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Company ReportsStemline Therapeutics

Stemline Therapeutics(STML)

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Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Elzonris	Tagraxofusp	2018-12-21		Lymphoma , Malignant histiocytic disorders
Nexpovio	Selinexor	2021-03-26	2032-2035	Multiple myeloma
Orserdu	Elacestrant	2023-01-27	2024-2038	Breast neoplasms

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

myelodysplastic syndromes

,

,

,

blastic plasmacytoid dendritic cell neoplasm

,

,

myeloid leukemia acute

,

myeloid leukemia

,

,

multiple myeloma

,

plasma cell neoplasms

,

primary myelofibrosis

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia acute

,

myelomonocytic leukemia juvenile

,

diffuse intrinsic pontine glioma

,

parkinson disease

,

,

,

,

acquired immunodeficiency syndrome

,

,

connective tissue diseases

,

immune system diseases

,

rheumatic diseases

,

,

musculoskeletal diseases

,

collagen diseases

,

breast carcinoma in situ

,

leukemia myeloid chronic atypical bcr-abl negative

,

plasma cell leukemia

,

primary myelofibrosis

,

fallopian tube diseases

,

basal cell neoplasms

,

brain stem neoplasms

,

stem cell transplantation

,

hereditary breast and ovarian cancer syndrome

,

adenocarcinoma of lung

,

waldenstrom macroglobulinemia

,

paraproteinemias

,

precancerous conditions

,

smoldering multiple myeloma

,

mycobacterium avium-intracellulare infection

,

,

carcinoid tumor

,

healthy volunteers/patients

,

respiratory syncytial virus infections

,

,

,

phenylketonurias

,

myasthenia gravis

,

muscle weakness

,

acinar cell carcinoma

,

conjunctival neoplasms

,

,

clear cell sarcoma

,

gastrointestinal stromal tumors

,

salivary gland neoplasms

,

testicular neoplasms

,

breast diseases

,

medullary carcinoma

,

mammary paget's disease

,

thrombocytopenia

,

paroxysmal hemoglobinuria

,

,

,

parkinsonian disorders

,

pharmacokinetics

,

lymphatic metastasis

,

ovarian neoplasms

,

colorectal neoplasms

,

,

ovarian epithelial carcinoma

,

liver neoplasms

,

,

neoplasm metastasis

,

b-cell chronic lymphocytic leukemia

,

myeloproliferative disorders

,

hodgkin disease

,

fallopian tube neoplasms

,

kidney neoplasms

,

central nervous system neoplasms

,

nervous system neoplasms

,

b-cell lymphoma

,

brain neoplasms

,

myelomonocytic leukemia juvenile

,

myelodysplastic-myeloproliferative diseases

,

,

,

stomach neoplasms

,

rheumatoid arthritis

,

peritoneal neoplasms

,

myelomonocytic leukemia chronic

,

hematologic neoplasms

,

respiratory distress syndrome

,

,

colonic neoplasms

,

malignant mesothelioma

,

,

oligodendroglioma

,

rectal neoplasms

,

male breast neoplasms

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

,

,

ductal carcinoma

,

squamous cell carcinoma of head and neck

,

esophageal neoplasms

,

aplastic anemia

,

t-cell lymphoma

,

drug-related side effects and adverse reactions

,

,

merkel cell carcinoma

,

,

uterine cervical neoplasms

,

acute lung injury

,

newborn respiratory distress syndrome

,

myeloid leukemia chronic-phase

,

,

inflammatory breast neoplasms

,

invasive hydatidiform mole

,

t-cell lymphoma peripheral

,

mantle-cell lymphoma

,

,

,

t-cell lymphoma cutaneous

,

myelomonocytic leukemia acute

,

castration-resistant prostatic neoplasms

,

alzheimer disease

,

endometrial neoplasms

,

peripheral arterial disease

,

peripheral vascular diseases

,

mycobacterium infections

,

intraductal carcinoma noninfiltrating

,

respiratory aspiration

,

multiple sclerosis

,

small cell lung carcinoma

,

alveolar soft part sarcoma

,

nasopharyngeal carcinoma

,

burkitt lymphoma

,

immunoglobulin light-chain amyloidosis

,

bone marrow failure disorders

,

immunologic deficiency syndromes

,

intestinal neoplasms

,

basal cell carcinoma

,

large-cell lymphoma anaplastic

