphadenopathy

,

pleural empyema

,

,

,

pericardial effusion

,

pleural diseases

,

pleural neoplasms

,

,

procedural pain

,

hydrophilic contact lenses

,

cystic fibrosis

,

intravenous anesthesia

,

inhalation anesthesia

,

coronary artery disease

,

,

,

conduction anesthesia

,

renal insufficiency

,

acute kidney injury

,

,

psychomotor agitation

,

,

depressive disorder

,

vascular diseases

,

,

obstetric labor complications

,

,

coronary disease

,

myocardial ischemia

,

angina pectoris

,

,

vasovagal syncope

,

,

,

diabetic retinopathy

,

,

retinal neovascularization

,

pathologic neovascularization

,

carotid stenosis

,

aortic dissection

,

thoracic surgical procedures

,

cardiac catheterization

,

blood coagulation tests

,

postoperative cognitive complications

,

,

diaphragmatic hernias congenital

,

diaphragmatic hernia

,

hypersensitivity

,

urinary bladder neoplasms

,

cardiovascular diseases

,

sudden death cardiac

,

,

,

,

,

irritable bowel syndrome

,

gastrointestinal diseases

,

,

,

,

stress echocardiography

,

diastolic heart failure

,

interstitial lung diseases

,

respiratory signs and symptoms

,

,

,

acute lung injury

,

,

,

,

,

psychology biofeedback

,

,

,

prosthesis failure

,

,

,

polymorphic catecholaminergic ventricular tachycardia

,

postural orthostatic tachycardia syndrome

,

,

,

,

gastric outlet obstruction

,

oculocardiac reflex

,

,

airway remodeling

,

airway obstruction

,

,

microvascular angina

,

variant angina pectoris

,

thoracic diseases

,

local anesthesia

,

postoperative complications

,

inguinal hernia

,

,

,

systolic murmurs

,

atrioventricular block

,

major depressive disorder

,

sick sinus syndrome

,

supraventricular tachycardia

,

,

pregnancy complications

,

myasthenia gravis

,

aortic aneurysm

,

ophthalmologic surgical procedures

,

bariatric surgery

,

,

atrial fibrillation

,

,

urinary retention

,

,

,

intraocular pressure

,

,

communicable diseases

,

unconsciousness

,

nasal surgical procedures

,

deglutition disorders

,

intraocular lymphoma

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