rEVO Biologics - PharmaKB

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rEVO Biologics

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Atryn	Antithrombin alfa	2009-02-06		Antithrombin iii deficiency

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Antithrombin alfa

congenital heart defects

,

postoperative hemorrhage

,

healthy volunteers/patients

,

,

,

,

liver cirrhosis

,

,

,

hepatic insufficiency

,

venous thromboembolism

,

thromboembolism

,

reperfusion injury

,

coronary artery bypass

,

respiratory distress syndrome

,

severe acute respiratory syndrome

,

acute lung injury

,

newborn respiratory distress syndrome

,

cardiac surgical procedures

,

hepatic veno-occlusive disease

,

end stage liver disease

,

,

acute-on-chronic liver failure

,

wounds and injuries

,

blood coagulation disorders

,

hemostatic disorders

,

venous thrombosis

,

cardiopulmonary bypass

,

disseminated intravascular coagulation

,

extracorporeal membrane oxygenation

,

,

antithrombin iii deficiency

,

,

,

,

,

myocardial infarction

,

,

acute coronary syndrome

,

aortic valve stenosis

,

aortic valve insufficiency

,

mitral valve insufficiency

,

mitral valve stenosis

,

,

coagulation protein disorders

,

,

congenital disorders of glycosylation

,

,

atrial fibrillation

,

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

sickle cell anemia

,

,

hemolytic anemia

,

,

thrombocytopenia

,

environmental biomarkers

,

,

,

,

factor xiii deficiency

,

migraine disorders

,

acute-phase reaction

,

antiphospholipid syndrome

,

,

,

cytokine release syndrome

,

,

upper extremity deep vein thrombosis

,

,

transfusion reaction

,

liver transplantation

,

,

heart septal defects

,

,

acute kidney injury

,

portal hypertension

,

,

budd-chiari syndrome

,

chronic renal insufficiency

,

post-acute covid-19 syndrome

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

healthy volunteers/patients

,

factor vii deficiency

,

,

hidradenitis suppurativa

,

diffuse scleroderma

,

,

systemic scleroderma

,

rheumatoid arthritis

,

chronic obstructive pulmonary disease

,

soft tissue infections

,

necrotizing fasciitis

,

fournier gangrene

,

,

raynaud disease

,

wounds and injuries

,

myasthenia gravis

,

cardiac surgical procedures

,

,

eosinophilic esophagitis

,

postpartum hemorrhage

,

acute kidney injury

,

sickle cell anemia

,

acute chest syndrome

,

vaso-occlusive crises

,

,

agammaglobulinemia

,

common variable immunodeficiency

,

graft vs host disease

,

hereditary angioedemas

,

afibrinogenemia

,

blood coagulation disorders

,

ischemic stroke

,

,

coronary artery disease

,

,

heart valve diseases

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

kidney transplantation

,

,

von willebrand diseases

,

hemostatic disorders

,

postoperative hemorrhage

,

dermatomyositis

,

atrial fibrillation

,

,

,

cardiovascular diseases

,

acute coronary syndrome

,

hemorrhagic stroke

,

peripheral arterial disease

,

atherosclerosis

,

central nervous system diseases

,

central nervous system infections

,

encephalomyelitis

,

,

meningoencephalitis

,

acquired immunodeficiency syndrome

,

,

factor xiii deficiency

,

thrombocytopenia

,

,

primary immunodeficiency diseases

,

,

hereditary angioedema types i and ii

,

alpha 1-antitrypsin deficiency

,

surgical blood loss

,

immunologic deficiency syndromes

,

thrombocytopenic purpura idiopathic

,

,

cardiovascular surgical procedures

,

tropical spastic paraparesis

,

,

communicable diseases

,

thromboembolism

,

,

,

pneumococcal infections

,

,

streptococcal infections

,

bacterial pneumonia

,

,

bacterial meningitis

,

haemophilus influenzae

,

hereditary complement deficiency diseases

,

neisseriaceae infections

,

,

,

ataxia telangiectasia

,

,

x-linked combined immunodeficiency diseases

,

cerebellar ataxia

healthy volunteers/patients

,

,

type 2 diabetes mellitus

,

cytokine release syndrome

,

,

type 3 von willebrand disease

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