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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

neoplasm metastasis

,

multiple myeloma

,

squamous cell carcinoma

,

,

squamous cell carcinoma of head and neck

,

squamous cell neoplasms

,

,

triple negative breast neoplasms

,

head and neck neoplasms

,

colorectal neoplasms

,

,

breast neoplasms

,

urinary bladder neoplasms

,

non-hodgkin lymphoma

,

b-cell lymphoma

,

renal cell carcinoma

,

,

endometrial neoplasms

,

small cell carcinoma

,

uterine cervical neoplasms

,

urologic neoplasms

,

transitional cell carcinoma

,

,

pancreatic neoplasms

,

cholangiocarcinoma

,

stomach neoplasms

,

rectal neoplasms

,

,

,

,

brain stem neoplasms

,

phenylketonurias

,

,

follicular lymphoma

,

brain neoplasms

,

,

microsatellite instability

,

tertiary lymphoid structures

,

spinocerebellar degenerations

,

non-small-cell lung carcinoma

,

,

small cell lung carcinoma

,

esophageal neoplasms

,

liver neoplasms

,

hepatocellular carcinoma

,

esophageal squamous cell carcinoma

urinary bladder neoplasms

,

glandular and epithelial neoplasms

,

,

,

,

,

multiple myeloma

,

neoplasms by histologic type

,

urinary bladder diseases

,

,

myeloid leukemia acute

,

gata2 deficiency

,

pancreatic neoplasms

,

colorectal neoplasms

,

,

colonic neoplasms

,

cutaneous malignant melanoma

,

prostatic neoplasms

,

,

transitional cell carcinoma

,

liver neoplasms

,

small cell lung carcinoma

,

pancreatic ductal carcinoma

,

,

urologic neoplasms

,

stomach neoplasms

,

endometrial neoplasms

,

,

squamous cell carcinoma

,

,

neoplasms by site

,

rectal neoplasms

,

ovarian neoplasms

,

,

biliary tract neoplasms

,

hepatocellular carcinoma

,

,

microsatellite instability

,

,

non-hodgkin lymphoma

,

hodgkin disease

,

uterine cervical neoplasms

,

follicular lymphoma

,

,

squamous cell neoplasms

,

female genital neoplasms

,

endometrioid carcinoma

,

spinocerebellar degenerations

,

neuroendocrine tumors

,

gastrointestinal neoplasms

,

adenocarcinoma of lung

,

basal cell carcinoma

,

basal cell neoplasms

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

t-cell lymphoma peripheral

,

oropharyngeal neoplasms

,

prostatic diseases

,

cholangiocarcinoma

,

diffuse intrinsic pontine glioma

,

hematologic neoplasms

,

b-cell chronic lymphocytic leukemia

,

bile duct neoplasms

,

genetic therapy

,

smoldering multiple myeloma

,

,

urogenital neoplasms

,

small cell carcinoma

,

penile neoplasms

,

adrenocortical carcinoma

,

,

drug-related side effects and adverse reactions

,

,

precancerous conditions

,

bronchopulmonary dysplasia

,

tobacco smoking

,

b-cell lymphoma marginal zone

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

large b-cell lymphoma diffuse

,

burkitt lymphoma

,

oligodendroglioma

,

merkel cell carcinoma

,

hereditary nonpolyposis colorectal neoplasms

,

b-cell lymphoma

,

,

,

non-small-cell lung carcinoma

,

,

neoplasm metastasis

,

squamous cell carcinoma of head and neck

,

renal cell carcinoma

,

,

breast neoplasms

,

head and neck neoplasms

,

brain neoplasms

,

kidney neoplasms

,

triple negative breast neoplasms

,

,

fallopian tube neoplasms

,

ovarian epithelial carcinoma

,

pathologic complete response

,

b-cell chronic lymphocytic leukemia

healthy volunteers/patients

,

,

central nervous system neoplasms

,

nephrotic syndrome

,

laryngeal diseases

,

chronic hepatitis

,

,

esophageal neoplasms

,

postmenopausal osteoporosis

,

,

irritable bowel syndrome

,

pathologic dilatation

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

,

,

choroid plexus neoplasms

,

oligodendroglioma

,

primitive neuroectodermal tumors

,

,

,

neuroepithelial neoplasms

,

hypertrophic pyloric stenosis

,

ganglioneuroblastoma

,

phenylketonurias

,

neuroendocrine tumors

,

b-cell lymphoma marginal zone

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

rectal diseases

,

gastrointestinal diseases

,

intestinal neoplasms

,

digestive system diseases

,

colonic diseases

,

intestinal diseases

,

autism spectrum disorder

,

drug hypersensitivity

,

renal cell carcinoma

,

,

,

squamous cell carcinoma of head and neck

,

head and neck neoplasms

,

b-cell lymphoma

,

squamous cell carcinoma

,

large b-cell lymphoma diffuse

,

pancreatic ductal carcinoma

,

,

,

uveal neoplasms

,

,

mantle-cell lymphoma

,

myocardial infarction

,

kidney neoplasms

,

hereditary sensory and autonomic neuropathies

,

myelodysplastic syndromes

,

endometrial neoplasms

,

bronchiolitis obliterans syndrome

,

hypersensitivity

,

philadelphia chromosome

,

lymphoid leukemia

