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Kowa

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Livalo	Pitavastatin	2009-08-03	2024-2031	Hypercholesterolemia , Hypertriglyceridemia , Hyperlipoproteinemias
Seglentis	Celecoxib, Tramadol	2021-10-15	2029-2038	Ankylosing spondylitis , Rheumatoid arthritis , Osteoarthritis , Adenomatous polyposis coli , Dysmenorrhea , Hypertension , Coronary artery disease , Variant angina pectoris , Pain

Clinical Trials

Therapeutic Areas:

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Status:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

drug interactions

,

,

myeloid leukemia acute

,

b-cell chronic lymphocytic leukemia

,

myeloid leukemia

,

lymphoid leukemia

,

human influenza

,

,

sickle cell anemia

,

,

,

,

,

,

breast neoplasms

,

hyperlipoproteinemia type ii

,

,

,

,

hypercholesterolemia

,

hyperlipidemias

,

healthy volunteers/patients

,

,

hyperlipoproteinemias

,

diabetes mellitus

,

coronary disease

,

,

cardiovascular diseases

,

acute coronary syndrome

,

metabolic syndrome

,

coronary artery disease

,

myocardial ischemia

,

myocardial infarction

,

,

,

renal insufficiency

,

type 2 diabetes mellitus

,

kidney diseases

,

inferior wall myocardial infarction

,

,

chronic renal insufficiency

,

angina pectoris

,

atherosclerosis

,

,

oxidative stress

,

glucose intolerance

,

prediabetic state

,

heart disease risk factors

,

,

percutaneous coronary intervention

,

,

glucose metabolism disorders

,

metabolic diseases

,

liver transplantation

,

immunosuppression therapy

,

drug-related side effects and adverse reactions

,

malignant hyperthermia

,

metabolic bone diseases

,

,

postmenopausal osteoporosis

,

vascular calcification

,

,

preconception care

,

alzheimer disease

,

insulin resistance

,

non-alcoholic fatty liver disease

,

,

hypersensitivity

,

,

atherosclerotic plaque

,

carotid artery diseases

,

,

benign paroxysmal positional vertigo

,

,

cocaine-related disorders

,

addictive behavior

,

,

chemotherapy-induced febrile neutropenia

,

breast neoplasms

liver cirrhosis

,

,

,

non-alcoholic fatty liver disease

,

,

biliary liver cirrhosis

,

,

,

,

retinal diseases

,

diabetic retinopathy

,

type 2 diabetes mellitus

,

diabetes mellitus

,

hyperlipidemias

,

hypercholesterolemia

von willebrand diseases

,

type 2 diabetes mellitus

,

diabetes mellitus

renal insufficiency

,

type 2 diabetes mellitus

Tofogliflozin anhydrous

type 2 diabetes mellitus

,

diabetes mellitus

hyperlipidemias

,

gastrointestinal stromal tumors

,

,

iron-deficiency anemia

,

iron deficiencies

,

,

,

,

small cell lung carcinoma

,

healthy volunteers/patients

,

,

primary myelofibrosis

,

myeloid leukemia acute

,

myeloid leukemia

,

,

hepatocellular carcinoma

,

,

plexiform neurofibroma

,

neurofibromatoses

,

,

,

,

chronic obstructive pulmonary disease

,

,

triple negative breast neoplasms

,

,

,

essential thrombocythemia

,

polycythemia vera

,

,

,

lupus nephritis

,

,

inflammatory breast neoplasms

,

prostatic neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

wiskott-aldrich syndrome

,

bcr-abl positive chronic myelogenous leukemia

,

,

graft vs host disease

,

hematopoietic stem cell transplantation

,

bronchiolitis obliterans syndrome

,

,

hyperlipoproteinemia type ii

,

organ transplantation

,

homozygous familial hypercholesterolemia

,

cryopyrin-associated periodic syndromes

,

myelodysplastic syndromes

,

,

liver transplantation

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

parkinson disease

,

,

,

juvenile arthritis

,

,

,

,

hepatitis b virus

,

,

,

,

vision disorders

,

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

,

acute coronary syndrome

,

,

,

pulmonary eosinophilia

,

pancreatic neoplasms

,

,

,

kidney transplantation

,

,

hypercholesterolemia

,

,

cardiovascular diseases

,

atherosclerosis

,

chronic kidney failure

,

kidney diseases

,

thrombocytopenia

,

breast neoplasms

,

,

renal insufficiency

,

,

,

,

chronic renal insufficiency

,

,

