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Company ReportsAcelyrin

Acelyrin(SLRN)

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

,

,

,

psoriatic arthritis

,

,

hidradenitis suppurativa

Bos taurus adrenal cortex corticosteroids

pathologic dilatation

,

cardiac arrhythmias

,

intestinal diseases

,

therapeutic equivalency

,

precancerous conditions

,

,

friedreich ataxia

,

retinal perforations

,

,

,

,

innate immunity

,

immunoglobulin light-chain amyloidosis

,

monoclonal gammopathy of undetermined significance

,

pharmacokinetics

,

pharmacological phenomena

,

,

coronary aneurysm

,

raynaud disease

,

,

cerebellar ataxia

,

,

allergic contact dermatitis

,

,

biological availability

,

drug hypersensitivity syndrome

,

asymptomatic diseases

,

,

retinal telangiectasis

,

closed fractures

,

radius fractures

,

,

stevens-johnson syndrome

,

facial nerve injuries

,

peripheral nerve injuries

,

gastrointestinal diseases

,

myeloproliferative disorders

,

myelodysplastic-myeloproliferative diseases

,

mantle-cell lymphoma

,

t-cell lymphoma

,

b-cell lymphoma marginal zone

,

myeloid leukemia chronic-phase

,

myelomonocytic leukemia chronic

,

t-cell lymphoma peripheral

,

ovarian neoplasms

,

myeloid leukemia accelerated phase

,

,

,

immunoblastic lymphadenopathy

,

,

myelomonocytic leukemia juvenile

,

t-cell lymphoma cutaneous

,

congenital abnormalities

,

primary myelofibrosis

,

waldenstrom macroglobulinemia

,

fanconi syndrome

,

sezary syndrome

,

mycosis fungoides

,

b-cell leukemia

,

,

reperfusion injury

,

,

nasopharyngeal neoplasms

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

,

type 1 diabetes mellitus

,

extranodal nk-t-cell lymphoma

,

refractory anemia with excess of blasts

,

autoimmune diseases

,

ovarian epithelial carcinoma

,

nasopharyngeal carcinoma

,

head and neck neoplasms

,

intestinal neoplasms

,

immunologic deficiency syndromes

,

t-cell leukemia

,

enteropathy-associated t-cell lymphoma

,

,

lymphoproliferative disorders

,

plasmablastic lymphoma

,

refractory anemia

,

prolymphocytic leukemia

,

essential thrombocythemia

,

neutrophilic leukemia chronic

,

glucose intolerance

,

promyelocytic leukemia acute

,

,

amyotrophic lateral sclerosis

,

immune system diseases

,

heart valve diseases

,

,

reactive arthritis

,

,

chronic granulomatous disease

,

leukocyte-adhesion deficiency syndrome

,

erythema nodosum

,

diamond-blackfan anemia

,

,

,

thymus neoplasms

,

adult t-cell leukemia-lymphoma

,

magnetic resonance imaging

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

erythroblastic leukemia acute

,

lymphomatoid granulomatosis

,

,

hematologic diseases

,

polycythemia vera

,

large granular lymphocytic leukemia

,

peritoneal neoplasms

,

digeorge syndrome

,

,

bone marrow failure disorders

,

,

hemangioendothelioma

,

pulmonary arterial hypertension

,

,

,

leukemia myeloid chronic atypical bcr-abl negative

,

gestational trophoblastic disease

,

testicular neoplasms

,

trophoblastic neoplasms

,

hairy cell leukemia

,

,

pure red-cell aplasia

,

leukocytoclastic vasculitis cutaneous

,

male genital neoplasms

,

paroxysmal hemoglobinuria

,

optic nerve injuries

,

endometrial neoplasms

,

post-cardiac arrest syndrome

,

squamous cell neoplasms

,

chronic chemical and drug induced liver injury

,

,

atherosclerosis

,

intranasal administration

,

myocardial infarction

,

paranasal sinus diseases

,

,

neuromuscular diseases

