Scilex Pharmaceuticals - PharmaKB

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Company ReportsScilex Pharmaceuticals

Scilex Pharmaceuticals

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Gloperba	Colchicine	2019-01-30	2028-2037	Gonorrhea , Biliary liver cirrhosis , Amyloidosis , Neurosyphilis , Familial mediterranean fever , Gout
Ztlido	Lidocaine	2018-02-28	2026-2035	Pain , Ventricular tachycardia , Cardiac arrhythmias , Burns , Esophageal diseases , Ventricular fibrillation , Physiological sexual dysfunction , Ventricular premature complexes , Mouth diseases , Paroxysmal tachycardia , Premature ejaculation , Sepsis , Urinary tract infections , Otitis media , Bacterial infections , Gonorrhea , Pseudomonas infections , Bacterial skin diseases , Escherichia coli infections , Pelvic infection , Soft tissue infections , Clostridium infections , Streptococcal infections , Lyme disease , Bacterial pneumonia , Staphylococcal infections , Proctocolitis , Peritonitis , Bacterial meningitis , Salmonella infections , Proteus infections , Infectious bone diseases , Acinetobacter infections , Klebsiella infections , Enteritis , Epididymitis , Chancroid , Bacteroidaceae infections , Serratia infections , Septic shock , Hypotension , Anaphylaxis , Bradycardia , Heart arrest , Open-angle glaucoma , Heart block , Airway obstruction , Bronchial spasm , Myocardial infarction , Migraine disorders , Pulmonary embolism , Postoperative complications , Thromboembolism , Cerebral infarction , Coronary thrombosis , Unstable angina , Orthostatic hypotension , Cluster headache , Postpartum hemorrhage , Xerostomia , Thrombophlebitis , Leukemia , Ulcerative colitis , Ankylosing spondylitis , Vomiting , Nausea , Sarcoidosis , Thrombocytopenic purpura idiopathic , Pulmonary tuberculosis , Mycosis fungoides , Systemic lupus erythematosus , Rheumatic diseases , Bursitis , Keratitis , Allergic rhinitis perennial , Thyroiditis , Iritis , Hypercalcemia , Brain edema , Pemphigus , Addison disease , Collagen diseases , Dermatitis herpetiformis , Acne vulgaris , Chlamydia infections , Syphilis , Borrelia infections , Gram-positive bacterial infections , Rickettsia infections , Mycoplasma infections , Protozoan infections , Psittacosis , Wounds and injuries , Gastrointestinal diseases , Pneumonia , Skin diseases , Bacterial eye infections , Urinary bladder diseases , Hepatic encephalopathy , Bacteremia , Empyema , Otitis externa , Haemophilus infections , Pseudomembranous enterocolitis , Postoperative pain
Elyxyb	Celecoxib	2020-05-05	2029-2038	Ankylosing spondylitis , Rheumatoid arthritis , Osteoarthritis , Adenomatous polyposis coli , Dysmenorrhea , Hypertension , Coronary artery disease , Variant angina pectoris , Pain