,

,

squamous cell neoplasms

,

waldenstrom macroglobulinemia

,

myeloid leukemia acute

,

multiple myeloma

,

castration-resistant prostatic neoplasms

,

hypertrophic cardiomyopathy

,

acute coronary syndrome

,

myocardial ischemia

,

unstable angina

,

margins of excision

,

gouty arthritis

,

gastrointestinal stromal tumors

,

,

,

retinitis pigmentosa

,

,

,

,

,

coronary artery disease

,

,

portal hypertension

,

atopic dermatitis

,

,

,

,

peritoneal neoplasms

,

intestinal obstruction

,

invasive hydatidiform mole

,

central serous chorioretinopathy

,

,

epstein-barr virus infections

,

oropharyngeal neoplasms

,

hodgkin disease

,

type 1 diabetes mellitus

,

,

neurofibrosarcoma

,

ovarian neoplasms

,

fallopian tube neoplasms

,

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

netherton syndrome

,

,

eosinophilic esophagitis

,

,

systemic mastocytosis

,

mast-cell leukemia

,

,

,

female infertility

,

sickle cell anemia

,

streptococcus agalactiae

,

angioid streaks

,

pseudoxanthoma elasticum

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

microscopic polyangiitis

,

diffuse scleroderma

,

t-cell lymphoma

,

malignant mesothelioma

,

clear cell adenocarcinoma

,

,

adenomyoepithelioma

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

prostatic neoplasms

,

,

myeloid leukemia

,

triple negative breast neoplasms

,

,

follicular lymphoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

cardiovascular diseases

,

graft vs host disease

,

,

psoriatic arthritis

,

,

rheumatoid arthritis

,

meningococcal meningitis

,

meningococcal infections

,

hypercholesterolemia

,

rectal neoplasms

,

osteitis deformans

,

,

degenerative myopia

,

non-hodgkin lymphoma

,

stomach neoplasms

,

,

neoplasms by site

,

inferior wall myocardial infarction

,

,

psychology rejection

,

organ transplantation

,

graft rejection

,

adenocarcinoma of lung

,

,

aplastic anemia

,

,

carcinoid tumor

,

,

chronic hepatitis c

,

lupus nephritis

,

,

colonic neoplasms

,

retinopathy of prematurity

,

polycythemia vera

,

male breast neoplasms

,

,

,

,

hematologic neoplasms

,

neoplasms by histologic type

,

left ventricular dysfunction

,

st elevation myocardial infarction

,

non-st elevated myocardial infarction

,

,

,

,

infectious skin diseases

,

soft tissue infections

,

,

malignant carcinoid syndrome

,

serotonin syndrome

,

erectile dysfunction

,

peanut hypersensitivity

,

allergic rhinitis seasonal

,

,

,

haemophilus infections

,

,

cerebrotendinous xanthomatosis

,

,

muscular atrophy

,

spinal muscular atrophy

,

,

neovascular glaucoma

,

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

chronic obstructive pulmonary disease

,

,

alpha 1-antitrypsin deficiency

,

lymphoproliferative disorders

,

primary myelofibrosis

,

,

breast neoplasms

,

,

macular degeneration

,

,

,

,

kidney transplantation

,

vision disorders

,

choroidal neovascularization

,

type 2 diabetes mellitus

,

neoplasm metastasis

,

retinal vein occlusion

,

chronic urticaria

,

diabetes mellitus

,

liver transplantation

,

essential hypertension

,

multiple sclerosis

,

diabetic retinopathy

,

brain neoplasms

,

relapsing-remitting multiple sclerosis

,

kidney diseases

,

metabolic syndrome

,

renal insufficiency

,

,

pancreatic neoplasms

,

,

chronic kidney failure

,

,

retinal diseases

,

systolic heart failure

,

insulin resistance

,

,

geographic atrophy

,

parkinson disease

,

diastolic heart failure

,

chronic renal insufficiency

,

,

diabetic nephropathies

,

wet macular degeneration

,

,

,

retinal neovascularization

,

polypoidal choroidal vasculopathy

,

liver cirrhosis

,

,

diabetes complications

,

isolated systolic hypertension

,

systolic murmurs

,

,

left ventricular hypertrophy

,

,

glucose intolerance

,

,

chronic progressive multiple sclerosis

,

,

,

membranous glomerulonephritis

,

,

,

pathologic neovascularization

,

tick-borne encephalitis

,

,

,

,

renal replacement therapy

,

,

prehypertension

,

,

staphylococcal skin infections

,

,

,

neurobehavioral manifestations

,

heart transplantation

,

pituitary acth hypersecretion

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

,

pituitary neoplasms

,

,

sexual infantilism

,

heart-lung transplantation

,

,

coronavirus infections

,

,

polyomavirus infections

,

retinal detachment

,

atrial fibrillation

,

iga glomerulonephritis

,

focal segmental glomerulosclerosis

,

nephrosclerosis

,

allergic conjunctivitis

,

reperfusion injury

,

delayed graft function

,

food hypersensitivity

,

islet cell adenoma

,

