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Insmed(INSM)

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Therapeutic Areas:

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Arikayce	Amikacin	2018-09-28	2024-2035	Respiratory tract infections , Urinary tract infections , Bacterial infections , Intraabdominal infections , Pseudomonas infections , Infectious skin diseases , Escherichia coli infections , Soft tissue infections , Surgical wound infection , Staphylococcal infections , Burns , Endocarditis , Central nervous system infections , Proteus infections , Infectious bone diseases , Acinetobacter infections , Klebsiella infections , Mycobacterium infections , Serratia infections
Iplex	Mecasermin rinfabate	2005-12-12		—

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

urinary tract infections

,

intraabdominal infections

Mecasermin rinfabate

myotonic dystrophy

,

,

psoriatic arthritis

,

,

,

intestinal volvulus

,

large b-cell lymphoma diffuse

,

b-cell chronic lymphocytic leukemia

,

,

lymphoid leukemia

,

non-hodgkin lymphoma

,

,

follicular lymphoma

,

healthy volunteers/patients

,

renal insufficiency

,

,

hepatic insufficiency

,

cystic fibrosis

,

,

,

,

,

hidradenitis suppurativa

,

,

,

,

brain neoplasms

,

nutritional status

,

,

pneumococcal pneumonia

,

,

male breast neoplasms

,

respiratory tract infections

,

embryo transfer

,

,

,

,

postpartum hemorrhage

,

inflammatory bowel diseases

,

,

tendon injuries

,

,

community-acquired infections

,

haemophilus influenzae

,

streptococcus pneumoniae

,

prostatic neoplasms

,

cytomegalovirus infections

,

,

energy metabolism

,

ovarian epithelial carcinoma

,

head and neck neoplasms

,

stomach neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

neoplasms by site

,

non-small-cell lung carcinoma

,

,

,

falciparum malaria

,

ovarian neoplasms

,

renal cell carcinoma

,

,

healthy volunteers/patients

,

colorectal neoplasms

,

,

,

multiple myeloma

,

plasma cell neoplasms

,

pancreatic neoplasms

,

uterine cervical neoplasms

,

,

type 1 diabetes mellitus

,

sickle cell anemia

,

sjogren's syndrome

,

,

,

respiration disorders

,

chronic hepatitis b

,

,

endometrial neoplasms

,

,

malignant mesothelioma

,

squamous cell carcinoma of head and neck

,

cutaneous malignant melanoma

,

streptococcus agalactiae

,

follicular lymphoma

,

microsatellite repeats

,

small cell lung carcinoma

,

macular degeneration

,

b-cell lymphoma

,

,

,

respiratory tract diseases

,

,

focal segmental glomerulosclerosis

,

chronic hepatitis

,

membranous glomerulonephritis

,

nephrotic syndrome

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

systemic scleroderma

,

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

,

,

,

kidney transplantation

,

,

,

,

b-cell chronic lymphocytic leukemia

,

beta-thalassemia

,

,

sickle cell trait

,

,

,

clear cell adenocarcinoma

,

large cell carcinoma

,

vaginal neoplasms

,

vulvar neoplasms

,

adenomyoepithelioma

,

breast neoplasms

,

,

rheumatoid arthritis

,

,

haemophilus influenzae type b

,

haemophilus infections

,

chronic renal insufficiency

,

,

neisseria meningitidis

,

respiratory syncytial virus infections

,

streptococcal infections

,

,

muscle spasticity

,

kidney diseases

,

postmenopausal osteoporosis

,

non-hodgkin lymphoma

,

,

human influenza

,

,

insulin resistance

,

,

pneumococcal infections

,

thrombocytopenic purpura idiopathic

,

inflammatory breast neoplasms

,

,

ductal carcinoma breast

,

,

,

abdominal obesity

,

,

,

,

chronic kidney failure

,

,

large b-cell lymphoma diffuse

,

,

renal insufficiency

,

systemic lupus erythematosus

,

myocardial infarction

,

st elevation myocardial infarction

,

acute coronary syndrome

,

,

,

left ventricular hypertrophy

,

rotavirus infections

,

,

,

meningococcal infections

,

,

mucinous adenocarcinoma

,

,

meningococcal meningitis

,

,

thrombocytopenia

,

respiratory syncytial viruses

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

,

,

chronic obstructive pulmonary disease

,

acquired immunodeficiency syndrome

,

,

,

,

,

metabolic bone diseases

,

obstructive lung diseases

,

pulmonary eosinophilia

,

,

,

chronic bronchitis

,

,

chronic disease

,

growth and development

,

,

,

immunologic tests

,

,

alzheimer disease

,

cardiovascular diseases

,

wasting syndrome

,

,

lipid metabolism

,

resistance training

,

,

,

major depressive disorder

,

depressive disorder

,

,

allergic rhinitis seasonal

,

clostridioides difficile

Potassium magnesium citrate (4:1:2)

