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Company ReportsAxsome Therapeutics

Axsome Therapeutics(AXSM)

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Auvelity	Dextromethorphan, Bupropion	2022-08-18	2023-2040	Atrial fibrillation , Atrial flutter , Cardiac arrhythmias , Cough , Neurobehavioral manifestations , Sinusitis , Asthma , Common cold , Allergic rhinitis perennial , Urticaria , Vasomotor rhinitis , Whooping cough , Bronchitis , Pharyngitis , Laryngitis , Postoperative complications , Pain , Vomiting , Nausea , Anaphylaxis , Allergic conjunctivitis , Motion sickness , Tobacco use disorder , Attention deficit disorder with hyperactivity , Depressive disorder

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

migraine without aura

,

migraine with aura

,

,

,

migraine disorders

,

,

,

,

brain neoplasms

,

parkinson disease

,

multiple sclerosis

,

restless legs syndrome

,

post-concussion syndrome

,

cognitive dysfunction

,

post-traumatic headache

,

motion sickness

,

cardiovascular diseases

,

Dextromethorphan

drug interactions

,

,

,

,

,

,

hairy cell leukemia

,

,

traumatic stress disorders

,

vascular diseases

,

,

brain hypoxia-ischemia

,

castration-resistant prostatic neoplasms

,

endometrioid carcinoma

,

ovarian epithelial carcinoma

,

food-drug interactions

,

malignant mesothelioma

,

oligodendroglioma

,

pituitary diseases

,

alcohol drinking

,

post-dural puncture headache

,

beta-thalassemia

,

,

hemoglobinopathies

,

aortic coarctation

,

mitochondrial diseases

,

acute intermittent porphyria

,

hereditary coproporphyria

,

erythropoietic porphyria

,

,

hepatic porphyrias

,

therapeutic equivalency

,

hereditary angioedemas

,

,

cytomegalovirus

,

systemic mastocytosis

,

,

renal cell carcinoma

,

voice disorders

,

,

,

autonomic nervous system diseases

,

stomach neoplasms

,

lacrimal apparatus diseases

,

procedural pain

,

separation anxiety

,

,

,

neuroepithelial neoplasms

,

medulloblastoma

,

,

,

,

spinal cord neoplasms

,

large granular lymphocytic leukemia

,

pituitary neoplasms

,

choroid plexus neoplasms

,

craniopharyngioma

,

primitive neuroectodermal tumors

,

choriocarcinoma

,

,

,

,

endodermal sinus tumor

,

neuroectodermal tumors

,

,

phenylketonurias

,

chromophobe adenoma

,

basophil adenoma

,

acidophil adenoma

,

,

solitary pulmonary nodule

,

lymphoproliferative disorders

,

blood coagulation disorders

,

hemostatic disorders

,

paraproteinemias

,

immunoproliferative disorders

,

hemorrhagic disorders

,

,

critical illness

,

,

high-intensity focused ultrasound ablation

,

,

retinal telangiectasis

,

retinal perforations

,

african trypanosomiasis

,

trypanosomiasis

,

,

,

,

waldenstrom macroglobulinemia

,

hematologic neoplasms

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

burkitt lymphoma

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

,

,

b-cell chronic lymphocytic leukemia

,

t-cell lymphoma cutaneous

,

bcr-abl positive chronic myelogenous leukemia

,

cholangiocarcinoma

,

ovarian neoplasms

,

renal insufficiency

,

plasma cell leukemia

,

liver neoplasms

,

large-cell lymphoma anaplastic

,

adult t-cell leukemia-lymphoma

,

,

conscious sedation

,

squamous cell carcinoma of head and neck

,

germ cell and embryonal neoplasms

,

sezary syndrome

,

myeloid leukemia chronic-phase

,

mycosis fungoides

,

large-cell lymphoma immunoblastic

,

,

,

blastic plasmacytoid dendritic cell neoplasm

,

wounds and injuries

,

squamous cell neoplasms

