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Trade Name	Drug Name	Approved	Patent Expires	Indication
Corgard	Nadolol	1982-01-01		Heart failure , Hypertension , Myocardial infarction , Angina pectoris , Nephrotic syndrome , Edema
Lucemyra	Lofexidine	2018-05-16		Substance withdrawal syndrome
Melphalan	Melphalan	2019-05-03	2029-2036	Myeloid leukemia acute , Breast neoplasms , Ovarian neoplasms , Non-hodgkin lymphoma , Multiple myeloma , Neuroblastoma , Precursor cell lymphoblastic leukemia-lymphoma , Hematopoietic stem cell transplantation , Hodgkin disease , Rhabdomyosarcoma
Revonto	Dantrolene	2007-07-24	2025	Multiple sclerosis, Spinal cord injuries, Cerebral infarction, Muscle spasticity, Cerebral palsy, Malignant hyperthermia, Neuroleptic malignant syndrome

Clinical Trials

Therapeutic Areas:

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Classification:

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Approval:

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Status:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

AFAMITRESGENE AUTOLEUCEL

ovarian neoplasms

,

non-small-cell lung carcinoma

,

stomach neoplasms

,

head and neck neoplasms

,

esophageal neoplasms

,

urinary bladder neoplasms

,

,

,

synovial sarcoma

,

myxoid liposarcoma

,

,

,

,

neurofibrosarcoma

migraine disorders

,

precursor cell lymphoblastic leukemia-lymphoma

,

hepatic insufficiency

,

,

,

transplantation

,

dermatomyositis

,

,

central nervous system neoplasms

,

germ cell and embryonal neoplasms

,

liver neoplasms

,

nervous system neoplasms

,

dna repair-deficiency disorders

,

hereditary congenital and neonatal diseases and abnormalities

,

,

hypoplastic anemia congenital

,

hemic and lymphatic diseases

,

adenosquamous carcinoma

,

thoracic neoplasms

,

esophageal neoplasms

,

,

squamous cell carcinoma of head and neck

,

,

,

kidney neoplasms

,

bites and stings

,

pancreatic neoplasms

,

ovarian neoplasms

,

castration-resistant prostatic neoplasms

,

myeloid leukemia acute

,

renal cell carcinoma

,

graft vs host disease

,

carcinoid tumor

,

type 1 diabetes mellitus

,

invasive hydatidiform mole

,

myeloid leukemia

,

,

,

acquired immunodeficiency syndrome

,

,

,

b-cell lymphoma

,

smoldering multiple myeloma

,

gastrointestinal neoplasms

,

urinary bladder neoplasms

,

,

,

uterine neoplasms

,

female genital neoplasms

,

hematopoietic stem cell transplantation

,

thyroid neoplasms

,

endocrine gland neoplasms

,

parathyroid neoplasms

,

,

giant cell tumors

,

,

second primary neoplasms

,

chronic urticaria

,

parkinson disease

,

aplastic anemia

,

mucocutaneous lymph node syndrome

,

fallopian tube neoplasms

,

,

urologic neoplasms

,

transitional cell carcinoma

,

ureteral neoplasms

,

serotonin syndrome

,

malignant pleural effusion

,

circulating neoplastic cells

,

myelomonocytic leukemia juvenile

,

bcr-abl positive chronic myelogenous leukemia

,

,

replacement arthroplasty hip

,

,

aneurysmal bone cysts

,

giant cell granuloma

,

,

chondroblastoma

,

deglutition disorders

,

,

brain neoplasms