,

endometrioid carcinoma

,

,

severe acute respiratory syndrome-related coronavirus

,

primitive neuroectodermal tumors

,

neuroectodermal tumors

,

neuroendocrine tumors

,

severe acute respiratory syndrome

,

ductal carcinoma breast

,

,

cystic fibrosis

,

nontuberculous mycobacterium infections

,

pancreatic ductal carcinoma

,

cholangiocarcinoma

,

gallbladder neoplasms

,

myeloid leukemia accelerated phase

,

hypereosinophilic syndrome

,

residual neoplasm

,

appendiceal neoplasms

,

nasopharyngeal neoplasms

,

sickle cell anemia

,

beta-thalassemia

,

,

,

inborn errors metabolism

,

,

pulmonary hypertension

,

systemic scleroderma

,

,

interstitial lung diseases

,

diffuse scleroderma

,

lymphoproliferative disorders

,

,

sezary syndrome

,

mucinous adenocarcinoma

,

adenoid cystic carcinoma

,

mycosis fungoides

,

signet ring cell carcinoma

,

papillary adenocarcinoma

,

vulvar neoplasms

,

extramammary paget disease

,

keratoacanthoma

,

sweat gland neoplasms

,

basosquamous carcinoma

,

,

sebaceous adenocarcinoma

,

skin appendage carcinoma

,

glandular and epithelial neoplasms

,

thymus neoplasms

,

biliary tract neoplasms

,

second primary neoplasms

,

,

mucinous cystadenocarcinoma

,

serous cystadenocarcinoma

,

cystadenocarcinoma

,

,

,

malignant fibrous histiocytoma

,

,

viral pneumonia

,

adenocarcinoma in situ

,

,

cognitive dysfunction

,

,

,

,

unilateral breast neoplasms

,

hypersensitivity

,

kidney diseases

,

kidney transplantation

,

,

critical illness

,

immunosuppression therapy

,

,

trophoblastic neoplasms

,

,

,

,

,

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

erythroblastic leukemia acute

,

bile duct neoplasms

,

laryngeal neoplasms

,

,

,

chronic hepatitis c

,

ulcerative colitis

,

,

,

urologic neoplasms

,

,

,

,

,

soft tissue neoplasms

,

,

breast neoplasms

,

prostatic neoplasms

,

,

myelodysplastic syndromes

,

non-hodgkin lymphoma

,

,

,

,

pancreatic neoplasms

,

,

,

non-small-cell lung carcinoma

,

,

renal cell carcinoma

,

bcr-abl positive chronic myelogenous leukemia

,

,

pulmonary alveolar proteinosis

,

,

,

hepatocellular carcinoma

,

triple negative breast neoplasms

,

follicular lymphoma

,

,

squamous cell carcinoma

,

autoimmune diseases

,

communicable diseases

,

uveal neoplasms

,

rhabdomyosarcoma

,

,

large b-cell lymphoma diffuse

,

head and neck neoplasms

,

,

urinary bladder neoplasms

,

,

cutaneous malignant melanoma

,

,

,

,

squamous cell neoplasms

,

refractory anemia

,

ganglioneuroblastoma

,

,

transitional cell carcinoma

,

,

refractory anemia with excess of blasts

,

,

hematologic diseases

,

graft vs host disease

,

carcinoma in situ

,

radiation effects

,

coronavirus infections

,

,

alveolar rhabdomyosarcoma

,

embryonal rhabdomyosarcoma

,

cytomegalovirus retinitis

,

,

cutaneous leishmaniasis

,

,

multiple organ failure

,

neoplasms by histologic type

,

,

primitive neuroectodermal tumors peripheral

,

connective and soft tissue neoplasms

,

connective tissue neoplasms

,

bone tissue neoplasms

,

,

,

invasive fungal infections

,

adenoviridae infections

,

,

tongue neoplasms

,

,

,

,

,

multiple myeloma

,

plasma cell neoplasms

,

myeloid leukemia

,

myeloid leukemia acute

,

,

lymphoid leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

,

,

,

chronic hepatitis b

,

,

,

chronic hepatitis

,

,

,

,

respiratory insufficiency

,

wounds and injuries

,

,

spontaneous abortion

,

habitual abortion

,

,

,

,

intracytoplasmic sperm injections

,

liver cirrhosis

,

,

,

cytokine release syndrome

,

olfaction disorders

,

,

,

,

,

uterine neoplasms

,

female genital neoplasms

,

,

ovarian torsion

,

graft rejection

,

postoperative pain

,

,

non-alcoholic fatty liver disease

,

,

exocrine pancreatic insufficiency

,

periodontal diseases