,

esophageal neoplasms

,

intraocular lymphoma

,

lymphomatoid granulomatosis

,

residual neoplasm

,

,

squamous cell carcinoma

,

myeloid leukemia accelerated phase

,

testicular neoplasms

,

,

uveal neoplasms

,

,

pancreatic neoplasms

,

smoking cessation

,

,

myofascial pain syndromes

,

,

neurodegenerative diseases

,

spinal cord injuries

,

trigeminal neuralgia

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

,

,

vitreous hemorrhage

,

pathologic complete response

,

immunoblastic lymphadenopathy

,

,

nervous system neoplasms

,

airway obstruction

,

small cell lung carcinoma

,

,

,

sleep wake disorders

,

,

pheochromocytoma

,

b-cell leukemia

,

radiation injuries

,

wet macular degeneration

,

,

endocrine gland neoplasms

,

pelvic organ prolapse

,

clonal hematopoiesis

,

,

bone marrow transplantation

,

homologous transplantation

,

autologous transplantation

,

pulmonary tuberculosis

,

gram-positive bacterial infections

,

tobacco use disorder

,

cigarette smoking

,

peripheral nervous system diseases

,

,

,

irritable bowel syndrome

,

facial neuralgia

,

,

,

biliary tract neoplasms

,

,

,

epstein-barr virus infections

,

oral lichen planus

,

,

fuchs' endothelial dystrophy

,

hereditary corneal dystrophies

,

retinitis pigmentosa

,

,

treatment refusal

,

,

,

retinal neovascularization

,

plasmablastic lymphoma

,

,

,

,

small cell carcinoma

,

,

atrial heart septal defects

,

heart septal defects

,

ventricular heart septal defects

,

endocardial cushion defects

,

anxiety disorders

,

obsessive-compulsive disorder

,

somatoform disorders

,

body dysmorphic disorders

,

retinal degeneration

,

,

multiple chronic conditions

,

,

mucinous adenocarcinoma

,

carbon monoxide poisoning

,

postherpetic neuralgia

,

,

,

non-hodgkin lymphoma

,

immunoglobulin light-chain amyloidosis

,

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

large b-cell lymphoma diffuse

,

neoplasm metastasis

,

b-cell lymphoma

,

hodgkin disease

,

myeloid leukemia acute

,

,

brain neoplasms

,

myeloid leukemia

,

philadelphia chromosome

,

smoldering multiple myeloma

,

myelodysplastic syndromes

,

,

t-cell leukemia

,

hypersensitivity

,

,

,

central nervous system neoplasms

,

treatment-resistant depressive disorder

,

respiratory distress syndrome

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia acute

,

,

cesarean section

,

colonic neoplasms

,

rectal neoplasms

,

amyotrophic lateral sclerosis

,

,

multiple sclerosis

,

,

acute lung injury

,

newborn respiratory distress syndrome

,

ataxia telangiectasia

,

,

,

,

,

myeloproliferative disorders

,

,

myelomonocytic leukemia juvenile

,

hematologic diseases

,

disease progression

,

rotator cuff injuries

,

,

motor neuron disease

,

,

,

,

substance-related disorders

,

adrenocortical hyperfunction

,

inborn genetic diseases

,

,

congenital adrenal hyperplasia

,

acute kidney injury

,

male breast neoplasms

,

,

huntington disease

,

bipolar disorder

,

autistic disorder

,

acquired immunodeficiency syndrome

,

,

diabetic neuropathies

,

human influenza

,

viral pneumonia

,

,

cochlear implants

,

,

adrenogenital syndrome

,

,

infectious skin diseases

,

,

bone marrow diseases

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

erythroblastic leukemia acute

,

inguinal hernia

,

,

tetralogy of fallot

,

personal satisfaction

,

spinal diseases

,

noninvasive ventilation

,

cardiopulmonary bypass

,

promyelocytic leukemia acute

