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Kowa

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Livalo	Pitavastatin	2009-08-03	2024-2031	Hypercholesterolemia , Hypertriglyceridemia , Hyperlipoproteinemias
Seglentis	Celecoxib, Tramadol	2021-10-15	2029-2038	Ankylosing spondylitis , Rheumatoid arthritis , Osteoarthritis , Adenomatous polyposis coli , Dysmenorrhea , Hypertension , Coronary artery disease , Variant angina pectoris , Pain

Clinical Trials

Therapeutic Areas:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

drug interactions

,

non-alcoholic fatty liver disease

,

myeloid leukemia acute

,

,

b-cell chronic lymphocytic leukemia

,

human influenza

,

,

,

,

non-small-cell lung carcinoma

,

pancreatic neoplasms

,

retinitis pigmentosa

,

,

,

ischemic stroke

,

,

,

breast neoplasms

,

hyperlipoproteinemia type ii

,

,

,

,

,

hypercholesterolemia

,

hyperlipidemias

,

healthy volunteers/patients

,

,

diabetes mellitus

,

cardiovascular diseases

,

acute coronary syndrome

,

coronary disease

,

,

hyperlipoproteinemias

,

metabolic syndrome

,

myocardial infarction

,

coronary artery disease

,

myocardial ischemia

,

renal insufficiency

,

atherosclerosis

,

,

type 2 diabetes mellitus

,

kidney diseases

,

,

inferior wall myocardial infarction

,

,

,

chronic renal insufficiency

,

angina pectoris

,

oxidative stress

,

glucose intolerance

,

prediabetic state

,

heart disease risk factors

,

,

percutaneous coronary intervention

,

,

glucose metabolism disorders

,

metabolic diseases

,

liver transplantation

,

immunosuppression therapy

,

drug-related side effects and adverse reactions

,

malignant hyperthermia

,

metabolic bone diseases

,

,

postmenopausal osteoporosis

,

vascular calcification

,

,

preconception care

,

alzheimer disease

,

insulin resistance

,

,

hypersensitivity

,

,

atherosclerotic plaque

,

carotid artery diseases

,

,

benign paroxysmal positional vertigo

,

,

pancreatic neoplasms

,

hereditary sensory and autonomic neuropathies

,

essential thrombocythemia

,

polycythemia vera

,

primary myelofibrosis

,

,

,

diabetic nephropathies

,

kidney diseases

,

atopic dermatitis

,

,

alopecia areata

,

liver cirrhosis

,

,

,

non-alcoholic fatty liver disease

,

biliary liver cirrhosis

,

,

,

,

,

diabetic retinopathy

,

type 2 diabetes mellitus

,

hyperlipidemias

,

hypercholesterolemia

,

,

hypertriglyceridemia

,

healthy volunteers/patients

,

type 2 diabetes mellitus

,

diabetes complications

,

non-alcoholic fatty liver disease

,

diabetes mellitus

renal insufficiency

,

type 2 diabetes mellitus

Tofogliflozin anhydrous

healthy volunteers/patients

,

renal insufficiency

,

diabetes mellitus

,

type 2 diabetes mellitus

healthy volunteers/patients

,

colorectal neoplasms

,

chronic renal insufficiency

,

kidney diseases

,

sickle cell anemia

,

knee osteoarthritis

,

,

,

,

ovarian neoplasms

,

,

ovarian epithelial carcinoma

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

laryngeal neoplasms

,

opioid-related disorders

,

,

coronavirus infections

,

,

,

brain neoplasms

,

,

neurofibromatosis 2

,

acoustic neuroma

,

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

,

cystic fibrosis

,

,

soft tissue neoplasms

,

biliary tract neoplasms

,

,

urinary bladder neoplasms

,

invasive hydatidiform mole

,

non-muscle invasive bladder neoplasms

,

non-hodgkin lymphoma

,

b-cell chronic lymphocytic leukemia

,

mantle-cell lymphoma

,

b-cell lymphoma

,

b-cell leukemia

,

diabetes mellitus

,

chronic obstructive pulmonary disease

,

,

non-small-cell lung carcinoma

,

,

pulmonary eosinophilia

,

,

,

,

,

endometrial neoplasms

,

borderline personality disorder

,

personality disorders

,

churg-strauss syndrome

,

eosinophilic granuloma

,

type 2 diabetes mellitus

,

breast neoplasms

,

,

,

,

endomyocardial fibrosis

,

postoperative pain

,

,

major depressive disorder

,

depressive disorder

,

systemic lupus erythematosus

acquired immunodeficiency syndrome

,

aids-related complex

,

,

,

neuromyelitis optica

,

hematologic diseases

,

immunoproliferative disorders

,

transitional cell carcinoma

,

b-cell leukemia

,

,

transverse myelitis

,

psoriatic arthritis

,

bites and stings

,

pathologic processes

,

,

diffuse intrinsic pontine glioma

,

infectious pregnancy complications

,

renal insufficiency

,

thyroid neoplasms

,

parotid neoplasms

,

neovascular glaucoma

,

intraocular lymphoma

,

eosinophilic esophagitis

,

,

hiv seronegativity

,

hereditary hemorrhagic telangiectasia

,

,

,

open-angle glaucoma

,

,

,

,

communicable diseases

,

,

,

hemangioblastoma

,

von hippel-lindau disease

,

acute lung injury

,

newborn respiratory distress syndrome

,

ischemic stroke

,

cerebral infarction

,

brain neoplasms

,

,

,

,

large b-cell lymphoma diffuse

,

,

stomach neoplasms

,

esophageal neoplasms

,

,

prostatic neoplasms

,

,

,

endometrial neoplasms

,

head and neck neoplasms

,

hypersensitivity

,

multiple myeloma

,

kidney neoplasms

,

urinary bladder neoplasms

,

retinal diseases

,

hodgkin disease

,

peritoneal neoplasms

,

uterine cervical neoplasms

