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Kowa

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Livalo	Pitavastatin	2009-08-03	2024-2031	Hypercholesterolemia , Hypertriglyceridemia , Hyperlipoproteinemias
Seglentis	Celecoxib, Tramadol	2021-10-15	2029-2038	Ankylosing spondylitis , Rheumatoid arthritis , Osteoarthritis , Adenomatous polyposis coli , Dysmenorrhea , Hypertension , Coronary artery disease , Variant angina pectoris , Pain

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

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Status:

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Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

drug interactions

,

,

myeloid leukemia acute

,

b-cell chronic lymphocytic leukemia

,

myeloid leukemia

,

lymphoid leukemia

,

human influenza

,

,

,

,

,

,

breast neoplasms

,

hyperlipoproteinemia type ii

,

,

,

,

hypercholesterolemia

,

hyperlipidemias

,

healthy volunteers/patients

,

,

hyperlipoproteinemias

,

diabetes mellitus

,

coronary disease

,

,

cardiovascular diseases

,

acute coronary syndrome

,

metabolic syndrome

,

coronary artery disease

,

myocardial ischemia

,

myocardial infarction

,

,

,

renal insufficiency

,

type 2 diabetes mellitus

,

kidney diseases

,

inferior wall myocardial infarction

,

,

chronic renal insufficiency

,

angina pectoris

,

atherosclerosis

,

,

oxidative stress

,

glucose intolerance

,

prediabetic state

,

heart disease risk factors

,

,

percutaneous coronary intervention

,

,

glucose metabolism disorders

,

metabolic diseases

,

liver transplantation

,

immunosuppression therapy

,

drug-related side effects and adverse reactions

,

malignant hyperthermia

,

metabolic bone diseases

,

,

postmenopausal osteoporosis

,

vascular calcification

,

,

preconception care

,

alzheimer disease

,

insulin resistance

,

non-alcoholic fatty liver disease

,

,

hypersensitivity

,

,

atherosclerotic plaque

,

carotid artery diseases

,

,

benign paroxysmal positional vertigo

,

,

liver cirrhosis

,

,

,

non-alcoholic fatty liver disease

,

,

biliary liver cirrhosis

,

,

,

,

retinal diseases

,

diabetic retinopathy

,

type 2 diabetes mellitus

,

diabetes mellitus

,

hyperlipidemias

,

hypercholesterolemia

diabetic nephropathies

,

kidney diseases

,

type 2 diabetes mellitus

,

diabetes mellitus

,

diabetes complications

,

,

non-alcoholic fatty liver disease

,

renal insufficiency

,

type 2 diabetes mellitus

,

diabetes mellitus

,

diabetes complications

,

coronary disease

,

coronary artery disease

,

hematologic diseases

Tofogliflozin anhydrous

healthy volunteers/patients

,

diabetic nephropathies

,

kidney diseases

,

liver cirrhosis

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

non-alcoholic fatty liver disease

,

,

,

allergic rhinitis

,

,

allergic conjunctivitis

,

liver neoplasms

,

atopic dermatitis

,

,

healthy volunteers/patients

,

,

,

,

,

prostatic neoplasms

,

postoperative nausea and vomiting

,

,

brain neoplasms

,

second primary neoplasms

,

,

treatment-resistant depressive disorder

,

depressive disorder

,

esophageal neoplasms

,

esophageal squamous cell carcinoma

,

hematologic neoplasms

,

,

pseudomonas infections

,

pseudomonas aeruginosa

,

,

renal cell carcinoma

,

liver cirrhosis

,

experimental liver cirrhosis

,

chronic obstructive pulmonary disease

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

ovarian epithelial carcinoma

,

,

colorectal neoplasms

,

pancreatic ductal carcinoma

,

gastrointestinal neoplasms

,

biliary tract neoplasms

,

non-small-cell lung carcinoma

,

,

,

,

acquired immunodeficiency syndrome

,

ovarian neoplasms

,

breast neoplasms

,

,

hepatocellular carcinoma

,

,

immunologic deficiency syndromes

,

,

antibiotic prophylaxis

,

,

chronic hepatitis b

,

uterine cervical neoplasms

,

condylomata acuminata

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

cystic fibrosis

,

pulmonary hypertension

,

pulmonary arterial hypertension

,

endometrial neoplasms

,

,

triple negative breast neoplasms

,

,

chronic hepatitis c

,

,

,

,

,

neuromuscular blockade

,

chronic kidney failure

,

kidney diseases

,

chronic hepatitis

