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BioLineRx
BioLineRx
BioLineRx (Hebrew: ביוליין אר אקס), or BioLine, is a publicly traded drug development company. Headquartered in Israel, its shares are traded on the NASDAQ Capital Market and on the Tel Aviv Stock Exchange.
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Aphexda
Motixafortide
2023-09-08
Hematopoietic stem cell mobilization
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Motixafortide
sickle cell anemia
,
hematopoietic stem cell mobilization
,
healthy volunteers/patients
,
myeloid leukemia acute
,
leukemia
,
myeloid leukemia
,
myelodysplastic syndromes
,
esophageal neoplasms
,
adenocarcinoma
,
anemia
,
aplastic anemia
,
preleukemia
,
syndrome
,
pancreatic neoplasms
,
hematologic neoplasms
,
myeloproliferative disorders
,
non-hodgkin lymphoma
,
lymphoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
bcr-abl positive chronic myelogenous leukemia
,
hodgkin disease
,
multiple myeloma
,
plasma cell neoplasms
Docusate
primary myelofibrosis
,
lung neoplasms
,
small cell lung carcinoma
Tiragolumab
colorectal neoplasms
,
breast neoplasms
,
triple negative breast neoplasms
,
adenocarcinoma
,
squamous cell carcinoma of head and neck
,
small cell carcinoma
,
uterine cervical neoplasms
,
urologic neoplasms
,
urinary bladder neoplasms
,
transitional cell carcinoma
,
pancreatic neoplasms
,
stomach neoplasms
,
rectal neoplasms
,
melanoma
,
non-hodgkin lymphoma
,
lymphoma
,
follicular lymphoma
,
b-cell lymphoma
,
head and neck neoplasms
,
renal cell carcinoma
,
recurrence
,
microsatellite instability
,
carcinoma
,
non-small-cell lung carcinoma
,
lung neoplasms
,
squamous cell carcinoma
,
neoplasms
,
small cell lung carcinoma
,
liver neoplasms
,
esophageal neoplasms
,
hepatocellular carcinoma
,
esophageal squamous cell carcinoma
Lenograstim
lymphoma
,
hodgkin disease
,
neoplasms
,
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
neutropenia
,
chemotherapy-induced febrile neutropenia
,
healthy volunteers/patients
Maxacalcitol
edema
,
retinitis pigmentosa
,
retinitis
,
macular degeneration
,
macular edema
,
vascular diseases
,
polypoidal choroidal vasculopathy
,
choroidal neovascularization
,
retinal vein occlusion
,
wet macular degeneration
,
multiple sclerosis
,
inflammation
,
sclerosis
,
respiratory distress syndrome
,
acute lung injury
,
newborn respiratory distress syndrome
,
syndrome
Vorhyaluronidase alfa
neoplasms
,
neoplasms by site
,
urologic neoplasms
,
transitional cell carcinoma
,
multiple myeloma
,
plasma cell neoplasms
,
melanoma
,
carcinoma
,
renal cell carcinoma
Molgramostim
leukemia
,
lymphoma
,
prostatic neoplasms
,
melanoma
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
myeloproliferative disorders
,
myeloid leukemia
,
preleukemia
,
non-hodgkin lymphoma
,
biphenotypic leukemia acute
,
syndrome
,
multiple myeloma
,
hematologic diseases
,
anemia
,
hodgkin disease
,
aplastic anemia
,
renal cell carcinoma
,
carcinoma
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
breast neoplasms
,
b-cell lymphoma
,
hepatocellular carcinoma
,
liver neoplasms
,
ovarian neoplasms
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
urinary bladder neoplasms
Raclopride
healthy volunteers/patients
Alunacedase alfa
hypoxia
,
healthy volunteers/patients
,
hypertension
,
pulmonary hypertension
,
pulmonary arterial hypertension
,
wounds and injuries
,
acute lung injury
,
lung injury
Aspartame
medical sociology
,
renal insufficiency
,
thrombosis
,
venous thrombosis
