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Therapeutic Areas:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Vyvgart	Efgartigimod alfa	2021-12-17		Myasthenia gravis , Extravasation of diagnostic and therapeutic materials
Vyvgart hytrulo	Efgartigimod alfa, Hyaluronidase	2023-06-20		Extravasation of diagnostic and therapeutic materials , Breast neoplasms , Gastrointestinal neoplasms , Multiple myeloma , Non-small-cell lung carcinoma , Hepatocellular carcinoma , Urinary bladder neoplasms , Melanoma , Small cell lung carcinoma , Alveolar soft part sarcoma , Multiple sclerosis

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

carpal tunnel syndrome

,

,

,

drug hypersensitivity

,

,

myeloid leukemia

,

systemic scleroderma

,

localized scleroderma

,

,

cholangiocarcinoma

,

monocytic leukemia acute

,

autonomic nervous system diseases

,

primary dysautonomias

,

familial dysautonomia

,

castleman disease

,

burkitt lymphoma

,

stomach neoplasms

,

,

,

,

hypercholesterolemia

,

,

,

,

hemolytic anemia

,

ovarian neoplasms

,

,

ovarian epithelial carcinoma

,

bacillary dysentery

,

,

diffuse scleroderma

,

renal insufficiency

,

local anesthesia

,

vitreoretinal surgery

,

myelodysplastic syndromes

,

primary myelofibrosis

,

bcr-abl positive chronic myelogenous leukemia

,

aplastic anemia

,

,

,

pancreatic neoplasms

,

non-hodgkin lymphoma

,

,

,

,

large b-cell lymphoma diffuse

,

hematologic neoplasms

,

myeloid leukemia acute

,

b-cell lymphoma marginal zone

,

hypersensitivity

,

male breast neoplasms

,

hodgkin disease

,

type 2 diabetes mellitus

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

hereditary angioedemas

,

,

stiff-person syndrome

,

urinary bladder neoplasms

,

prostatic neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

esophageal neoplasms

,

graves ophthalmopathy

,

,

thyroid diseases

,

,

cutaneous malignant melanoma

,

neoplasms by site

,

neoplasm micrometastasis

,

muscle spasticity

,

,

,

allergic contact dermatitis

,

,

contact dermatitis

,

retinal diseases

,

vitreous detachment

,

dissociative disorders

,

triple negative breast neoplasms

,

disease progression

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

heart transplantation

,

castration-resistant prostatic neoplasms

,

primary effusion lymphoma

,

peripheral nervous system diseases

,

paraproteinemias

,

polyneuropathies

,

monoclonal gammopathy of undetermined significance

,

renal cell carcinoma

,

,

,

multiple myeloma

,

plasma cell neoplasms

,

breast neoplasms

,

,

non-small-cell lung carcinoma

,

,

,

b-cell lymphoma

,

follicular lymphoma

,

,

postoperative pain

,

pancreatic ductal carcinoma

,

immunoglobulin light-chain amyloidosis

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

polyradiculoneuropathy

,

,

mantle-cell lymphoma

,

,

diabetic retinopathy

,

smoldering multiple myeloma

,

residual neoplasm

,

,

vitreous hemorrhage

,

,

ductal carcinoma

,

,

oral submucous fibrosis

,

cardiovascular diseases

,

myocardial infarction

,

coronary disease

,

myocardial ischemia

,

,

,

endometrial neoplasms

,

endometrioid carcinoma

,

serous cystadenocarcinoma

,

clear cell adenocarcinoma

,

,

acinar cell carcinoma

,

mullerian mixed tumor

,

inflammatory breast neoplasms

,

healthy volunteers/patients

,

immunologic deficiency syndromes

,

primary immunodeficiency diseases

,

diabetes mellitus

,

,

type 1 diabetes mellitus

,

,

,

,

,

injection site reaction

,

,

,

,

cardiac arrhythmias

,

,

,

rheumatoid arthritis

,

,

,

surgical wound infection

,

,

,

ocular hypotension

,

,

wounds and injuries

,

,

,

failed back surgery syndrome

,

,

intermittent claudication

,

pathologic constriction

,

spinal stenosis

,

neoplasm metastasis

,

intraocular pressure

,

myofascial pain syndromes

,

,

somatoform disorders

,

,

pneumococcal pneumonia

,

invasive hydatidiform mole

,

,

prostatic hyperplasia

,

,

pain management

,

spinal diseases

,

,

,

,

,

,

,

,

,

,

rectal neoplasms

,

intervertebral disc displacement

Hyaluronidase (human recombinant)

