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Company ReportsrEVO Biologics

rEVO Biologics

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Atryn	Antithrombin alfa	2009-02-06		Antithrombin iii deficiency

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Antithrombin alfa

congenital heart defects

,

postoperative hemorrhage

,

healthy volunteers/patients

,

,

,

,

liver cirrhosis

,

,

,

hepatic insufficiency

,

venous thromboembolism

,

thromboembolism

,

reperfusion injury

,

coronary artery bypass

,

respiratory distress syndrome

,

severe acute respiratory syndrome

,

acute lung injury

,

newborn respiratory distress syndrome

,

cardiac surgical procedures

,

hepatic veno-occlusive disease

,

end stage liver disease

,

,

acute-on-chronic liver failure

,

wounds and injuries

,

blood coagulation disorders

,

hemostatic disorders

,

venous thrombosis

,

cardiopulmonary bypass

,

disseminated intravascular coagulation

,

extracorporeal membrane oxygenation

,

,

antithrombin iii deficiency

,

,

,

,

,

myocardial infarction

,

,

acute coronary syndrome

,

aortic valve stenosis

,

aortic valve insufficiency

,

mitral valve insufficiency

,

mitral valve stenosis

,

,

coagulation protein disorders

,

,

congenital disorders of glycosylation

,

atrial fibrillation

,

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

sickle cell anemia

,

,

hemolytic anemia

,

,

thrombocytopenia

,

environmental biomarkers

,

,

,

,

factor xiii deficiency

,

migraine disorders

,

acute-phase reaction

,

antiphospholipid syndrome

,

,

,

cytokine release syndrome

,

,

upper extremity deep vein thrombosis

,

,

transfusion reaction

,

liver transplantation

,

,

heart septal defects

,

,

acute kidney injury

,

portal hypertension

,

,

budd-chiari syndrome

,

chronic renal insufficiency

,

post-acute covid-19 syndrome

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

neoplasm metastasis

,

hematologic neoplasms

,

healthy volunteers/patients

,

neurofibromatosis 1

,

neurofibrosarcoma

,

neurofibromatoses

,

nerve sheath neoplasms

,

breast neoplasms

,

non-small-cell lung carcinoma

alzheimer disease

,

macular degeneration

,

hepatic insufficiency

,

cognitive dysfunction

,

precursor cell lymphoblastic leukemia-lymphoma

,

maximum tolerated dose

,

antineoplastic protocols

,

pharmacokinetics

,

myeloproliferative disorders

,

type 1 diabetes mellitus

,

,

acquired immunodeficiency syndrome

,

,

,

immunologic deficiency syndromes

,

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

adenocarcinoma of lung

,

hematologic neoplasms

,

biliary liver cirrhosis

,

neonatal anemia

,

peripheral nervous system diseases

,

,

critical illness

,

gastrointestinal diseases

,

hidradenitis suppurativa

,

,

chronic hepatitis b

,

,

,

,

,

,

,

diffuse intrinsic pontine glioma

,

optic nerve glioma

,

brain stem neoplasms

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

pathologic complete response

,

,

sexually transmitted diseases

,

retroviridae infections

,

viral sexually transmitted diseases

,

pancreatic neoplasms

,

triple negative breast neoplasms

,

sickle cell anemia

,

immunoglobulin light-chain amyloidosis

,

healthy volunteers/patients

,

multiple myeloma

,

prostatic neoplasms

,

non-small-cell lung carcinoma

,

plasma cell neoplasms

,

large b-cell lymphoma diffuse

,

orthopedic procedures

,

rheumatoid arthritis

,

b-cell lymphoma

,

chronic renal insufficiency

,

blood transfusion

,

non-hodgkin lymphoma

,

psoriatic arthritis

,

,

mantle-cell lymphoma

,

kidney diseases

,

chronic kidney failure

,

systemic lupus erythematosus

,

follicular lymphoma

,

b-cell chronic lymphocytic leukemia

,

myelodysplastic syndromes

,

breast neoplasms

,

autologous blood transfusion

,

diabetes mellitus

,

,

ankylosing spondylitis

,

ovarian neoplasms

,

axial spondyloarthritis

,

,

lymphoid leukemia

,

renal insufficiency

,

,

neoplasm metastasis

,

cardiovascular surgical procedures

,

cerebrospinal fluid leak

,

peripheral vascular diseases

,

respiratory syncytial viruses

,

juvenile arthritis

,

waldenstrom macroglobulinemia

,

colorectal neoplasms

,

b-cell lymphoma marginal zone

,

,

,

retinal diseases

,

esophageal neoplasms

,

small cell lung carcinoma

,

,

venous thrombosis

,

stomach neoplasms

,

rectal neoplasms

,

,

diabetic neuropathies

,

,

,

ebola hemorrhagic fever

,

soft tissue injuries

,

surgical blood loss

,

neurologic manifestations

,

respiratory tract diseases

,

,

kidney transplantation

,

neonatal alloimmune thrombocytopenia

,

,

,

,

,

,

,

ulcerative colitis

,

,

type 2 diabetes mellitus

,

inflammatory bowel diseases

,

cardiovascular diseases

,

,

atrial fibrillation

,

metabolic syndrome

,

pure red-cell aplasia

,

postoperative pain

,

abdominal hernia

,

healthy volunteers/patients

,

,

ventilator-associated pneumonia

,

respiratory tract infections

,

meningococcal infections

,

pulmonary sarcoidosis

,

meningococcal meningitis

,

migraine disorders

,

,

headache disorders

,

,

,

borrelia infections

,

vector borne diseases

,

type 3 von willebrand disease

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