Nadide
Nadide is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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New Drug Application (NDA)
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FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| adstiladrin | Biologic Licensing Application | 2026-03-24 |
| as i am | C200263 | 2024-10-09 |
| co-bb-52549 featuring you hydrating skin enhancing tint spf30-375 strength co-bb-52816 featuring you hydrating skin enhancing tint spf30-390 achiev... | C200263 | 2024-04-01 |
| converthera nad plus patch | unapproved drug other | 2025-07-18 |
| detijian nadh | unapproved drug other | 2022-02-21 |
| enbrace hr | unapproved drug other | 2026-09-11 |
| enlyte | unapproved drug other | 2022-07-01 |
| nadolol | ANDA | 2026-09-07 |
| nadolol and bendroflumethiazide | ANDA | 2016-04-15 |
| numbuzin 9 nad bio super defense glow sunscreen broad spectrum spf 50 | C200263 | 2026-02-09 |
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Clinical
Clinical Trials
1293 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 61 | — | — | 1 | 8 | 70 |
| Diabetic neuropathies | D003929 | EFO_1000783 | — | 6 | 16 | 6 | 4 | 39 | 67 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 19 | 22 | 21 | 1 | 1 | 54 |
| Leukemia | D007938 | — | C95 | 13 | 19 | 16 | 1 | — | 41 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 7 | 5 | 2 | 2 | 15 | 30 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 13 | 4 | 2 | 2 | 9 | 28 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 12 | 5 | 1 | 1 | 9 | 27 |
| Covid-19 | D000086382 | — | U07.1 | 9 | 6 | 6 | 1 | 4 | 25 |
| Hypertension | D006973 | EFO_0000537 | I10 | 6 | 2 | 1 | 2 | 7 | 18 |
| Lymphoid leukemia | D007945 | — | C91 | 6 | 5 | 7 | 1 | — | 16 |
Show 78 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 84 | 19 | 5 | — | 8 | 101 |
| Colorectal neoplasms | D015179 | — | — | 51 | 30 | 15 | — | 6 | 84 |
| Rectal neoplasms | D012004 | — | — | 29 | 21 | 16 | — | 1 | 58 |
| Colonic neoplasms | D003110 | — | C18 | 29 | 19 | 19 | — | 1 | 57 |
| Lymphoma | D008223 | — | C85.9 | 19 | 21 | 12 | — | — | 44 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 27 | 13 | 4 | — | 4 | 38 |
| Peripheral nervous system diseases | D010523 | — | G64 | 1 | 10 | 5 | — | 22 | 36 |
| Adenocarcinoma | D000230 | — | — | 11 | 16 | 8 | — | 1 | 31 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 15 | 11 | 2 | — | 6 | 28 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 20 | 7 | 4 | — | 1 | 27 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lung neoplasms | D008175 | — | C34.90 | 12 | 7 | — | — | 1 | 16 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 7 | 4 | — | — | — | 10 |
| Melanoma | D008545 | — | — | 7 | 1 | — | — | 2 | 10 |
| Hodgkin disease | D006689 | — | C81 | 8 | 4 | — | — | — | 9 |
| Glioblastoma | D005909 | EFO_0000515 | — | 8 | 2 | — | — | — | 8 |
| Head and neck neoplasms | D006258 | — | — | 5 | 1 | — | — | 3 | 8 |
| Hematologic neoplasms | D019337 | — | — | 7 | 2 | — | — | — | 7 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | 7 | 2 | — | — | — | 7 |
| Plasma cell neoplasms | D054219 | — | — | 6 | 2 | — | — | — | 7 |
| Graft vs host disease | D006086 | — | D89.81 | 3 | 3 | — | — | 1 | 7 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | 9 | — | — | — | — | 9 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 7 | — | — | — | 1 | 8 |
| Anxiety disorders | D001008 | EFO_0006788 | F41.1 | 2 | — | — | — | 5 | 7 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 3 | — | — | — | 3 | 6 |
| Hyperlipidemias | D006949 | EFO_0003774 | E78.5 | 5 | — | — | — | — | 5 |
| Anxiety | D001007 | EFO_0005230 | F41.1 | 2 | — | — | — | 3 | 5 |
| Gastrointestinal stromal tumors | D046152 | EFO_0000505 | C49.A | 4 | — | — | — | — | 4 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | 4 | — | — | — | — | 4 |
| Substance-related disorders | D019966 | EFO_0003890 | F13 | 2 | — | — | — | 2 | 4 |
| Drug interactions | D004347 | — | — | 3 | — | — | — | — | 3 |
Show 115 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sleep initiation and maintenance disorders | D007319 | — | F51.01 | — | — | — | — | 14 | 14 |
| Chronic pain | D059350 | — | — | — | — | — | — | 5 | 5 |
| Post-traumatic stress disorders | D013313 | EFO_0001358 | F43.1 | — | — | — | — | 5 | 5 |
| Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | — | — | — | 4 | 4 |
| Mitochondrial myopathies | D017240 | Orphanet_206966 | G71.3 | — | — | — | — | 4 | 4 |
| Mental disorders | D001523 | EFO_0000677 | F91.9 | — | — | — | — | 4 | 4 |
| Parasomnias | D020447 | — | G47.5 | — | — | — | — | 4 | 4 |
| Healthy aging | D000073656 | — | — | — | — | — | — | 4 | 4 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | — | — | — | 3 | 3 |
| Autonomic nervous system diseases | D001342 | EFO_0009532 | G90 | — | — | — | — | 3 | 3 |
Show 234 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Nadide |
| INN | nadide |
| Description | Nicotinamide adenine dinucleotide (NAD) is a coenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine nucleobase and the other, nicotinamide. NAD exists in two forms: an oxidized and reduced form, abbreviated as NAD+ and NADH (H for hydrogen), respectively.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | NC(=O)c1ccc[n+]([C@@H]2O[C@H](COP(=O)([O-])OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)c1 |
Identifiers
| PDB | — |
| CAS-ID | 53-84-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1234613 |
| ChEBI ID | 44215 |
| PubChem CID | 925 |
| DrugBank | DB00157 |
| UNII ID | 0U46U6E8UK (ChemIDplus, GSRS) |
Target
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Trends
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Safety
Black-box Warning
Black-box warning for: Enlyte
Adverse Events
Top Adverse Reactions
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62,344 adverse events reported
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