myeloid leukemia acute

,

myeloid leukemia

,

cholangiocarcinoma

,

monocytic leukemia acute

,

castleman disease

,

burkitt lymphoma

,

multiple sclerosis

,

,

stomach neoplasms

,

hypercholesterolemia

,

,

ovarian neoplasms

,

,

ovarian epithelial carcinoma

,

myelodysplastic syndromes

,

primary myelofibrosis

,

precursor cell lymphoblastic leukemia-lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

aplastic anemia

,

,

,

pancreatic neoplasms

,

,

non-hodgkin lymphoma

,

,

,

b-cell lymphoma marginal zone

,

male breast neoplasms

,

alzheimer disease

,

type 2 diabetes mellitus

,

large b-cell lymphoma diffuse

,

b-cell chronic lymphocytic leukemia

,

hereditary angioedemas

,

,

urinary bladder neoplasms

,

hematologic neoplasms

,

prostatic neoplasms

,

hodgkin disease

,

esophageal neoplasms

,

,

cutaneous malignant melanoma

,

neoplasms by site

,

lymphoid leukemia

,

muscle spasticity

,

,

,

allergic contact dermatitis

,

,

contact dermatitis

,

triple negative breast neoplasms

,

heart transplantation

,

urologic neoplasms

,

transitional cell carcinoma

,

castration-resistant prostatic neoplasms

,

peripheral nervous system diseases

,

paraproteinemias

,

polyneuropathies

,

monoclonal gammopathy of undetermined significance

,

multiple myeloma

,

plasma cell neoplasms

,

breast neoplasms

,

,

,

b-cell lymphoma

,

non-small-cell lung carcinoma

,

,

,

follicular lymphoma

,

,

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

polyradiculoneuropathy

,

pancreatic ductal carcinoma

,

mantle-cell lymphoma

,

,

immunoglobulin light-chain amyloidosis

,

,

bullous pemphigoid

,

,

dermatomyositis

,

muscular diseases

,

,

smoldering multiple myeloma

,

renal cell carcinoma

,

ductal carcinoma

,

residual neoplasm

,

,

endometrial neoplasms

,

endometrioid carcinoma

,

serous cystadenocarcinoma

,

clear cell adenocarcinoma

,

,

acinar cell carcinoma

,

mullerian mixed tumor

,

inflammatory breast neoplasms

,

healthy volunteers/patients

,

immunologic deficiency syndromes

,

primary immunodeficiency diseases

,

diabetes mellitus

,

type 1 diabetes mellitus

,

,

,

rheumatoid arthritis

,

,

,

,

stiff-person syndrome

,

neoplasm metastasis

,

,

pneumococcal pneumonia

,

invasive hydatidiform mole

,

,

pain management

,

,

,

rectal neoplasms

,

,

,

enterovirus infections

,

ocular hypertension

,

open-angle glaucoma

,

,

Vorhyaluronidase alfa

alzheimer disease

Sodium chloride

healthy volunteers/patients

,

,

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

,

,

pulmonary eosinophilia

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

migraine disorders

,

sleep wake disorders

short bowel syndrome

,

nasopharyngeal carcinoma

,

,

myeloid leukemia acute

,

myeloid leukemia

,

myelodysplastic syndromes

,

,

,

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

guillain-barre syndrome

,

,

polyneuropathies

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

myeloid leukemia acute

,

myeloid leukemia

,

myelodysplastic syndromes

,

,

,

hiv-associated lipodystrophy syndrome

,

colorectal neoplasms

,

waldenstrom macroglobulinemia

,

plasmablastic lymphoma

,

large-cell lymphoma immunoblastic

,

lymphomatoid granulomatosis

,

pancreatic neoplasms

,

haemophilus influenzae

,

ductal carcinoma

,

breast neoplasms

,

bacterial pneumonia

,

inflammatory bowel diseases

,

intestinal diseases

,

,

follicular lymphoma

,

b-cell lymphoma

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

prolymphocytic leukemia t-cell

,

b-cell lymphoma marginal zone

,

mantle-cell lymphoma

,

,

,

,

urinary bladder neoplasms

,

,

hematologic diseases

,

,

t-cell lymphoma

,

ovarian neoplasms

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

myelodysplastic syndromes

,

bcr-abl positive chronic myelogenous leukemia

,

hodgkin disease

,

respiratory distress syndrome

,

,

severe acute respiratory syndrome

,

,

hepatocellular carcinoma

,

liver neoplasms

,

cholangiocarcinoma

,

escherichia coli infections

,

,

common variable immunodeficiency

,

immune tolerance

,

colonic neoplasms

,

,

prostatic neoplasms

,

,

multiple chronic conditions

,