metabolic bone diseases

,

cryopyrin-associated periodic syndromes

,

,

,

,

immunosuppression therapy

,

angina pectoris

,

microvascular angina

,

spinal muscular atrophies of childhood

,

hematopoietic stem cell transplantation

Globulin, immune

inflammatory breast neoplasms

,

,

,

,

,

oligodendroglioma

,

small cell lung carcinoma

,

paroxysmal hemoglobinuria

,

,

stomach neoplasms

,

neoplasm metastasis

,

non-hodgkin lymphoma

,

esophageal neoplasms

,

hodgkin disease

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

liver neoplasms

,

squamous cell carcinoma of head and neck

,

,

,

hepatocellular carcinoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

pancreatic neoplasms

,

prolymphocytic leukemia

,

prostatic neoplasms

,

ovarian neoplasms

,

graft rejection

,

bronchiolitis obliterans syndrome

,

hypercholesterolemia

,

h1n1 subtype influenza a virus

,

biliary tract neoplasms

,

renal cell carcinoma

,

,

,

triple negative breast neoplasms

,

head and neck neoplasms

,

atopic dermatitis

,

basal cell carcinoma

,

basal cell neoplasms

,

type 1 diabetes mellitus

,

heart transplantation

,

aplastic anemia

,

fallopian tube neoplasms

,

rectal neoplasms

,

pancreatic ductal carcinoma

,

induction chemotherapy

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

renal insufficiency

,

brain neoplasms

,

follicular lymphoma

,

,

lymphoid leukemia

,

meningococcal meningitis

,

neisseria meningitidis

,

west nile fever

,

systemic scleroderma

,

diffuse scleroderma

,

refractory anemia with excess of blasts

,

refractory anemia

,

esophageal squamous cell carcinoma

,

uterine cervical neoplasms

,

,

,

paraproteinemias

,

monoclonal gammopathy of undetermined significance

,

ovarian epithelial carcinoma

,

squamous cell carcinoma

,

squamous cell neoplasms

,

prolymphocytic leukemia t-cell

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

uveal neoplasms

,

,

sezary syndrome

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

,

hyperlipoproteinemia type ii

,

,

t-cell lymphoma peripheral

,

laryngeal neoplasms

,

stem cell transplantation

,

colonic neoplasms

,

multiple myeloma

,

breast neoplasms

,

,

non-small-cell lung carcinoma

,

,

b-cell chronic lymphocytic leukemia

,

plasma cell neoplasms

,

colorectal neoplasms

,

myelodysplastic syndromes

,

,

myeloid leukemia acute

,

,

graft vs host disease

,

,

,

meningococcal infections

,

human influenza

,

,

hematologic neoplasms

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

thrombotic thrombocytopenic purpura

,

immune system diseases

,

rheumatoid arthritis

,

,

haemophilus influenzae type b

,

reperfusion injury

,

,

neuroendocrine tumors

,

carcinoid tumor

,

,

paraneoplastic syndromes

,

islet cell carcinoma

,

islet cell adenoma

,

,

,

somatostatinoma

,

respiratory hypersensitivity

,

,

,

glomerulonephritis

,

haemophilus infections

,

myeloid leukemia

,

autoimmune diseases

,

nervous system diseases

,

autoimmune diseases of the nervous system

,

demyelinating diseases

,

cns demyelinating autoimmune diseases

,

myeloproliferative disorders

,

chronic inflammatory demyelinating polyradiculoneuropathy

,

multiple sclerosis

,

,

,

relapsing-remitting multiple sclerosis

,

kidney transplantation

,

,

chronic kidney failure

,

,

,

,

glycogen storage disease type ii

,

,

liver transplantation

,

psychology rejection

,

transplantation

,

immunosuppression therapy

,

,

glycogen storage disease type iii

,

,

mucopolysaccharidosis i

,

kidney diseases

,

b-cell leukemia

,

,

clostridium infections

,

vaccine immunogenicity

,

pathologic processes

,

healthy volunteers/patients

,

hodgkin disease

,

myeloid leukemia acute

,

breast neoplasms

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

,

chemotherapy-induced febrile neutropenia

,

non-hodgkin lymphoma

,

,

mantle-cell lymphoma

,

promyelocytic leukemia acute

ovarian neoplasms

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

rhabdomyosarcoma

,

disease progression

,

,

non-hodgkin lymphoma

,

breast neoplasms

,

myelodysplastic syndromes

,

lymphoid leukemia

,

thoracic neoplasms

,

neurologic manifestations

,

papillomaviridae

,

pharmacokinetics

,

soft tissue neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

respiratory tract neoplasms

,

bronchogenic carcinoma

,

endocrine gland neoplasms

,

breast diseases

,

bronchial neoplasms

,

intraductal carcinoma noninfiltrating

,

laryngeal diseases

,

,

oligodendroglioma

,

,

pancreatic neoplasms

,

,

brain neoplasms

,

castration-resistant prostatic neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

