Scilex Pharmaceuticals - PharmaKB

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Company ReportsScilex Pharmaceuticals

Scilex Pharmaceuticals

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Gloperba	Colchicine	2019-01-30	2028-2037	Gonorrhea , Biliary liver cirrhosis , Amyloidosis , Neurosyphilis , Familial mediterranean fever , Gout
Ztlido	Lidocaine	2018-02-28	2026-2035	Pain , Ventricular tachycardia , Cardiac arrhythmias , Burns , Esophageal diseases , Ventricular fibrillation , Physiological sexual dysfunction , Ventricular premature complexes , Mouth diseases , Paroxysmal tachycardia , Premature ejaculation , Sepsis , Urinary tract infections , Otitis media , Bacterial infections , Gonorrhea , Pseudomonas infections , Bacterial skin diseases , Escherichia coli infections , Pelvic infection , Soft tissue infections , Clostridium infections , Streptococcal infections , Lyme disease , Bacterial pneumonia , Staphylococcal infections , Proctocolitis , Peritonitis , Bacterial meningitis , Salmonella infections , Proteus infections , Infectious bone diseases , Acinetobacter infections , Klebsiella infections , Enteritis , Epididymitis , Chancroid , Bacteroidaceae infections , Serratia infections , Septic shock , Hypotension , Anaphylaxis , Bradycardia , Heart arrest , Open-angle glaucoma , Heart block , Airway obstruction , Bronchial spasm , Myocardial infarction , Migraine disorders , Pulmonary embolism , Postoperative complications , Thromboembolism , Cerebral infarction , Coronary thrombosis , Unstable angina , Orthostatic hypotension , Cluster headache , Postpartum hemorrhage , Xerostomia , Thrombophlebitis , Leukemia , Ulcerative colitis , Ankylosing spondylitis , Vomiting , Nausea , Sarcoidosis , Thrombocytopenic purpura idiopathic , Pulmonary tuberculosis , Mycosis fungoides , Systemic lupus erythematosus , Rheumatic diseases , Bursitis , Keratitis , Allergic rhinitis perennial , Thyroiditis , Iritis , Hypercalcemia , Brain edema , Pemphigus , Addison disease , Collagen diseases , Dermatitis herpetiformis , Acne vulgaris , Chlamydia infections , Syphilis , Borrelia infections , Gram-positive bacterial infections , Rickettsia infections , Mycoplasma infections , Protozoan infections , Psittacosis , Wounds and injuries , Gastrointestinal diseases , Pneumonia , Skin diseases , Bacterial eye infections , Urinary bladder diseases , Hepatic encephalopathy , Bacteremia , Empyema , Otitis externa , Haemophilus infections , Pseudomembranous enterocolitis , Postoperative pain
Elyxyb	Celecoxib	2020-05-05	2029-2038	Ankylosing spondylitis , Rheumatoid arthritis , Osteoarthritis , Adenomatous polyposis coli , Dysmenorrhea , Hypertension , Coronary artery disease , Variant angina pectoris , Pain