,

radiation injuries

,

bone marrow transplantation

,

homologous transplantation

,

autologous transplantation

,

aphthous stomatitis

,

blastic plasmacytoid dendritic cell neoplasm

,

small cell lung carcinoma

,

rhabdomyosarcoma

,

,

,

,

animal mammary neoplasms

,

gastrointestinal stromal tumors

,

,

,

gastroenteritis

,

renal cell carcinoma

,

spondylarthropathies

,

pheochromocytoma

,

adult-onset still's disease

,

primary immunodeficiency diseases

,

,

,

hiv seropositivity

,

,

intraocular lymphoma

,

,

plasma cell leukemia

,

epidermolysis bullosa

,

intestinal obstruction

,

,

hypoparathyroidism

,

phenylketonurias

,

mast-cell leukemia

,

h1n1 subtype influenza a virus

,

psychotic affective disorders

,

obsessive-compulsive disorder

,

compulsive behavior

,

paranoid schizophrenia

,

lysosomal storage diseases

,

nervous system diseases

,

stiff-person syndrome

,

frontotemporal dementia

,

epithelioid hemangioendothelioma

,

arteriovenous malformations

,

fallopian tube neoplasms

,

,

aids-related lymphoma

,

salivary gland neoplasms

,

,

,

mucopolysaccharidosis vi

,

mucopolysaccharidoses

,

mucopolysaccharidosis i

,

alpha-mannosidosis

,

,

mannosidase deficiency diseases

,

neurotoxicity syndromes

,

triple negative breast neoplasms

,

,

ovarian hyperstimulation syndrome

,

nervous system trauma

,

squamous cell carcinoma of head and neck

,

squamous cell carcinoma

,

ventilator-associated pneumonia

,

drug resistant epilepsy

,

oropharyngeal neoplasms

,

cranial nerve diseases

,

limb-girdle muscular dystrophies

,

leber congenital amaurosis

,

laryngostenosis

,

acanthamoeba keratitis

,

,

hypercholesterolemia

,

opioid-related disorders

,

cocaine-related disorders

,

,

memory disorders

,

,

,

,

,

noise-induced hearing loss

,

pelvic girdle pain

,

pathologic processes

,

,

hantavirus pulmonary syndrome

,

hantavirus infections

,

glycogen storage disease

,

hepatic encephalopathy

,

radiodermatitis

,

,

stomach neoplasms

,

biliary tract neoplasms

,

neoadjuvant therapy

,

dna repair-deficiency disorders

,

intussusception

,

myocardial reperfusion injury

,

,

otorhinolaryngologic diseases

,

unilateral hearing loss

,

,

cognition disorders

,

postpartum depression

,

,

depressive disorder

,

meningoencephalitis

,

central nervous system tuberculosis

,

no-reflow phenomenon

,

paraneoplastic syndromes

,

geographic atrophy

,

chondrocalcinosis

,

,

tendon injuries

,

,

,

nutrition assessment

,

structural myopathies congenital

,

subarachnoid hemorrhage

,

coronary artery disease

,

mandibular fractures

,

,

muscular atrophy

,

cardiogenic shock

,

,

trigeminal neuralgia

,

chronic fatigue syndrome

,

,

graft vs host disease

,

large b-cell lymphoma diffuse

,

non-hodgkin lymphoma

,

myelodysplastic syndromes

,

b-cell lymphoma

,

plasma cell neoplasms

,

,

b-cell chronic lymphocytic leukemia

,

myeloid leukemia acute

,

alcoholic hepatitis

,

,

aplastic anemia

,

,

neoplasm metastasis

,

hematologic neoplasms

,

,

large-cell lymphoma immunoblastic

,

,

myeloid leukemia

,

,

,

bronchiolitis obliterans syndrome

,

chronic progressive multiple sclerosis

,

idiopathic pulmonary fibrosis

,

biphenotypic leukemia acute

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

,

pulmonary fibrosis

,

allergic bronchopulmonary aspergillosis

,

optic nerve diseases

,

viral pneumonia

,

,

,

,

acquired immunodeficiency syndrome

,

,

,

spinal cord injuries