,
neoplasms
,
obstructive sleep apnea
,
sleep apnea syndromes
,
apnea
,
chronic renal insufficiency
,
kidney diseases
,
carcinoma
,
salivary gland neoplasms
,
heart failure
,
non-hodgkin lymphoma
,
lymphoma
,
infections
,
human experimentation
,
hypersensitivity
,
venous thromboembolism
,
thromboembolism
,
b-cell lymphoma
,
contraception
,
hypertension
,
pulmonary hypertension
,
pulmonary arterial hypertension
,
stroke
,
respiratory insufficiency
,
communicable diseases
,
rheumatic diseases
,
collagen diseases
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
macular edema
,
retinal vein occlusion
,
wounds and injuries
,
wound healing
,
edema
,
postmenopause
,
endometriosis
,
chronic pain
,
interstitial cystitis
,
pelvic pain
,
syndrome
Nepidermin
squamous cell carcinoma of head and neck
,
primary myelofibrosis
,
healthy volunteers/patients
,
uterine cervical neoplasms
,
cholangiocarcinoma
,
folliculitis
,
glioma
,
central nervous system neoplasms
,
nervous system neoplasms
,
colorectal neoplasms
,
lymphoma
,
carcinoma
,
stomach neoplasms
,
b-cell lymphoma
,
triple negative breast neoplasms
,
large b-cell lymphoma diffuse
,
neoplasms
,
ovarian neoplasms
,
leukemia
,
hepatocellular carcinoma
,
liver neoplasms
,
recurrence
,
melanoma
,
non-hodgkin lymphoma
,
ulcerative colitis
,
colitis
,
ulcer
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
small cell lung carcinoma
,
ovarian epithelial carcinoma
,
neoplasm metastasis
,
hemophilia a
,
macular edema
,
edema
,
syndrome
,
peritoneal neoplasms
,
lupus nephritis
,
nephritis
,
sclerosis
,
ductal carcinoma breast
,
macular degeneration
,
urinary bladder neoplasms
,
renal cell carcinoma
,
fallopian tube neoplasms
,
glioblastoma
,
head and neck neoplasms
,
asthma
,
mucinous adenocarcinoma
,
inflammatory breast neoplasms
,
paroxysmal hemoglobinuria
,
hemoglobinuria
,
pancreatic neoplasms
,
hemolysis
,
squamous cell carcinoma
,
urologic neoplasms
,
prostatic neoplasms
,
transitional cell carcinoma
,
colonic neoplasms
,
multiple sclerosis
,
nasal polyps
,
polyps
,
rhinosinusitis
,
wet macular degeneration
,
follicular lymphoma
,
systemic scleroderma
,
diffuse scleroderma
,
retinal vein occlusion
,
crohn disease
,
schizophrenia
,
hemolytic-uremic syndrome
,
atypical hemolytic uremic syndrome
,
azotemia
,
fibrosis
,
idiopathic pulmonary fibrosis
,
pulmonary fibrosis
,
autistic disorder
,
autism spectrum disorder
,
pervasive child development disorders
,
geographic atrophy
,
atrophy
,
systemic lupus erythematosus
,
nephrotic syndrome
,
nephrosis
,
lipoid nephrosis
,
esophageal squamous cell carcinoma
,
esophageal neoplasms
,
castration-resistant prostatic neoplasms
,
retinal diseases
,
diabetic retinopathy
,
thyroid neoplasms
,
neuroendocrine carcinoma
,
papillary thyroid cancer
,
thyroid diseases
,
disease progression
,
endometrioid carcinoma
,
arteritis
,
giant cell arteritis
,
polymyalgia rheumatica
,
type 2 diabetes mellitus
,
diabetes mellitus
,
kidney diseases
,
membranous glomerulonephritis
,
chronic progressive multiple sclerosis
,
sinusitis
,
ankylosing spondylitis
,
spondylarthritis
,
spondylitis
,
residual neoplasm
,
myeloid leukemia acute
,
myeloid leukemia
,
alzheimer disease
,
coronary disease
,
acute coronary syndrome
,
coronary artery disease
,
myocardial ischemia
,
heart diseases
,
relapsing-remitting multiple sclerosis
,
guillain-barre syndrome
,
autoimmune diseases of the nervous system
,
hashimoto disease
,
encephalitis
,
partial epilepsies
,