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

knee osteoarthritis

tissue adhesions

,

healthy volunteers/patients

Bos taurus adrenal cortex corticosteroids

tissue adhesions

,

healthy volunteers/patients

healthy volunteers/patients

,

hepatic insufficiency

,

,

diabetes mellitus

,

autism spectrum disorder

,

marijuana abuse

,

sturge-weber syndrome

,

type 2 diabetes mellitus

,

,

brain neoplasms

,

,

cognitive dysfunction

,

drug resistant epilepsy

,

,

mental disorders

,

,

,

neuromyelitis optica

,

autistic disorder

,

wounds and injuries

,

,

,

,

peripheral nervous system diseases

,

infantile spasms

,

,

anxiety disorders

,

,

,

psychotic disorders

,

spinal cord injuries

,

,

post-traumatic stress disorders

,

traumatic stress disorders

,

palliative care

,

postoperative nausea and vomiting

,

postoperative pain

,

,

overactive urinary bladder

,

diabetic neuropathies

,

multiple sclerosis

,

,

,

muscle spasticity

,

,

myoclonic epilepsies

,

lennox gastaut syndrome

,

tuberous sclerosis

,

liver cirrhosis

,

,

central nervous system diseases

,

,

pregnancy complications

,

ovarian neoplasms

,

subarachnoid hemorrhage

,

uterine cervical neoplasms

,

,

intracranial vasospasm

,

,

epidural neoplasms

,

aortic coarctation

,

,

coronary occlusion

,

trigeminal nerve injuries

,

trigeminal neuralgia

,

glossopharyngeal nerve diseases

,

,

,

substance-related disorders

,

parkinson disease

,

spinal cord compression

,

intracranial hypotension

,

,

,

,

chronic pancreatitis

,

,

,

,

,

non-small-cell lung carcinoma

,

femoral fractures

,

,

gastrointestinal neoplasms

,

injection site reaction

,

postoperative cognitive complications

,

cerebrospinal fluid leak

,

natural childbirth

,

primary dysautonomias

,

vascular diseases

,

peripheral arterial disease

,

,

biliary tract neoplasms

,

acupuncture analgesia

,

head and neck neoplasms

,

thyroid neoplasms

,

digestive system neoplasms

,

,

unknown primary neoplasms

,

major depressive disorder

,

diverticular diseases

,

peripheral vascular diseases

,

,

pulmonary emphysema

,

anterior cruciate ligament injuries

,

duodenal neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

interdigitating dendritic cell sarcoma

,

spinal cord injuries

,

,

,

,

liver neoplasms

,

,

obstetrical anesthesia

,

,

healthy volunteers/patients

,

video-assisted thoracic surgery

,

,

intractable pain

,

,

breast neoplasms

,

,

inflammatory bowel diseases

,

,

,

hepatocellular carcinoma

,

,

,

acute kidney injury

,

,

spinal fractures

,

intraoperative complications

,

endometrial neoplasms

,

,

,

pancreatic diseases

,

,

,

umbilical hernia

,

pelvic floor disorders

,

procedural pain

,

,

,

,

peritoneal neoplasms

,

,

digestive system diseases

,

intrahepatic cholestasis

,

,

congenital cystic adenomatoid malformation of lung

,

,

von willebrand diseases

,

brachial plexus block

,

respiratory paralysis

,

osteoid osteoma

,

,

elective surgical procedures

,

,

perioperative care

,

fetal growth retardation

,

diaphragmatic hernias congenital

,

diaphragmatic hernia

,

postoperative pain

,

,

,

,

epidural anesthesia

,

,

epidural analgesia

,

,

,

,

,

wounds and injuries

,

intervertebral disc displacement

,

spinal stenosis

,

,

,

cesarean section

,

post-dural puncture headache

,

,

,

,

,

,

,

pathologic constriction

,

,

,

failed back surgery syndrome

,

intervertebral disc degeneration

,

aortic dissection

,

replacement arthroplasty knee

,

,

,

,

pancreatic neoplasms

,

postpartum depression

,

obstetric labor complications

,

patient satisfaction

,

postoperative complications

,

urinary retention

,

anesthesia and analgesia

,

local anesthesia

,

