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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Vyvgart	Efgartigimod alfa	2021-12-17		Myasthenia gravis , Extravasation of diagnostic and therapeutic materials
Vyvgart hytrulo	Efgartigimod alfa, Hyaluronidase	2023-06-20		Extravasation of diagnostic and therapeutic materials , Breast neoplasms , Gastrointestinal neoplasms , Multiple myeloma , Non-small-cell lung carcinoma , Hepatocellular carcinoma , Urinary bladder neoplasms , Melanoma , Small cell lung carcinoma , Alveolar soft part sarcoma , Multiple sclerosis

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

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Status:

All

Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

hypersensitivity

hemolytic anemia

,

hemolytic anemia congenital nonspherocytic

,

inborn errors pyruvate metabolism

Vorhyaluronidase alfa

Sodium chloride

bacterial infections

,

gram-negative bacterial infections

,

hypertriglyceridemia

,

allergic rhinitis

,

,

,

migraine disorders

,

systemic lupus erythematosus

,

cutaneous lupus erythematosus

,

staphylococcal infections

,

,

,

respiratory syncytial viruses

,

sickle cell anemia

,

type 2 diabetes mellitus

,

diabetes mellitus

,

streptococcal infections

,

alzheimer disease

,

respiratory tract infections

,

borrelia infections

,

,

meningococcal infections

,

cerebral amyloid angiopathy

,

,

familial cerebral amyloid angiopathy

,

,

pulmonary sarcoidosis

,

serogroup b neisseria meningitidis

,

esophageal neoplasms

,

ventilator-associated pneumonia

,

,

,

healthy volunteers/patients

,

,

pneumococcal infections

,

,

clostridium infections

,

,

clostridioides difficile

,

meningococcal meningitis

,

human influenza

,

essential hypertension

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

community-acquired infections

,

bacterial pneumonia

,

,

headache disorders

,

,

renal cell carcinoma

,

,

gastrointestinal stromal tumors

,

,

alopecia areata

,

,

,

,

postoperative pain

,

,

pneumococcal pneumonia

,

streptococcus pneumoniae

,

,

hyperlipidemias

,

,

cardiovascular diseases

,

health risk behaviors

,

vascular stiffness

hepatic insufficiency

,

renal insufficiency

,

castration-resistant prostatic neoplasms

,

,

,

,

,

unknown primary neoplasms

,

immunomodulation

,

gram-positive bacterial infections

,

t-cell lymphoma peripheral

,

,

merkel cell carcinoma

,

mycosis fungoides

,

clear cell sarcoma

,

myelodysplastic syndromes

,

,

,

pulmonary sarcoidosis

,

lyme neuroborreliosis

,

hypertriglyceridemia

,

,

granuloma annulare

,

mycobacterium avium complex

,

thoracic neoplasms

,

pelvic neoplasms

,

,

,

brain neoplasms

,

stomach neoplasms

,

,

triple negative breast neoplasms

,

multiple myeloma

,

head and neck neoplasms

,

urinary bladder neoplasms

,

ovarian neoplasms

,

thyroid neoplasms

,

plasma cell neoplasms

,

,

small cell lung carcinoma

,

ovarian epithelial carcinoma

,

esophageal neoplasms

,

borrelia infections

,

endometrial neoplasms

,

thyroid diseases

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

uveal neoplasms

,

respiratory syncytial viruses

,

,

,

transitional cell carcinoma

,

kidney diseases

,

small cell carcinoma

,

adenocarcinoma of lung

,

large-cell lymphoma anaplastic

,

,

,

pheochromocytoma

,

,

healthcare-associated pneumonia

,

systemic lupus erythematosus

,

alopecia areata

,

,

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

oligodendroglioma

,

,

hemangioblastoma

,

urogenital neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

germ cell and embryonal neoplasms

,

carcinoid tumor

,

urethral neoplasms

,

ureteral neoplasms

,

alveolar soft part sarcoma

,

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

cholangiocarcinoma

,

gene rearrangement

,

lobular carcinoma

,

plasma cell leukemia

,

medulloblastoma

,

,

rhabdomyosarcoma

,

diffuse intrinsic pontine glioma

,

intraductal carcinoma noninfiltrating

,

b-cell lymphoma

,

cutaneous lupus erythematosus

,

keratoconjunctivitis

,

,

respiratory tract infections

,

,

,

,

hidradenitis suppurativa

,

,

meningococcal infections

,

neoadjuvant therapy

,

diabetes mellitus

,

type 1 diabetes mellitus

,

,

multidrug-resistant tuberculosis

,

von hippel-lindau disease

,

,

,

neurodermatitis

,

,

urologic neoplasms

,

urologic diseases

,

neoplasms by site

,

glandular and epithelial neoplasms

,

,

,

benign fibrous histiocytoma

,

,

malignant fibrous histiocytoma

,

myeloid leukemia accelerated phase

,

,

malignant mesothelioma

,

,

urinary bladder diseases

,

adrenal cortex neoplasms

,

adrenocortical carcinoma

,

second primary neoplasms

,

pulmonary tuberculosis

,

hematologic neoplasms

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

mouth neoplasms

,

,

penile neoplasms

,

plexiform neurofibroma

,

,

testicular neoplasms

,

solitary fibrous tumors

,

,

hemangiopericytoma

,

male urogenital diseases

,

urogenital diseases

,

,

adenoid cystic carcinoma

,

,

hemangiosarcoma

,

systemic scleroderma

,

diffuse scleroderma

,

,

,

post-acute covid-19 syndrome

,

,

colorectal neoplasms

,

atopic dermatitis

,

,

,

,

,

kidney neoplasms

,

prostatic neoplasms

,

squamous cell carcinoma

,

hepatocellular carcinoma