,

,

intestinal diseases

,

non-hodgkin lymphoma

,

,

,

traumatic brain injuries

,

brain concussion

,

,

post-concussion syndrome

type 2 diabetes mellitus

,

diabetes mellitus

,

healthy volunteers/patients

,

,

,

,

,

chronic renal insufficiency

,

chronic kidney failure

,

kidney diseases

,

,

renal insufficiency

,

heart disease risk factors

,

prediabetic state

,

,

cardiovascular diseases

,

open-angle glaucoma

,

alzheimer disease

,

,

myocardial infarction

,

,

,

renal cell carcinoma

,

ovarian neoplasms

,

urinary bladder neoplasms

,

fallopian tube neoplasms

,

,

ovarian epithelial carcinoma

,

,

,

barrett esophagus

,

chronic progressive multiple sclerosis

,

vitamin d deficiency

,

hypersensitivity

,

oral lichen planus

,

,

epidermolysis bullosa

,

,

,

,

,

sleep apnea syndromes

,

vestibular diseases

,

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

,

retinal diseases

,

diabetic retinopathy

,

,

stomach neoplasms

,

pancreatic neoplasms

,

,

,

multiple sclerosis

,

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

bipolar disorder

,

,

,

non-small-cell lung carcinoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

second primary neoplasms

,

type 2 diabetes mellitus

,

chromosome deletion

,

type 1 diabetes mellitus

,

diastolic heart failure

,

,

cystic fibrosis

,

,

renal insufficiency

,

squamous cell carcinoma

,

squamous cell neoplasms

,

,

post-acute covid-19 syndrome

,

,

,

burkitt lymphoma

,

,

thrombocytopenia

,

,

lactic acidosis

,

,

mantle-cell lymphoma

,

lymphoid leukemia

,

aids-related lymphoma

,

spinal cord injuries

,

prader-willi syndrome

,

post-cardiac arrest syndrome

,

,

pulmonary tuberculosis

,

rectal neoplasms

,

cri-du-chat syndrome

,

macrocytic anemia

,

,

chronic hepatitis b

,

,

chronic hepatitis

,

,

atopic dermatitis

,

,

,

,

noise-induced hearing loss

,

,

,

sudden death cardiac

,

,

basal cell carcinoma

,

nerve compression syndromes

,

,

charcot-marie-tooth disease

,

hereditary sensory and motor neuropathy

,

,

bipolar and related disorders

,

,

,

metabolic diseases

,

,

glycogen storage disease type ii

,

lysosomal storage diseases

,

glycogen storage disease

,

,

,

,

mitochondrial diseases

,

healthy volunteers/patients

,

parkinson disease

,

colorectal neoplasms

,

chronic fatigue syndrome

,

,

,

breast neoplasms

,

coronary artery disease

,

,

polycystic ovary syndrome

,

prostatic neoplasms

,

cerebellar ataxia

,

huntington disease

,

myocardial ischemia

,

,

,

,

friedreich ataxia

,

,

,

progressive supranuclear palsy

,

duchenne muscular dystrophy

,

muscular dystrophies

,

myelodysplastic syndromes

,

coronary disease

,

drug-related side effects and adverse reactions

,

non-alcoholic fatty liver disease

,

,

cognitive dysfunction

,

cholangiocarcinoma

,

liver neoplasms

,

neoplasm metastasis

,

,

biliary tract neoplasms

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

,

,

persian gulf syndrome

,

,

hyperlipidemias

,

hyperlipoproteinemias

,

,

,

gastrointestinal neoplasms

,

neuroendocrine tumors

,

carcinoid tumor

,

paraneoplastic syndromes

,

islet cell adenoma

,

malignant carcinoid syndrome

,

rem sleep behavior disorder

,

mental disorders

,

headache disorders

,

nervous system diseases

,

hepatocellular carcinoma

,

gallbladder neoplasms

,

ampulla of vater cancer

,

pathologic dilatation

,

,

corneal diseases

,

,

multiple organ failure

,

,

,

limb-girdle muscular dystrophies

,

,

coronary artery bypass

,

cardiac valve annuloplasty

,

,

coronary stenosis

,

,

juvenile arthritis

,

,

,

,

myotonic dystrophy

,

,

,

cardiovascular diseases

,

male infertility

,

hypercholesterolemia

,

,

migraine disorders

,

diabetes mellitus

,

metabolic syndrome

,

oxidative stress

,

kidney diseases

,

,

atherosclerosis

,

,

,

,

chronic kidney failure

,

insulin resistance

,

,

,

,

hypertriglyceridemia

,

,

chronic renal insufficiency

,

critical illness

,

,

opioid-related disorders

,

morphine dependence

,

,

,

,

,

muscle weakness

,

cardiomyopathies

,

dilated cardiomyopathy

,

,

severe acute respiratory syndrome-related coronavirus

