Tiragolumab
Tiragolumab is an antibody pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
65 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | 4 | 7 | 2 | — | — | 9 |
| Non-small-cell lung carcinoma | D002289 | — | — | 1 | 4 | 4 | — | — | 7 |
| Lung neoplasms | D008175 | — | C34.90 | — | 2 | 5 | — | — | 6 |
| Squamous cell carcinoma | D002294 | — | — | 1 | 3 | 1 | — | — | 4 |
| Neoplasms | D009369 | — | C80 | — | 3 | 1 | — | — | 4 |
| Small cell lung carcinoma | D055752 | — | — | — | 1 | 2 | — | — | 3 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 2 | 2 | 1 | — | — | 3 |
| Esophageal neoplasms | D004938 | — | C15 | 1 | 1 | 1 | — | — | 2 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 1 | 1 | 1 | — | — | 2 |
| Esophageal squamous cell carcinoma | D000077277 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 2 | — | — | — | 3 |
| Triple negative breast neoplasms | D064726 | — | — | 1 | 2 | — | — | — | 3 |
| Adenocarcinoma | D000230 | — | — | 2 | 3 | — | — | — | 3 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 1 | 2 | — | — | — | 2 |
| Small cell carcinoma | D018288 | — | — | — | 1 | — | — | — | 1 |
| Uterine cervical neoplasms | D002583 | — | — | — | 1 | — | — | — | 1 |
| Urologic neoplasms | D014571 | — | C64-C68 | 1 | 1 | — | — | — | 1 |
| Urinary bladder neoplasms | D001749 | — | C67 | 1 | 1 | — | — | — | 1 |
| Transitional cell carcinoma | D002295 | — | — | 1 | 1 | — | — | — | 1 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Tiragolumab |
| INN | tiragolumab |
| Description | Tiragolumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | >8JEQ:A|antibody heavy chain
EVQLQQSGPGLVKPSQTLSLTCAISGDSVSSNSAAWNWIRQSPSRGLEWLGKTYYRFKWYSDYAVSVKGRITINPDTSKN
QFSLQLNSVTPEDTAVFYCTRESTTYDLLAGPFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFP
EPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCHHHHHH
>8JEQ:B|antibody light chain
DIVMTQSPDSLAVSLGERATINCKSSQTVLYSSNNKKYLAWYQQKPGQPPNLLIYWASTRESGVPDRFSGSGSGTDFTLT
ISSLQAEDVAVYYCQQYYSTPFTFGPGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNAL
QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC |
Identifiers
| PDB | 8JEO, 8JEQ |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4298050 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 6XG22YQM2Z (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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510 adverse events reported
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