,

liver neoplasms

,

pancreatic neoplasms

,

neoplasm metastasis

,

,

psoriatic arthritis

,

squamous cell neoplasms

,

squamous cell carcinoma of head and neck

,

,

male breast neoplasms

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

myeloid leukemia chronic-phase

,

juvenile arthritis

,

,

,

bacterial pneumonia

,

,

mycobacterium avium-intracellulare infection

,

immune system diseases

,

inborn genetic diseases

,

genetic skin diseases

,

eczematous skin diseases

,

hypersensitivity

,

immediate hypersensitivity

,

islet cell carcinoma

,

ankylosing spondylitis

,

bacterial infections

,

pancreatic ductal carcinoma

,

,

,

febrile neutropenia

,

,

mycobacterium infections

,

adenosquamous carcinoma

,

large cell carcinoma

,

nervous system diseases

,

optic nerve diseases

,

disease progression

,

cardiovascular diseases

,

immunologic deficiency syndromes

,

breast neoplasms

,

healthy volunteers/patients

,

,

renal cell carcinoma

,

non-small-cell lung carcinoma

,

,

,

rheumatoid arthritis

,

,

,

,

,

acquired immunodeficiency syndrome

,

communicable diseases

,

bcr-abl positive chronic myelogenous leukemia

,

,

myeloid leukemia

,

neuroendocrine tumors

,

gastrointestinal stromal tumors

,

ulcerative colitis

,

,

,

non-hodgkin lymphoma

,

kidney transplantation

,

philadelphia chromosome

,

islet cell adenoma

,

intraabdominal infections

,

mantle-cell lymphoma

,

,

spondylarthritis

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

,

,

,

,

,

ventilator-associated pneumonia

,

chronic hepatitis c

,

,

axial spondyloarthritis

,

,

premature birth

,

bacterial vaginosis

,

vaginal diseases

,

,

infectious skin diseases

,

soft tissue infections

,

,

,

community-acquired infections

,

staphylococcal infections

,

,

hypercholesterolemia

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

bacterial skin diseases

,

,

asymptomatic infections

,

,

,

respiratory tract diseases

,

myeloid leukemia acute

,

myeloid leukemia

,

myelodysplastic syndromes

,

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

kidney transplantation

post-traumatic stress disorders

,

traumatic stress disorders

pharmacokinetics

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

positron-emission tomography

,

,

alzheimer disease

,

diagnostic imaging

,

small cell lung carcinoma

,

medical sociology

,

renal insufficiency

,

drug interactions

,

electrocardiography

,

therapeutic equivalency

,

pharmacological phenomena

,

,

,

stomach neoplasms

,

hematologic neoplasms

,

respiratory aspiration

,

,

biological availability

,

,

non-small-cell lung carcinoma

,

,

postcoital contraception

,

ovulation inhibition

,

atrial fibrillation

,

breast neoplasms

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

cardiomyopathies

,

cardiovascular diseases

,

parkinson disease

,

,

,

,

hormonal contraception

,

unplanned pregnancy

,

b-cell lymphoma

,

ovarian neoplasms

,

,

skin abnormalities

,

myocardial infarction

,

,

,

acquired immunodeficiency syndrome

,

magnetic resonance angiography

,

,

,

pulmonary hypertension

,

left ventricular dysfunction

,

ventricular dysfunction

,

,

,

,

prostatic hyperplasia

,

,

angina pectoris

,

,

ischemic stroke

,

,

,

cerebral infarction

,

urologic neoplasms

,

head and neck neoplasms

,

thromboembolism

,

venous thromboembolism

,

,

,

surgical blood loss

,

,

venous thrombosis

,

non-hodgkin lymphoma

,

,

chronic renal insufficiency

,

,

prostatic neoplasms

,

hyperphosphatemia

,

kidney diseases

,

postoperative hemorrhage

,

pulmonary embolism

,

,

,

,

,

vascular diseases

,

peripheral arterial disease

,

peripheral vascular diseases

,

bacterial infections

,

esophageal neoplasms

,

,

,

intraabdominal infections

,

,

chronic progressive multiple sclerosis

,

blood coagulation disorders

,

hemostatic disorders

,

hormone replacement therapy

,

hyperlipidemias

,

hyperlipoproteinemias

,

choroidal neovascularization

,

,

degenerative myopia

,

pathologic neovascularization

,

,

aspiration pneumonia

,

,

,

pelvic infection

,

pelvic inflammatory disease

,

,

metabolic bone diseases

,

,

premenstrual dysphoric disorder

,

diabetic nephropathies

,

,

follicular lymphoma

,

magnetic resonance imaging

,

brain neoplasms

,

,

memory disorders

,

,

,

depressive disorder

,

spinal cord injuries

,

hypersensitivity

,

abdominal abscess

,

erectile dysfunction

,

,

,

,

,

,

healthy volunteers/patients

,

,

,

communicable diseases

,

multiple sclerosis

,

,

,

,

diabetes mellitus

,

,

type 2 diabetes mellitus

,

relapsing-remitting multiple sclerosis

,

essential hypertension

,

,

atopic dermatitis

,

,

renal cell carcinoma

,

,

acute coronary syndrome

,

coronary artery disease

,

,

tension-type headache

,

,

chronic bronchitis

,

,

,

,

,

physiological sexual dysfunction

,

colorectal neoplasms

,

urinary tract infections

,

,

coronary disease

,

myocardial ischemia

,

respiratory tract infections

,

,

macular degeneration

,

energy metabolism

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

,

gene expression

,

cell proliferation

,

,

neoplasm metastasis

,

central nervous system neoplasms

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