,

post-acute covid-19 syndrome

,

,

focal segmental glomerulosclerosis

,

hip osteoarthritis

,

intervertebral disc displacement

,

deglutition disorders

,

interdigitating dendritic cell sarcoma

,

autoimmune diseases of the nervous system

,

,

dermatomyositis

,

open-angle glaucoma

,

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

critical illness

,

mucocutaneous lymph node syndrome

,

liver neoplasms

,

end stage liver disease

,

langerhans-cell histiocytosis

,

,

,

,

,

,

pulmonary aspergillosis

,

hemolytic anemia autoimmune

,

,

,

,

ischemic optic neuropathy

,

hepatocellular carcinoma

,

organ transplantation

,

,

sickle cell anemia

,

urinary tract infections

,

,

systemic vasculitis

,

gaucher disease

,

kasabach-merritt syndrome

,

,

takayasu arteritis

,

,

hemolytic anemia

,

,

urogenital neoplasms

,

peripheral nervous system diseases

,

,

coronaviridae infections

,

nidovirales infections

,

rna virus infections

,

congenital heart defects

,

,

transverse myelitis

,

alcoholic liver diseases

,

ankylosing spondylitis

,

,

contact dermatitis

,

diabetes insipidus

,

biliary atresia

,

secondary headache disorders

,

,

cardiomyopathies

,

,

autoimmune thyroiditis

,

tendon entrapment

,

hyperlipoproteinemia type i

,

retinal vasculitis

,

,

,

,

,

,

dyskeratosis congenita

,

hashimoto disease

,

adenoviridae infections

,

macrophage activation syndrome

,

spontaneous remission

,

aortic arch syndromes

,

respiratory tract diseases

,

,

,

immunocompromised host

,

,

bacterial pneumonia

,

,

vision disorders

,

spinal cord diseases

,

hyperthyroidism

,

ornithine carbamoyltransferase deficiency disease

,

vascular remodeling

,

spondylarthritis

,

,

seborrheic dermatitis

,

,

meniere disease

,

laryngeal edema

,

prescription drug overuse

,

st elevation myocardial infarction

,

meningeal tuberculosis

,

venous thrombosis

,

human herpesvirus 4

,

postherpetic neuralgia

,

central nervous system neoplasms

,

immunoglobulin variable region

,

chorioretinitis

,

,

adrenogenital syndrome

,

,

,

idiopathic interstitial pneumonias

,

bronchopulmonary dysplasia

,

posterior uveitis

,

,

graft vs host reaction

,

benign mucous membrane pemphigoid

,

intermediate uveitis

,

diabetes complications

,

neurogenic arthropathy

,

,

neuronal ceroid-lipofuscinoses

,

,

globoid cell leukodystrophy

,

metachromatic leukodystrophy

,

niemann-pick diseases

,

type a niemann-pick disease

,

adrenoleukodystrophy

,

,

inborn errors metabolism

,

tay-sachs disease

,

sandhoff disease

,

gm1 gangliosidosis

,

type c niemann-pick disease

,

pick disease of the brain

,

,

,

bites and stings

,

,

orbital pseudotumor

,

vocal cord paralysis

,

,

,

eosinophilic granuloma

,

hypereosinophilic syndrome

,

subdural hematoma

,

subdural hematoma chronic

,

orthostatic intolerance

,

hepatorenal syndrome

,

nontuberculous mycobacterium infections

,

respiration disorders

,

,

,

,

tuberculous pericarditis

,

intracranial hemorrhages

,

diffuse cerebral sclerosis of schilder

,

encephalomyelitis

,

acute disseminated encephalomyelitis

,

aids-related opportunistic infections

,

,

finger injuries

,

dilated cardiomyopathy

,

sudden death cardiac

,

left ventricular dysfunction

,

ventricular remodeling

,

microvascular angina

,

exercise tolerance

,

myelin oligodendrocyte glycoprotein antibody-associated disease

,

sjogren's syndrome

,

language disorders

,

toxic optic neuropathy