,

,

,

Carboxymethylcellulose

,

postoperative complications

,

wounds and injuries

,

communicable diseases

,

,

musculoskeletal diseases

,

,

prosthesis-related infections

,

pathologic processes

,

brain neoplasms

,

,

head and neck neoplasms

,

pharyngeal neoplasms

,

squamous cell carcinoma

,

colorectal neoplasms

,

,

squamous cell neoplasms

,

breast neoplasms

,

,

,

non-small-cell lung carcinoma

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

colorectal neoplasms

,

pancreatic neoplasms

,

,

renal cell carcinoma

,

kidney neoplasms

,

,

non-small-cell lung carcinoma

,

,

urinary bladder neoplasms

,

,

,

transitional cell carcinoma

,

,

diffuse intrinsic pontine glioma

healthy volunteers/patients

,

pancreatic neoplasms

,

castration-resistant prostatic neoplasms

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

,

colorectal neoplasms

,

urinary bladder neoplasms

,

unknown primary neoplasms

,

pancreatic ductal carcinoma

,

,

hepatic insufficiency

,

renal insufficiency

,

myelodysplastic syndromes

,

,

,

non-small-cell lung carcinoma

,

,

triple negative breast neoplasms

,

multiple myeloma

,

,

ovarian neoplasms

,

non-hodgkin lymphoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

mantle-cell lymphoma

,

,

head and neck neoplasms

,

squamous cell neoplasms

,

plasma cell neoplasms

,

ovarian epithelial carcinoma

,

brain neoplasms

,

renal cell carcinoma

,

colonic neoplasms

,

,

,

medulloblastoma

,

,

,

rhabdomyosarcoma

,

diffuse intrinsic pontine glioma

,

small cell lung carcinoma

,

intraductal carcinoma noninfiltrating

,

b-cell lymphoma

,

prostatic neoplasms

,

second primary neoplasms

,

,

oligodendroglioma

,

transitional cell carcinoma

,

myeloid leukemia acute

,

myeloid leukemia

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

,

,

kidney diseases

,

urologic neoplasms

,

urogenital neoplasms

,

kidney neoplasms

,

urologic diseases

,

neoplasms by site

,

glandular and epithelial neoplasms

,

,

,

squamous cell carcinoma

,

squamous cell carcinoma of head and neck

,

male breast neoplasms

,

neoplasm metastasis

,

,

disease progression

,

breast neoplasms

,

,

,

parkinson disease

,

,

t-cell lymphoma cutaneous

,

,

diffuse intrinsic pontine glioma

,

,

,

acquired immunodeficiency syndrome

,

plasma cell leukemia

,

basal cell carcinoma

,

basal cell neoplasms

,

stem cell transplantation

,

hereditary breast and ovarian cancer syndrome

,

waldenstrom macroglobulinemia

,

paraproteinemias

,

,

precancerous conditions

,

smoldering multiple myeloma

,

,

carcinoid tumor

,

healthy volunteers/patients

,

respiratory syncytial virus infections

,

,

,

phenylketonurias

,

myasthenia gravis

,

muscle weakness

,

acinar cell carcinoma

,

conjunctival neoplasms

,

,

clear cell sarcoma

,

gastrointestinal stromal tumors

,

salivary gland neoplasms

,

testicular neoplasms

,

breast diseases

,

medullary carcinoma

,

mammary paget's disease

,

thrombocytopenia

,

paroxysmal hemoglobinuria

,

,

,

large-cell lymphoma anaplastic

,

,

parkinsonian disorders

,

pharmacokinetics

,

lymphatic metastasis

,

,

ovarian neoplasms

,

,

colorectal neoplasms

,

,

ovarian epithelial carcinoma

,

non-small-cell lung carcinoma

,

b-cell chronic lymphocytic leukemia

,

myeloproliferative disorders

,

fallopian tube neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

kidney neoplasms

,

neoplasm metastasis

,

hodgkin disease

,

stomach neoplasms

,

b-cell lymphoma

,

brain neoplasms

,

liver neoplasms

,

myelodysplastic-myeloproliferative diseases

,

,

,

,

male breast neoplasms

,

germ cell and embryonal neoplasms

,

colonic neoplasms

,

malignant mesothelioma

,

,

hematologic neoplasms

,

follicular lymphoma

,

squamous cell carcinoma

,

oligodendroglioma

,

respiratory distress syndrome

,

medulloblastoma

,

,

