Delamanid
Deltyba (delamanid) is a small molecule pharmaceutical. Delamanid was first approved as Deltyba on 2014-04-27. It has been approved in Europe to treat multidrug-resistant tuberculosis.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
Trade Name
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Drug Products
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Clinical
Clinical Trials
44 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | 3 | 17 | 9 | 2 | 6 | 34 |
| Multidrug-resistant tuberculosis | D018088 | EFO_0007381 | — | 2 | 10 | 7 | 3 | 4 | 25 |
| Pulmonary tuberculosis | D014397 | EFO_1000049 | A15 | 1 | 17 | 5 | 1 | — | 22 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | 1 | 1 | — | — | 2 |
| Extensively drug-resistant tuberculosis | D054908 | — | — | — | 1 | 1 | — | — | 2 |
| Bacterial infections | D001424 | — | A49 | — | — | 2 | — | — | 2 |
| Communicable diseases | D003141 | — | — | — | — | 1 | — | — | 1 |
| Gram-positive bacterial infections | D016908 | — | — | — | — | 1 | — | — | 1 |
| Mycobacterium infections | D009164 | — | A31.9 | — | — | 1 | — | — | 1 |
| Latent tuberculosis | D055985 | — | Z22.7 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hiv infections | D015658 | EFO_0000764 | B20 | 1 | 2 | — | — | 2 | 4 |
| Hiv | D006678 | — | O98.7 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Delamanid |
| INN | delamanid |
| Description | Delamanid is a member of piperidines. |
| Classification | Small molecule |
| Drug class | mycolic acid inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[C@]1(COc2ccc(N3CCC(Oc4ccc(OC(F)(F)F)cc4)CC3)cc2)Cn2cc([N+](=O)[O-])nc2O1 |
Identifiers
| PDB | — |
| CAS-ID | 681492-22-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL218650 |
| ChEBI ID | — |
| PubChem CID | 6480466 |
| DrugBank | DB11637 |
| UNII ID | 8OOT6M1PC7 (ChemIDplus, GSRS) |
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Safety
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1,681 adverse events reported
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