non-hodgkin lymphoma

,

t-cell lymphoma

,

myeloid leukemia acute

,

follicular lymphoma

,

,

kidney neoplasms

,

neuroendocrine tumors

,

pancreatic ductal carcinoma

,

t-cell lymphoma peripheral

,

microsatellite instability

,

uveal neoplasms

,

,

invasive hydatidiform mole

,

neuroendocrine carcinoma

,

,

thyroid neoplasms

,

myeloid leukemia

,

urethral neoplasms

,

colonic neoplasms

,

uterine neoplasms

,

gastrointestinal neoplasms

,

mouth neoplasms

,

oropharyngeal neoplasms

,

small cell carcinoma

,

vulvar neoplasms

,

b-cell lymphoma marginal zone

,

,

female genital neoplasms

,

hypersensitivity

,

,

epstein-barr virus infections

,

microsatellite repeats

,

rectal neoplasms

,

hypopharyngeal neoplasms

,

salivary gland neoplasms

,

endometrioid carcinoma

,

serous cystadenocarcinoma

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

non-muscle invasive bladder neoplasms

,

penile neoplasms

,

neoplasms by histologic type

,

,

b-cell chronic lymphocytic leukemia

,

t-cell lymphoma cutaneous

,

ureteral neoplasms

,

,

,

,

,

thymus neoplasms

,

burkitt lymphoma

,

laryngeal neoplasms

,

,

adenoid cystic carcinoma

,

,

glandular and epithelial neoplasms

,

male breast neoplasms

,

,

adenocarcinoma of lung

,

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

mycosis fungoides

,

,

pelvic neoplasms

,

central nervous system neoplasms

,

germ cell and embryonal neoplasms

,

digestive system neoplasms

,

basal cell carcinoma

,

thyroid diseases

,

reactive arthritis

,

mullerian mixed tumor

,

adenosquamous carcinoma

,

gestational trophoblastic disease

,

alveolar soft part sarcoma

,

biphenotypic leukemia acute

,

local neoplasm recurrence

,

,

,

meningeal carcinomatosis

,

immunoblastic lymphadenopathy

,

enteropathy-associated t-cell lymphoma

,

,

carcinoma in situ

,

cervical intraepithelial neoplasia

,

uterine cervical dysplasia

,

squamous intraepithelial lesions of the cervix

,

disease progression

,

central nervous system diseases

,

extranodal nk-t-cell lymphoma

,

neoplasms by site

,

x-linked bulbo-spinal atrophy

,

malignant fibrous histiocytoma

,

nasopharyngeal carcinoma

,

,

,

unknown primary neoplasms

,

synovial sarcoma

,

,

oral leukoplakia

,

,

hematologic diseases

,

bone marrow diseases

,

,

sezary syndrome

,

,

colonic diseases

,

histiocytic sarcoma

,

follicular dendritic cell sarcoma

,

interdigitating dendritic cell sarcoma

,

environmental biomarkers

,

circulating neoplastic cells

,

inflammatory breast neoplasms

,

meningeal neoplasms

,

intestinal neoplasms

,

nervous system neoplasms

,

kidney diseases

,

nervous system diseases

,

nerve tissue neoplasms

,

neuroepithelial neoplasms

,

neuroectodermal tumors

,

anaplastic thyroid carcinoma

,

adrenocortical carcinoma

,

carcinoid tumor

,

parotid neoplasms

,

mediastinal neoplasms

,

testicular neoplasms

,

male genital neoplasms

,

gastrointestinal stromal tumors

,

hairy cell leukemia

,

vaginal neoplasms

,

spinal cord neoplasms

,

acinar cell carcinoma

,

adenoviridae infections

,

,

hereditary breast and ovarian cancer syndrome