,

severe acute respiratory syndrome

,

,

,

,

temporomandibular joint disorders

,

,

temporomandibular joint dysfunction syndrome

,

acute coronary syndrome

,

attitudes health knowledge practice

,

postoperative pain

,

periodontal diseases

,

,

,

,

,

muscular diseases

,

depressive disorder

,

,

myofascial pain syndromes

,

,

,

medication adherence

,

chromosome disorders

,

autistic disorder

,

autism spectrum disorder

,

,

fetal growth retardation

,

premature birth

,

iron deficiencies

,

vitamin b 12 deficiency

,

,

dermatomyositis

,

,

female infertility

,

,

cardiovascular abnormalities

,

ascorbic acid deficiency

,

ovarian reserve

,

vascular remodeling

,

macular degeneration

,

wet macular degeneration

,

,

post-concussion syndrome

,

gestational diabetes

,

pregnancy outcome

,

gingival recession

,

acute kidney injury

,

intellectual disability

,

hepatic encephalopathy

,

psychotic disorders

,

health status indicators

,

aphthous stomatitis

,

,

,

,

attention deficit disorder with hyperactivity

,

,

mitochondrial genome

,

reproductive physiological phenomena

,

inborn genetic diseases

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

spontaneous abortion

,

,

kidney transplantation

,

ischemic preconditioning

,

,

respiratory tract infections

,

encephalomyelitis

,

dietary supplements

,

,

,

dental implants

,

,

,

chronic periodontitis

,

,

,

,

physical fitness

,

liver cirrhosis

,

,

st elevation myocardial infarction

,

,

healthy volunteers/patients

,

renal insufficiency

,

critical illness

,

parkinson disease

,

,

cystic fibrosis

,

,

pituitary dwarfism

,

,

cardiovascular diseases

,

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

gestational diabetes

,

nutrition disorders

,

cardiac surgical procedures

,

,

,

,

diabetes mellitus

,

type 2 diabetes mellitus

,

type 1 diabetes mellitus

,

drug delivery systems

,

,

,

,

,

insulin resistance

,

body weight changes

,

atherosclerosis

,

arteriosclerosis

,

,

,

,

,

diabetic ketoacidosis

,

chronic renal insufficiency

,

kidney diseases

,

respiratory insufficiency

,

surgical wound infection

,

latent autoimmune diabetes in adults

,

,

heart disease risk factors

,

,

patient participation

Microcrystalline cellulose

hematologic diseases

healthy volunteers/patients

,

renal insufficiency

,

critical illness

,

parkinson disease

,

,

cystic fibrosis

,

,

pituitary dwarfism

,

,

cardiovascular diseases

,

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

gestational diabetes

,

nutrition disorders

,

cardiac surgical procedures

,

,

,

,

diabetes mellitus

,

type 2 diabetes mellitus

,

type 1 diabetes mellitus

,

drug delivery systems

,

,

,

,

,

insulin resistance

,

body weight changes

,

atherosclerosis

,

arteriosclerosis

,

,

,

,

,

diabetic ketoacidosis

,

chronic renal insufficiency

,

kidney diseases

,

respiratory insufficiency

,

surgical wound infection

,

latent autoimmune diabetes in adults

,

,

heart disease risk factors

,

,

patient participation

,

craniocerebral trauma

,

diabetes mellitus

,

,

oxidative stress

,

type 2 diabetes mellitus

,

,

cystic fibrosis

,

,

central serous chorioretinopathy

,

alzheimer disease

,

,

retinal diseases

,

diabetic retinopathy

,

,

mitochondrial diseases

,

,

epiretinal membrane

,

retinal perforations

,

macular degeneration

,

,

open-angle glaucoma

,

,

,

healthy volunteers/patients

,

dry eye syndromes

,

hyperlipidemias

,

keratoconjunctivitis sicca

,

wet macular degeneration

,

hyperlipoproteinemias

,

,

,

,

choroidal neovascularization

,

pathologic neovascularization

,

,

skin pigmentation

,

skin abnormalities

,

,

impulsive behavior

,

coronary artery disease

,

metabolic syndrome

,

premature birth

,

type 1 diabetes mellitus

,

,

,

oculocutaneous albinism

,

,

ocular albinism

,

cognitive dysfunction

,

behavior and behavior mechanisms

,

,

entoptic vision

,

,

cognition disorders

,

abetalipoproteinemia

,

,

vision disorders

,

,

,

retinal degeneration

,

,

,

,

nutritional status

alzheimer disease

1

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