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rEVO Biologics

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Atryn	Antithrombin alfa	2009-02-06		Antithrombin iii deficiency

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Antithrombin alfa

congenital heart defects

,

postoperative hemorrhage

,

healthy volunteers/patients

,

,

,

,

liver cirrhosis

,

,

,

hepatic insufficiency

,

thromboembolism

,

cardiac surgical procedures

,

reperfusion injury

,

coronary artery bypass

,

respiratory distress syndrome

,

severe acute respiratory syndrome

,

acute lung injury

,

newborn respiratory distress syndrome

,

hepatic veno-occlusive disease

,

end stage liver disease

,

,

acute-on-chronic liver failure

,

wounds and injuries

,

blood coagulation disorders

,

hemostatic disorders

,

venous thrombosis

,

cardiopulmonary bypass

,

disseminated intravascular coagulation

,

venous thromboembolism

,

,

extracorporeal membrane oxygenation

,

,

critical illness

,

coronary artery disease

,

percutaneous coronary intervention

,

dual anti-platelet therapy

,

antithrombin iii deficiency

,

,

,

,

,

myocardial infarction

,

,

acute coronary syndrome

,

aortic valve stenosis

,

aortic valve insufficiency

,

mitral valve insufficiency

,

mitral valve stenosis

,

,

coagulation protein disorders

,

congenital disorders of glycosylation

,

,

atrial fibrillation

,

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

sickle cell anemia

,

,

hemolytic anemia

,

,

thrombocytopenia

,

environmental biomarkers

,

,

,

,

factor xiii deficiency

,

migraine disorders

,

acute-phase reaction

,

antiphospholipid syndrome

,

,

,

cytokine release syndrome

,

,

upper extremity deep vein thrombosis

,

,

transfusion reaction

,

liver transplantation

,

,

heart septal defects

,

,

acute kidney injury

,

portal hypertension

,

,

budd-chiari syndrome

,

chronic renal insufficiency

,

post-acute covid-19 syndrome

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

chronic kidney failure

,

renal insufficiency

,

hemodiafiltration

,

disseminated intravascular coagulation

,

venous thromboembolism

,

thromboembolism

,

non-small-cell lung carcinoma

castration-resistant prostatic neoplasms

,

neurologic manifestations

,

glucose metabolism disorders

,

metabolic diseases

,

endocrine system diseases

,

,

pharmacokinetics

,

,

plexiform neurofibroma

,

neurofibromatosis 1

,

small cell carcinoma

,

urethral neoplasms

,

ureteral neoplasms

,

gastrointestinal neoplasms

,

,

male breast neoplasms

,

,

,

pancreatic neoplasms

,

,

,

,

esophageal neoplasms

,

,

brain neoplasms

,

malignant mesothelioma

,

liver neoplasms

,

squamous cell neoplasms

,

urinary bladder neoplasms

,

hepatocellular carcinoma

,

biliary tract neoplasms

,

prostatic neoplasms

,

healthy volunteers/patients

,

,

central nervous system diseases

,

myeloid leukemia acute

,

b-cell lymphoma

,

esophageal squamous cell carcinoma

,

,

,

mantle-cell lymphoma

,

aids-related opportunistic infections

,

parkinson disease

,

,

nervous system diseases

,

movement disorders

,

neurodegenerative diseases

,

hematologic neoplasms

,

cholangiocarcinoma

,

neoplasms by histologic type

,

,

urologic neoplasms

,

mouth neoplasms

,

oropharyngeal neoplasms

,

hypopharyngeal neoplasms

,

,

b-cell lymphoma marginal zone

,

epstein-barr virus infections

,

cutaneous malignant melanoma

,

kidney neoplasms

,

,

nasopharyngeal neoplasms

,

laryngeal neoplasms

,

renal insufficiency

,

,

,

oral candidiasis

,

pharyngeal diseases

,

infectious skin diseases

,

soft tissue infections