,

erythropoietic protoporphyria

,

glucose metabolism disorders

,

glycogen storage disease type i

,

,

erythema multiforme

,

ventricular dysfunction

,

anterior cruciate ligament injuries

,

pyoderma gangrenosum

,

x-linked bulbo-spinal atrophy

,

cerebral infarction

,

postthrombotic syndrome

,

acute-on-chronic liver failure

,

acoustic neuroma

,

,

human adenovirus infections

,

human influenza

,

,

,

,

subacute thyroiditis

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

prostatic neoplasms

,

,

rheumatoid arthritis

,

,

kidney transplantation

,

,

,

multiple sclerosis

,

,

multiple myeloma

,

,

,

,

lymphoid leukemia

,

,

graves ophthalmopathy

,

follicular lymphoma

,

knee osteoarthritis

,

lupus nephritis

,

,

kidney diseases

,

hodgkin disease

,

postoperative pain

,

,

systemic lupus erythematosus

,

nephrotic syndrome

,

castration-resistant prostatic neoplasms

,

chronic obstructive pulmonary disease

,

,

,

iga glomerulonephritis

,

burkitt lymphoma

,

,

,

neuromyelitis optica

,

healthy volunteers/patients

,

,

,

,

adrenal insufficiency

,

hemophagocytic lymphohistiocytosis

,

relapsing-remitting multiple sclerosis

,

respiratory distress syndrome

,

membranous glomerulonephritis

,

glomerulonephritis

,

polymyalgia rheumatica

,

chronic kidney failure

,

,

giant cell arteritis

,

graft rejection

,

renal insufficiency

,

,

,

ulcerative colitis

,

thrombocytopenic purpura idiopathic

,

,

,

obstructive lung diseases

,

disease progression

,

large-cell lymphoma anaplastic

,

,

carpal tunnel syndrome

,

breast neoplasms

,

,

hypersensitivity

,

,

,

granulomatosis with polyangiitis

,

community-acquired pneumonia

,

coronavirus infections

,

diabetes mellitus

,

chronic renal insufficiency

,

postoperative complications

,

liver transplantation

,

immunosuppression therapy

,

replacement arthroplasty knee

,

,

,

sudden hearing loss

,

lipoid nephrosis

,

,

,

,

autoimmune hepatitis

,

,

facial paralysis

,

,

microscopic polyangiitis

,

,

,

acute lung injury

,

interstitial lung diseases

,

psychology rejection

,

plantar fasciitis

,

severe acute respiratory syndrome

,

anterior uveitis

,

systemic scleroderma

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

pain management

,

cytokine release syndrome

,

,

,

,

migraine disorders

,

,

pneumocystis pneumonia

,

,

allergic conjunctivitis

,

wounds and injuries

,

,

,

atopic dermatitis

,

communicable diseases

,

,

chemical and drug induced liver injury

,

diffuse scleroderma

,

,

,

ischemic stroke

,

drug-related side effects and adverse reactions

,

intervertebral disc degeneration

,

,

inflammatory bowel diseases

,

muscle weakness

,

retinal diseases

,

thrombocytopenia

,

status asthmaticus

,

postoperative nausea and vomiting

,

infantile spasms

,

insulin resistance

,

,

,

,

sensorineural hearing loss

,

,

newborn respiratory distress syndrome

,

,

type 2 diabetes mellitus

,

epstein-barr virus infections

,

respiratory sounds

,

spinal stenosis

,

dry eye syndromes

,

cataract extraction

,

,

,

,

,

juvenile arthritis

,

,

duchenne muscular dystrophy

,

hepatic insufficiency

,

,

brain neoplasms

,

,

respiratory insufficiency

,

heart transplantation

,

,

,

systemic inflammatory response syndrome

,

thrombocytopenic purpura

,

,

behcet syndrome

,

respiratory tract infections

,

pathologic constriction

,

,

,

immunoglobulin g4-related disease

,

,

