Ulotaront
Ulotaront is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
31 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Schizophrenia | D012559 | EFO_0000692 | F20 | 12 | 3 | 10 | — | — | 24 |
| Anxiety disorders | D001008 | EFO_0006788 | F41.1 | — | 1 | 4 | — | — | 4 |
| Generalized anxiety disorder | D000098647 | — | — | — | 1 | 4 | — | — | 4 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Mental disorders | D001523 | EFO_0000677 | F91.9 | — | 2 | — | — | — | 2 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | 1 | — | — | — | 1 |
| Psychotic disorders | D011618 | — | F20.81 | — | 1 | — | — | — | 1 |
| Depression | D003863 | — | F33.9 | — | 1 | — | — | — | 1 |
| Major depressive disorder | D003865 | EFO_0003761 | F22 | — | 1 | — | — | — | 1 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Narcolepsy | D009290 | EFO_0000614 | G47.4 | 1 | — | — | — | — | 1 |
| Cataplexy | D002385 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Ulotaront |
| INN | ulotaront |
| Description | Ulotaront is a member of the class of thienopyrans that is 4,7-dihydro-5H-thieno[2,3-c]pyran substituted by a (methylamino)methyl at position 7S. It is a trace amine-associated receptor 1 and serotonin 5-HT1A receptors agonist that has demonstrated efficacy in the treatment of patients with schizophrenia. It has a role as a trace amine-associated receptor 1 agonist, a psychotropic drug, an antidepressant, an antipsychotic agent and a serotonergic agonist. It is a secondary amino compound and a thienopyran. |
| Classification | Small molecule |
| Drug class | trace amine associated receptor (TAAR) agonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CNC[C@@H]1OCCc2ccsc21 |
Identifiers
| PDB | — |
| CAS-ID | 1310426-33-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4650337 |
| ChEBI ID | — |
| PubChem CID | 89532783 |
| DrugBank | DB15665 |
| UNII ID | 3K6270MG59 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
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Adverse Events
0 adverse events reported
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