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Company ReportsOtsuka

Otsuka

Otsuka Pharmaceutical Co., Ltd. (大塚製薬株式会社, Ōtsuka Seiyaku Kabushiki-gaisha) (TYO: 4578), abbreviated OPC, is a pharmaceutical company headquartered in Tokyo, Osaka and Naruto, Japan. The company was established August 10, 1964.

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Abilify	Aripiprazole	2002-11-15	2023-2034	Schizophrenia , Bipolar disorder , Schizophrenia spectrum and other psychotic disorders
Breathtek ubt for h-pylori	Urea c	1996-09-17		—
Busulfex	Busulfan	1999-02-04		Polycythemia vera , Primary myelofibrosis , Hematopoietic stem cell transplantation , Bcr-abl positive chronic myelogenous leukemia
Dacogen	Decitabine	2006-05-02	2028-2030	Myelodysplastic syndromes, Myeloid leukemia
Deltyba	Delamanid	2014-04-27		Multidrug-resistant tuberculosis
Inqovi	Cedazuridine, Decitabine	2020-07-07	2028-2030	Myelodysplastic syndromes, Myeloid leukemia
Jinarc	Tolvaptan	2015-05-27	2026-2030	Autosomal dominant polycystic kidney, Hyponatremia, Inappropriate adh syndrome