,

kidney transplantation

,

graft rejection

,

psychology rejection

,

triple negative breast neoplasms

,

,

,

breast neoplasms

,

non-small-cell lung carcinoma

,

neoplasm metastasis

,

multiple myeloma

,

rectal neoplasms

,

,

colonic neoplasms

,

head and neck neoplasms

,

plasma cell neoplasms

,

,

non-hodgkin lymphoma

,

prostatic neoplasms

,

hematologic neoplasms

,

myelodysplastic syndromes

,

,

,

stomach neoplasms

,

,

,

,

,

squamous cell neoplasms

,

,

,

,

,

squamous cell carcinoma

,

,

hodgkin disease

,

follicular lymphoma

,

large b-cell lymphoma diffuse

,

juvenile arthritis

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

thrombocytopenic purpura

,

,

mucinous adenocarcinoma

,

,

,

small cell lung carcinoma

,

b-cell chronic lymphocytic leukemia

,

hematologic diseases

,

,

spinal cord compression

,

,

hypercholesterolemia

,

inflammatory breast neoplasms

,

,

metabolic diseases

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

ankylosing spondylitis

,

spondylarthropathies

,

spondylarthritis

,

,

febrile neutropenia

,

cardiovascular diseases

,

ventricular dysfunction

,

sezary syndrome

,

precancerous conditions

,

lymphoproliferative disorders

,

prolymphocytic leukemia

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

immunoglobulin light-chain amyloidosis

,

large granular lymphocytic leukemia

,

large-cell lymphoma immunoblastic

,

monoclonal gammopathy of undetermined significance

,

osteogenesis imperfecta

,

musculoskeletal diseases

,

blood protein disorders

,

bone marrow diseases

,

paraproteinemias

,

neoplastic processes

,

multiple endocrine neoplasia type 1

,

,

personal satisfaction

,

,

hyperlipoproteinemia type ii

,

ductal carcinoma breast

,

hemostatic disorders

,

critical illness

,

,

,

laryngeal diseases

,

,

esophageal squamous cell carcinoma

,

phenylketonurias

,

feeding and eating disorders

,

anorexia nervosa

,

,

,

,

colorectal neoplasms

,

,

,

chronic renal insufficiency

,

rheumatoid arthritis

,

kidney diseases

,

metabolic bone diseases

,

postmenopausal osteoporosis

,

,

,

healthy volunteers/patients

,

psoriatic arthritis

,

chronic kidney failure

,

renal insufficiency

,

giant cell tumor of bone

,

,

,

,

,

erythrocyte transfusion

,

primary hyperparathyroidism

,

,

,

,

autoimmune diseases

,

,

aids-related complex

,

cardiomyopathies

,

,

hyperlipidemias

,

diabetes mellitus

,

insulin resistance

,

metabolic syndrome

,

microvascular angina

,

atherosclerosis

,

hidradenitis suppurativa

LETETRESGENE AUTOLEUCEL

multiple myeloma

,

plasma cell neoplasms

,

,

non-small-cell lung carcinoma

,

,

,

synovial sarcoma

Globulin, immune

healthy volunteers/patients

,

,

hodgkin disease

,

squamous cell neoplasms

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

hematologic neoplasms

,

alzheimer disease

,

,

,

urologic neoplasms

,

transitional cell carcinoma

,

,

triple negative breast neoplasms

,

,

pancreatic neoplasms

,

small cell lung carcinoma

,

squamous cell carcinoma

,

