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Company ReportsNeurocrine Biosciences

Neurocrine Biosciences(NBIX)

Neurocrine Biosciences, Inc. is an American biopharmaceutical company founded in 1992. The company is headquartered in San Diego, California, and led by CEO Kevin Gorman. Neurocrine develops treatments for neurological and endocrine-related diseases and disorders. In 2017, the company's drug valbenazine (Ingrezza) was approved in the US to treat adults with tardive dyskinesia (TD).

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Ingrezza	Valbenazine	2017-04-11	2027-2040	Tardive dyskinesia

Clinical Trials

Therapeutic Areas:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

major depressive disorder

,

depressive disorder

,

,

congenital adrenal hyperplasia

,

adrenogenital syndrome

,

adrenocortical hyperfunction

myeloid leukemia acute

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

,

angelman syndrome

,

huntington disease

,

developmental disabilities

,

mental disorders

,

neurodevelopmental disorders

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

non-small-cell lung carcinoma

,

,

muscular atrophy

,

spinal muscular atrophy

,

,

multiple myeloma

,

plasma cell neoplasms

,

follicular lymphoma

,

diabetes mellitus

,

non-hodgkin lymphoma

,

alzheimer disease

,

sickle cell anemia

,

,

type 2 diabetes mellitus

,

paroxysmal hemoglobinuria

,

,

,

obsessive-compulsive disorder

,

compulsive personality disorder

,

brain neoplasms

,

unknown primary neoplasms

,

stomach neoplasms

,

small cell lung carcinoma

,

,

breast neoplasms

,

,

colorectal neoplasms

,

,

triple negative breast neoplasms

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

multiple sclerosis

,

myeloid leukemia

,

rheumatoid arthritis

,

,

chronic renal insufficiency

,

kidney diseases

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

renal cell carcinoma

,

,

,

,

,

,

,

systemic scleroderma

,

diffuse scleroderma

,

,

,

cerebrovascular disorders

,

giant cell arteritis

,

polymyalgia rheumatica

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

chronic hepatitis

,

,

,

,

,

chronic hepatitis c

,

neoplasm metastasis

,

renal insufficiency

,

chronic kidney failure

,

chronic hepatitis b

,

iron-deficiency anemia

,

lymphatic diseases

,

iron deficiencies

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

interstitial lung diseases

,

,

,

acquired immunodeficiency syndrome

,

liver cirrhosis

,

spinal muscular atrophies of childhood

sleep initiation and maintenance disorders

,

,

depressive disorder

,

irritable bowel syndrome

healthy volunteers/patients

,

,

,

cerebellar ataxia

,

friedreich ataxia

,

cognitive dysfunction

hepatic insufficiency

,

renal insufficiency

,

castration-resistant prostatic neoplasms

,

,

,

,

,

unknown primary neoplasms

,

immunomodulation

,

gram-positive bacterial infections

,

t-cell lymphoma peripheral

,

,

merkel cell carcinoma

,

mycosis fungoides

,

clear cell sarcoma

,

myelodysplastic syndromes

,

,

,

pulmonary sarcoidosis

,

lyme neuroborreliosis

,

hypertriglyceridemia

,

,

granuloma annulare

,

mycobacterium avium complex

,

thoracic neoplasms

,

pelvic neoplasms

,

,

,

brain neoplasms

,

stomach neoplasms

,

,

triple negative breast neoplasms

,

head and neck neoplasms

,

urinary bladder neoplasms

,

multiple myeloma

,

neoplasm metastasis

,

ovarian neoplasms

,

thyroid neoplasms

,

,

plasma cell neoplasms

,

small cell lung carcinoma

,

ovarian epithelial carcinoma

,

esophageal neoplasms

,

borrelia infections

,

endometrial neoplasms

,

thyroid diseases

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

uveal neoplasms

,

respiratory syncytial viruses

,

,

,

transitional cell carcinoma

,

kidney diseases

,

small cell carcinoma

,

adenocarcinoma of lung

,

large-cell lymphoma anaplastic

,

,

,

pheochromocytoma

,

,

healthcare-associated pneumonia

,

systemic lupus erythematosus

,

alopecia areata

,

,

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

oligodendroglioma

,

,

hemangioblastoma

,

urogenital neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

germ cell and embryonal neoplasms

,

carcinoid tumor

,

urethral neoplasms

,