,

,

invasive hydatidiform mole

,

precursor cell lymphoblastic leukemia-lymphoma

,

primary myelofibrosis

,

,

chronic renal insufficiency

,

gallbladder neoplasms

,

,

nerve tissue neoplasms

,

neuroepithelial neoplasms

,

neuroectodermal tumors

,

bile duct neoplasms

,

,

neoplasms by site

,

glandular and epithelial neoplasms

,

basal cell carcinoma

,

merkel cell carcinoma

,

basal cell neoplasms

,

waldenstrom macroglobulinemia

,

central nervous system neoplasms

,

nervous system neoplasms

,

hematopoietic stem cell transplantation

,

endometrioid carcinoma

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

t-cell lymphoma cutaneous

,

,

myeloid leukemia

,

st elevation myocardial infarction

,

,

neuroendocrine tumors

,

local neoplasm recurrence

,

pancreatic ductal carcinoma

,

adenosquamous carcinoma

,

uveal neoplasms

,

non-small-cell lung carcinoma

,

breast neoplasms

,

colorectal neoplasms

,

,

squamous cell carcinoma of head and neck

,

,

triple negative breast neoplasms

,

,

ovarian neoplasms

,

uterine cervical neoplasms

,

renal cell carcinoma

,

,

large b-cell lymphoma diffuse

,

neoplasm metastasis

,

squamous cell carcinoma

,

stomach neoplasms

,

,

head and neck neoplasms

,

hodgkin disease

,

non-hodgkin lymphoma

,

small cell lung carcinoma

,

b-cell chronic lymphocytic leukemia

,

,

type 1 diabetes mellitus

,

follicular lymphoma

,

condylomata acuminata

,

endometrial neoplasms

,

fallopian tube neoplasms

,

,

transitional cell carcinoma

,

,

,

,

haemophilus infections

,

,

pneumococcal infections

,

,

rectal neoplasms

,

ulcerative colitis

,

,

,

psoriatic arthritis

,

,

,

,

bacterial infections

,

ovarian epithelial carcinoma

,

colonic neoplasms

,

multiple myeloma

,

plasma cell neoplasms

,

,

insulin resistance

,

vaginal neoplasms

,

vulvar neoplasms

,

kidney diseases

,

peritoneal neoplasms

,

staphylococcal infections

,

chronic hepatitis b

,

bcr-abl positive chronic myelogenous leukemia

,

axial spondyloarthritis

,

cervical intraepithelial neoplasia

,

uterine cervical dysplasia

,

,

,

,

,

,

respiratory syncytial virus infections

,

cardiovascular diseases

,

atherosclerosis

,

polycystic kidney diseases

,

assisted reproductive techniques

,

helping behavior

,

polymyalgia rheumatica

,

papillomaviridae

,

juvenile arthritis

,

spondylarthropathies

,

spondylarthritis

,

von hippel-lindau disease

,

type 2 diabetes mellitus

,

,

,

rheumatoid arthritis

,

,

diabetes mellitus

,

ankylosing spondylitis

,

acquired immunodeficiency syndrome

,

invasive candidiasis

,

chronic hepatitis c

,

,

papillomavirus infections

,

,

ovarian hyperstimulation syndrome

,

,

,

,

,

,

clostridium infections

,

acute coronary syndrome

,

,

hepatitis a virus

,

polycystic ovary syndrome

,

clostridioides difficile

,

hospitalization

,

,

human papillomavirus recombinant vaccine quadrivalent types 6 11 16 18

,

,

coronary artery disease

,

ebola hemorrhagic fever

,

,

esophageal diseases

,

neurotoxicity syndromes

,

embryo implantation

,

intestinal neoplasms

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

non-hodgkin lymphoma

,

extranodal nk-t-cell lymphoma

,

,

t-cell lymphoma

,

hodgkin disease

,

waldenstrom macroglobulinemia

,

b-cell lymphoma

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

t-cell lymphoma peripheral

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

nephrotic syndrome

,

focal segmental glomerulosclerosis

,

lipoid nephrosis

,

immunoglobulin g4-related disease

,

cardiac surgical procedures

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