,

inflammatory breast neoplasms

,

abdominal neoplasms

,

,

amphetamine-related disorders

,

addictive behavior

,

autism spectrum disorder

,

pervasive child development disorders

,

relapsing-remitting multiple sclerosis

,

,

precancerous conditions

,

intestinal neoplasms

,

coronavirus infections

,

cerebellar ataxia

,

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

ureteral neoplasms

,

,

,

hyperbilirubinemia

,

,

conduction anesthesia

,

replacement arthroplasty hip

,

,

,

,

subdural hematoma

,

,

,

ocular motility disorders

,

,

opsoclonus-myoclonus syndrome

,

,

immune reconstitution inflammatory syndrome

,

,

allergic rhinitis

,

allergic rhinitis perennial

,

,

,

,

,

basophilic leukemia acute

,

eosinophilic leukemia acute

,

refractory anemia with excess of blasts

,

refractory anemia

,

rapid sequence induction and intubation

,

intratracheal intubation

,

vaginal hysterectomy

,

suburethral slings

,

,

,

neurodevelopmental disorders

,

pulmonary hypertension

,

breast carcinoma in situ

,

nasal obstruction

,

,

,

carcinoma in situ

,

spinal dysraphism

,

,

acanthamoeba keratitis

,

,

hematopoietic stem cell mobilization

,

dermatologic surgical procedures

,

multiple myeloma

,

plasma cell neoplasms

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

lymphoid leukemia

,

,

postoperative pain

,

,

,

,

healthy volunteers/patients

,

,

,

retinal vein occlusion

,

,

,

,

breast neoplasms

,

thrombocytopenic purpura idiopathic

,

postoperative nausea and vomiting

,

,

,

thrombocytopenia

,

mantle-cell lymphoma

,

major depressive disorder

,

dry eye syndromes

,

,

depressive disorder

,

emergence delirium

,

prostatic neoplasms

,

,

alzheimer disease

,

psychomotor agitation

,

,

diabetic retinopathy

,

diabetes mellitus

,

t-cell lymphoma

,

,

,

non-small-cell lung carcinoma

,

,

replacement arthroplasty knee

,

cognitive dysfunction

,

t-cell lymphoma peripheral

,

colorectal neoplasms

,

,

,

pain management

,

,

parkinson disease

,

obstructive sleep apnea

,

epiretinal membrane

,

drug-related side effects and adverse reactions

,

,

biphenotypic leukemia acute

,

retinal diseases

,

sensorineural hearing loss

,

,

anesthesia and analgesia

,

,

,

,

,

,

,

opioid-related disorders

,

macular degeneration

,

vision disorders

,

spinal anesthesia

,

migraine disorders

,

,

extranodal nk-t-cell lymphoma

,

,

traumatic brain injuries

,

cataract extraction

,

,

posterior uveitis

,

,

postoperative complications

,

,

postoperative cognitive complications

,

,

post-traumatic stress disorders

,

congenital abnormalities

,

,

capsule opacification

,

knee osteoarthritis

,

,

,

,

intravenous substance abuse

,

pseudobulbar palsy

,

attention deficit disorder with hyperactivity

,

,

cognition disorders

,

sleep apnea syndromes

,

respiratory insufficiency

,

retinal detachment

,

,

,

,

,

,

thrombocytopenic purpura

,

,

allergic conjunctivitis

,

congenital heart defects

,

cardiac surgical procedures

,

,

ulcerative colitis

,

,

,

respiratory sounds

,

local anesthesia

,

brachial plexus block

,

,

hip osteoarthritis

,

shoulder injuries

,

type 2 diabetes mellitus

,

respiratory tract infections

,

,

,

hemophagocytic lymphohistiocytosis

,

patient preference

,

intervertebral disc displacement

,

pathologic constriction

,

spinal stenosis

,

,

,

anterior uveitis

,

,

,

trigger finger disorder

,

,

subdural hematoma chronic

,

,

