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Drug ReportsPipecuronium
Pipecuronium
Arduan (pipecuronium) is a small molecule pharmaceutical. Pipecuronium was first approved as Arduan on 1990-06-26.
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Events Timeline
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FDA approval date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Pipecuronium bromide
Tradename
Company
Number
Date
Products
ARDUANOrganonN-019638 DISCN1990-06-26
1 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
berinertBiologic Licensing Application2009-11-10
cinryzeBiologic Licensing Application2010-11-01
covaryxunapproved drug other2020-01-25
covaryx covaryxunapproved drug other2013-02-26
eemtunapproved drug other2020-01-22
eemt eemtunapproved drug other2013-03-01
esterified estrogens and methyltestosteroneunapproved drug other2025-02-10
esterified estrogens and methyltestosterone full strength esterified estrogens and methyltestosterone half strengthunapproved drug other2025-03-10
esterified estrogens and methytestesteroneunapproved drug other2022-11-25
estratest f.s.unapproved drug other2024-09-06
Show 18 more
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
M: Musculo-skeletal system drugs
M03: Muscle relaxants
M03A: Muscle relaxants, peripherally acting agents
M03AC: Other quaternary ammonium compounds in atc, muscle relaxants, peripherally acting
M03AC06: Pipecuronium bromide
HCPCS
No data
Clinical
Clinical Trials
548 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HypertriglyceridemiaD015228EFO_000421133149533
HypercholesterolemiaD0069371332532
Cardiovascular diseasesD002318EFO_0000319I985741329
Healthy volunteers/patients4121521
DyslipidemiasD05017131341021
Type 2 diabetes mellitusD003924EFO_0001360E1121231018
InflammationD007249MP_00018451423817
Diabetes mellitusD003920EFO_0000400E08-E131233816
HyperlipidemiasD006949EFO_0003774E78.51221116
AtherosclerosisD050197EFO_0003914I25.1124613
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
KetosisD007662R82.42412228
LeukemiaD007938C95721123
Myeloid leukemia acuteD015470C92.0418120
SyndromeD0135775153120
Heart failureD006333EFO_0003144I50434718
Myelodysplastic syndromesD009190D46415117
PreleukemiaD011289411113
ObesityD009765EFO_0001073E66.91211013
Wolman diseaseD015223Orphanet_75233E75.5152511
Non-small-cell lung carcinomaD0022893619
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LymphomaD008223C85.951415
Myeloid leukemiaD007951C9241415
NeoplasmsD009369C8051013
Breast neoplasmsD001943EFO_0003869C5068213
RecurrenceD01200851013
Non-hodgkin lymphomaD008228C85.93910
Hodgkin diseaseD006689C812910
CarcinomaD002277C80.0299
Myeloproliferative disordersD009196D47.1199
Multiple myelomaD009101C90.0199
Show 155 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AgingD000375GO_0007568R41.81156
VasoconstrictionD01466133
GlioblastomaD005909EFO_000051522
GliosarcomaD01831622
EczemaD004485L30.9112
Pleural diseasesD01099522
Pancreatic ductal carcinomaD02144111
Sickle cell anemiaD000755EFO_0000697D5711
Beta-thalassemiaD017086Orphanet_848D56.111
ThalassemiaD013789EFO_1001996D5611
Show 15 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
OverweightD050177E66.399
HypoxiaD000860R09.0277
Parkinson diseaseD010300EFO_0002508G2044
HepatitisD006505K75.933
Pediatric obesityD06376622
Weight lossD01543122
MenopauseD008593EFO_0003922N9522
Glucose intoleranceD018149HP_0000833R73.0322
Biological availabilityD00168222
Wasting syndromeD01928222
Show 99 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common namePipecuronium
INNpipecuronium bromide
Description
Pipecuronium bromide is a steroid ester.
Classification
Small molecule
Drug classquaternary ammonium derivatives: neuromuscular blocking agents; quaternary ammonium derivatives: neuromuscular blocking agents
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@H](CC[C@@]4(C)[C@H]3C[C@H](N3CC[N+](C)(C)CC3)[C@@H]4OC(C)=O)[C@@]2(C)C[C@@H]1N1CC[N+](C)(C)CC1
Identifiers
PDB
CAS-ID68399-58-6
RxCUI
ChEMBL IDCHEMBL1201206
ChEBI ID8230
PubChem CID65332
DrugBank
UNII IDR6ZTY81RE1 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
£
Cinryze Shire
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Cinryze Takeda
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Ruconest Pharming
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Tabular view
Estimated US medical usage
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 260,504 documents
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Safety
Black-box Warning
Black-box warning for: Covaryx, Covaryx covaryx, Eemt, Eemt eemt, Esterified estrogens and methyltestosterone, Esterified estrogens and methyltestosterone full strength esterified estrogens and methyltestosterone half strength, Esterified estrogens and methytestesterone, Estratest f.s., Estratest f.s. estratest h.s., Estratest fs estratest hs, Menest, Omega-3 rx complete, Omega-3 well pack
Adverse Events
Top Adverse Reactions
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23 adverse events reported
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