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AboutPricing
Drug ReportsRebamipide
Rebamipide
Rebamipide is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target cholecystokinin receptor type A.
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
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Completion date
Results first post date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A02: Drugs for acid related disorders
— A02B: Drugs for peptic ulcer and gastro-oesophageal reflux disease (gord)
— A02BX: Other drugs for peptic ulcer and gastro-oesophageal reflux disease (gord) in atc
— A02BX14: Rebamipide
HCPCS
No data
Clinical
Clinical Trials
53 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Keratoconjunctivitis siccaD007638EFO_1000906———2——2
Dry eye syndromesD015352—H04.12——2——2
KeratoconjunctivitisD007637—H16.2——2——2
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameRebamipide
INNrebamipide
Description
2-[[(4-chlorophenyl)-oxomethyl]amino]-3-(2-oxo-1H-quinolin-4-yl)propanoic acid is a secondary carboxamide.
Classification
Small molecule
Drug class—
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Structure (InChI/SMILES or Protein Sequence)
O=C(NC(Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1
Identifiers
PDB—
CAS-ID90098-04-7
RxCUI—
ChEMBL IDCHEMBL1697771
ChEBI ID—
PubChem CID5042
DrugBankDB11656
UNII IDLR583V32ZR (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CCKAR
CCKAR
Organism
Homo sapiens
Gene name
CCKAR
Gene synonyms
CCKRA
NCBI Gene ID
886
Protein name
cholecystokinin receptor type A
Protein synonyms
CCK-A receptor, CCK-AR, CCK1-R, cholecystokinin type 1 receptor, cholecystokinin type-A receptor, Cholecystokinin-1 receptor
Uniprot ID
P32238
Mouse ortholog
Cckar (12425)
cholecystokinin receptor type A (Q9DBV6)
Variants
No data
Financial
Revenue by drug
$
€
£
₣
Rebamipide – Kubota Pharmaceutical
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Estimated US medical usage
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,729 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1,051 adverse events reported
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