,

salivary gland neoplasms

,

biliary tract neoplasms

,

small cell lung carcinoma

,

pancreatic ductal carcinoma

,

,

hemangiosarcoma

,

polypoidal choroidal vasculopathy

,

b-cell lymphoma marginal zone

,

,

central nervous system neoplasms

,

plasma cell neoplasms

,

basal cell carcinoma

,

,

malignant fibrous histiocytoma

,

,

relapsing-remitting multiple sclerosis

,

meningeal neoplasms

,

meningeal carcinomatosis

,

animal mammary neoplasms

,

lymphoproliferative disorders

,

lymphatic diseases

,

hematologic neoplasms

,

,

focal segmental glomerulosclerosis

,

respiratory distress syndrome

,

,

squamous cell carcinoma of head and neck

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

,

,

oligodendroglioma

,

unknown primary neoplasms

,

cholangiocarcinoma

,

radiation injuries

,

diabetic retinopathy

,

,

basal cell neoplasms

,

,

benign fibrous histiocytoma

,

local neoplasm recurrence

,

left ventricular dysfunction

,

reactive arthritis

,

urologic neoplasms

,

osteitis deformans

,

congenital heart defects

,

protein-losing enteropathies

,

immunoglobulin light-chain amyloidosis

,

proteostasis deficiencies

,

male breast neoplasms

,

medulloblastoma

,

primitive neuroectodermal tumors

,

infratentorial neoplasms

,

retinal degeneration

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

myeloid leukemia acute

,

,

respiratory insufficiency

,

severe acute respiratory syndrome

,

,

neurofibrosarcoma

,

gastrointestinal stromal tumors

,

kidney diseases

,

,

interstitial nephritis

,

adrenocortical carcinoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

burkitt lymphoma

,

large-cell lymphoma immunoblastic

,

churg-strauss syndrome

,

bronchiolitis obliterans syndrome

,

,

,

digestive system neoplasms

,

,

,

thymus neoplasms

,

precancerous conditions

,

monoclonal gammopathy of undetermined significance

,

neurofibromatosis 2

,

acoustic neuroma

,

cutaneous malignant melanoma

,

peripheral nervous system diseases

,

myasthenia gravis

,

,

vaginal neoplasms

,

vulvar neoplasms

,

gallbladder neoplasms

,

basal cell nevus syndrome

,

tongue neoplasms

,

,

dermatomyositis

,

,

pseudotumor cerebri

,

,

orbital pseudotumor

,

lymphadenopathy

,

,

autoimmune pancreatitis

,

retroperitoneal fibrosis

,

antiphospholipid syndrome

,

uterine neoplasms

,

central nervous system diseases

,

,

st elevation myocardial infarction

,

inferior wall myocardial infarction

,

,

synovial sarcoma

,

myxoid liposarcoma

,

hereditary sensory and autonomic neuropathies

,

,

,

orbital diseases

,

,

ocular motility disorders

,

,

opsoclonus-myoclonus syndrome

,

neuroendocrine carcinoma

,

hairy cell leukemia

,

spinocerebellar degenerations

,

chronic obstructive pulmonary disease

,

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

,

non-hodgkin lymphoma

,

,

neoplasm metastasis

,

ovarian neoplasms

,

b-cell chronic lymphocytic leukemia

,

fallopian tube neoplasms

,

b-cell lymphoma

,

rheumatoid arthritis

,

renal cell carcinoma

,

pancreatic neoplasms

,

colonic neoplasms

,

,

rectal neoplasms

,

,

lymphoid leukemia

,

follicular lymphoma

,

ovarian epithelial carcinoma

,

,

triple negative breast neoplasms

,

chronic urticaria

,

,

diabetes mellitus

,

,

peanut hypersensitivity

,

,

multiple sclerosis

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

kidney transplantation

,

neuroendocrine tumors

,

lupus nephritis

,

vision disorders

,

systemic lupus erythematosus

,

hypopituitarism

,

cystic fibrosis

,

central venous catheters

,

venous thrombosis

,

postthrombotic syndrome

,

thrombotic thrombocytopenic purpura

,

,

carcinoid tumor

,

,

paraneoplastic syndromes

,

islet cell carcinoma

,

islet cell adenoma

,

,

,

somatostatinoma

,

,

chronic progressive multiple sclerosis

,

venous thromboembolism

,

postphlebitic syndrome

,

nephrotic syndrome

,

,

diffuse cerebral sclerosis of schilder

,

interstitial lung diseases

,

pleural effusion

,

,

colorectal neoplasms

,

macular degeneration

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

choroidal neovascularization

,

retinal vein occlusion

,

healthy volunteers/patients

,

pituitary dwarfism

,

granulomatosis with polyangiitis

,

microscopic polyangiitis

,

,

,

,

chronic kidney failure

,

,

,

myocardial infarction

,

,

,

,

primary ovarian insufficiency

,

,

turner syndrome

,

gonadal dysgenesis

,

premature menopause

,

chronic renal insufficiency

,

failure to thrive

,

pulmonary embolism

,

,

iga glomerulonephritis

,

bullous pemphigoid

,

retinal neovascularization

,

growth disorders

,

sickle cell anemia

,

atopic dermatitis

,

,

kaposi varicelliform eruption

,

,

,

,

thromboembolism

,

hereditary angioedemas

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

parkinson disease

,

respiratory tract infections

,

,

communicable diseases

,

drug-related side effects and adverse reactions

,

kidney transplantation

prostatic neoplasms

,

,

,

,

neoplasm metastasis

,

rheumatoid arthritis

,

hypertrophic pyloric stenosis

,

vascular diseases

,

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