conduction anesthesia

,

,

colorectal neoplasms

,

,

thoracic surgical procedures

,

,

abdominal neoplasms

,

colonic neoplasms

,

,

,

stomach neoplasms

,

,

obstetrical analgesia

,

general anesthesia

,

,

spinal anesthesia

,

,

obstetric labor

,

emergence delirium

,

pain management

,

depressive disorder

,

prostatic neoplasms

,

,

anxiety disorders

,

knee osteoarthritis

,

breakthrough pain

,

,

,

female genital diseases

,

,

,

,

caudal anesthesia

,

drug-related side effects and adverse reactions

,

,

,

,

complex regional pain syndromes

,

postoperative period

,

respiratory insufficiency

,

,

,

esophageal neoplasms

,

,

,

,

reflex sympathetic dystrophy

,

somatoform disorders

,

,

,

,

patient-controlled analgesia

,

renal cell carcinoma

,

kidney neoplasms

,

female genital neoplasms

,

postherpetic neuralgia

,

postpartum hemorrhage

,

,

cognitive dysfunction

,

myofascial pain syndromes

,

hip osteoarthritis

,

pain measurement

,

morphine dependence

,

psychomotor agitation

,

premature rupture fetal membranes

,

,

enhanced recovery after surgery

,

pleural diseases

,

,

anesthesia recovery period

,

,

cervical ripening

,

pulmonary atelectasis

,

,

neurosurgical procedures

,

,

,

premature birth

,

coronary artery bypass

,

,

replacement arthroplasty hip

,

circulating neoplastic cells

,

pleural effusion

,

hip dislocation

,

lymphadenopathy

,

,

,

,

hemiarthroplasty

,

angina pectoris

,

,

abdominal hernia

,

,

pancreaticoduodenectomy

,

,

,

,

cardiac arrhythmias

,

delayed emergence from anesthesia

,

closed fractures

,

immunosuppression therapy

,

operative surgical procedures

,

residual neoplasm

,

systemic inflammatory response syndrome

,

postoperative hemorrhage

,

blood coagulation disorders

,

hemostatic disorders

,

spondylarthritis

,

,

axial spondyloarthritis

,

,

digestive system surgical procedures

,

post-head injury coma

,

,

electroencephalography

,

mouth neoplasms

,

,

malignant pleural effusion

,

pleural empyema

,

,

pericardial effusion

,

pleural neoplasms

,

,

,

gynecologic surgical procedures

,

opioid-related disorders

,

epidural hematoma spinal

,

traumatic brain injuries

,

,

,

inguinal hernia

,

ultrasonography

,

epidural hematoma cranial

,

,

,

,

nervous system diseases

,

thoracic neoplasms

,

thoracic injuries

,

rectal neoplasms

,

,

headache disorders

,

muscle spasticity

,

neoplasm metastasis

,

urinary tract infections

,

,

,

obstetric delivery

,

urinary bladder neoplasms

,

sleep wake disorders

,

,

spinal cord stimulation

,

spinal diseases

,

spinal cord diseases

,

epidural injections

,

,

epidural abscess

,

percutaneous nephrolithotomy

,

,

laparoscopic cholecystectomy

,

,

,

spondylolisthesis

,

restless legs syndrome

,

,

intermittent claudication

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

,

atrial fibrillation

,

personal satisfaction

,

,

,

cholecystolithiasis

,

postoperative nausea and vomiting

,

,

,

male circumcision

,

congenital abnormalities

,

neurologic gait disorders

,

,

cardiovascular diseases

,

craniocerebral trauma

,

closed head injuries

,

orthostatic hypotension

,

life change events

,

spinal cord neoplasms

,

,

communicable diseases

,

neuroimmunomodulation

,

pregnancy complications

,

surgical blood loss

,

musculoskeletal diseases

,

respiratory aspiration

,

,

bariatric surgery

,

,

congenital pain insensitivity

,

compression fractures

,

,

,

insulin resistance

,

neurologic manifestations

,

mental disorders

,

,

prostatic hyperplasia

,

coronary artery disease

,

colonic diverticulosis

,

whiplash injuries

,

,

decompressive craniectomy

,

,

venous insufficiency

,

,

,

,

neurogenic urinary bladder

