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Company ReportsBioLineRx

BioLineRx

BioLineRx (Hebrew: ביוליין אר אקס), or BioLine, is a publicly traded drug development company. Headquartered in Israel, its shares are traded on the NASDAQ Capital Market and on the Tel Aviv Stock Exchange.

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Aphexda	Motixafortide	2023-09-08		Hematopoietic stem cell mobilization

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hematopoietic stem cell mobilization

,

healthy volunteers/patients

,

sickle cell anemia

,

myeloid leukemia acute

,

,

myeloid leukemia

,

myelodysplastic syndromes

,

esophageal neoplasms

,

aplastic anemia

,

pancreatic neoplasms

,

hematologic neoplasms

,

myeloproliferative disorders

,

non-hodgkin lymphoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

hodgkin disease

,

multiple myeloma

breast neoplasms

prostatic hyperplasia

,

healthy volunteers/patients

,

respiratory tract diseases

,

respiration disorders

,

,

kidney diseases

,

,

,

,

,

respiratory tract infections

,

,

premature obstetric labor

,

,

pulmonary edema

,

,

bacterial infections

,

,

hepatic insufficiency

,

,

non-alcoholic fatty liver disease

,

,

multiple myeloma

,

,

,

,

breast neoplasms

,

,

pulmonary tuberculosis

,

atherosclerosis

,

obstructive lung diseases

,

plasma cell neoplasms

,

,

pancreatic neoplasms

,

,

follicular lymphoma

,

allergic rhinitis

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

sjogren's syndrome

,

,

,

,

,

systemic lupus erythematosus

,

,

,

acquired immunodeficiency syndrome

,

,

type 2 diabetes mellitus

,

human influenza

,

communicable diseases

,

,

,

parkinson disease

,

,

migraine disorders

,

,

major depressive disorder

,

depressive disorder

,

churg-strauss syndrome

,

granulomatosis with polyangiitis

,

systemic vasculitis

,

eosinophilic granuloma

,

neisseria meningitidis

,

haemophilus influenzae type b

,

restless legs syndrome

,

psychomotor agitation

,

,

hypereosinophilic syndrome

,

,

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

urinary tract infections

,

,

respiratory syncytial virus infections

,

,

chronic obstructive pulmonary disease

,

,

diabetes mellitus

,

,

,

,

pulmonary eosinophilia

,

prostatic neoplasms

,

autoimmune diseases

,

,

growth and development

,

,

,

postherpetic neuralgia

,

healthy volunteers/patients

,

factor vii deficiency

,

,

hidradenitis suppurativa

,

chronic kidney failure

,

diabetes mellitus

,

diffuse scleroderma

,

,

systemic scleroderma

,

rheumatoid arthritis

,

chronic obstructive pulmonary disease

,

soft tissue infections

,

necrotizing fasciitis

,

fournier gangrene

,

,

raynaud disease

,

wounds and injuries

,

myasthenia gravis

,

cardiac surgical procedures

,

,

eosinophilic esophagitis

,

postpartum hemorrhage

,

acute kidney injury

,

sickle cell anemia

,

acute chest syndrome

,

vaso-occlusive crises

,

,

agammaglobulinemia

,

common variable immunodeficiency

,

graft vs host disease

,

hereditary angioedemas

,

afibrinogenemia

,

blood coagulation disorders

,

ischemic stroke

,

,

coronary artery disease

,

,

atherosclerosis

,

heart valve diseases

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

kidney transplantation

,

,

von willebrand diseases

,

hemostatic disorders

,

postoperative hemorrhage

,

dermatomyositis

,

atrial fibrillation

,

,

,

cardiovascular diseases

,

acute coronary syndrome

,

hemorrhagic stroke

,

peripheral arterial disease

,

central nervous system diseases

,

central nervous system infections

,

encephalomyelitis

,

,

meningoencephalitis

,

acquired immunodeficiency syndrome

,

,

factor xiii deficiency

,

thrombocytopenia

,

hematologic neoplasms

,

multiple myeloma

,

b-cell chronic lymphocytic leukemia

,

burkitt lymphoma

,

,

primary immunodeficiency diseases

,

,

hereditary angioedema types i and ii

,

alpha 1-antitrypsin deficiency

,

surgical blood loss

,

immunologic deficiency syndromes

,

thrombocytopenic purpura idiopathic

,

,

cardiovascular surgical procedures

,

tropical spastic paraparesis

,

thromboembolism

,

,

pneumococcal infections

,

,

streptococcal infections

,

bacterial pneumonia

,

bacterial meningitis

,

haemophilus influenzae

,

hereditary complement deficiency diseases

,

neisseriaceae infections

,

,

,

,

communicable diseases

,

ataxia telangiectasia

,

,

x-linked combined immunodeficiency diseases

,

cerebellar ataxia

primary myelofibrosis

,

healthy volunteers/patients

,

uterine cervical neoplasms

,

rectal neoplasms

,

cholangiocarcinoma

,

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

colorectal neoplasms

,

stomach neoplasms

,

,

,