1

2

>

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

myelodysplastic syndromes

,

,

,

,

myeloid leukemia acute

,

myeloid leukemia

breast neoplasms

,

triple negative breast neoplasms

,

,

urologic neoplasms

,

central nervous system neoplasms

,

non-small-cell lung carcinoma

,

t-cell leukemia

,

healthy volunteers/patients

,

non-hodgkin lymphoma

,

hodgkin disease

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

neuroendocrine tumors

,

hereditary breast and ovarian cancer syndrome

,

systemic mastocytosis

,

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

squamous cell neoplasms

,

,

myeloproliferative disorders

,

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

hematopoietic stem cell transplantation

,

,

myelodysplastic-myeloproliferative diseases

,

hematologic neoplasms

,

,

residual neoplasm

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

colorectal neoplasms

,

multiple myeloma

,

plasma cell neoplasms

,

biphenotypic leukemia acute

,

myeloid leukemia chronic-phase

,

philadelphia chromosome

,

,

refractory anemia with excess of blasts

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

malignant mesothelioma

,

,

disease susceptibility

,

essential thrombocythemia

,

polycythemia vera

,

primary myelofibrosis

,

,

,

,

myelodysplastic syndromes

,

,

myeloid leukemia acute

,

,

myeloid leukemia

,

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

myelomonocytic leukemia acute

,

bcr-abl positive chronic myelogenous leukemia

,

patient preference

nephrolithiasis

,

,

cardiomyopathies

,

chronic kidney failure

,

,

,

diabetes mellitus

,

nephrogenic diabetes insipidus

,

inappropriate adh syndrome

,

,

,

,

chronic renal insufficiency

,

water-electrolyte imbalance

,

autosomal recessive polycystic kidney

,

,

water intoxication

,

,

,

hepatic encephalopathy

,

cri-du-chat syndrome

,

,

,

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

kidney diseases

,

,

liver cirrhosis

,

,

diabetes insipidus

,

healthy volunteers/patients

,

renal insufficiency

,

cardiovascular diseases

,

tricuspid valve insufficiency

,

,

,

pituitary diseases

,

nervous system trauma

,

,

urinary calculi

,

,

,

,

wasting syndrome

,

,

,

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

randomized controlled trials as topic

,

heart-assist devices

,

,

,

communicable diseases

,

extensively drug-resistant tuberculosis

,

bacterial infections

,

gram-positive bacterial infections

,

mycobacterium infections

,

latent tuberculosis

,

,

multidrug-resistant tuberculosis

,

pulmonary tuberculosis

healthy volunteers/patients

,

,

,

central nervous system diseases

,

opioid-related disorders

,

amphetamine-related disorders

,

nervous system diseases

,

cocaine-related disorders

,

,

asperger syndrome

,

trichotillomania

,

fragile x syndrome

,

excoriation disorder

,

impulsive behavior

,

developmental disabilities

,

schizophrenia spectrum and other psychotic disorders

,

behavioral symptoms

,

post-traumatic stress disorders

,

psychophysiologic disorders

,

somatoform disorders

,

,

shared paranoid disorder

,

disease progression

,

,

,

alcohol drinking

,

psychomotor agitation

,

postpartum depression

,

problem behavior

,

traumatic stress disorders

,

body weight changes

,

,

,

psychotic disorders

,

bipolar disorder

,

depressive disorder

,

,

major depressive disorder

,

mental disorders

,

autistic disorder

,

metabolic syndrome

,

tourette syndrome

,

autism spectrum disorder

,

,

,

,

alzheimer disease

,

,

treatment-resistant depressive disorder

,

,

,

hyperprolactinemia

,

attention deficit disorder with hyperactivity

,

treatment-resistant schizophrenia

,

pervasive child development disorders

,

anxiety disorders

,

,

,

,

diabetes mellitus

,

obsessive-compulsive disorder

,

compulsive personality disorder

,

insulin resistance

,

drug-related side effects and adverse reactions

,

,

substance-related disorders

,

,

anorexia nervosa

,

,

cognitive dysfunction

,

type 2 diabetes mellitus

,

physiological sexual dysfunction

,

psychotic affective disorders

,

tardive dyskinesia

,

,

,

,

gastroesophageal reflux

,

,

medication adherence

,

,

,

dysthymic disorder

,

mixed connective tissue disease

,

pharmacokinetics

,

drug-induced dyskinesia

,

feeding and eating disorders

,

,

,

,

conduct disorder

,

cardiovascular diseases

,

hyperlipidemias

,

attention deficit and disruptive behavior disorders

,

oppositional defiant disorder

,

,

parkinson disease

,

,

,

,

,

cognition disorders

,

,

metabolic diseases

,

non-alcoholic fatty liver disease

,

lipid metabolism disorders

,

mitochondrial diseases

,

drug interactions

,

wounds and injuries

,

chemical and drug induced liver injury

,

,

microvascular angina

,

therapeutic equivalency

,

conversion disorder

,

dissociative disorders

,

patient satisfaction

,

,

brain chemistry

,

,

,

,

magnetic resonance imaging

,

electroconvulsive therapy

,

periodontal diseases

,

,

,

primitive neuroectodermal tumors

,

neuroectodermal tumors

,

primitive neuroectodermal tumors peripheral

,

,

rhabdomyosarcoma

,

renal cell carcinoma

,

,

,

testicular neoplasms