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

renal insufficiency

,

thromboembolism

,

respiratory tract infections

,

,

healthy volunteers/patients

,

healthy volunteers/patients

,

,

,

,

ventilator-associated pneumonia

,

,

,

,

alcohol drinking

,

vascular stiffness

,

,

,

tissue adhesions

,

,

,

human influenza

,

,

peripheral nervous system diseases

,

chronic obstructive pulmonary disease

,

,

,

irritable bowel syndrome

,

,

,

breast neoplasms

,

obstructive lung diseases

,

,

colonic diseases

,

diabetic neuropathies

,

inflammatory bowel diseases

,

intestinal diseases

,

nervous system diseases

,

deglutition disorders

,

spinocerebellar degenerations

,

spinocerebellar ataxias

,

machado-joseph disease

,

,

,

ischemic stroke

,

,

,

cerebral infarction

,

tobacco use disorder

,

,

tobacco smoking

,

cigarette smoking

,

,

,

smoking cessation

,

,

,

tobacco use cessation

,

musculoskeletal pain

,

colonic neoplasms

,

stomach neoplasms

,

,

gastrointestinal endoscopy

,

,

pharyngeal diseases

,

,

esophageal neoplasms

,

,

,

prehypertension

,

aphthous stomatitis

,

,

,

,

,

opioid-related disorders

,

,

knee osteoarthritis

,

,

,

diabetes mellitus

,

,

,

,

cesarean section

,

,

respiratory tract infections

,

,

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

actinic keratosis

,

,

,

,

,

,

,

,

immunologic cytotoxicity

,

,

,

,

,

,

migraine disorders

,

,

,

,

substance-related disorders

,

cognitive dysfunction

,

,

,

,

,

,

,

,

uterine cervical dysplasia

,

carpal tunnel syndrome

,

positron-emission tomography

,

,

child development

,

obstructive sleep apnea

,

sleep apnea syndromes

,

perioperative nursing

,

nasal obstruction

,

,

,

,

environmental biomarkers

,

,

health behavior

,

oropharyngeal neoplasms

,

percutaneous coronary intervention

,

myocardial infarction

,

coronary artery bypass

,

,

type 2 diabetes mellitus

,

addictive behavior

,

,

tendon injuries

,

,

,

atopic dermatitis

,

,

,

,

,

neurogenic inflammation

,

uterine cervical neoplasms

,

musculoskeletal diseases

,

,

respiratory tract diseases

,

,

,

smoking reduction

,

acupuncture therapy

,

post-traumatic stress disorders

,

traumatic stress disorders

,

postoperative nausea and vomiting

,

hospitalization

,

,

myofascial pain syndromes

,

,

wounds and injuries

,

postoperative pain

,

,

,

gallbladder diseases

,

,

neurocognitive disorders

,

premature birth

,

premature ejaculation

,

,

opiate substitution treatment

,

minimally invasive surgical procedures

,

,

olfaction disorders

muscular atrophy

,

spinal muscular atrophy

,

,

spinal muscular atrophies of childhood

pharmacokinetics

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

positron-emission tomography

,

,

alzheimer disease

,

diagnostic imaging

,

medical sociology

,

,

,

drug interactions

,

electrocardiography

,

therapeutic equivalency

,

pharmacological phenomena

,

,

,

stomach neoplasms

,

hypophosphatemia

,

hematologic neoplasms

,

respiratory aspiration

,

cystic fibrosis

,

pseudomonas infections

,

biological availability

,

castration-resistant prostatic neoplasms

,

,

non-small-cell lung carcinoma

,

,

breast neoplasms

,

postcoital contraception

,

ovulation inhibition

,

atrial fibrillation

,

,

parkinson disease

,

small cell lung carcinoma

,

ovarian neoplasms

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

,

cardiomyopathies

,

,

,

,

overactive urinary bladder

,

hormonal contraception

,

unplanned pregnancy

,

b-cell lymphoma

,

,

skin abnormalities

,

myocardial infarction

,

,

,

acquired immunodeficiency syndrome

,

magnetic resonance angiography

,

,

left ventricular dysfunction

,

ventricular dysfunction

,

interstitial lung diseases

,

ovarian epithelial carcinoma

,

thyroid neoplasms

,

thyroid diseases

,

pancreatic neoplasms

,

,

,

,

,

prostatic hyperplasia

,

,

angina pectoris

,

,

ischemic stroke

,

,

cerebral infarction

,

urologic neoplasms

,

head and neck neoplasms

,

thromboembolism

,

venous thromboembolism

,

pulmonary hypertension

,

,

hyperphosphatemia

,

,

prostatic neoplasms