,

autonomic dysreflexia

,

,

obstructive sleep apnea

,

,

joint dislocations

,

pneumoperitoneum

,

,

traumatic amputation

,

central nervous system diseases

,

multiple trauma

,

penetrating head injuries

,

neurogenic bowel

,

shy-drager syndrome

,

thoracic diseases

,

cauda equina syndrome

,

minimally invasive surgical procedures

,

,

,

cerebral infarction

,

,

urologic diseases

,

nephrolithiasis

,

,

,

magnetic resonance imaging

,

,

spinal neoplasms

,

neurodevelopmental disorders

,

,

myocardial ischemia

,

,

aortic aneurysm

,

multiple sclerosis

,

,

tracheal stenosis

,

spinal muscular atrophy

,

spinal muscular atrophies of childhood

,

,

intraoperative awareness

,

multiple system atrophy

,

parkinsonian disorders

,

,

,

asphyxia neonatorum

,

uterine contraction

,

psychological well-being

,

,

,

,

,

artificial respiration

,

colonic pseudo-obstruction

,

hepatic insufficiency

,

ultrasonic therapy

,

multiple fractures

,

respiration disorders

,

uterine cervical incompetence

,

solitary kidney

,

muscle weakness

,

,

neuromuscular blockade

,

rectal diseases

,

,

,

,

,

newborn infant diseases

,

cutaneous fistula

,

,

renal insufficiency

,

end stage liver disease

,

reperfusion injury

,

osteoporotic fractures

,

breech presentation

,

,

brachial plexus neuritis

,

oxidative stress

,

,

signs and symptoms

,

signs and symptoms pathological conditions

,

pancreatic fistula

,

,

acute hemorrhagic pancreatitis

,

liver transplantation

,

,

pregnancy outcome

,

,

acupuncture therapy

,

intestinal diseases

,

electroacupuncture

,

,

sleep initiation and maintenance disorders

,

sleep deprivation

,

circadian rhythm sleep disorders

,

,

first labor stage

,

horner syndrome

,

transurethral resection of prostate

,

,

fallopian tube neoplasms

,

pulmonary embolism

,

,

sphenopalatine ganglion block

,

cholangiocarcinoma

,

,

biliary tract diseases

,

choledocholithiasis

,

pelvic organ prolapse

,

urinary incontinence

,

,

child development

,

,

pulmonary surgical procedures

,

transplantation

,

maternal-fetal relations

,

enzyme induction

,

,

,

,

free tissue flaps

,

,

,

fecal incontinence

,

intracranial pressure

,

disease progression

,

isolated systolic hypertension

,

congenital hip dislocation

,

developmental dysplasia of the hip

,

,

,

arnold-chiari malformation

,

,

pseudotumor cerebri

,

central nervous system infections

,

,

breast diseases

,

implanted electrodes

,

,

,

intracranial hypertension

,

progressive supranuclear palsy

,

,

mitochondrial genome

,

nervous system trauma

,

peripheral nervous system diseases

,

diabetic neuropathies

,

,

,

stress urinary incontinence

,

sleep apnea syndromes

,

,

,

,

,

,

cardiomyopathies

,

dilated cardiomyopathy

,

diagnostic imaging

,

urinary catheters

,

attitudes health knowledge practice

,

,

respiratory physiological phenomena

,

local neoplasm recurrence

,

,

,

fetofetal transfusion

,

fetal therapies

,

,

water-electrolyte balance

,

second labor stage

,

intestinal obstruction

,

,

brain concussion

,

,

attention deficit disorder with hyperactivity

,

critical illness

,

lens subluxation

,

catheter-related infections

,

,

,

tubal sterilization

,

autonomic nervous system diseases

,

surgical wound infection

,

carotid stenosis

,

,

,

treatment-resistant depressive disorder

,

,

ureteral calculi

,

ureterolithiasis

,

femoracetabular impingement

,

intratracheal intubation

,

,

overactive urinary bladder

,

palliative care

,

hemodynamic monitoring

,

,

autoimmune diseases

,

demyelinating diseases

,

,

metabolic syndrome

,

central nervous system sensitization

,

anastomotic leak

,

nociceptive pain

,

urologic neoplasms

,