peritoneal neoplasms

,

,

squamous cell carcinoma of head and neck

,

esophageal neoplasms

,

hepatocellular carcinoma

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

myeloid leukemia chronic-phase

,

small cell lung carcinoma

,

rectal neoplasms

,

mantle-cell lymphoma

,

,

castration-resistant prostatic neoplasms

,

alzheimer disease

,

endometrial neoplasms

,

drug-related side effects and adverse reactions

,

peripheral arterial disease

,

peripheral vascular diseases

,

uterine cervical neoplasms

,

acute lung injury

,

newborn respiratory distress syndrome

,

ductal carcinoma

,

intraductal carcinoma noninfiltrating

,

respiratory aspiration

,

alveolar soft part sarcoma

,

inflammatory breast neoplasms

,

aplastic anemia

,

t-cell lymphoma peripheral

,

,

graft vs host disease

,

rheumatoid arthritis

,

intestinal neoplasms

,

endometrioid carcinoma

,

merkel cell carcinoma

,

squamous cell neoplasms

,

primitive neuroectodermal tumors

,

neuroectodermal tumors

,

neuroendocrine tumors

,

severe acute respiratory syndrome

,

carcinoma in situ

,

ductal carcinoma breast

,

,

cystic fibrosis

,

nontuberculous mycobacterium infections

,

mycobacterium infections

,

pancreatic ductal carcinoma

,

myelomonocytic leukemia acute

,

transitional cell carcinoma

,

cholangiocarcinoma

,

gallbladder neoplasms

,

myeloid leukemia accelerated phase

,

residual neoplasm

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

gastrointestinal neoplasms

,

immunologic deficiency syndromes

,

t-cell lymphoma

,

immunoglobulin light-chain amyloidosis

,

,

lymphoproliferative disorders

,

,

glandular and epithelial neoplasms

,

thymus neoplasms

,

biliary tract neoplasms

,

,

mucinous cystadenocarcinoma

,

serous cystadenocarcinoma

,

cystadenocarcinoma

,

,

adenocarcinoma in situ

,

,

cognitive dysfunction

,

,

severe acute respiratory syndrome-related coronavirus

,

,

unilateral breast neoplasms

,

hypersensitivity

,

kidney diseases

,

kidney transplantation

,

critical illness

,

immunosuppression therapy

,

,

trophoblastic neoplasms

,

,

,

invasive hydatidiform mole

,

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

erythroblastic leukemia acute

,

bile duct neoplasms

,

laryngeal neoplasms

,

burkitt lymphoma

,

ulcerative colitis

,

,

,

urologic neoplasms

,

,

,

,

,

soft tissue neoplasms

,

breast neoplasms

,

prostatic neoplasms

,

multiple myeloma

,

myeloid leukemia

,

plasma cell neoplasms

,

myelodysplastic syndromes

,

,

non-hodgkin lymphoma

,

,

,

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

pancreatic neoplasms

,

pulmonary alveolar proteinosis

,

,

renal cell carcinoma

,

,

uveal neoplasms

,

,

autoimmune diseases

,

communicable diseases

,

,

triple negative breast neoplasms

,

rhabdomyosarcoma

,

,

,

cutaneous malignant melanoma

,

large b-cell lymphoma diffuse

,

refractory anemia

,

head and neck neoplasms

,

,

ganglioneuroblastoma

,

,

refractory anemia with excess of blasts

,

hematologic diseases

,

,

urinary bladder neoplasms

,

radiation effects

,

,

alveolar rhabdomyosarcoma

,

embryonal rhabdomyosarcoma

,

cytomegalovirus retinitis

,

,

cutaneous leishmaniasis

,

,

coronavirus infections

,

,

,

invasive fungal infections

,

,

,

tongue neoplasms

,

,

,

,

,

myeloid leukemia acute

,

lymphoid leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

,

,

chronic hepatitis b

,

,

,

chronic hepatitis

,

,

,

,

wounds and injuries

,

,

respiratory insufficiency

,

bone marrow failure disorders

,

,

liver cirrhosis

,

graft rejection

,

,

periodontal diseases

,

,

Histone-arginine methyltransferase carm1

pharmacokinetics

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

positron-emission tomography

,

,

alzheimer disease

,

diagnostic imaging

,

medical sociology

,

,

,

drug interactions

,

electrocardiography

