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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Vyvgart	Efgartigimod alfa	2021-12-17		Myasthenia gravis , Extravasation of diagnostic and therapeutic materials
Vyvgart hytrulo	Hyaluronidase, Efgartigimod alfa	2023-06-20		Extravasation of diagnostic and therapeutic materials , Breast neoplasms , Gastrointestinal neoplasms , Multiple myeloma , Non-small-cell lung carcinoma , Hepatocellular carcinoma , Urinary bladder neoplasms , Melanoma , Small cell lung carcinoma , Alveolar soft part sarcoma , Multiple sclerosis , Lymphoma , Kidney neoplasms , Squamous cell carcinoma

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

,

Efgartigimod alfa

healthy volunteers/patients

,

therapeutic equivalency

,

renal insufficiency

,

postural orthostatic tachycardia syndrome

,

,

neuromyelitis optica

,

systemic scleroderma

,

diffuse scleroderma

,

kidney diseases

,

membranous glomerulonephritis

,

lupus nephritis

,

,

,

stiff-person syndrome

,

,

,

,

thrombotic thrombocytopenic purpura

,

thrombocytopenic purpura

,

,

epidermolysis bullosa

,

epidermolysis bullosa dystrophica

,

epidermolysis bullosa acquisita

,

immunoglobulin g4-related disease

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

,

,

,

sjogren's syndrome

,

bullous pemphigoid

,

guillain-barre syndrome

,

,

dermatomyositis

,

muscular diseases

,

,

graves ophthalmopathy

,

,

thyroid diseases

,

myasthenia gravis

,

muscle weakness

,

polyneuropathies

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

autoimmune diseases

,

neuromuscular diseases

Hyaluronidase (human recombinant)