prostatic neoplasms

,

fallopian tube neoplasms

,

pancreatic ductal carcinoma

,

rheumatoid arthritis

,

uterine cervical neoplasms

,

b-cell lymphoma marginal zone

,

waldenstrom macroglobulinemia

,

multiple myeloma

,

brain neoplasms

,

lymphoid leukemia

,

,

rectal neoplasms

,

esophageal squamous cell carcinoma

,

cholangiocarcinoma

,

,

serous cystadenocarcinoma

,

hereditary breast and ovarian cancer syndrome

,

diabetes mellitus

,

type 1 diabetes mellitus

,

insulin resistance

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

ulcerative colitis

,

,

,

small cell carcinoma

,

castration-resistant prostatic neoplasms

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

epstein-barr virus infections

,

oropharyngeal neoplasms

,

,

,

peripheral nervous system diseases

,

,

residual neoplasm

,

adenocarcinoma of lung

,

precursor cell lymphoblastic leukemia-lymphoma

,

biphenotypic leukemia acute

,

burkitt lymphoma

,

merkel cell carcinoma

,

clostridium infections

,

colonic neoplasms

,

non-small-cell lung carcinoma

,

,

colorectal neoplasms

,

neoplasm metastasis

,

,

ovarian neoplasms

,

stomach neoplasms

,

,

squamous cell carcinoma of head and neck

,

non-hodgkin lymphoma

,

,

b-cell lymphoma

,

hepatocellular carcinoma

,

liver neoplasms

,

endometrial neoplasms

,

,

large b-cell lymphoma diffuse

,

mantle-cell lymphoma

,

renal cell carcinoma

,

urinary bladder neoplasms

,

biliary tract neoplasms

,

head and neck neoplasms

,

,

follicular lymphoma

,

esophageal neoplasms

,

malignant mesothelioma

,

,

respiratory syncytial virus infections

,

,

uterine neoplasms

,

,

,

,

gastrointestinal neoplasms

,

respiratory tract infections

,

lymphoproliferative disorders

,

kidney neoplasms

,

laryngeal diseases

,

breast diseases

,

type 2 diabetes mellitus

,

,

inflammatory bowel diseases

,

,

human influenza

,

eosinophilic esophagitis

,

,

,

gastroenteritis

,

coronavirus infections

,

,

hematologic diseases

,

hypereosinophilic syndrome

,

leukocyte disorders

,

exercise-induced asthma

,

neuromyelitis optica

,

gallbladder neoplasms

,

breast neoplasms

,

,

systemic lupus erythematosus

,

b-cell chronic lymphocytic leukemia

,

ovarian epithelial carcinoma

,

b-cell leukemia

,

lymphatic diseases

,

pulmonary eosinophilia

,

,

immunologic deficiency syndromes

,

,

,

respiratory syncytial viruses

,

female genital neoplasms

,

myasthenia gravis

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

myelodysplastic syndromes

,

lymphoid leukemia

,

thoracic neoplasms

,

neurologic manifestations

,

papillomaviridae

,

pharmacokinetics

,

soft tissue neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

respiratory tract neoplasms

,

bronchogenic carcinoma

,

endocrine gland neoplasms

,

breast diseases

,

bronchial neoplasms

,

intraductal carcinoma noninfiltrating

,

laryngeal diseases

,

,

oligodendroglioma

,

oral administration

,

,

pancreatic neoplasms

,

,

brain neoplasms

,

castration-resistant prostatic neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