,

therapeutic equivalency

,

pharmacological phenomena

,

,

,

stomach neoplasms

,

hypophosphatemia

,

hematologic neoplasms

,

respiratory aspiration

,

cystic fibrosis

,

pseudomonas infections

,

biological availability

,

castration-resistant prostatic neoplasms

,

,

non-small-cell lung carcinoma

,

,

breast neoplasms

,

postcoital contraception

,

ovulation inhibition

,

atrial fibrillation

,

,

parkinson disease

,

small cell lung carcinoma

,

ovarian neoplasms

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

,

cardiomyopathies

,

,

,

,

overactive urinary bladder

,

hormonal contraception

,

unplanned pregnancy

,

b-cell lymphoma

,

,

skin abnormalities

,

myocardial infarction

,

,

,

acquired immunodeficiency syndrome

,

magnetic resonance angiography

,

,

left ventricular dysfunction

,

ventricular dysfunction

,

interstitial lung diseases

,

ovarian epithelial carcinoma

,

thyroid neoplasms

,

thyroid diseases

,

pancreatic neoplasms

,

,

,

,

,

prostatic hyperplasia

,

,

angina pectoris

,

,

ischemic stroke

,

,

cerebral infarction

,

urologic neoplasms

,

head and neck neoplasms

,

thromboembolism

,

venous thromboembolism

,

pulmonary hypertension

,

,

hyperphosphatemia

,

,

prostatic neoplasms

,

,

venous thrombosis

,

non-hodgkin lymphoma

,

,

chronic renal insufficiency

,

kidney diseases

,

surgical blood loss

,

,

,

vascular diseases

,

peripheral arterial disease

,

peripheral vascular diseases

,

postoperative hemorrhage

,

pulmonary embolism

,

,

cardiovascular diseases

,

,

,

spinal cord injuries

,

pathologic constriction

,

renal artery obstruction

,

,

bacterial infections

,

esophageal neoplasms

,

,

,

intraabdominal infections

,

,

chronic progressive multiple sclerosis

,

blood coagulation disorders

,

hemostatic disorders

,

hormone replacement therapy

,

hyperlipidemias

,

hyperlipoproteinemias

,

choroidal neovascularization

,

,

degenerative myopia

,

pathologic neovascularization

,

,

aspiration pneumonia

,

,

,

pelvic infection

,

pelvic inflammatory disease

,

,

metabolic bone diseases

,

,

premenstrual dysphoric disorder

,

diabetic nephropathies

,

,

follicular lymphoma

,

wounds and injuries

,

brain neoplasms

,

congenital abnormalities

,

cardiovascular abnormalities

,

,

memory disorders

,

carotid stenosis

,

pulmonary arterial hypertension

,

,

,

depressive disorder

,

hypersensitivity

,

aortic valve stenosis

,

heart valve diseases

,

ventricular outflow obstruction

,

abdominal abscess

,

erectile dysfunction

,

,

,

,

,

,

,

healthy volunteers/patients

,

renal cell carcinoma

,

communicable diseases

,

multiple sclerosis

,

,

,

,

essential hypertension

,

atopic dermatitis

,

,

liver neoplasms

,

,

relapsing-remitting multiple sclerosis

,

,

hepatocellular carcinoma

,

urinary tract infections

,

diabetes mellitus

,

coronary artery disease

,

,

type 2 diabetes mellitus

,

colorectal neoplasms

,

,

,

,

physiological sexual dysfunction

,

magnetic resonance imaging

,

neoplasm metastasis

,

coronary disease

,

acute coronary syndrome

,

myocardial ischemia

,

,

tension-type headache

,

,

,

renal insufficiency

,

chronic bronchitis

,

,

,

,

,

respiratory tract infections

,

,

peripheral nervous system diseases

,

ischemic optic neuropathy

,

optic nerve diseases

,

,

,

macular degeneration

,

energy metabolism

,

,

maxillary sinusitis

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

medicated intrauterine devices

,

,

gene expression

,

cell proliferation

,

,

central nervous system neoplasms

,

photoallergic dermatitis

,

phototoxic dermatitis

,

four-dimensional computed tomography

chronic kidney failure

,

bullous pemphigoid

,

hemolytic anemia autoimmune

,

hemolytic anemia

,

breast neoplasms

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