healthy volunteers/patients

,

,

bullous pemphigoid

,

,

dermatomyositis

,

muscular diseases

,

,

,

chronic hepatitis c

,

,

,

drug-related side effects and adverse reactions

,

small cell lung carcinoma

,

pancreatic neoplasms

,

,

healthy volunteers/patients

,

kidney neoplasms

,

mantle-cell lymphoma

,

breast neoplasms

,

,

colorectal neoplasms

,

,

colonic neoplasms

,

rectal neoplasms

,

esophageal neoplasms

,

prostatic neoplasms

,

hepatocellular carcinoma

,

liver neoplasms

,

myeloid leukemia acute

,

myeloid leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

philadelphia chromosome

,

mucinous adenocarcinoma

,

cystadenocarcinoma

,

gastrointestinal stromal tumors

,

,

juvenile arthritis

,

,

,

head and neck neoplasms

,

diabetes mellitus

,

type 1 diabetes mellitus

,

waldenstrom macroglobulinemia

,

adenocarcinoma of lung

,

myelodysplastic syndromes

,

,

,

,

,

non-small-cell lung carcinoma

,

,

,

renal cell carcinoma

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

thrombocytopenic purpura

,

,

hematologic neoplasms

,

,

stomach neoplasms

,

,

thyroid neoplasms

,

thyroid diseases

,

,

multiple myeloma

,

plasma cell neoplasms

,

neoplasm metastasis

,

,

,

rheumatoid arthritis

,

,

postmenopausal osteoporosis

nasopharyngeal carcinoma

,

,

myeloid leukemia acute

,

myeloid leukemia

,

myelodysplastic syndromes

,

,

,

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

Globulin, immune

follicular lymphoma

,

myeloid leukemia acute

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

b-cell lymphoma marginal zone

,

mantle-cell lymphoma

,

hematologic diseases

,

myeloid leukemia

,

,

liver neoplasms

,

alveolar soft part sarcoma

,

,

healthy volunteers/patients

,

,

,

malignant mesothelioma

,

,

microsatellite instability

,

,

thymus neoplasms

,

cutaneous malignant melanoma

,

biphenotypic leukemia acute

,

waldenstrom macroglobulinemia

,

,

colorectal neoplasms

,

triple negative breast neoplasms

,

,

alzheimer disease

,

multiple myeloma

,

plasma cell neoplasms

,

renal cell carcinoma

,

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

non-hodgkin lymphoma

,

pancreatic neoplasms

,

b-cell lymphoma

,

myelodysplastic syndromes

,

,

kidney neoplasms

,

,

sickle cell anemia

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

large b-cell lymphoma diffuse

,

prostatic neoplasms

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

bone marrow diseases

,

hypercholesterolemia

,

hepatocellular carcinoma

,

,

graft rejection

,

,

castration-resistant prostatic neoplasms

,

neoplasm metastasis

,

invasive hydatidiform mole

,

streptococcal infections

,

inflammatory bowel diseases

,

intestinal diseases

,

,

,

cardiovascular diseases

,

type 2 diabetes mellitus

,

atherosclerosis

,

hyperlipoproteinemia type ii

,

pancreatic ductal carcinoma

,

hematologic neoplasms

,

,

small cell lung carcinoma

,

neuroendocrine tumors

,

head and neck neoplasms

,

mucocutaneous lymph node syndrome

,

endometrial neoplasms

,

hidradenitis suppurativa

,

,

anaplastic thyroid carcinoma

,

,

communicable diseases

,

bacterial infections

,

gram-positive bacterial infections

,

,

smoldering multiple myeloma

,

second primary neoplasms

,

,

japanese encephalitis

,

allergic rhinitis

,

,

myelomonocytic leukemia acute

,

,

female infertility

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

microscopic polyangiitis

,

hemolytic anemia autoimmune

,

hemolytic anemia

,

,

,

breast neoplasms

,

rheumatoid arthritis

,

,

,

non-small-cell lung carcinoma

,

,

psoriatic arthritis

,

,

lymphoid leukemia

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

meningococcal meningitis

,

kidney diseases

,

cryopyrin-associated periodic syndromes

,

b-cell chronic lymphocytic leukemia

,

iga glomerulonephritis

,

spondylarthritis

,

,

,

,

paroxysmal hemoglobinuria

,

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

,

,

,

juvenile arthritis

,

human influenza

,

ankylosing spondylitis

,

precursor cell lymphoblastic leukemia-lymphoma

,

chronic renal insufficiency

,

gouty arthritis

,

,

haemophilus infections

,

thrombocytopenic purpura idiopathic

,

,

,

familial mediterranean fever

,

,

axial spondyloarthritis

,

,

,

,

,

chronic urticaria

,

,

,

,

,

hypersensitivity

,

food hypersensitivity

,

hemolytic-uremic syndrome

,

atypical hemolytic uremic syndrome

,

,

thrombocytopenic purpura

,

,

lupus nephritis

,

,

glomerulonephritis

,

urologic diseases

,

meningococcal infections

,

,

,

kidney transplantation

,

thrombocytopenia

,

macular degeneration

,

renal insufficiency

,

migraine disorders

,

,

wet macular degeneration

,

,

,

tick-borne encephalitis

,

,

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

pulmonary aspergillosis

,

,

,

aplastic anemia

,

chronic progressive multiple sclerosis

Bos taurus adrenal cortex corticosteroids

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

,

,

,

,

atopic dermatitis

,

,

,

ischemic optic neuropathy

,

follicular lymphoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

non-small-cell lung carcinoma

,

,

non-hodgkin lymphoma

,

bullous pemphigoid

,

kidney diseases

,

,

lupus nephritis

,

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

systemic lupus erythematosus

,

neuromyelitis optica

,

,

,

,

breast neoplasms

,

hand-foot syndrome

,

myasthenia gravis

,

muscle weakness

,

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

chronic progressive multiple sclerosis

,

,

,

kidney transplantation

,

,

rheumatoid arthritis

,

liver transplantation

,

juvenile arthritis

,

heart transplantation

,

hypersensitivity

rheumatoid arthritis

,

Histone-arginine methyltransferase carm1

,

respiratory aspiration

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

renal cell carcinoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

multiple myeloma

,

plasma cell neoplasms

,

healthy volunteers/patients

,

rheumatoid arthritis

,

,

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

respiratory tract infections

,

,

tendon injuries

,

anxiety disorders

,

,

,

,

,

,

,

,

chronic hepatitis c

,

chronic hepatitis b

,

,

chronic hepatitis

,

,

,

acquired immunodeficiency syndrome

,

atrial fibrillation

,

,

macular degeneration

,

depressive disorder

,

ovarian neoplasms

,

endometrial neoplasms

,

ovarian epithelial carcinoma

,

immunologic deficiency syndromes

,

,

thrombocytopenia

,

inflammatory breast neoplasms

,

non-small-cell lung carcinoma

,

,

non-hodgkin lymphoma

,

systemic lupus erythematosus

,

,

major depressive disorder

,

,

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

atherosclerosis

,

,

,

,

respiratory syncytial viruses

,

,

pulmonary tuberculosis

,

,

allergic rhinitis

,

allergic rhinitis perennial

,

breast neoplasms

,

,

,

alzheimer disease

,

falciparum malaria

,

,

postmenopausal osteoporosis

,

prostatic hyperplasia

,

,

hypersensitivity

,

dentin sensitivity

,

,

tension-type headache

,

peripheral nervous system diseases

,

diabetic neuropathies

,

,

postoperative nausea and vomiting

,

,

,

,

respiratory sounds

,

allergic rhinitis seasonal

,

,

,

,

,

spinal cord injuries

,

,

erectile dysfunction

,

chronic obstructive pulmonary disease

,

,

,

type 2 diabetes mellitus

,

migraine disorders

,

diabetes mellitus

,

obstructive lung diseases

,

communicable diseases

,

,

bipolar disorder

,

infectious skin diseases

,

insulin resistance

,

metabolic syndrome

,

prostatic neoplasms

,

bacterial infections

,

bacterial skin diseases

,

,

,

soft tissue infections

,

,

,

,

rheumatoid arthritis

,

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