salmonella infections

,

neisseria meningitidis

,

,

,

meningococcal meningitis

,

,

rotavirus infections

,

multiple sclerosis

,

,

large b-cell lymphoma diffuse

,

otitis media with effusion

,

acquired immunodeficiency syndrome

,

,

,

viral hemorrhagic fevers

,

relapsing-remitting multiple sclerosis

,

haemophilus infections

,

tympanic membrane perforation

,

,

invasive hydatidiform mole

,

,

ataxia telangiectasia

,

,

cerebellar ataxia

,

autonomic nervous system diseases

,

,

,

,

,

,

japanese encephalitis

,

antibody formation

,

bacterial meningitis

,

,

organ transplantation

,

hematopoietic stem cell transplantation

,

respiratory syncytial virus infections

,

pneumococcal infections

,

pneumococcal pneumonia

,

,

streptococcal infections

,

,

healthy volunteers/patients

,

communicable diseases

,

human influenza

,

streptococcus pneumoniae

,

,

,

haemophilus influenzae type b

,

,

meningococcal infections

,

,

,

,

,

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

b-cell chronic lymphocytic leukemia

,

,

lymphoid leukemia

,

,

rheumatoid arthritis

,

,

,

,

bacterial infections

,

,

,

,

,

,

chronic obstructive pulmonary disease

,

,

,

,

,

,

obstructive lung diseases

,

,

,

non-hodgkin lymphoma

,

systemic lupus erythematosus

,

diabetes mellitus

,

type 1 diabetes mellitus

,

sickle cell anemia

,

premature birth

,

,

,

,

,

respiratory tract infections

,

kidney diseases

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

systemic vasculitis

,

,

immune system diseases

,

immunologic deficiency syndromes

,

respiratory tract diseases

,

kidney transplantation

,

,

,

vaccine immunogenicity

,

beta-thalassemia

,

,

chronic renal insufficiency

,

chronic kidney failure

,

,

,

immunosuppression therapy

,

,

,

,

febrile neutropenia

,

juvenile arthritis

,

spondylarthropathies

,

nephrotic syndrome

,

,

lipoid nephrosis

,

combination drug therapy

,

primary immunodeficiency diseases

,

myeloid leukemia acute

,

sjogren's syndrome

,

rheumatic diseases

,

spondylarthritis

,

,

collagen diseases

,

neonatal anemia

,

febrile seizures

,

renal insufficiency

,

respiration disorders

,

liver transplantation

,

,

,

hepatitis a virus

,

transplantation

,

bone marrow transplantation

,

coronavirus infections

,

,

covid-19 vaccines

,

,

severe acute malnutrition

,

nasopharyngeal neoplasms

,

vaccine-preventable diseases

,

drug-related side effects and adverse reactions

,

,

ulcerative colitis

,

,

,

,

,

immunologic memory

,

,

,

,

,

systemic scleroderma

,

nasopharyngeal diseases

,

intestinal neoplasms

,

procedural pain

,

,

pneumococcal meningitis

,

pleural effusion

,

pharmacokinetics

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

positron-emission tomography

,

,

alzheimer disease

,

diagnostic imaging

,

medical sociology

,

,

,

drug interactions

,

electrocardiography

,

therapeutic equivalency

,

pharmacological phenomena

,

,

,

stomach neoplasms

,

hypophosphatemia

,

hematologic neoplasms

,

respiratory aspiration

,

cystic fibrosis

,

pseudomonas infections

,

biological availability

,

castration-resistant prostatic neoplasms

,

,

non-small-cell lung carcinoma

,

,

breast neoplasms

,

postcoital contraception

,

ovulation inhibition

,

atrial fibrillation

,

,

parkinson disease

,

small cell lung carcinoma

,

ovarian neoplasms

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

,

cardiomyopathies

,

,

,

,

overactive urinary bladder

,

hormonal contraception

,

unplanned pregnancy

,

b-cell lymphoma

,

,

skin abnormalities

,

myocardial infarction

,

,

,

acquired immunodeficiency syndrome

,

magnetic resonance angiography

,

,

left ventricular dysfunction

,

ventricular dysfunction

,

interstitial lung diseases

,

ovarian epithelial carcinoma

,

thyroid neoplasms

,

thyroid diseases

,

pancreatic neoplasms

,

,

,

,

,

prostatic hyperplasia

,

,

angina pectoris

,

,

ischemic stroke

,

,

cerebral infarction

,

urologic neoplasms

,

head and neck neoplasms

,

thromboembolism

,

venous thromboembolism

,

pulmonary hypertension

,

,

hyperphosphatemia

,

,

prostatic neoplasms