renal replacement therapy

,

drug-related side effects and adverse reactions

,

heart transplantation

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

,

cystic fibrosis

,

pseudomonas infections

,

type 2 diabetes mellitus

,

diabetes mellitus

,

multiple myeloma

,

plasma cell neoplasms

,

transplantation

,

cytomegalovirus infections

,

communicable diseases

,

metabolic syndrome

,

preconception care

,

drug interactions

,

percutaneous coronary intervention

,

,

kidney diseases

,

retinal diseases

,

kidney transplantation

parkinson disease

,

central nervous system diseases

,

,

nervous system diseases

,

movement disorders

,

neurodegenerative diseases

,

,

,

colorectal neoplasms

,

,

non-small-cell lung carcinoma

,

head and neck neoplasms

,

esophageal neoplasms

,

,

,

,

,

pulmonary hypertension

,

pulmonary arterial hypertension

,

,

pulmonary edema

,

squamous cell carcinoma

,

squamous cell neoplasms

,

prostatic neoplasms

,

breast neoplasms

,

,

,

ovarian neoplasms

,

acquired immunodeficiency syndrome

,

communicable diseases

,

,

,

,

premature obstetric labor

,

,

,

,

,

ovarian epithelial carcinoma

,

overactive urinary bladder

,

non-small-cell lung carcinoma

,

chronic renal insufficiency

,

kidney diseases

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

,

,

head and neck neoplasms

,

renal cell carcinoma

,

,

urinary tract infections

,

non-hodgkin lymphoma

,

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

erectile dysfunction

,

,

,

muscle spasticity

,

urinary incontinence

,

,

,

postmenopausal osteoporosis

,

stomach neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

acute coronary syndrome

,

,

parkinson disease

,

human influenza

,

,

,

brain neoplasms

,

neoplasm metastasis

,

small cell lung carcinoma

,

,

venous thrombosis

,

thrombophlebitis

,

,

postoperative nausea and vomiting

,

post-traumatic stress disorders

,

traumatic stress disorders

,

,

,

,

triple negative breast neoplasms

,

endometrial neoplasms

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

immunologic deficiency syndromes

,

uterine cervical neoplasms

,

atherosclerosis

,

,

,

b-cell lymphoma

,

systemic lupus erythematosus

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

,

ovarian neoplasms

,

serous cystadenocarcinoma

,

fallopian tube neoplasms

,

,

hereditary breast and ovarian cancer syndrome

,

mullerian mixed tumor

,

open-angle glaucoma

,

alzheimer disease

,

,

myocardial infarction

,

,

,

renal cell carcinoma

,

ovarian neoplasms

,

urinary bladder neoplasms

,

fallopian tube neoplasms

,

,

ovarian epithelial carcinoma

,

,

,

barrett esophagus

,

chronic progressive multiple sclerosis

,

vitamin d deficiency

,

hypersensitivity

,

oral lichen planus

,

,

epidermolysis bullosa

,

,

,

,

,

sleep apnea syndromes

,

vestibular diseases

,

,

peripheral nervous system diseases

,

,

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

,

retinal diseases

,

diabetic retinopathy

,

stomach neoplasms

,

pancreatic neoplasms

,

,

,

multiple sclerosis

,

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

bipolar disorder

,

post-acute covid-19 syndrome

,

,

,

non-small-cell lung carcinoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

second primary neoplasms

,

type 2 diabetes mellitus

,

chromosome deletion

,

autistic disorder

,

autism spectrum disorder

,

type 1 diabetes mellitus

,

diastolic heart failure

,

,

cystic fibrosis

,

,

renal insufficiency

,

squamous cell carcinoma

,

squamous cell neoplasms

,

,

,

,

burkitt lymphoma

,

,

thrombocytopenia

,

,

lactic acidosis

,

,

mantle-cell lymphoma

,

lymphoid leukemia

,

aids-related lymphoma

,

spinal cord injuries

,

prader-willi syndrome

,

post-cardiac arrest syndrome

,

,

pulmonary tuberculosis

,

rectal neoplasms

,

cri-du-chat syndrome

,

macrocytic anemia

,

,

chronic hepatitis b

,

,

chronic hepatitis

,

,

atopic dermatitis

,

,

,

,

noise-induced hearing loss

,

,

,

sudden death cardiac

,

,

basal cell carcinoma

,