,

liver neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

gastrointestinal stromal tumors

,

clear cell adenocarcinoma

,

large cell carcinoma

,

adenomyoepithelioma

,

,

,

,

,

,

,

epidermolysis bullosa dystrophica

,

systemic scleroderma

,

systemic lupus erythematosus

,

diffuse scleroderma

,

osteogenesis imperfecta

,

prolymphocytic leukemia t-cell

,

metabolic brain diseases

,

primary effusion lymphoma

,

,

alpha-thalassemia

,

non-hodgkin lymphoma

,

hodgkin disease

,

b-cell chronic lymphocytic leukemia

,

primary myelofibrosis

,

chronic granulomatous disease

,

biphenotypic leukemia acute

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

burkitt lymphoma

,

follicular lymphoma

,

central nervous system neoplasms

,

b-cell lymphoma marginal zone

,

t-cell lymphoma peripheral

,

,

extranodal nk-t-cell lymphoma

,

primary immunodeficiency diseases

,

t-cell lymphoma cutaneous

,

large-cell lymphoma immunoblastic

,

myeloid leukemia accelerated phase

,

large-cell lymphoma anaplastic

,

paroxysmal hemoglobinuria

,

germ cell and embryonal neoplasms

,

plasmablastic lymphoma

,

lymphomatoid granulomatosis

,

thrombocytopenia

,

nervous system neoplasms

,

,

polycythemia vera

,

,

metabolic diseases

,

prolymphocytic leukemia

,

,

common variable immunodeficiency

,

sezary syndrome

,

mycosis fungoides

,

,

mannosidase deficiency diseases

,

residual neoplasm

,

wiskott-aldrich syndrome

,

bone marrow transplantation

,

kidney neoplasms

,

mucopolysaccharidosis vi

,

alpha-mannosidosis

,

brain neoplasms

,

intraocular lymphoma

,

,

,

precancerous conditions

,

adult t-cell leukemia-lymphoma

,

epidermolysis bullosa

,

chronic disease

,

,

mucopolysaccharidosis vii

,

aspartylglucosaminuria

,

sphingolipidoses

,

plasma cell leukemia

,

medulloblastoma

,

metabolic syndrome

,

acquired immunodeficiency syndrome

,

autoimmune lymphoproliferative syndrome

,

immunoblastic lymphadenopathy

,

large granular lymphocytic leukemia

,

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

,

metabolic brain diseases inborn

,

mucopolysaccharidosis ii

,

peroxisomal disorders

,

immunoglobulin light-chain amyloidosis

,

,

,

hairy cell leukemia

,

oligodendroglioma

,

hemoglobin sc disease

,

multiple sclerosis

,

urologic neoplasms

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

,

leukoencephalopathies

,

zellweger syndrome

,

infantile refsum disease

,

,

mitochondrial encephalomyopathies

,

male breast neoplasms

,

inflammatory breast neoplasms

,

,

macrophage activation syndrome

,

gata2 deficiency

,

mast-cell leukemia

,

,

thymus neoplasms

,

reactive arthritis

,

,

leukemia myeloid chronic atypical bcr-abl negative

,

,

neutrophilic leukemia chronic

,

,

,

dyskeratosis congenita

,

homologous transplantation

,

frontotemporal dementia

,

type b niemann-pick disease

,

primary progressive aphasia

,

paraproteinemias

,

deficiency diseases

,

hemolytic anemia

,

lysosomal storage diseases

,

genetic therapy

,

triple negative breast neoplasms

,

,

cell transplantation

,

respiratory signs and symptoms

,

,

aids-related lymphoma

,

hypochromic anemia

,

sideroblastic anemia

,

cord blood stem cell transplantation

,

congenital abnormalities

,

neurofibromatosis 1

,

neurofibromatoses

,

chromosome aberrations

,

chromosome disorders

,

spontaneous remission

,

disease-free survival

,

,

,

,

hematologic neoplasms

,

plasma cell neoplasms

,

bcr-abl positive chronic myelogenous leukemia

,

,

myelodysplastic-myeloproliferative diseases

,

immunologic deficiency syndromes

,

sickle cell anemia

,

hematologic diseases

,

,

myelomonocytic leukemia chronic

,

severe combined immunodeficiency

,

hemoglobinopathies

,

,

t-cell lymphoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

lymphoproliferative disorders

,

bone marrow failure disorders

,

,

classical conditioning

,

,

,

neoplasm metastasis

,

diamond-blackfan anemia

,

,

x-linked combined immunodeficiency diseases

,

myelomonocytic leukemia acute

,

refractory anemia with excess of blasts

,

,

fanconi syndrome

,

megakaryoblastic leukemia acute

,

erythroblastic leukemia acute

,

stem cell transplantation

,

,

hemophagocytic lymphohistiocytosis

,

inborn genetic diseases

,

mucopolysaccharidosis i

,

,

immune system diseases

,

t-cell leukemia

,

monocytic leukemia acute

,

mucopolysaccharidoses

,

adrenoleukodystrophy

,

langerhans-cell histiocytosis

,

breast neoplasms

,

peripheral blood stem cell transplantation

,

refractory anemia

,

shwachman-diamond syndrome

,

essential thrombocythemia

,

,

,

globoid cell leukodystrophy

,

metachromatic leukodystrophy

,

myeloid sarcoma

,

promyelocytic leukemia acute

,

chediak-higashi syndrome

,

inborn errors metabolism

,

niemann-pick diseases

,

type a niemann-pick disease

,

type c niemann-pick disease

,

ganglioneuroblastoma

,

pathologic complete response

,

ovarian neoplasms

,

hypereosinophilic syndrome

,

eosinophilic leukemia acute

,

,

pick disease of the brain

,

philadelphia chromosome

,

whole-body irradiation

,

,

ovarian epithelial carcinoma

,

neuronal ceroid-lipofuscinoses

,

tay-sachs disease

,

sandhoff disease

,

