Crinecerfont
Crinecerfont is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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YTD
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2Y
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
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Completion date
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Commercial
No data
Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hyperplasia | D006965 | EFO_0000536 | — | — | 2 | 2 | — | — | 4 |
| Congenital adrenal hyperplasia | D000312 | — | E25.0 | — | 2 | 2 | — | — | 4 |
| Adrenogenital syndrome | D047808 | — | E25.9 | — | 2 | 2 | — | — | 4 |
| Adrenocortical hyperfunction | D000308 | EFO_1000797 | — | — | 2 | 2 | — | — | 4 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Major depressive disorder | D003865 | EFO_0003761 | F22 | — | 1 | — | — | — | 1 |
| Depressive disorder | D003866 | EFO_1002014 | F32.A | — | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Crinecerfont |
| INN | crinecerfont |
| Description | SSR 125543 is an amine. |
| Classification | Small molecule |
| Drug class | CRF-1 (corticotropin releasing factor) receptor antagonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C#CCN(c1nc(-c2cc(C)c(OC)cc2Cl)c(C)s1)[C@@H](CC1CC1)c1ccc(C)c(F)c1 |
Identifiers
| PDB | — |
| CAS-ID | 752253-39-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL291657 |
| ChEBI ID | 34969 |
| PubChem CID | 5282340 |
| DrugBank | — |
| UNII ID | MFT24BX55I (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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