,

,

venous thrombosis

,

non-hodgkin lymphoma

,

,

chronic renal insufficiency

,

kidney diseases

,

surgical blood loss

,

,

,

vascular diseases

,

peripheral arterial disease

,

peripheral vascular diseases

,

postoperative hemorrhage

,

pulmonary embolism

,

,

cardiovascular diseases

,

,

,

spinal cord injuries

,

pathologic constriction

,

renal artery obstruction

,

,

bacterial infections

,

esophageal neoplasms

,

,

,

intraabdominal infections

,

,

chronic progressive multiple sclerosis

,

blood coagulation disorders

,

hemostatic disorders

,

hormone replacement therapy

,

hyperlipidemias

,

hyperlipoproteinemias

,

choroidal neovascularization

,

,

degenerative myopia

,

pathologic neovascularization

,

,

aspiration pneumonia

,

,

,

pelvic infection

,

pelvic inflammatory disease

,

,

metabolic bone diseases

,

,

premenstrual dysphoric disorder

,

diabetic nephropathies

,

,

follicular lymphoma

,

wounds and injuries

,

brain neoplasms

,

congenital abnormalities

,

cardiovascular abnormalities

,

,

memory disorders

,

carotid stenosis

,

pulmonary arterial hypertension

,

,

,

depressive disorder

,

hypersensitivity

,

aortic valve stenosis

,

heart valve diseases

,

ventricular outflow obstruction

,

abdominal abscess

,

erectile dysfunction

,

,

,

,

,

,

,

healthy volunteers/patients

,

renal cell carcinoma

,

communicable diseases

,

multiple sclerosis

,

,

,

,

essential hypertension

,

atopic dermatitis

,

,

liver neoplasms

,

,

relapsing-remitting multiple sclerosis

,

,

hepatocellular carcinoma

,

urinary tract infections

,

diabetes mellitus

,

coronary artery disease

,

,

type 2 diabetes mellitus

,

colorectal neoplasms

,

,

,

,

physiological sexual dysfunction

,

magnetic resonance imaging

,

neoplasm metastasis

,

coronary disease

,

acute coronary syndrome

,

myocardial ischemia

,

,

tension-type headache

,

,

,

renal insufficiency

,

chronic bronchitis

,

,

,

,

,

respiratory tract infections

,

,

peripheral nervous system diseases

,

ischemic optic neuropathy

,

optic nerve diseases

,

,

,

macular degeneration

,

energy metabolism

,

,

maxillary sinusitis

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

medicated intrauterine devices

,

,

gene expression

,

cell proliferation

,

,

central nervous system neoplasms

,

photoallergic dermatitis

,

phototoxic dermatitis

,

four-dimensional computed tomography

healthy volunteers/patients

,

myeloid leukemia acute

,

myeloid leukemia

,

myelodysplastic syndromes

,

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

congenital abnormalities

,

chromosome aberrations

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

renal cell carcinoma

,

non-small-cell lung carcinoma

,

,

colorectal neoplasms

,

multiple myeloma

,

,

pancreatic neoplasms

,

primary myelofibrosis

,

sjogren's syndrome

,

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

plasma cell neoplasms

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

,

oligodendroglioma

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

chronic hepatitis c

,

chronic hepatitis

,

pancreatic ductal carcinoma

,

,

,

graft rejection

,

,

falciparum malaria

,

,

triple negative breast neoplasms

,

gastrointestinal neoplasms

,

gastrointestinal stromal tumors

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

neoplasm micrometastasis

,

uterine cervical neoplasms

,

,

hematologic neoplasms

,

meningococcal infections

,

,

,

human influenza

,

breast neoplasms

,

,

chronic urticaria

,

,

,

,

haemophilus infections

,

liver transplantation

,

,

,

chronic renal insufficiency

,

kidney diseases

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

psoriatic arthritis

,

,

influenza in birds

,

,

gouty arthritis

,

,

,

autoimmune hepatitis

,

juvenile arthritis

,

h5n1 subtype influenza a virus

,

,

hyperphosphatemia

,

,

communicable diseases

,

,

chronic hepatitis b

,

chronic disease

,

,

cryopyrin-associated periodic syndromes

,

,

lupus nephritis

,

,

,

,

kidney transplantation

,

,

,

tick-borne encephalitis

,

,

,

cystic fibrosis

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