bcr-abl positive chronic myelogenous leukemia
,
disability evaluation
,
cognition disorders
,
cytomegalovirus infections
,
anemia
,
hemolytic anemia autoimmune
,
hemolytic anemia
,
mantle-cell lymphoma
,
skin diseases
,
neoplasms by site
,
breast diseases
,
endometrial neoplasms
,
covid-19
,
graft rejection
,
choroidal neovascularization
,
myopia
,
retinal neovascularization
,
pathologic neovascularization
,
human influenza
,
breast neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
adenocarcinoma
,
adenocarcinoma of lung
,
osteoporosis
,
postmenopausal osteoporosis
Pegvorhyaluronidase alfa
non-small-cell lung carcinoma
,
neoplasms
,
cholangiocarcinoma
,
lung neoplasms
,
stomach neoplasms
,
pancreatic neoplasms
,
esophageal neoplasms
,
breast neoplasms
,
adenocarcinoma
,
pancreatic ductal carcinoma
,
ductal carcinoma
Polyglycolic acid
healthy volunteers/patients
Retinol
renal cell carcinoma
,
carcinoma
,
recurrence
,
colonic neoplasms
,
rectal neoplasms
,
gastrointestinal neoplasms
,
digestive system neoplasms
,
gastrointestinal stromal tumors
,
colorectal neoplasms
,
pancreatic neoplasms
,
adenocarcinoma
,
myeloid leukemia chronic-phase
,
hematologic diseases
,
stomach neoplasms
,
brain stem neoplasms
,
philadelphia chromosome
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
psoriatic arthritis
,
arthritis
,
osteoporosis
,
bcr-abl positive chronic myelogenous leukemia
,
neoplasms
,
leukemia
,
myeloid leukemia
,
breast neoplasms
,
prostatic neoplasms
,
multiple sclerosis
,
sclerosis
,
bone diseases
,
osteitis deformans
,
hypertension
,
hypocalcemia
,
non-small-cell lung carcinoma
,
lung neoplasms
,
bone neoplasms
,
neoplasm metastasis
,
bone marrow diseases
,
vitamin d deficiency
,
angina pectoris
,
microvascular angina
,
beta-thalassemia
,
thalassemia
Mk3475
thoracic neoplasms
,
glandular and epithelial neoplasms
,
lip neoplasms
,
eye neoplasms
,
myelodysplastic syndromes
,
pharmacokinetics
,
soft tissue neoplasms
,
digestive system neoplasms
,
lung diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
endocrine gland neoplasms
,
breast diseases
,
bronchial neoplasms
,
intraductal carcinoma noninfiltrating
,
myoepithelioma
,
oligodendroglioma
,
death
,
pancreatic neoplasms
,
neoplasm metastasis
,
sarcoma
,
b-cell lymphoma
,
brain neoplasms
,
large b-cell lymphoma diffuse
,
castration-resistant prostatic neoplasms
,
non-hodgkin lymphoma
,
t-cell lymphoma
,
leukemia
,
neuroendocrine tumors
,
cholangiocarcinoma
,
follicular lymphoma
,
myeloid leukemia acute
,
neuroendocrine carcinoma
,
t-cell lymphoma peripheral
,
kidney neoplasms
,
thyroid neoplasms
,
pancreatic ductal carcinoma
,
uterine neoplasms
,
uveal neoplasms
,
myeloid leukemia
,
invasive hydatidiform mole
,
lymphoid leukemia
,
glioma
,
female genital neoplasms
,
small cell carcinoma
,
urethral neoplasms
,
colonic neoplasms
,
vulvar neoplasms
,
b-cell lymphoma marginal zone
,
anus neoplasms
,
thyroid diseases
,
cutaneous malignant melanoma
,
thymoma
,
microsatellite repeats
,
gastrointestinal neoplasms
,
mouth neoplasms
,
oropharyngeal neoplasms
,
laryngeal neoplasms
,
ureteral neoplasms
,
salivary gland neoplasms
,
endometrioid carcinoma
,
serous cystadenocarcinoma
,
mantle-cell lymphoma
,
waldenstrom macroglobulinemia
,
penile neoplasms
,
b-cell chronic lymphocytic leukemia
,
gliosarcoma
,
carcinosarcoma
,
mullerian mixed tumor
,
astrocytoma
,
thymus neoplasms
,
rectal neoplasms
,
hypopharyngeal neoplasms
,
male genital neoplasms
,
bile duct neoplasms
,
respiratory tract infections