gm1 gangliosidosis

,

gaucher disease

,

,

basophilic leukemia acute

,

,

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

myeloid leukemia

,

,

,

multiple myeloma

,

precursor cell lymphoblastic leukemia-lymphoma

,

myeloproliferative disorders

,

lymphoid leukemia

,

graft vs host disease

,

hematopoietic stem cell transplantation

,

,

,

myelomonocytic leukemia juvenile

,

,

beta-thalassemia

,

aplastic anemia

,

myeloid leukemia chronic-phase

,

bronchiolitis obliterans syndrome

,

,

genetic polymorphism

,

type 1 hyper-igm immunodeficiency syndrome

,

hyper-igm immunodeficiency syndrome

,

,

,

retinal neoplasms

,

phenylketonurias

,

agammaglobulinemia

,

leukocyte-adhesion deficiency syndrome

,

hereditary congenital and neonatal diseases and abnormalities

,

,

bone marrow diseases

,

,

pure red-cell aplasia

Aripiprazole lauroxil

healthy volunteers/patients

,

,

,

central nervous system diseases

,

opioid-related disorders

,

amphetamine-related disorders

,

nervous system diseases

,

cocaine-related disorders

,

,

asperger syndrome

,

trichotillomania

,

fragile x syndrome

,

excoriation disorder

,

impulsive behavior

,

developmental disabilities

,

schizophrenia spectrum and other psychotic disorders

,

behavioral symptoms

,

post-traumatic stress disorders

,

psychophysiologic disorders

,

somatoform disorders

,

,

shared paranoid disorder

,

disease progression

,

,

,

alcohol drinking

,

psychomotor agitation

,

postpartum depression

,

problem behavior

,

traumatic stress disorders

,

body weight changes

,

,

,

psychotic disorders

,

bipolar disorder

,

depressive disorder

,

,

major depressive disorder

,

mental disorders

,

autistic disorder

,

metabolic syndrome

,

tourette syndrome

,

autism spectrum disorder

,

,

,

,

alzheimer disease

,

,

treatment-resistant depressive disorder

,

,

,

hyperprolactinemia

,

attention deficit disorder with hyperactivity

,

treatment-resistant schizophrenia

,

pervasive child development disorders

,

anxiety disorders

,

,

,

,

diabetes mellitus

,

obsessive-compulsive disorder

,

compulsive personality disorder

,

insulin resistance

,

drug-related side effects and adverse reactions

,

,

substance-related disorders

,

,

anorexia nervosa

,

,

cognitive dysfunction

,

type 2 diabetes mellitus

,

physiological sexual dysfunction

,

psychotic affective disorders

,

tardive dyskinesia

,

,

,

,

gastroesophageal reflux

,

,

medication adherence

,

,

,

dysthymic disorder

,

mixed connective tissue disease

,

pharmacokinetics

,

drug-induced dyskinesia

,

feeding and eating disorders

,

,

,

,

conduct disorder

,

cardiovascular diseases

,

hyperlipidemias

,

attention deficit and disruptive behavior disorders

,

oppositional defiant disorder

,

,

parkinson disease

,

,

,

,

,

cognition disorders

,

,

metabolic diseases

,

non-alcoholic fatty liver disease

,

lipid metabolism disorders

,

mitochondrial diseases

,

drug interactions

,

wounds and injuries

,

chemical and drug induced liver injury

,

,

microvascular angina

,

therapeutic equivalency

,

conversion disorder

,

dissociative disorders

,

patient satisfaction

,

,

brain chemistry

,

,

,

,

magnetic resonance imaging

,

electroconvulsive therapy

,

periodontal diseases

,

,

healthy volunteers/patients

atopic dermatitis

,

,

,

healthy volunteers/patients

,

,

chronic hepatitis c

,

,

,

,

major depressive disorder

,

depressive disorder

large b-cell lymphoma diffuse

,

multiple myeloma

,

b-cell chronic lymphocytic leukemia

,

follicular lymphoma

,

,

,

,

hodgkin disease

,

mantle-cell lymphoma

,

b-cell lymphoma

,

triple negative breast neoplasms

,

renal cell carcinoma

,

,

,

,

chronic hepatitis b

,

communicable diseases

,

,

parkinson disease

,

parkinsonian disorders

,

movement disorders

,

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

chronic renal insufficiency

,

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

graft vs host disease

,

type 1 diabetes mellitus

,

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

brain neoplasms

,

,

oligodendroglioma

,

pancreatic neoplasms

,

,

neuroendocrine tumors

,

islet cell carcinoma

,

,

,

somatostatinoma

,

,

,

breast neoplasms

,

myelodysplastic syndromes

,

thrombocytopenia

,

,

,

,

retinal vein occlusion

,

vision disorders

,

,

macular degeneration

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

juvenile arthritis

,

,

kidney diseases

,

myocardial infarction

,

,

inferior wall myocardial infarction

,

organ transplantation

,

wet macular degeneration

,

neoplasm metastasis

,

graft rejection

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

,

non-alcoholic fatty liver disease

,

,

postoperative pain

,

,

choroidal neovascularization

,

pathologic neovascularization

,

chronic kidney failure

,

renal insufficiency

,

liver transplantation

,

kidney transplantation

,

,

,

,

ankylosing spondylitis

,

spondylarthritis

,

,

liver cirrhosis

,

,

atrial fibrillation

Calcium carbonate

,

chronic renal insufficiency

,

kidney diseases

,

hyperparathyroidism

,

secondary hyperparathyroidism

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