shoulder impingement syndrome

,

,

,

esophageal stenosis

,

muscular dystrophies

,

musculoskeletal diseases

,

,

biliary liver cirrhosis

,

myasthenia gravis

,

,

allergic rhinitis

,

,

diabetic retinopathy

,

,

,

,

,

,

psychotic disorders

,

,

thyroid diseases

,

cardiopulmonary bypass

,

out-of-hospital cardiac arrest

,

,

extrinsic allergic alveolitis

,

trigger finger disorder

,

acute liver failure

,

,

,

mycoplasma pneumonia

,

mycoplasma pneumoniae

,

liver cirrhosis

,

parkinson disease

,

cognitive dysfunction

,

thrombotic thrombocytopenic purpura

,

granulomatous mastitis

,

,

,

,

retinal detachment

,

bullous pemphigoid

,

,

congenital adrenal hyperplasia

,

,

,

,

hematopoietic stem cell transplantation

,

churg-strauss syndrome

,

capsule opacification

,

,

,

mental disorders

,

,

bacterial infections

,

keratoconjunctivitis sicca

,

acute kidney injury

,

cardiac surgical procedures

,

ocular hypertension

,

spontaneous abortion

,

habitual abortion

,

failed back surgery syndrome

,

obstructive sleep apnea

,

sleep apnea syndromes

,

vestibular neuronitis

,

herpetic keratitis

,

,

aortic dissection

,

multiple organ failure

,

alopecia areata

,

,

psoriatic arthritis

,

,

delayed graft function

,

restless legs syndrome

,

post-concussion syndrome

,

retinal vein occlusion

,

macular degeneration

,

,

,

cytomegalovirus infections

,

meibomian gland dysfunction

,

treatment outcome

,

patient preference

,

corneal transplantation

,

,

intraocular pressure

,

epiretinal membrane

,

vitreoretinal surgery

,

,

refractive surgical procedures

,

drug interactions

,

demyelinating diseases

,

,

polyarteritis nodosa

,

chronic disease

,

interstitial nephritis

,

,

,

,

retroperitoneal fibrosis

,

muscular diseases

,

post-traumatic headache

,

,

,

otitis media with effusion

,

allergic rhinitis seasonal

,

aortic valve stenosis

,

patient satisfaction

,

pulmonary eosinophilia

,

patient compliance

,

cluster headache

,

facial nerve diseases

,

,

pulmonary sarcoidosis

,

oral lichen planus

,

,

rotator cuff tear arthropathy

,

aortic aneurysm

,

fuchs' endothelial dystrophy

,

atrial fibrillation

,

chronic hepatitis b

,

chronic hepatitis

,

,

,

connective tissue diseases

,

bundle-branch block

,

ultrasonography

,

intra-articular injections

,

,

,

cerebral hemorrhage

,

renal replacement therapy

,

rh isoimmunization

,

neurosurgical procedures

,

elbow fractures

,

penetrating keratoplasty

,

,

,

viral encephalitis

,

wrist fractures

,

orthopedic procedures

,

caregiver burden

,

mediastinal neoplasms

,

,

,

leukoencephalopathies

,

progressive multifocal leukoencephalopathy

,

immune reconstitution inflammatory syndrome

,

,

,

transplantation

,

,

neuromuscular monitoring

,

intraoperative complications

,

,

,

,

rolandic epilepsy

,

corneal diseases

,

severe acute respiratory syndrome-related coronavirus

,

lacrimal apparatus diseases

,

borrelia infections

,

,

vitamin a deficiency

,

night blindness

,

corneal opacity

,

vestibular diseases

,

tracheal stenosis

,

operative surgical procedures

,

viral bronchiolitis

,

polycystic ovary syndrome

,

thoracic aortic aneurysm

,

thoracoabdominal aortic aneurysm

,

,

,

physiological stress

,

barrett esophagus

,

esophageal diseases

,

,

chronic bronchitis

,

pituitary diseases

,

fertilization in vitro

,

,

pudendal neuralgia

,

,

bacterial eye infections

,

optic disk drusen

,