chronic renal insufficiency

,

kidney diseases

,

chronic kidney failure

,

,

hyperphosphatemia

healthy volunteers/patients

,

,

kidney diseases

,

retinal diseases

,

,

non-small-cell lung carcinoma

,

,

large-cell lymphoma anaplastic

,

respiratory syncytial virus infections

,

pulmonary arterial hypertension

,

breast neoplasms

,

,

endometrial neoplasms

,

,

brain neoplasms

,

gram-negative bacterial infections

,

urinary tract infections

,

bacterial infections

,

wound infection

,

,

bacterial pneumonia

,

infectious skin diseases

,

soft tissue infections

,

,

healthcare-associated pneumonia

,

,

nontuberculous mycobacterium infections

,

chronic bronchitis

,

,

,

,

,

,

mycobacterium infections

,

community-acquired infections

,

,

gram-positive bacterial infections

,

,

,

communicable diseases

,

intraabdominal infections

,

mycobacterium avium-intracellulare infection

,

mycobacterium avium complex

,

,

,

,

,

ventilator-associated pneumonia

,

methicillin-resistant staphylococcus aureus

,

,

acute necrotizing pancreatitis

,

community-acquired pneumonia

,

,

,

,

abdominal abscess

,

Potassium nitrate

muscular atrophy

,

spinal muscular atrophy

,

,

spinal muscular atrophies of childhood

,

,

lambert-eaton myasthenic syndrome

,

myasthenia gravis

,

congenital myasthenic syndromes

,

muscle weakness

long qt syndrome

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

,

therapeutic equivalency

,

alzheimer disease

,

torsades de pointes

,

,

cystic fibrosis

,

,

,

,

cardiovascular abnormalities

,

,

major depressive disorder

,

electrocardiography

,

drug interactions

,

,

,

,

,

,

psychotic disorders

,

renal cell carcinoma

,

,

,

coronary artery disease

,

human influenza

,

erectile dysfunction

,

,

polycythemia vera

,

duchenne muscular dystrophy

,

autoimmune diseases

,

orthostatic hypotension

,

migraine disorders

,

acute coronary syndrome

,

lecithin cholesterol acyltransferase deficiency

,

,

lice infestations

,

restless legs syndrome

,

depressive disorder

,

marijuana abuse

,

falciparum malaria

,

,

chronic hepatitis c

,

drug-related side effects and adverse reactions

,

allergic rhinitis

,

,

postoperative pain

,

hepatolenticular degeneration

,

overactive urinary bladder

,

,

acinetobacter infections

,

,

systemic lupus erythematosus

,

pulmonary arterial hypertension

,

,

,

embryo transfer

,

chronic renal insufficiency

,

renal insufficiency

,

,

premature obstetric labor

,

premature birth

,

amyotrophic lateral sclerosis

,

,

,

respiration disorders

,

,

,

,

,

rheumatoid arthritis

,

,

atrial fibrillation

,

atherosclerosis

,

human experimentation

,

myocardial ischemia

,

,

,

non-alcoholic fatty liver disease

,

alcoholic fatty liver

,

smoking cessation

,

multiple endocrine neoplasia type 1

,

postpartum hemorrhage

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

,

respiratory syncytial virus infections

,

retinal vein occlusion

,

,

choroidal neovascularization

,

,

pathologic neovascularization

,

sickle cell anemia

,

,

kidney diseases

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

pharmacokinetics

,

,

parkinson disease

,

pharmacological phenomena

,

,

,

,

,

,

,

,

h1n1 subtype influenza a virus

,

neoplasm metastasis

,

tobacco use disorder

,

,

anorexia nervosa

,

graft vs host disease

,

,

muscle spasticity

,

interstitial lung diseases

,

,

,

,

acquired immunodeficiency syndrome

,

community-acquired infections

,

extensively drug-resistant tuberculosis

,

,

,

,

bacterial pneumonia

,

,

breast neoplasms

,

mycobacterium infections

,

wounds and injuries

,

,

,

,

