Brand Name | Status | Last Update |
---|---|---|
adstiladrin | Biologic Licensing Application | 2024-08-12 |
corgard | New Drug Application | 2023-07-21 |
detijian nadh | unapproved drug other | 2022-02-21 |
enbrace hr | unapproved drug other | 2023-12-15 |
enlyte | unapproved drug other | 2022-07-01 |
nadolol | ANDA | 2024-07-30 |
nadolol and bendroflumethiazide | ANDA | 2016-04-15 |
paxlyte | unapproved drug other | 2024-08-01 |
wal-nadol pm | OTC monograph not final | 2023-09-13 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 41 | — | — | 1 | 6 | 48 |
Covid-19 | D000086382 | — | U07.1 | 7 | 6 | 3 | 1 | 4 | 20 |
Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | 9 | 3 | 2 | 1 | 4 | 18 |
Hypertension | D006973 | EFO_0000537 | I10 | 5 | 2 | 1 | 2 | 4 | 14 |
Breast neoplasms | D001943 | EFO_0003869 | C50 | 3 | 1 | — | 1 | 8 | 13 |
Infections | D007239 | EFO_0000544 | — | 4 | 1 | 2 | 3 | 3 | 12 |
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 5 | 1 | 1 | 1 | 3 | 11 |
Aging | D000375 | GO_0007568 | R41.81 | — | 3 | — | 1 | 4 | 8 |
Poliomyelitis | D011051 | EFO_0007450 | A80 | 4 | 2 | 3 | 1 | — | 8 |
Carcinoma | D002277 | — | C80.0 | 3 | 1 | — | 1 | 1 | 6 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hiv infections | D015658 | EFO_0000764 | B20 | 16 | 1 | 1 | — | 2 | 19 |
Lymphoma | D008223 | — | C85.9 | 12 | 6 | 1 | — | — | 15 |
Dyslipidemias | D050171 | HP_0003119 | — | 10 | — | 2 | — | — | 12 |
Syndrome | D013577 | — | — | 2 | 4 | 1 | — | 3 | 9 |
Hepatitis c | D006526 | — | B19.2 | 3 | 4 | 3 | — | 1 | 9 |
Hepatitis | D006505 | HP_0012115 | K75.9 | 2 | 6 | 3 | — | 1 | 9 |
Prostatic neoplasms | D011471 | — | C61 | 4 | 3 | 1 | — | 2 | 9 |
Hepatitis a | D006506 | EFO_0007305 | B15 | 2 | 6 | 3 | — | — | 8 |
Multiple myeloma | D009101 | — | C90.0 | 4 | 3 | 1 | — | 1 | 8 |
Colorectal neoplasms | D015179 | — | — | 3 | — | 1 | — | 3 | 7 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | 25 | 12 | — | — | 4 | 33 |
Leukemia | D007938 | — | C95 | 7 | 5 | — | — | — | 10 |
Depression | D003863 | — | F33.9 | — | 1 | — | — | 9 | 10 |
Stomach neoplasms | D013274 | EFO_0003897 | C16 | 2 | 1 | — | — | 6 | 8 |
Non-small-cell lung carcinoma | D002289 | — | — | 8 | 3 | — | — | — | 8 |
Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 5 | 1 | — | — | 3 | 8 |
Cognitive dysfunction | D060825 | HP_0001268 | G31.84 | 2 | 2 | — | — | 6 | 8 |
Heart failure | D006333 | HP_0001635 | I50 | 3 | 4 | — | — | 3 | 8 |
Lung neoplasms | D008175 | HP_0100526 | C34.90 | 4 | 7 | — | — | — | 7 |
Depressive disorder | D003866 | EFO_1002014 | F32.A | — | 1 | — | — | 6 | 7 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | 7 | — | — | — | — | 7 |
Glioblastoma | D005909 | EFO_0000515 | — | 5 | — | — | — | — | 5 |
Head and neck neoplasms | D006258 | — | — | 2 | — | — | — | 3 | 5 |
Pregnancy | D011247 | EFO_0002950 | Z33.1 | 4 | — | — | — | — | 4 |
Hyperlipidemias | D006949 | HP_0003077 | E78.5 | 4 | — | — | — | — | 4 |
Melanoma | D008545 | — | — | 2 | — | — | — | 2 | 4 |
Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 1 | — | — | — | 3 | 4 |
Uterine cervical neoplasms | D002583 | HP_0030159 | — | 2 | — | — | — | 2 | 4 |
T-cell lymphoma | D016399 | — | — | 3 | — | — | — | — | 3 |
Follicular lymphoma | D008224 | — | C82 | 3 | — | — | — | — | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sleep initiation and maintenance disorders | D007319 | — | F51.01 | — | — | — | — | 11 | 11 |
Chronic pain | D059350 | HP_0012532 | — | — | — | — | — | 5 | 5 |
Mental disorders | D001523 | EFO_0000677 | F91.9 | — | — | — | — | 4 | 4 |
Post-traumatic stress disorders | D013313 | EFO_0001358 | F43.1 | — | — | — | — | 4 | 4 |
Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | — | 4 | 4 |
Chronic disease | D002908 | — | — | — | — | — | — | 4 | 4 |
Heart diseases | D006331 | EFO_0003777 | I51.9 | — | — | — | — | 3 | 3 |
Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | — | — | — | 3 | 3 |
Mitochondrial myopathies | D017240 | Orphanet_206966 | G71.3 | — | — | — | — | 3 | 3 |
Psychotic disorders | D011618 | — | F20.81 | — | — | — | — | 3 | 3 |
Drug common name | Nadide |
INN | nadide |
Description | Nicotinamide adenine dinucleotide (NAD) is a coenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine nucleobase and the other, nicotinamide. NAD exists in two forms: an oxidized and reduced form, abbreviated as NAD+ and NADH (H for hydrogen), respectively.
|
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | NC(=O)c1ccc[n+]([C@@H]2O[C@H](COP(=O)([O-])OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)c1 |
PDB | — |
CAS-ID | 53-84-9 |
RxCUI | — |
ChEMBL ID | CHEMBL1234613 |
ChEBI ID | 44215 |
PubChem CID | 925 |
DrugBank | DB00157 |
UNII ID | 0U46U6E8UK (ChemIDplus, GSRS) |