,
papillomavirus infections
,
papilloma
,
adenoid cystic carcinoma
,
meningioma
,
male breast neoplasms
,
leiomyosarcoma
,
malignant fibrous histiocytoma
,
epstein-barr virus infections
,
adenocarcinoma of lung
,
oncogenes
,
neurofibrosarcoma
,
nerve sheath neoplasms
,
uveal melanoma
,
mycoses
,
sezary syndrome
,
mycosis fungoides
,
t-cell lymphoma cutaneous
,
syndrome
,
pelvic neoplasms
,
hemangiosarcoma
,
osteosarcoma
,
germ cell and embryonal neoplasms
,
neoplasms by histologic type
,
adenoviridae infections
,
basal cell carcinoma
,
anaplastic thyroid carcinoma
,
reactive arthritis
,
gallbladder neoplasms
,
clear cell adenocarcinoma
,
adenosquamous carcinoma
,
gestational trophoblastic disease
,
alveolar soft part sarcoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
biphenotypic leukemia acute
,
local neoplasm recurrence
,
sclerosis
,
chordoma
,
meningeal carcinomatosis
,
papillomaviridae
,
second primary neoplasms
,
immunoblastic lymphadenopathy
,
enteropathy-associated t-cell lymphoma
,
intestinal diseases
,
panniculitis
,
carcinoma in situ
,
cervical intraepithelial neoplasia
,
uterine cervical dysplasia
,
squamous intraepithelial lesions of the cervix
,
central nervous system diseases
,
extranodal nk-t-cell lymphoma
,
liposarcoma
,
virus diseases
,
viremia
,
unknown primary neoplasms
,
synovial sarcoma
,
point mutation
,
oral leukoplakia
,
leukoplakia
,
lymphoproliferative disorders
,
endoscopy
,
colonic diseases
,
histiocytic sarcoma
,
follicular dendritic cell sarcoma
,
interdigitating dendritic cell sarcoma
,
environmental biomarkers
,
circulating neoplastic cells
,
inflammatory breast neoplasms
,
meningeal neoplasms
,
intestinal neoplasms
,
central nervous system neoplasms
,
nervous system neoplasms
,
nervous system diseases
,
nerve tissue neoplasms
,
primitive neuroectodermal tumors
,
neuroepithelial neoplasms
,
neuroectodermal tumors
,
adrenocortical carcinoma
,
carcinoid tumor
,
mediastinal neoplasms
,
testicular neoplasms
,
gastrointestinal stromal tumors
,
hairy cell leukemia
,
burkitt lymphoma
,
laryngeal diseases
,
vaginal neoplasms
,
acinar cell carcinoma
,
adenomyoepithelioma
,
hereditary breast and ovarian cancer syndrome
,
maxillary sinus neoplasms
,
basal cell neoplasms
,
urogenital neoplasms
,
male urogenital diseases
,
urogenital diseases
,
neoplasms
,
lung neoplasms
,
breast neoplasms
,
colorectal neoplasms
,
triple negative breast neoplasms
,
lymphoma
,
renal cell carcinoma
,
ovarian neoplasms
,
adenocarcinoma
,
recurrence
,
head and neck neoplasms
,
urinary bladder neoplasms
,
prostatic neoplasms
,
stomach neoplasms
,
esophageal neoplasms
,
liver neoplasms
,
hepatocellular carcinoma
,
endometrial neoplasms
,
uterine cervical neoplasms
,
ovarian epithelial carcinoma
,
small cell lung carcinoma
,
transitional cell carcinoma
,
hodgkin disease
,
fallopian tube neoplasms
,
urologic neoplasms
,
multiple myeloma
,
glioblastoma
,
squamous cell neoplasms
,
mesothelioma
,
plasma cell neoplasms
,
skin neoplasms
,
esophageal squamous cell carcinoma
,
biliary tract neoplasms
,
malignant mesothelioma
,
peritoneal neoplasms
,
microsatellite instability
,
merkel cell carcinoma
,
non-muscle invasive bladder neoplasms
,
hematologic neoplasms
,
hypersensitivity
,
nasopharyngeal neoplasms
,
nasopharyngeal carcinoma
,
disease progression
,
muscle neoplasms
,
carcinoma
,
non-small-cell lung carcinoma
,
melanoma
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
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