nervous system diseases

,

,

,

femoral neck fractures

,

chronic obstructive pulmonary disease

,

mental disorders

,

,

cardiac arrhythmias

,

,

carpal tunnel syndrome

,

gastrointestinal neoplasms

,

sickle cell anemia

,

,

,

,

shoulder impingement syndrome

,

,

,

,

,

neurocognitive disorders

,

,

,

penetrating keratoplasty

,

intraocular pressure

,

,

vitreoretinal surgery

,

,

refractive surgical procedures

,

peripheral arterial disease

,

peripheral vascular diseases

,

,

,

premature birth

,

,

endophthalmitis

,

head and neck neoplasms

,

,

intermediate uveitis

,

,

descemet stripping endothelial keratoplasty

,

,

,

,

magnetic resonance imaging

,

cytokine release syndrome

,

reperfusion injury

,

,

radius fractures

,

wrist fractures

,

,

,

graft rejection

,

urethral stricture

,

gastrointestinal diseases

,

inflammatory bowel diseases

,

digestive system diseases

,

intestinal diseases

,

ambulatory surgical procedures

,

pain measurement

,

ankle fractures

,

,

graft vs host disease

,

,

pharmacokinetics

,

meibomian gland dysfunction

,

,

atherosclerosis

,

treatment outcome

,

,

corneal transplantation

,

viral bronchiolitis

,

temporomandibular joint disorders

,

orthopedic procedures

,

corneal endothelial cell loss

,

,

kidney diseases

,

,

status asthmaticus

,

meningeal tuberculosis

,

,

bites and stings

,

dental deposits

,

femoral fractures

,

,

sjogren's syndrome

,

patient-controlled analgesia

,

premature obstetric labor

,

arteriovenous malformations

,

sudden hearing loss

,

,

,

,

neurologic manifestations

,

signs and symptoms

,

neurobehavioral manifestations

,

substance withdrawal syndrome

,

alcohol withdrawal delirium

,

,

obstetrical analgesia

,

,

oxidative stress

,

neuromuscular blockade

,

persistent vegetative state

,

thoracic injuries

,

arteriovenous fistula

,

urologic surgical procedures

,

,

,

gastroesophageal reflux

,

peptic esophagitis

,

,

,

anterior cruciate ligament injuries

,

,

,

,

foot deformities

,

,

congenital foot deformities

,

kidney transplantation

,

treatment-resistant schizophrenia

,

,

,

percutaneous nephrolithotomy

,

dupuytren contracture

,

,

fracture fixation

,

elbow tendinopathy

,

,

water intoxication

,

,

deep brain stimulation

,

,

bilateral hearing loss

,

,

neurotoxicity syndromes

,

pituitary acth hypersecretion

,

,

deglutition disorders

,

,

thyroid diseases

,

,

intravenous anesthesia

,

,

breast cancer lymphedema

,

intranasal administration

,

,

neuroinflammatory diseases

,

digestive system neoplasms

,

,

mucinous cystadenocarcinoma

,

serous cystadenocarcinoma

,

fallopian tube neoplasms

,

cystadenocarcinoma

,

myelodysplastic-myeloproliferative diseases

,

trophoblastic neoplasms

,

primary myelofibrosis

,

leukemia myeloid chronic atypical bcr-abl negative

,

neutrophilic leukemia chronic

,

,

ureterolithiasis

,

prostatic hyperplasia

,

bariatric surgery

,

vascular dementia

,

lewy body disease

,

hyperhomocysteinemia

,

vitamin b 12 deficiency

,

,

frontotemporal dementia

,

tdp-43 proteinopathies

,

iron deficiencies

,

rheumatoid arthritis

,

hypertrophic cicatrix

,

,

,

pituitary dwarfism

,

,

morphine dependence

,

,

,

patient reported outcome measures

,

patient satisfaction

,

acth-secreting pituitary adenoma

,

ocular hypertension

,

optic nerve diseases

,

,

hyaline membrane disease

,

chronic urticaria

,

,

dentin sensitivity

,

,

,

,

,

,

thoracic surgical procedures

