rEVO Biologics - PharmaKB

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Company ReportsrEVO Biologics

rEVO Biologics

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Atryn	Antithrombin (recombinant)	2009-02-06		Antithrombin iii deficiency

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Antithrombin alfa

congenital heart defects

,

,

postoperative hemorrhage

,

healthy volunteers/patients

,

,

,

liver cirrhosis

,

wounds and injuries

,

,

,

,

hepatic insufficiency

,

venous thromboembolism

,

thromboembolism

,

,

,

reperfusion injury

,

coronary artery bypass

,

cerebral infarction

,

,

ischemic stroke

,

respiratory distress syndrome

,

severe acute respiratory syndrome

,

acute lung injury

,

newborn respiratory distress syndrome

,

hepatic veno-occlusive disease

,

,

small cell lung carcinoma

,

,

communicable diseases

,

end stage liver disease

,

acute-on-chronic liver failure

,

blood coagulation disorders

,

hemostatic disorders

,

cardiopulmonary bypass

,

disseminated intravascular coagulation

,

,

extracorporeal membrane oxygenation

,

type 1 diabetes mellitus

,

,

non-hodgkin lymphoma

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

antithrombin iii deficiency

,

,

,

venous thrombosis

,

,

myocardial infarction

,

,

cardiac surgical procedures

,

,

acute coronary syndrome

,

aortic valve stenosis

,

aortic valve insufficiency

,

mitral valve insufficiency

,

pathologic constriction

,

mitral valve stenosis

,

,

coagulation protein disorders

,

nutritional requirements

,

congenital disorders of glycosylation

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

sickle cell anemia

,

,

hemolytic anemia

,

,

thrombocytopenia

,

environmental biomarkers

,

,

,

,

factor xiii deficiency

,

migraine disorders

,

acute-phase reaction

,

antiphospholipid syndrome

,

,

cytokine release syndrome

,

,

upper extremity deep vein thrombosis

,

,

transfusion reaction

,

liver transplantation

,

,

heart septal defects

,

,

acute kidney injury

,

portal hypertension

,

,

budd-chiari syndrome

,

chronic renal insufficiency

,

kidney diseases

,

renal insufficiency

,

post-acute covid-19 syndrome

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

multi-infarct dementia

type 1 diabetes mellitus

,

type 2 diabetes mellitus

,

,

chronic hepatitis

,

liver cirrhosis

,

,

,

castration-resistant prostatic neoplasms

,

non-small-cell lung carcinoma

,

,

alzheimer disease

,

,

thyroid neoplasms

,

thyroid diseases

,

diabetes mellitus

,

,

,

chronic hepatitis c

,

,

,

acquired immunodeficiency syndrome

,

,

immunologic deficiency syndromes

,

small cell lung carcinoma

,

,

coronary artery disease

,

myocardial ischemia

,

,

atherosclerosis

,

rheumatoid arthritis

,

,

neuromuscular blockade

,

prostatic neoplasms

,

,

acute coronary syndrome

,

chronic renal insufficiency

,

kidney diseases

,

,

,

,

uterine prolapse

,

intestinal obstruction

,

,

spinal diseases

,

delayed emergence from anesthesia

,

,

,

muscle relaxation

,

,

,

,

,

urinary retention

,

,

female infertility

,

uterine diseases

,

postoperative complications

,

,

wound infection

,

surgical wound infection

Antithrombin iii

,

ischemic stroke

,

,

patent foramen ovale

,

atrial fibrillation

,

coronary artery disease

,

myocardial infarction

,

st elevation myocardial infarction

,

anterior wall myocardial infarction

,

,

inferior wall myocardial infarction

drug interactions

Sodium chloride

duchenne muscular dystrophy

,

muscular dystrophies

squamous cell carcinoma of head and neck

,

primary myelofibrosis

,

healthy volunteers/patients

,

uterine cervical neoplasms

,

cholangiocarcinoma

,

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

colorectal neoplasms

,

,

,

stomach neoplasms

,

b-cell lymphoma

,

triple negative breast neoplasms

,

large b-cell lymphoma diffuse

,

,

ovarian neoplasms

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

non-hodgkin lymphoma

,

ulcerative colitis

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

small cell lung carcinoma

,

ovarian epithelial carcinoma

,

neoplasm metastasis

,

,

,

,

,

peritoneal neoplasms

,

lupus nephritis

,

,

,

ductal carcinoma breast

,

macular degeneration

,

urinary bladder neoplasms

,

renal cell carcinoma

,

fallopian tube neoplasms

,

,

head and neck neoplasms

,

,

mucinous adenocarcinoma

,

inflammatory breast neoplasms

,

paroxysmal hemoglobinuria

,

,

pancreatic neoplasms

,

,

squamous cell carcinoma

,

urologic neoplasms

,

prostatic neoplasms

,

transitional cell carcinoma

,

colonic neoplasms

,

multiple sclerosis

,

,

,

,

wet macular degeneration

,

follicular lymphoma

,

systemic scleroderma

,

diffuse scleroderma

,

retinal vein occlusion

,

,

,

hemolytic-uremic syndrome

,

atypical hemolytic uremic syndrome

,

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

geographic atrophy

,

,

systemic lupus erythematosus

,

nephrotic syndrome

,

,

lipoid nephrosis

,

esophageal squamous cell carcinoma

,

esophageal neoplasms

,

castration-resistant prostatic neoplasms

,

retinal diseases

,

diabetic retinopathy

,

thyroid neoplasms

,

neuroendocrine carcinoma

,

papillary thyroid cancer

,

thyroid diseases

,

disease progression

,

endometrioid carcinoma

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

type 2 diabetes mellitus

,

diabetes mellitus

,

kidney diseases

,

membranous glomerulonephritis

,

chronic progressive multiple sclerosis

,

,

ankylosing spondylitis

,

spondylarthritis

,

,

residual neoplasm

,

myeloid leukemia acute

,

myeloid leukemia

,

alzheimer disease

,

coronary disease

,

acute coronary syndrome

,

coronary artery disease

,

myocardial ischemia

,

,

relapsing-remitting multiple sclerosis

,

guillain-barre syndrome

,

autoimmune diseases of the nervous system

,

hashimoto disease

,

,

partial epilepsies

,

bcr-abl positive chronic myelogenous leukemia

,

disability evaluation

,

cognition disorders

,

cytomegalovirus infections

,

,

hemolytic anemia autoimmune

,

hemolytic anemia

,

mantle-cell lymphoma

,

,

neoplasms by site

,

breast diseases

,

endometrial neoplasms

,

,

graft rejection

,

choroidal neovascularization

,

,

retinal neovascularization

,

pathologic neovascularization

,

human influenza

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

,

adenocarcinoma of lung

,

,

postmenopausal osteoporosis

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