rEVO Biologics - PharmaKB

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rEVO Biologics

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Atryn	Antithrombin alfa	2009-02-06		Antithrombin iii deficiency

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Antithrombin alfa

congenital heart defects

,

postoperative hemorrhage

,

healthy volunteers/patients

,

,

,

,

liver cirrhosis

,

,

,

hepatic insufficiency

,

venous thromboembolism

,

thromboembolism

,

reperfusion injury

,

coronary artery bypass

,

respiratory distress syndrome

,

severe acute respiratory syndrome

,

acute lung injury

,

newborn respiratory distress syndrome

,

cardiac surgical procedures

,

hepatic veno-occlusive disease

,

end stage liver disease

,

,

acute-on-chronic liver failure

,

wounds and injuries

,

blood coagulation disorders

,

hemostatic disorders

,

venous thrombosis

,

cardiopulmonary bypass

,

disseminated intravascular coagulation

,

extracorporeal membrane oxygenation

,

,

antithrombin iii deficiency

,

,

,

,

,

myocardial infarction

,

,

acute coronary syndrome

,

aortic valve stenosis

,

aortic valve insufficiency

,

mitral valve insufficiency

,

mitral valve stenosis

,

,

coagulation protein disorders

,

,

congenital disorders of glycosylation

,

,

atrial fibrillation

,

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

sickle cell anemia

,

,

hemolytic anemia

,

,

thrombocytopenia

,

environmental biomarkers

,

,

,

,

factor xiii deficiency

,

migraine disorders

,

acute-phase reaction

,

antiphospholipid syndrome

,

,

,

cytokine release syndrome

,

,

upper extremity deep vein thrombosis

,

,

transfusion reaction

,

liver transplantation

,

,

heart septal defects

,

,

acute kidney injury

,

portal hypertension

,

,

budd-chiari syndrome

,

chronic renal insufficiency

,

post-acute covid-19 syndrome

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

peripheral arterial disease

,

venous thrombosis

,

atrial fibrillation

,

venous thromboembolism

,

,

pulmonary embolism

,

,

thromboembolism

,

,

coronary artery disease

breast neoplasms

,

hematologic neoplasms

,

,

neoplasm metastasis

,

pleural empyema

,

,

myocardial infarction

,

st elevation myocardial infarction

,

,

hematologic neoplasms

,

biphenotypic leukemia acute

,

b-cell leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

stomach neoplasms

,

myelodysplastic syndromes

,

,

muscle spasticity

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

,

,

b-cell lymphoma

,

ovarian neoplasms

,

,

b-cell lymphoma marginal zone

,

fallopian tube neoplasms

,

burkitt lymphoma

,

multiple myeloma

,

prostatic neoplasms

,

pancreatic neoplasms

,

triple negative breast neoplasms

,

esophageal neoplasms

,

squamous cell carcinoma of head and neck

,

reactive arthritis

,

waldenstrom macroglobulinemia

,

lymphoproliferative disorders

,

lymphatic diseases

,

intestinal neoplasms

,

colonic neoplasms

,

rectal neoplasms

,

,

,

,

neuroendocrine carcinoma

,

papillary thyroid cancer

,

,

primary myelofibrosis

,

,

hairy cell leukemia

,

abdominal hernia

,

,

breast neoplasms

,

urinary bladder neoplasms

,

uterine neoplasms

,

knee osteoarthritis

,

residual neoplasm

,

,

interstitial cystitis

,

neoadjuvant therapy

,

ovarian epithelial carcinoma

,

mantle-cell lymphoma

,

female genital neoplasms

,

peritoneal neoplasms

,

,

non-hodgkin lymphoma

,

,

non-small-cell lung carcinoma

,

b-cell chronic lymphocytic leukemia

,

,

myeloid leukemia acute

,

colorectal neoplasms

,

large b-cell lymphoma diffuse

,

follicular lymphoma

,

,

,

musculoskeletal diseases

,

ankylosing spondylitis

,

small cell lung carcinoma

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

inflammatory bowel diseases

,

macular degeneration

,

,

juvenile arthritis

,

neoplasm metastasis

,

,

papulosquamous skin diseases

,

wet macular degeneration

,

,

lymphoid leukemia

,

,

communicable diseases

,

bacterial infections

,

methicillin-resistant staphylococcus aureus

,

staphylococcal skin infections

,

infectious skin diseases

,

bacterial skin diseases

,

,

disease progression

,

,

parkinson disease

,

bronchopulmonary dysplasia

,

respiratory syncytial viruses

,

,

,

pyoderma gangrenosum

,

spondylarthropathies

,

spondylarthritis

,

spinal diseases

,

,

intermediate uveitis

,

posterior uveitis

,

precocious puberty

,

migraine disorders

,

retinal diseases

,

retinal degeneration

,

,

choroidal neovascularization

,

hepatocellular carcinoma

,

liver neoplasms

,

thyroid diseases

,

,

rheumatoid arthritis

,

,

,

ulcerative colitis

,

psoriatic arthritis

,

,

chronic hepatitis c

,

hidradenitis suppurativa

,

axial spondyloarthritis

,

cardiovascular diseases

,

connective tissue diseases

,

,

,

,

drug monitoring

,

coronary artery disease

,

myocardial ischemia

,

,

atherosclerosis

healthy volunteers/patients

breast neoplasms

,

stomach neoplasms

,

,

uterine cervical neoplasms

,

,

squamous cell carcinoma of head and neck

,

,

,

squamous cell carcinoma

,

oropharyngeal neoplasms

,

squamous cell neoplasms

,

penile neoplasms

,

adenosquamous carcinoma

,

vaginal neoplasms

,

vulvar neoplasms

,

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