,

,

soft tissue infections

,

,

,

,

,

transient tachypnea of the newborn

,

thyroid neoplasms

,

vocal cord paralysis

,

adrenocortical adenoma

,

cushing syndrome

,

postoperative hemorrhage

,

parathyroid diseases

,

,

,

meningeal carcinomatosis

,

cholecystectomy

,

elective surgical procedures

,

general anesthesia

,

nutritional and metabolic diseases

,

,

coronary disease

,

off-pump coronary artery bypass

,

cerebral infarction

,

cerebrovascular disorders

,

intracranial hypertension

,

,

,

,

metabolic syndrome

,

atrial fibrillation

,

intervertebral disc degeneration

,

respiratory aspiration

,

sleep initiation and maintenance disorders

,

,

out-of-hospital cardiac arrest

,

psychological distress

,

,

st elevation myocardial infarction

,

percutaneous coronary intervention

,

,

artificial respiration

,

pruritus vulvae

,

coronary artery disease

,

,

intravenous administration

,

dental pulp necrosis

,

,

animal mammary neoplasms

,

,

obstetrical anesthesia

,

median neuropathy

,

,

psychotic disorders

,

subarachnoid hemorrhage

,

endovascular procedures

,

supratentorial neoplasms

,

sphenopalatine ganglion block

,

,

hyperaldosteronism

,

,

urinary retention

healthy volunteers/patients

,

,

depressive disorder

,

tobacco use disorder

,

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

cardiovascular diseases

,

systemic lupus erythematosus

,

feeding behavior

,

pharmacokinetics

,

,

non-hodgkin lymphoma

,

multiple myeloma

,

,

inguinal hernia

,

,

,

hodgkin disease

,

,

,

,

,

,

migraine disorders

,

,

,

juvenile arthritis

,

brain neoplasms

,

second primary neoplasms

,

neoplasm metastasis

,

,

,

,

,

,

,

postpartum period

,

,

prostatic neoplasms

,

replacement arthroplasty hip

,

,

urinary incontinence

,

stress urinary incontinence

,

,

,

postoperative pain

,

healthy volunteers/patients

,

,

knee osteoarthritis

,

rheumatoid arthritis

,

,

,

ankylosing spondylitis

,

pain management

,

opioid-related disorders

,

,

rotator cuff injuries

,

axial spondyloarthritis

,

,

,

replacement arthroplasty knee

,

,

,

,

nephrolithiasis

,

,

,

spondylarthritis

,

biliary atresia

,

,

bariatric surgery

,

sensation disorders

,

,

,

hip osteoarthritis

,

drug-related side effects and adverse reactions

,

drug interactions

,

,

,

,

,

,

,

,

ankle fractures

,

hammer toe syndrome

,

tailor's bunion

,

,

anxiety disorders

,

,

catastrophization

,

rheumatic diseases

,

collagen diseases

,

Bupropion hydrochloride

healthy volunteers/patients

,

,

depressive disorder

,

tobacco use disorder

,

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

cardiovascular diseases

,

,

non-small-cell lung carcinoma

,

,

small cell lung carcinoma

,

adenocarcinoma of lung

,

bronchiolo-alveolar adenocarcinoma

multiple myeloma

,

plasma cell neoplasms

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

colorectal neoplasms

,

,

non-small-cell lung carcinoma

,

,

neoplasm metastasis

,

breast neoplasms

,

,

head and neck neoplasms

,

,

small cell lung carcinoma

,

adenocarcinoma of lung

,

bronchiolo-alveolar adenocarcinoma

,

prostatic neoplasms

,

ovarian neoplasms

,

pancreatic neoplasms

,

,

ovarian epithelial carcinoma

,

,

cardiovascular diseases

,

coronary disease

,

diabetes mellitus

,

coronary artery disease

,

myocardial ischemia

,

,

peripheral arterial disease

,

peripheral vascular diseases

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