multiple myeloma

,

,

,

abdominal abscess

,

pelvic infection

,

,

myelodysplastic syndromes

,

myeloproliferative disorders

,

non-hodgkin lymphoma

,

congenital abnormalities

,

hodgkin disease

,

myelodysplastic-myeloproliferative diseases

,

plasma cell neoplasms

,

meningeal tuberculosis

,

phenylketonurias

,

respiratory tract diseases

,

mycobacterium tuberculosis

,

,

,

environmental biomarkers

,

,

infectious skin diseases

,

,

wound infection

,

triple negative breast neoplasms

,

aspiration pneumonia

,

,

,

myeloid leukemia acute

,

ovarian neoplasms

,

primary myelofibrosis

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

sezary syndrome

,

b-cell chronic lymphocytic leukemia

,

myelomonocytic leukemia chronic

,

leukemia myeloid chronic atypical bcr-abl negative

,

b-cell lymphoma marginal zone

,

follicular lymphoma

,

mantle-cell lymphoma

,

myeloid leukemia chronic-phase

,

large b-cell lymphoma diffuse

,

gestational trophoblastic disease

,

mycosis fungoides

,

myeloid leukemia accelerated phase

,

hairy cell leukemia

,

t-cell lymphoma cutaneous

,

testicular neoplasms

,

ovarian epithelial carcinoma

,

neutrophilic leukemia chronic

,

burkitt lymphoma

,

,

large-cell lymphoma immunoblastic

,

trophoblastic neoplasms

,

nervous system diseases

,

hereditary congenital and neonatal diseases and abnormalities

,

neural tube defects

,

nervous system malformations

,

spinal dysraphism

,

phacoemulsification

,

,

nontuberculous mycobacterium infections

,

acute cholecystitis

,

,

acanthamoeba keratitis

,

,

hidradenitis suppurativa

,

,

latent tuberculosis

,

disease susceptibility

,

prosthesis-related infections

,

lymph node tuberculosis

,

healthy volunteers/patients

,

,

pulmonary tuberculosis

,

,

,

,

multidrug-resistant tuberculosis

,

communicable diseases

,

chronic obstructive pulmonary disease

,

endophthalmitis

,

bacterial infections

,

community-acquired pneumonia

,

,

,

bacterial conjunctivitis

,

cataract extraction

,

,

chronic bronchitis

,

helicobacter infections

,

,

,

,

respiratory tract infections

,

,

obstructive lung diseases

,

intraabdominal infections

,

,

insulin resistance

,

disease progression

,

,

retinal detachment

,

macular degeneration

,

,

corneal diseases

,

contraception behavior

,

,

,

,

pelvic inflammatory disease

,

cardiovascular diseases

,

aggressive periodontitis

,

corneal transplantation

,

intraocular pressure

,

,

,

chronic periodontitis

,

maxillary sinusitis

,

,

microbial drug resistance

,

,

cardiac arrhythmias

,

soft tissue infections

,

bacterial endocarditis

,

,

,

pyogenic liver abscess

,

penetrating keratoplasty

,

,

,

patient preference

,

,

vision disorders

,

heart disease risk factors

,

glucose intolerance

,

,

,

,

intravitreal injections

,

patient compliance

,

,

metabolic syndrome

,

bacterial eye infections

,

penetrating eye injuries

,

,

corneal injuries

,

pulmonary infarction

,

gastroenteritis

,

,

pathologic dilatation

,

,

,

pneumococcal pneumonia

,

pneumococcal infections

,

urinary tract infections

,

aortic dissection

,

,

mycoplasma pneumonia

,

mycoplasma infections

,

pleuropneumonia

,

chemical and drug induced liver injury

,

venous thrombosis

,

,

bacterial skin diseases

,

bronchial diseases

,

,

precancerous conditions

,

,

,

,

,

dissociative disorders

,

,

,

postoperative complications

,

laboratory infection

,

hypersensitivity

,

body weight changes

,

appetitive behavior

,

feeding behavior

,

meibomian gland dysfunction

,

pleural empyema

Fluoroquinolone

healthy volunteers/patients

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