ureteral neoplasms

,

alveolar soft part sarcoma

,

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

cholangiocarcinoma

,

gene rearrangement

,

lobular carcinoma

,

plasma cell leukemia

,

medulloblastoma

,

,

rhabdomyosarcoma

,

diffuse intrinsic pontine glioma

,

intraductal carcinoma noninfiltrating

,

b-cell lymphoma

,

cutaneous lupus erythematosus

,

keratoconjunctivitis

,

,

respiratory tract infections

,

,

,

,

hidradenitis suppurativa

,

,

meningococcal infections

,

neoadjuvant therapy

,

diabetes mellitus

,

type 1 diabetes mellitus

,

,

multidrug-resistant tuberculosis

,

von hippel-lindau disease

,

,

,

neurodermatitis

,

,

urologic neoplasms

,

urologic diseases

,

neoplasms by site

,

glandular and epithelial neoplasms

,

,

,

benign fibrous histiocytoma

,

,

malignant fibrous histiocytoma

,

myeloid leukemia accelerated phase

,

,

malignant mesothelioma

,

,

urinary bladder diseases

,

adrenal cortex neoplasms

,

adrenocortical carcinoma

,

second primary neoplasms

,

pulmonary tuberculosis

,

hematologic neoplasms

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

mouth neoplasms

,

,

penile neoplasms

,

plexiform neurofibroma

,

,

testicular neoplasms

,

solitary fibrous tumors

,

,

hemangiopericytoma

,

male urogenital diseases

,

urogenital diseases

,

adenoid cystic carcinoma

,

,

hemangiosarcoma

,

systemic scleroderma

,

diffuse scleroderma

,

,

,

post-acute covid-19 syndrome

,

,

colorectal neoplasms

,

,

atopic dermatitis

,

,

,

,

kidney neoplasms

,

prostatic neoplasms

,

squamous cell carcinoma

,

liver neoplasms

,

pancreatic neoplasms

,

hepatocellular carcinoma

,

,

psoriatic arthritis

,

squamous cell neoplasms

,

squamous cell carcinoma of head and neck

,

,

male breast neoplasms

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

myeloid leukemia chronic-phase

,

juvenile arthritis

,

,

,

bacterial pneumonia

,

,

mycobacterium avium-intracellulare infection

,

immune system diseases

,

inborn genetic diseases

,

genetic skin diseases

,

eczematous skin diseases

,

hypersensitivity

,

immediate hypersensitivity

,

islet cell carcinoma

,

ankylosing spondylitis

,

bacterial infections

,

pancreatic ductal carcinoma

,

,

,

febrile neutropenia

,

,

mycobacterium infections

,

adenosquamous carcinoma

,

large cell carcinoma

,

nervous system diseases

,

optic nerve diseases

,

disease progression

,

cardiovascular diseases

,

immunologic deficiency syndromes

,

breast neoplasms

,

healthy volunteers/patients

,

,

renal cell carcinoma

,

non-small-cell lung carcinoma

,

,

,

rheumatoid arthritis

,

,

,

,

,

acquired immunodeficiency syndrome

,

communicable diseases

,

bcr-abl positive chronic myelogenous leukemia

,

,

ulcerative colitis

,

,

,

myeloid leukemia

,

neuroendocrine tumors

,

gastrointestinal stromal tumors

,

non-hodgkin lymphoma

,

kidney transplantation

,

philadelphia chromosome

,

islet cell adenoma

,

intraabdominal infections

,

mantle-cell lymphoma

,

,

spondylarthritis

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

,

,

,

,

,

ventilator-associated pneumonia

,

chronic hepatitis c

,

,

axial spondyloarthritis

,

,

premature birth

,

bacterial vaginosis

,

vaginal diseases

,

,

infectious skin diseases

,

soft tissue infections

,

,

,

community-acquired infections

,

staphylococcal infections

,

,

hypercholesterolemia

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

bacterial skin diseases

,

,

asymptomatic infections

,

,

,

respiratory tract diseases

renal insufficiency

,

primary myelofibrosis

EZALADCIGENE RESOPARVOVEC

parkinson disease

multiple sclerosis

,

anxiety disorders

,

,

healthy volunteers/patients

,

depressive disorder

,

,

major depressive disorder

,

irritable bowel syndrome

,

healthy volunteers/patients

,

,

thyroid neoplasms

,

thyroid diseases

vitamin d deficiency

,

,

,

depressive disorder

,

bipolar disorder

,

major depressive disorder

,

anxiety disorders

,

,

body-weight trajectory

,

,

diabetes mellitus

,

metabolic syndrome

,

,

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

atrial fibrillation

,

cardiac arrhythmias

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