Kineret(anakinra)
Kineret (anakinra) is a protein pharmaceutical. Anakinra was first approved as Kineret on 2001-11-14. It is used to treat cryopyrin-associated periodic syndromes and rheumatoid arthritis in the USA. It has been approved in Europe to treat rheumatoid arthritis.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Trade Name
FDA
EMA
Kineret
Drug Products
FDA
EMA
Reference product - 351(a)
Reference product - 351(a)
Interchangeable product - 351(k)
Interchangeable product - 351(k)
Biosimilar product - 351(k)
Biosimilar product - 351(k)
Anakinra
Tradename | Proper name | Company | Number | Date | Products |
|---|---|---|---|---|---|
| Kineret | anakinra | Orphan Medical | N-103950 RX | 2001-11-14 | 1 products |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| kineret | Biologic Licensing Application | 2024-09-20 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| rheumatoid arthritis | EFO_0000685 | D001172 | M06.9 |
| cryopyrin-associated periodic syndromes | — | D056587 | M04.2 |
Agency Specific
FDA
EMA
Expiration | Code | ||
|---|---|---|---|
anakinra, Kineret, Swedish Orphan Biovitrum AB (publ) | |||
| 2027-12-18 | Orphan excl. | ||
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
204 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Arthritis | D001168 | EFO_0005856 | M05-M14 | — | 6 | 2 | 3 | 7 | 17 |
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | 3 | 1 | 3 | 7 | 14 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 2 | 8 | 1 | 1 | — | 9 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 3 | — | 1 | 3 | 7 |
| Mucocutaneous lymph node syndrome | D009080 | EFO_0004246 | M30.3 | 2 | 2 | 1 | 1 | 1 | 6 |
| Sepsis | D018805 | EFO_0001420 | A41.9 | — | 3 | 2 | 1 | 1 | 6 |
| Recurrence | D012008 | — | — | 1 | 2 | — | 1 | 1 | 5 |
| Pericarditis | D010493 | EFO_0007427 | I30 | — | 1 | 1 | 1 | 2 | 5 |
| Hereditary autoinflammatory diseases | D056660 | — | — | — | — | 2 | 1 | — | 3 |
| Familial mediterranean fever | D010505 | — | M04.1 | — | — | 2 | 1 | — | 3 |
Show 6 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | U07.1 | — | 9 | 11 | — | 7 | 24 |
| Inflammation | D007249 | MP_0001845 | — | 5 | 12 | 1 | — | 5 | 18 |
| Syndrome | D013577 | — | — | 2 | 8 | 5 | — | 3 | 14 |
| Heart failure | D006333 | EFO_0003144 | I50 | 3 | 9 | 2 | — | 2 | 12 |
| Cytokine release syndrome | D000080424 | — | D89.83 | 1 | 7 | 4 | — | — | 9 |
| Infections | D007239 | EFO_0000544 | — | 1 | 5 | 2 | — | 3 | 9 |
| Coronavirus infections | D018352 | EFO_0007224 | B34.2 | — | 5 | 1 | — | 1 | 6 |
| Communicable diseases | D003141 | — | — | 1 | 3 | 1 | — | 2 | 6 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | 3 | 6 | 1 | — | — | 6 |
| Juvenile arthritis | D001171 | EFO_1002007 | M08 | — | 3 | 3 | — | 1 | 6 |
Show 42 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lymphoma | D008223 | — | C85.9 | — | 5 | — | — | — | 5 |
| Multiple myeloma | D009101 | — | C90.0 | 2 | 4 | — | — | — | 5 |
| Plasma cell neoplasms | D054219 | — | — | 2 | 4 | — | — | — | 5 |
| Acute lung injury | D055371 | EFO_0004610 | — | — | 1 | — | — | 3 | 4 |
| Newborn respiratory distress syndrome | D012127 | — | P22 | — | 1 | — | — | 3 | 4 |
| B-cell lymphoma | D016393 | — | — | — | 4 | — | — | — | 4 |
| Asthma | D001249 | EFO_0000270 | J45 | 3 | 3 | — | — | 1 | 4 |
| Macrophage activation syndrome | D055501 | EFO_1001806 | — | 1 | 3 | — | — | — | 4 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | 3 | — | — | 1 | 4 |
| Neurotoxicity syndromes | D020258 | — | G92 | 1 | 3 | — | — | — | 3 |
Show 93 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pain | D010146 | EFO_0003843 | R52 | 1 | — | — | — | 2 | 3 |
| Healthy volunteers/patients | — | — | — | 3 | — | — | — | — | 3 |
| Pulmonary arterial hypertension | D000081029 | — | — | 1 | — | — | — | 1 | 2 |
| Neoplasms | D009369 | — | C80 | 2 | — | — | — | — | 2 |
| Smoldering multiple myeloma | D000075122 | — | — | 1 | — | — | — | — | 1 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 1 | — | — | — | — | 1 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | — | — | — | — | 1 |
| Castration-resistant prostatic neoplasms | D064129 | — | — | 1 | — | — | — | — | 1 |
| Granuloma | D006099 | — | — | 1 | — | — | — | — | 1 |
| Chronic granulomatous disease | D006105 | EFO_0000338 | D71 | 1 | — | — | — | — | 1 |
Show 11 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Menorrhagia | D008595 | EFO_0003945 | N92.0 | — | — | — | — | 1 | 1 |
| Hemophilia a | D006467 | EFO_0007267 | D66 | — | — | — | — | 1 | 1 |
| Down syndrome | D004314 | EFO_0001064 | Q90 | — | — | — | — | 1 | 1 |
| Blood coagulation disorders | D001778 | EFO_0009314 | D68.9 | — | — | — | — | 1 | 1 |
| Hyperaldosteronism | D006929 | — | E26 | — | — | — | — | 1 | 1 |
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | — | — | — | — | 1 | 1 |
| Hyperphosphatemia | D054559 | — | — | — | — | — | — | 1 | 1 |
| Edema | D004487 | — | R60.9 | — | — | — | — | 1 | 1 |
| Hypokalemia | D007008 | — | E87.6 | — | — | — | — | 1 | 1 |
| Sleep initiation and maintenance disorders | D007319 | — | F51.01 | — | — | — | — | 1 | 1 |
Show 40 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Anakinra |
| INN | anakinra |
| Description | Interleukin-1 receptor antagonist protein precursor (IL-1ra) (IRAP) |
| Classification | Protein |
| Drug class | interleukin receptor antagonists: interleukin-1 (IL-1) receptor antagonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201570 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB00026 |
| UNII ID | 9013DUQ28K (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
No data
Estimated US medical usage
Anakinra
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 16,975 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
12,878 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use