ovarian neoplasms

,

triple negative breast neoplasms

,

large b-cell lymphoma diffuse

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

non-hodgkin lymphoma

,

ulcerative colitis

,

b-cell chronic lymphocytic leukemia

,

small cell lung carcinoma

,

,

neoplasm metastasis

,

b-cell lymphoma

,

,

,

lupus nephritis

,

ductal carcinoma breast

,

macular degeneration

,

,

renal cell carcinoma

,

transitional cell carcinoma

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

urinary bladder neoplasms

,

colonic neoplasms

,

,

head and neck neoplasms

,

,

,

mucinous adenocarcinoma

,

inflammatory breast neoplasms

,

paroxysmal hemoglobinuria

,

pancreatic neoplasms

,

,

,

,

neoplasms by site

,

breast diseases

,

urologic neoplasms

,

prostatic neoplasms

,

,

follicular lymphoma

,

lymphoid leukemia

,

systemic scleroderma

,

diffuse scleroderma

,

retinal vein occlusion

,

,

,

atypical hemolytic uremic syndrome

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

geographic atrophy

,

,

systemic lupus erythematosus

,

nephrotic syndrome

,

ovarian epithelial carcinoma

,

brain neoplasms

,

esophageal squamous cell carcinoma

,

esophageal neoplasms

,

castration-resistant prostatic neoplasms

,

retinal diseases

,

diabetic retinopathy

,

vision disorders

,

,

,

thyroid neoplasms

,

neuroendocrine carcinoma

,

papillary thyroid cancer

,

thyroid diseases

,

disease progression

,

,

endometrioid carcinoma

,

giant cell arteritis

,

type 2 diabetes mellitus

,

diabetes mellitus

,

membranous glomerulonephritis

,

multiple sclerosis

,

chronic progressive multiple sclerosis

,

ankylosing spondylitis

,

spondylarthritis

,

,

myeloid leukemia acute

,

myeloid leukemia

,

alzheimer disease

,

coronary disease

,

acute coronary syndrome

,

coronary artery disease

,

myocardial ischemia

,

,

relapsing-remitting multiple sclerosis

,

guillain-barre syndrome

,

autoimmune diseases of the nervous system

,

bcr-abl positive chronic myelogenous leukemia

,

circulating neoplastic cells

,

disability evaluation

,

cognition disorders

,

cytomegalovirus infections

,

,

,

hemolytic anemia autoimmune

,

,

focal segmental glomerulosclerosis

,

lipoid nephrosis

,

endometrial neoplasms

,

,

graft rejection

,

retinal neovascularization

,

human influenza

,

type 3 von willebrand disease

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

,

adenocarcinoma of lung

,

,

postmenopausal osteoporosis

Pegvorhyaluronidase alfa

non-small-cell lung carcinoma

,

cholangiocarcinoma

,

,

stomach neoplasms

,

pancreatic neoplasms

,

,

esophageal neoplasms

,

breast neoplasms

,

pancreatic ductal carcinoma

,

,

ductal carcinoma

,

thromboembolism

Polyglycolic acid

,

acquired immunodeficiency syndrome

,

,

cerebral toxoplasmosis

,

aids-related opportunistic infections

,

Globulin, immune

rectal neoplasms

,

ovarian epithelial carcinoma

,

b-cell lymphoma marginal zone

,

colonic neoplasms

,

intestinal neoplasms

,

hematologic diseases

,

myeloid leukemia

,

myelomonocytic leukemia juvenile

,

,

laryngeal diseases

,

,

liver neoplasms

,

alveolar soft part sarcoma

,

,

healthy volunteers/patients

,

,

,

,

esophageal neoplasms

,

,

,

clear cell adenocarcinoma

,

,

thymus neoplasms

,

,

central nervous system neoplasms

,

biphenotypic leukemia acute

,

burkitt lymphoma

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

rectal diseases

,

gastrointestinal diseases

,

digestive system diseases

,

colonic diseases

,

autism spectrum disorder

,

drug hypersensitivity

,

colorectal neoplasms

,

renal cell carcinoma

,

triple negative breast neoplasms

,

squamous cell carcinoma of head and neck

,

head and neck neoplasms

,

alzheimer disease

,

multiple myeloma

,

kidney neoplasms

,

,

multiple sclerosis

,

plasma cell neoplasms

,

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

prostatic neoplasms

,

squamous cell carcinoma

,

,

pancreatic neoplasms

,

ovarian neoplasms

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

castration-resistant prostatic neoplasms

,

intestinal diseases

,

mantle-cell lymphoma

,

,

,

myelomonocytic leukemia chronic

,

bone marrow diseases

,

sickle cell anemia

,

hypercholesterolemia

,

atherosclerosis

,

hepatocellular carcinoma

,

allergic rhinitis

,

,

,

invasive hydatidiform mole

,

stomach neoplasms

,

streptococcal infections

,

inflammatory bowel diseases

,

human influenza

,

,

waldenstrom macroglobulinemia

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

microscopic polyangiitis

,

margins of excision

,

hereditary sensory and autonomic neuropathies

,

,

cardiovascular diseases

,

type 2 diabetes mellitus

,

hyperlipoproteinemia type ii

,

,