,

basal cell neoplasms

,

urogenital neoplasms

,

male urogenital diseases

,

hemangiosarcoma

,

perivascular epithelioid cell neoplasms

,

,

,

,

breast neoplasms

,

colorectal neoplasms

,

triple negative breast neoplasms

,

squamous cell carcinoma

,

renal cell carcinoma

,

ovarian neoplasms

,

urinary bladder neoplasms

,

neoplasm metastasis

,

stomach neoplasms

,

head and neck neoplasms

,

,

,

prostatic neoplasms

,

liver neoplasms

,

hepatocellular carcinoma

,

esophageal neoplasms

,

endometrial neoplasms

,

uterine cervical neoplasms

,

transitional cell carcinoma

,

small cell lung carcinoma

,

hodgkin disease

,

urologic neoplasms

,

fallopian tube neoplasms

,

multiple myeloma

,

,

ovarian epithelial carcinoma

,

squamous cell neoplasms

,

,

biliary tract neoplasms

,

cholangiocarcinoma

,

esophageal squamous cell carcinoma

,

,

plasma cell neoplasms

,

malignant mesothelioma

,

peritoneal neoplasms

,

merkel cell carcinoma

,

cutaneous malignant melanoma

,

hematologic neoplasms

,

nasopharyngeal neoplasms

,

bile duct neoplasms

,

gallbladder neoplasms

,

non-small-cell lung carcinoma

,

,

squamous cell carcinoma of head and neck

liver neoplasms

,

esophageal squamous cell carcinoma

,

renal cell carcinoma

,

non-small-cell lung carcinoma

,

breast neoplasms

,

hepatocellular carcinoma

,

,

colorectal neoplasms

breast neoplasms

,

,

triple negative breast neoplasms

pancreatic neoplasms

,

small cell lung carcinoma

,

small cell carcinoma

,

urethral neoplasms

,

pharmacokinetics

,

non-hodgkin lymphoma

,

,

hodgkin disease

,

follicular lymphoma

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

castration-resistant prostatic neoplasms

,

head and neck neoplasms

,

,

hepatocellular carcinoma

,

squamous cell neoplasms

,

renal cell carcinoma

,

urologic neoplasms

,

colorectal neoplasms

,

,

liver neoplasms

,

transitional cell carcinoma

,

invasive hydatidiform mole

,

,

male breast neoplasms

,

cholangiocarcinoma

,

gallbladder neoplasms

,

hereditary breast and ovarian cancer syndrome

,

,

mouth neoplasms

,

oropharyngeal neoplasms

,

neoplasms by histologic type

,

neoplasms by site

,

glandular and epithelial neoplasms

,

hypopharyngeal neoplasms

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

,

,

,

endometrioid carcinoma

,

nasopharyngeal carcinoma

,

laryngeal neoplasms

,

pancreatic ductal carcinoma

,

biliary tract neoplasms

,

adenosquamous carcinoma

,

,

non-small-cell lung carcinoma

,

breast neoplasms

,

triple negative breast neoplasms

,

ovarian neoplasms

,

,

,

endometrial neoplasms

,

stomach neoplasms

,

esophageal neoplasms

,

,

prostatic neoplasms

,

neoplasm metastasis

,

fallopian tube neoplasms

,

uterine cervical neoplasms

,

squamous cell carcinoma

,

ovarian epithelial carcinoma

,

esophageal squamous cell carcinoma

,

,

urinary bladder neoplasms

,

peritoneal neoplasms

,

nasopharyngeal neoplasms

,

,

,

,

,

,

,

,

haemophilus infections

,

,

,

,

squamous cell carcinoma of head and neck

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