,

,

venous thrombosis

,

non-hodgkin lymphoma

,

,

chronic renal insufficiency

,

kidney diseases

,

surgical blood loss

,

,

,

vascular diseases

,

peripheral arterial disease

,

peripheral vascular diseases

,

postoperative hemorrhage

,

pulmonary embolism

,

,

cardiovascular diseases

,

,

,

spinal cord injuries

,

pathologic constriction

,

renal artery obstruction

,

,

bacterial infections

,

esophageal neoplasms

,

,

,

intraabdominal infections

,

,

chronic progressive multiple sclerosis

,

blood coagulation disorders

,

hemostatic disorders

,

hormone replacement therapy

,

hyperlipidemias

,

hyperlipoproteinemias

,

choroidal neovascularization

,

,

degenerative myopia

,

pathologic neovascularization

,

,

aspiration pneumonia

,

,

,

pelvic infection

,

pelvic inflammatory disease

,

,

metabolic bone diseases

,

,

premenstrual dysphoric disorder

,

diabetic nephropathies

,

,

follicular lymphoma

,

wounds and injuries

,

brain neoplasms

,

congenital abnormalities

,

cardiovascular abnormalities

,

,

memory disorders

,

carotid stenosis

,

pulmonary arterial hypertension

,

,

,

depressive disorder

,

hypersensitivity

,

aortic valve stenosis

,

heart valve diseases

,

ventricular outflow obstruction

,

abdominal abscess

,

erectile dysfunction

,

,

,

,

,

,

,

healthy volunteers/patients

,

renal cell carcinoma

,

communicable diseases

,

multiple sclerosis

,

,

,

,

essential hypertension

,

atopic dermatitis

,

,

liver neoplasms

,

,

relapsing-remitting multiple sclerosis

,

,

hepatocellular carcinoma

,

urinary tract infections

,

diabetes mellitus

,

coronary artery disease

,

,

type 2 diabetes mellitus

,

colorectal neoplasms

,

,

,

,

physiological sexual dysfunction

,

magnetic resonance imaging

,

neoplasm metastasis

,

coronary disease

,

acute coronary syndrome

,

myocardial ischemia

,

,

tension-type headache

,

,

,

renal insufficiency

,

chronic bronchitis

,

,

,

,

,

respiratory tract infections

,

,

peripheral nervous system diseases

,

ischemic optic neuropathy

,

optic nerve diseases

,

,

,

macular degeneration

,

energy metabolism

,

,

maxillary sinusitis

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

medicated intrauterine devices

,

,

gene expression

,

cell proliferation

,

,

central nervous system neoplasms

,

photoallergic dermatitis

,

phototoxic dermatitis

,

four-dimensional computed tomography

healthy volunteers/patients

,

myeloid leukemia acute

,

myeloid leukemia

,

myelodysplastic syndromes

,

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

congenital abnormalities

,

chromosome aberrations

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

renal cell carcinoma

,

non-small-cell lung carcinoma

,

,

colorectal neoplasms

,

multiple myeloma

,

,

pancreatic neoplasms

,

primary myelofibrosis

,

sjogren's syndrome

,

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

plasma cell neoplasms

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

,

oligodendroglioma

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

chronic hepatitis c

,

chronic hepatitis

,

pancreatic ductal carcinoma

,

,

,

graft rejection

,

,

falciparum malaria

,

,

triple negative breast neoplasms

,

gastrointestinal neoplasms

,

gastrointestinal stromal tumors

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

neoplasm micrometastasis

,

uterine cervical neoplasms

,

,

hematologic neoplasms

,

meningococcal infections

,

,

,

human influenza

,

breast neoplasms

,

,

chronic urticaria

,

,

,

,

haemophilus infections

,

liver transplantation

,

,

,

chronic renal insufficiency

,

kidney diseases

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

psoriatic arthritis

,

,

influenza in birds

,

,

gouty arthritis

,

,

,

autoimmune hepatitis

,

juvenile arthritis

,

h5n1 subtype influenza a virus

,

,

hyperphosphatemia

,

,

communicable diseases

,

,

chronic hepatitis b

,

chronic disease

,

,

cryopyrin-associated periodic syndromes

,

,

lupus nephritis

,

,

,

,

kidney transplantation

,

,

,

tick-borne encephalitis

,

,

,

cystic fibrosis

1

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