Ghrelin
Ghrelin is a protein pharmaceutical. It is currently being investigated in clinical studies. It is known to target growth hormone secretagogue receptor type 1.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
No data
Clinical
Clinical Trials
229 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | 6 | 2 | 4 | 5 | 55 | 70 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 4 | 3 | 1 | 1 | 15 | 21 |
| Healthy volunteers/patients | — | — | — | 7 | — | 1 | 1 | 7 | 16 |
| Overweight | D050177 | — | E66.3 | — | — | 1 | 1 | 13 | 15 |
| Critical illness | D016638 | — | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | 3 | 3 | 1 | — | 11 | 15 |
| Insulin resistance | D007333 | HP_0000855 | — | 4 | 3 | 1 | — | 10 | 15 |
| Syndrome | D013577 | — | — | — | 1 | 3 | — | 9 | 12 |
| Weight loss | D015431 | HP_0001824 | — | — | — | 2 | — | 9 | 11 |
| Prader-willi syndrome | D011218 | Orphanet_739 | Q87.11 | — | 1 | 3 | — | 7 | 10 |
| Morbid obesity | D009767 | EFO_0001074 | — | — | — | 1 | — | 5 | 6 |
| Neoplasms | D009369 | — | C80 | 1 | 1 | 1 | — | 2 | 4 |
| Laron syndrome | D046150 | Orphanet_633 | E34.321 | — | 3 | 1 | — | — | 4 |
| Body weight | D001835 | EFO_0004338 | — | — | — | 1 | — | 3 | 4 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | — | 1 | — | 2 | 3 |
Show 2 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alcoholism | D000437 | EFO_0003829 | F10.1 | 3 | 3 | — | — | 1 | 6 |
| Endocrine system diseases | D004700 | EFO_0001379 | E34.9 | 1 | 3 | — | — | 1 | 5 |
| Aging | D000375 | GO_0007568 | R41.81 | 1 | 2 | — | — | 3 | 5 |
| Frailty | D000073496 | — | R53.1 | 1 | 4 | — | — | — | 4 |
| Feeding and eating disorders | D001068 | — | F50 | — | 1 | — | — | 3 | 4 |
| Pituitary dwarfism | D004393 | EFO_1001109 | E23.0 | — | 3 | — | — | — | 3 |
| Liver diseases | D008107 | HP_0002910 | K70-K77 | — | 1 | — | — | 2 | 3 |
| Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | — | 1 | — | — | 2 | 3 |
| Fatty liver | D005234 | EFO_0003934 | — | — | 1 | — | — | 2 | 3 |
| Chronic renal insufficiency | D051436 | — | N18 | — | 1 | — | — | 2 | 3 |
Show 23 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Smoking cessation | D016540 | EFO_0004319 | — | 1 | — | — | — | — | 1 |
| Gastric bypass | D015390 | EFO_0005244 | — | 1 | — | — | — | — | 1 |
| Metabolic bone diseases | D001851 | HP_0000938 | — | 1 | — | — | — | — | 1 |
| Sarcopenia | D055948 | EFO_1000653 | M62.84 | 1 | — | — | — | — | 1 |
| Alcohol-related disorders | D019973 | — | F10 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bariatric surgery | D050110 | — | — | — | — | — | — | 6 | 6 |
| Feeding behavior | D005247 | — | — | — | — | — | — | 6 | 6 |
| Anorexia | D000855 | HP_0002039 | R63.0 | — | — | — | — | 6 | 6 |
| Appetitive behavior | D001070 | — | — | — | — | — | — | 4 | 4 |
| Anorexia nervosa | D000856 | EFO_0004215 | F50.0 | — | — | — | — | 4 | 4 |
| Metabolic diseases | D008659 | EFO_0000589 | E88.9 | — | — | — | — | 3 | 3 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | — | — | — | 3 | 3 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | — | — | — | 3 | 3 |
| Pediatric obesity | D063766 | — | — | — | — | — | — | 3 | 3 |
| Appetite | D001066 | — | — | — | — | — | — | 3 | 3 |
Show 89 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Ghrelin |
| INN | lenomorelin |
| Description | GHRELIN |
| Classification | Protein |
| Drug class | prehormones or hormone-release stimulating peptides |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCCCCCC(=O)OC[C@H](NC(=O)CNC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)O |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL500468 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | UXG268Q86R (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 35,903 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use