Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Lung neoplasms | D008175 | — | C34.90 | 1 | 1 | — | — | — | 2 |
Small cell lung carcinoma | D055752 | — | — | — | 1 | — | — | — | 1 |
Recurrence | D012008 | — | — | — | 1 | — | — | — | 1 |
Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 1 | — | — | — | 1 |
Drug common name | Alisertib |
INN | alisertib |
Description | 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxybenzoic acid is a benzazepine. |
Classification | Small molecule |
Drug class | serine/threonine kinase inhibitors |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | COc1cc(Nc2ncc3c(n2)-c2ccc(Cl)cc2C(c2c(F)cccc2OC)=NC3)ccc1C(=O)O |
PDB | — |
CAS-ID | 1028486-01-2 |
RxCUI | — |
ChEMBL ID | CHEMBL483158 |
ChEBI ID | — |
PubChem CID | 24771867 |
DrugBank | DB05220 |
UNII ID | T66ES73M18 (ChemIDplus, GSRS) |