CUSATUZUMAB
Cusatuzumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target CD70 antigen.
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FDA approval date
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Study first post date
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Commercial
No data
Clinical
Clinical Trials
8 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | 3 | 3 | — | — | — | 5 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 3 | 3 | — | — | — | 5 |
| Myeloid leukemia | D007951 | — | C92 | 3 | 3 | — | — | — | 5 |
| Myelodysplastic syndromes | D009190 | — | D46 | 2 | 2 | — | — | — | 3 |
| Preleukemia | D011289 | — | — | 1 | 1 | — | — | — | 2 |
| Syndrome | D013577 | — | — | 1 | 2 | — | — | — | 2 |
| Neoplasms | D009369 | — | C80 | 2 | 1 | — | — | — | 2 |
| Myelomonocytic leukemia chronic | D015477 | — | C93.1 | — | 1 | — | — | — | 1 |
| Myelomonocytic leukemia juvenile | D054429 | — | C93.3 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Nasopharyngeal carcinoma | D000077274 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | CUSATUZUMAB |
| INN | cusatuzumab |
| Description | Cusatuzumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target CD70 antigen. |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297891 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | RR5U4UFJ8L (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
CD70
CD70
Organism
Homo sapiens
Gene name
CD70
Gene synonyms
CD27L, CD27LG, TNFSF7
NCBI Gene ID
Protein name
CD70 antigen
Protein synonyms
CD27 ligand, CD27-L, CD70, Ki-24 antigen, surface antigen CD70, tumor necrosis factor ligand 8A, Tumor necrosis factor ligand superfamily member 7
Uniprot ID
Mouse ortholog
Cd70 (21948)
CD70 antigen (O55237)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 135 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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28 adverse events reported
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