patient compliance

,

pancreatic ductal carcinoma

,

membranous glomerulonephritis

,

,

small cell lung carcinoma

,

neuroendocrine tumors

,

mucocutaneous lymph node syndrome

,

endometrial neoplasms

,

bronchiolitis obliterans syndrome

,

,

anaplastic thyroid carcinoma

,

communicable diseases

,

bacterial infections

,

gram-positive bacterial infections

,

,

smoldering multiple myeloma

,

second primary neoplasms

,

,

japanese encephalitis

,

,

central serous chorioretinopathy

,

epstein-barr virus infections

,

oropharyngeal neoplasms

,

squamous cell neoplasms

,

hodgkin disease

,

neuroendocrine carcinoma

,

type 1 diabetes mellitus

,

,

neurofibrosarcoma

,

fallopian tube neoplasms

,

coronavirus infections

,

,

,

eosinophilic esophagitis

,

,

female infertility

,

solar urticaria

,

angioid streaks

,

pseudoxanthoma elasticum

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

diffuse scleroderma

,

hemolytic anemia autoimmune

,

,

non-small-cell lung carcinoma

,

,

,

iga glomerulonephritis

,

,

meningococcal meningitis

,

,

glomerulonephritis

,

non-hodgkin lymphoma

,

cryopyrin-associated periodic syndromes

,

,

b-cell chronic lymphocytic leukemia

,

,

,

,

follicular lymphoma

,

urologic diseases

,

brain neoplasms

,

lymphoid leukemia

,

paroxysmal hemoglobinuria

,

retinopathy of prematurity

,

,

aplastic anemia

,

,

,

,

autoimmune diseases

,

juvenile arthritis

,

haemophilus infections

,

degenerative myopia

,

ankylosing spondylitis

,

polymyalgia rheumatica

,

graft vs host disease

,

psychology rejection

,

organ transplantation

,

graft rejection

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

gouty arthritis

,

osteitis deformans

,

,

allergic rhinitis seasonal

,

sjogren's syndrome

,

,

peanut hypersensitivity

,

hematologic neoplasms

,

,

neovascular glaucoma

,

giant cell arteritis

,

,

,

neoplasms by site

,

thrombocytopenic purpura idiopathic

,

chronic obstructive pulmonary disease

,

,

,

,

familial mediterranean fever

,

,

,

axial spondyloarthritis

,

,

,

,

,

,

,

thrombotic microangiopathies

,

atypical hemolytic uremic syndrome

,

choroid diseases

,

uveal neoplasms

,

,

,

pulmonary eosinophilia

,

,

,

alpha 1-antitrypsin deficiency

,

lupus nephritis

,

immune system diseases

,

male urogenital diseases

,

,

female urogenital diseases

,

female urogenital diseases and pregnancy complications

,

urogenital diseases

,

lymphoproliferative disorders

,

neoplasms by histologic type

,

,

breast neoplasms

,

macular degeneration

,

,

,

,

,

choroidal neovascularization

,

kidney transplantation

,

vision disorders

,

meningococcal infections

,

retinal vein occlusion

,

neoplasm metastasis

,

rheumatoid arthritis

,

chronic urticaria

,

psoriatic arthritis

,

diabetic retinopathy

,

kidney diseases

,

,

liver transplantation

,

chronic renal insufficiency

,

relapsing-remitting multiple sclerosis

,

diabetes mellitus

,

spondylarthritis

,

retinal diseases

,

,

wet macular degeneration

,

geographic atrophy

,

pathologic neovascularization

,

,

polypoidal choroidal vasculopathy

,

hypersensitivity

,

renal insufficiency

,

chronic kidney failure

,

,

retinal neovascularization

,

retinal detachment

,

diabetes complications

,

thrombocytopenia

,

migraine disorders

,

,

hidradenitis suppurativa

,

,

,

food hypersensitivity

,

,

renal replacement therapy

,

drug-related side effects and adverse reactions

,

,

tick-borne encephalitis

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

,

,

liver cirrhosis

,

,

,

reperfusion injury

,

delayed graft function

,

,

,

,

hematopoietic stem cell transplantation

,

chronic progressive multiple sclerosis

hematologic neoplasms

,

fallopian tube neoplasms

,

ovarian epithelial carcinoma

,

myeloid leukemia acute

,

myelodysplastic syndromes

,

hodgkin disease

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

hematopoietic stem cell transplantation

,

plasma cell neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

stomach neoplasms

,

,

breast neoplasms

,

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

type 1 diabetes mellitus

,

graft vs host disease

,

stem cell transplantation

,

pulmonary alveolar proteinosis

,

,

alpha 1-antitrypsin deficiency

,

multiple myeloma

,

,

,

venous thrombosis

,

aplastic anemia

,

pulmonary embolism

,

,

,

,

atrial fibrillation

,

thromboembolism

,

non-hodgkin lymphoma

,

prostatic neoplasms

,

,

autologous transplantation

,

,

lymphoproliferative disorders

,

paraproteinemias

prostatic neoplasms

,

small cell carcinoma

,

neuroendocrine tumors

,

pancreatic ductal carcinoma

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