nerve compression syndromes

,

,

charcot-marie-tooth disease

,

hereditary sensory and motor neuropathy

,

,

bipolar and related disorders

,

,

,

metabolic diseases

,

,

glycogen storage disease type ii

,

lysosomal storage diseases

,

glycogen storage disease

,

,

pervasive child development disorders

,

,

,

mitochondrial diseases

,

healthy volunteers/patients

,

parkinson disease

,

colorectal neoplasms

,

chronic fatigue syndrome

,

,

,

breast neoplasms

,

coronary artery disease

,

,

polycystic ovary syndrome

,

prostatic neoplasms

,

cerebellar ataxia

,

huntington disease

,

myocardial ischemia

,

,

,

,

friedreich ataxia

,

,

,

progressive supranuclear palsy

,

duchenne muscular dystrophy

,

muscular dystrophies

,

myelodysplastic syndromes

,

coronary disease

,

drug-related side effects and adverse reactions

,

non-alcoholic fatty liver disease

,

,

cognitive dysfunction

,

cholangiocarcinoma

,

liver neoplasms

,

neoplasm metastasis

,

,

biliary tract neoplasms

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

,

,

persian gulf syndrome

,

,

hyperlipidemias

,

hyperlipoproteinemias

,

,

,

gastrointestinal neoplasms

,

neuroendocrine tumors

,

carcinoid tumor

,

paraneoplastic syndromes

,

islet cell adenoma

,

malignant carcinoid syndrome

,

rem sleep behavior disorder

,

mental disorders

,

headache disorders

,

nervous system diseases

,

hepatocellular carcinoma

,

gallbladder neoplasms

,

ampulla of vater cancer

,

pathologic dilatation

,

,

corneal diseases

,

,

multiple organ failure

,

,

,

limb-girdle muscular dystrophies

,

,

coronary artery bypass

,

cardiac valve annuloplasty

,

,

coronary stenosis

,

,

juvenile arthritis

,

,

,

,

myotonic dystrophy

,

,

,

cardiovascular diseases

,

male infertility

,

hypercholesterolemia

,

,

migraine disorders

,

diabetes mellitus

,

metabolic syndrome

,

oxidative stress

,

kidney diseases

,

,

atherosclerosis

,

,

,

,

chronic kidney failure

,

insulin resistance

,

,

,

,

hypertriglyceridemia

,

,

chronic renal insufficiency

,

critical illness

,

,

,

opioid-related disorders

,

morphine dependence

,

,

,

,

,

muscle weakness

,

cardiomyopathies

,

dilated cardiomyopathy

,

severe acute respiratory syndrome-related coronavirus

,

severe acute respiratory syndrome

,

,

,

,

temporomandibular joint disorders

,

,

temporomandibular joint dysfunction syndrome

,

acute coronary syndrome

,

attitudes health knowledge practice

,

postoperative pain

,

periodontal diseases

,

,

,

,

,

muscular diseases

,

depressive disorder

,

,

myofascial pain syndromes

,

,

,

medication adherence

,

chromosome disorders

,

,

fetal growth retardation

,

premature birth

,

iron deficiencies

,

vitamin b 12 deficiency

,

,

dermatomyositis

,

,

female infertility

,

,

cardiovascular abnormalities

,

ascorbic acid deficiency

,

ovarian reserve

,

vascular remodeling

,

macular degeneration

,

wet macular degeneration

,

,

post-concussion syndrome

,

gestational diabetes

,

pregnancy outcome

,

gingival recession

,

acute kidney injury

,

intellectual disability

,

hepatic encephalopathy

,

psychotic disorders

,

health status indicators

,

aphthous stomatitis

,

,

,

,

attention deficit disorder with hyperactivity

,

,

mitochondrial genome

,

reproductive physiological phenomena

,

inborn genetic diseases

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

spontaneous abortion

,

,

kidney transplantation

,

ischemic preconditioning

,

,

respiratory tract infections

,

encephalomyelitis

,

dietary supplements

,

,

,

dental implants

,

,

,

chronic periodontitis

,

,

,

,

physical fitness

,

liver cirrhosis

,

,

st elevation myocardial infarction

,

,

communicable diseases

,

parkinson disease

,

central nervous system diseases

,

,

nervous system diseases

,

movement disorders

,

neurodegenerative diseases

,

,

,

colorectal neoplasms

,

,

non-small-cell lung carcinoma

,

head and neck neoplasms

,

esophageal neoplasms

,

,

1

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