Lenomorelin
Lenomorelin is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
230 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | 7 | 3 | 4 | 6 | 60 | 77 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 5 | 3 | 1 | 1 | 15 | 22 |
| Healthy volunteers/patients | — | — | — | 7 | — | 1 | 1 | 8 | 17 |
| Overweight | D050177 | — | E66.3 | 1 | 1 | 1 | 1 | 14 | 17 |
| Feeding and eating disorders | D001068 | — | F50 | — | 1 | — | 1 | 4 | 6 |
| Bulimia | D002032 | — | F50.2 | — | 1 | — | 1 | 1 | 3 |
| Binge-eating disorder | D056912 | — | F50.2 | — | — | — | 1 | 1 | 2 |
| Critical illness | D016638 | — | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Insulin resistance | D007333 | EFO_0002614 | E88.819 | 2 | 2 | 2 | — | 12 | 16 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 3 | 3 | 1 | — | 11 | 15 |
| Weight loss | D015431 | — | — | — | 2 | 2 | — | 8 | 12 |
| Syndrome | D013577 | — | — | — | 1 | 3 | — | 9 | 12 |
| Prader-willi syndrome | D011218 | Orphanet_739 | Q87.11 | — | 1 | 3 | — | 7 | 10 |
| Morbid obesity | D009767 | EFO_0001074 | — | — | — | 1 | — | 5 | 6 |
| Body weight | D001835 | EFO_0004338 | — | — | — | 1 | — | 4 | 5 |
| Neoplasms | D009369 | — | C80 | 1 | 1 | 1 | — | 2 | 4 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | — | 1 | — | 3 | 4 |
| Hyperphagia | D006963 | — | R63.2 | — | 1 | 2 | — | 1 | 3 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alcoholism | D000437 | EFO_0003829 | F10.1 | 3 | 3 | — | — | 1 | 6 |
| Anorexia | D000855 | — | R63.0 | — | 1 | — | — | 5 | 6 |
| Frailty | D000073496 | — | R53.1 | 1 | 5 | — | — | — | 5 |
| Aging | D000375 | GO_0007568 | R41.81 | — | 1 | — | — | 3 | 4 |
| Motor activity | D009043 | EFO_0003940 | — | — | 1 | — | — | 2 | 3 |
| Cachexia | D002100 | — | R64 | 1 | 3 | — | — | — | 3 |
| Bulimia nervosa | D052018 | EFO_0005204 | F50.2 | — | 1 | — | — | 2 | 3 |
| Alcohol drinking | D000428 | EFO_0004329 | — | 2 | 2 | — | — | — | 3 |
| Major depressive disorder | D003865 | EFO_0003761 | F22 | 1 | 1 | — | — | 2 | 3 |
| Addictive behavior | D016739 | EFO_0004347 | — | 1 | 1 | — | — | — | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Endocrine system diseases | D004700 | EFO_0001379 | E34.9 | 1 | — | — | — | 1 | 2 |
| Smoking cessation | D016540 | EFO_0004319 | — | 1 | — | — | — | — | 1 |
| Gastric bypass | D015390 | EFO_0005244 | — | 1 | — | — | — | — | 1 |
| Metabolic bone diseases | D001851 | — | — | 1 | — | — | — | — | 1 |
| Alcohol-related disorders | D019973 | — | F10 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bariatric surgery | D050110 | — | — | — | — | — | — | 7 | 7 |
| Feeding behavior | D005247 | — | — | — | — | — | — | 6 | 6 |
| Appetitive behavior | D001070 | — | — | — | — | — | — | 5 | 5 |
| Anorexia nervosa | D000856 | EFO_0004215 | F50.0 | — | — | — | — | 5 | 5 |
| Pediatric obesity | D063766 | — | — | — | — | — | — | 4 | 4 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | — | — | — | 3 | 3 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | — | — | — | 3 | 3 |
| Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | — | — | — | — | 3 | 3 |
| Sleep deprivation | D012892 | — | F51.12 | — | — | — | — | 3 | 3 |
| Sleep | D012890 | GO_0030431 | — | — | — | — | — | 3 | 3 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Lenomorelin |
| INN | lenomorelin |
| Description | GHRELIN |
| Classification | Protein |
| Drug class | prehormones or hormone-release stimulating peptides |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL500468 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | UXG268Q86R (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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