male urogenital diseases

,

internal hernia

,

urogenital diseases

,

uterine diseases

,

,

,

interstitial lung diseases

,

,

breathing exercises

,

,

renal nutcracker syndrome

,

catheter obstruction

,

,

tibial fractures

,

,

hereditary spastic paraplegia

,

variant angina pectoris

,

radical mastectomy

,

,

abdominal aortic aneurysm

,

,

,

endotracheal anesthesia

,

muscle rigidity

,

,

,

motor neuron disease

,

open abdomen techniques

,

respiratory distress syndrome

,

,

surgical amputation

,

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

,

,

cold temperature

,

,

sprains and strains

,

echocardiography

,

,

intracranial hemorrhages

,

traumatic brain hemorrhage

,

epidural blood patch

,

adrenoleukodystrophy

,

intraocular injections

,

doppler ultrasonography

,

pure autonomic failure

,

risk reduction behavior

,

propionibacterium acnes

,

chronic disease

,

,

psychological burnout

,

,

pathologic processes

,

,

cross infection

,

congenital heart defects

,

,

,

war-related injuries

,

spinal injections

,

urologic surgical procedures

,

chronic kidney failure

,

kidney diseases

,

kidney transplantation

,

multiple organ failure

,

ischemic stroke

,

brain neoplasms

,

cerebral hemorrhage

,

subdural hematoma

Histone-arginine methyltransferase carm1

healthy volunteers/patients

,

,

pharmacokinetics

,

,

,

ocular hypertension

,

open-angle glaucoma

,

multiple myeloma

,

plasma cell neoplasms

,

erectile dysfunction

,

gastrointestinal neoplasms

,

,

renal cell carcinoma

,

,

breast neoplasms

,

,

triple negative breast neoplasms

,

,

pancreatic neoplasms

,

prostatic neoplasms

,

squamous cell carcinoma of head and neck

,

,

,

squamous cell carcinoma

,

,

castration-resistant prostatic neoplasms

,

non-hodgkin lymphoma

,

follicular lymphoma

,

colorectal neoplasms

,

stomach neoplasms

,

,

biliary tract neoplasms

,

,

uterine cervical neoplasms

,

endometrial neoplasms

,

large b-cell lymphoma diffuse

,

transitional cell carcinoma

,

chronic hepatitis

,

,

gastrointestinal diseases

,

,

rna virus infections

,

digestive system diseases

,

viral hepatitis human

,

flaviviridae infections

,

general anesthesia

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

obstructive sleep apnea

,

sleep apnea syndromes

,

,

,

disorders of excessive somnolence

,

,

papillomavirus infections

,

vaginal neoplasms

,

vulvar neoplasms

,

condylomata acuminata

,

hodgkin disease

,

migraine disorders

,

atherosclerosis

,

esophageal neoplasms

,

uterine neoplasms

,

,

mullerian mixed tumor

,

,

esophageal squamous cell carcinoma

,

b-cell lymphoma

,

neuroendocrine tumors

,

intestinal neoplasms

,

head and neck neoplasms

,

x-linked bulbo-spinal atrophy

,

prostatic hyperplasia

,

,

muscular atrophy

,

,

,

urologic neoplasms

,

hepatocellular carcinoma

,

urinary bladder neoplasms

,

liver neoplasms

,

microsatellite instability

,

hidradenitis suppurativa

,

merkel cell carcinoma

,

non-small-cell lung carcinoma

,

chronic hepatitis c

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

,

small cell lung carcinoma

,

,

,

neoplasm metastasis

,

urinary tract infections

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

,

,

polycystic kidney diseases

,

,

spondylarthritis

,

,

axial spondyloarthritis

,

,

postherpetic neuralgia

,

,

,

,

,

ovarian neoplasms

,

,

acquired immunodeficiency syndrome

,

,

communicable diseases

,

,

,

,

,

,

kidney diseases

,

rheumatoid arthritis

,

ovarian epithelial carcinoma

,

hepatitis a virus

,

immunosuppression therapy

,

,

chronic renal insufficiency

,

chronic disease

,

drug-related side effects and adverse reactions

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