non-hodgkin lymphoma

,

myeloid leukemia acute

,

follicular lymphoma

,

,

t-cell lymphoma

,

kidney neoplasms

,

neuroendocrine tumors

,

pancreatic ductal carcinoma

,

uveal neoplasms

,

,

invasive hydatidiform mole

,

colonic neoplasms

,

neuroendocrine carcinoma

,

t-cell lymphoma peripheral

,

,

thyroid neoplasms

,

myeloid leukemia

,

urethral neoplasms

,

uterine neoplasms

,

microsatellite instability

,

cutaneous malignant melanoma

,

gastrointestinal neoplasms

,

mouth neoplasms

,

oropharyngeal neoplasms

,

small cell carcinoma

,

b-cell lymphoma marginal zone

,

,

female genital neoplasms

,

hypersensitivity

,

,

epstein-barr virus infections

,

microsatellite repeats

,

rectal neoplasms

,

hypopharyngeal neoplasms

,

salivary gland neoplasms

,

endometrioid carcinoma

,

vulvar neoplasms

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

non-muscle invasive bladder neoplasms

,

penile neoplasms

,

neoplasms by histologic type

,

,

b-cell chronic lymphocytic leukemia

,

t-cell lymphoma cutaneous

,

ureteral neoplasms

,

,

,

,

thymus neoplasms

,

burkitt lymphoma

,

laryngeal neoplasms

,

,

adenoid cystic carcinoma

,

,

serous cystadenocarcinoma

,

glandular and epithelial neoplasms

,

male breast neoplasms

,

,

adenocarcinoma of lung

,

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

mycosis fungoides

,

,

pelvic neoplasms

,

central nervous system neoplasms

,

germ cell and embryonal neoplasms

,

digestive system neoplasms

,

basal cell carcinoma

,

reactive arthritis

,

,

adenosquamous carcinoma

,

gestational trophoblastic disease

,

alveolar soft part sarcoma

,

biphenotypic leukemia acute

,

local neoplasm recurrence

,

,

,

meningeal carcinomatosis

,

immunoblastic lymphadenopathy

,

enteropathy-associated t-cell lymphoma

,

,

carcinoma in situ

,

cervical intraepithelial neoplasia

,

uterine cervical dysplasia

,

squamous intraepithelial lesions of the cervix

,

disease progression

,

central nervous system diseases

,

extranodal nk-t-cell lymphoma

,

neoplasms by site

,

x-linked bulbo-spinal atrophy

,

malignant fibrous histiocytoma

,

nasopharyngeal carcinoma

,

,

,

unknown primary neoplasms

,

synovial sarcoma

,

,

oral leukoplakia

,

,

hematologic diseases

,

bone marrow diseases

,

,

sezary syndrome

,

,

colonic diseases

,

histiocytic sarcoma

,

follicular dendritic cell sarcoma

,

interdigitating dendritic cell sarcoma

,

environmental biomarkers

,

circulating neoplastic cells

,

inflammatory breast neoplasms

,

meningeal neoplasms

,

intestinal neoplasms

,

nervous system neoplasms

,

kidney diseases

,

nervous system diseases

,

nerve tissue neoplasms

,

neuroepithelial neoplasms

,

neuroectodermal tumors

,

anaplastic thyroid carcinoma

,

thyroid diseases

,

adrenocortical carcinoma

,

carcinoid tumor

,

parotid neoplasms

,

mediastinal neoplasms

,

testicular neoplasms

,

male genital neoplasms

,

gastrointestinal stromal tumors

,

hairy cell leukemia

,

spinal cord neoplasms

,

acinar cell carcinoma

,

adenoviridae infections

,

,

hereditary breast and ovarian cancer syndrome

,

mullerian mixed tumor

,

basal cell neoplasms

,

urogenital neoplasms

,

male urogenital diseases

,

hemangiosarcoma

,

perivascular epithelioid cell neoplasms

,

,

,

,

breast neoplasms

,

triple negative breast neoplasms

,

colorectal neoplasms

,

renal cell carcinoma

,

squamous cell carcinoma

,

ovarian neoplasms

,

neoplasm metastasis

,

head and neck neoplasms

,

stomach neoplasms

,

urinary bladder neoplasms

,

,

prostatic neoplasms

,

,

liver neoplasms

,

hepatocellular carcinoma

,

esophageal neoplasms

,

endometrial neoplasms

,

uterine cervical neoplasms

,

transitional cell carcinoma

,

small cell lung carcinoma

,

hodgkin disease

,

urologic neoplasms

,

fallopian tube neoplasms

,

,

multiple myeloma

,

squamous cell neoplasms

,

ovarian epithelial carcinoma

,

,

biliary tract neoplasms

,

esophageal squamous cell carcinoma

,

cholangiocarcinoma

,

plasma cell neoplasms

,

,

malignant mesothelioma

,

peritoneal neoplasms

,

merkel cell carcinoma

,

nasopharyngeal neoplasms

,

bile duct neoplasms

,

gallbladder neoplasms

,

hematologic neoplasms

,

non-small-cell lung carcinoma

,

,

squamous cell carcinoma of head and neck

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