regional blood flow

,

,

,

severe fever with thrombocytopenia syndrome

,

,

neoplasms by histologic type

,

dupuytren contracture

,

,

connective and soft tissue neoplasms

,

connective tissue neoplasms

,

,

fibrous tissue neoplasms

,

esophageal neoplasms

,

,

,

,

aortic valve disease

,

medication adherence

,

arteriosclerosis

,

guillain-barre syndrome

,

,

,

nasal obstruction

,

transcatheter aortic valve replacement

,

traumatic brain injuries

,

,

food hypersensitivity

,

cerebrovascular disorders

,

hemorrhagic stroke

,

intracranial aneurysm

,

musculoskeletal pain

,

,

spine osteoarthritis

,

,

rotator cuff injuries

,

,

uveomeningoencephalitic syndrome

,

mycoplasma infections

,

pleuropneumonia

,

keratoconjunctivitis

,

,

,

,

,

,

,

lymph node tuberculosis

,

delayed emergence from anesthesia

,

,

primary headache disorders

,

lung transplantation

,

hypertrophic cicatrix

,

,

,

chronic urticaria

,

,

,

drug hypersensitivity

,

,

non-alcoholic fatty liver disease

,

,

herpesviridae infections

,

,

venous thromboembolism

,

thromboembolism

,

blood coagulation

,

neuroinflammatory diseases

,

wiskott-aldrich syndrome

,

severe combined immunodeficiency

,

agammaglobulinemia

,

type 1 hyper-igm immunodeficiency syndrome

,

chediak-higashi syndrome

,

common variable immunodeficiency

,

hyper-igm immunodeficiency syndrome

,

pathologic complete response

,

secondary hyperparathyroidism

,

,

post-dural puncture headache

,

,

hyperaldosteronism

,

,

sleep initiation and maintenance disorders

,

intraabdominal infections

,

healthcare-associated pneumonia

,

methicillin-resistant staphylococcus aureus

,

,

staphylococcal infections

,

general anesthesia

,

gram-negative bacterial infections

,

bacterial meningitis

,

,

central nervous system infections

,

neuromuscular blockade

,

,

,

cytomegalovirus retinitis

,

port-wine stain

,

,

,

capillary hemangioma

,

bipolar disorder

,

autistic disorder

,

,

,

treatment-resistant schizophrenia

,

potassium deficiency

,

,

male genital diseases

,

genital diseases

,

exfoliation syndrome

,

,

,

cardiac conduction system disease

,

benign paroxysmal positional vertigo

,

,

choroid diseases

,

,

localized scleroderma

,

,

,

hypoventilation

,

,

acupuncture therapy

,

dentofacial deformities

,

malignant mesothelioma

,

cochlear implants

,

,

rheumatic diseases

,

rheumatic fever

,

collagen diseases

,

,

,

,

,

femur head necrosis

,

disease susceptibility

,

angle-closure glaucoma

,

,

tissue adhesions

,

,

scleral buckling

,

,

cardiovascular diseases

,

cardiovascular abnormalities

,

orthostatic hypotension

,

,

foot and mouth disease hand

,

,

electroretinography

,

abdominal aortic aneurysm

,

low cardiac output

,

,

pleural tuberculosis

,

corneal neovascularization

,

pathologic neovascularization

,

pediatric obesity

,

esophageal squamous cell carcinoma

,

root canal obturation

,

,

interstitial cystitis

,

,

somatoform disorders

,

cartilage diseases

,

pancreatic neoplasms

,

,

intravenous administration

,

nociceptive pain

,

,

,

intracranial thrombosis

,

,

,

pneumocystis infections

,

,

transcranial direct current stimulation

,

double-blind method

,

,

organ dysfunction scores

,

femoracetabular impingement

,

local anesthesia

,

drug-induced abnormalities

,

respiratory aspiration

,

noninvasive ventilation

,

lymphadenopathy

,

cushing syndrome

,

sleep wake disorders

,

,

,

angina pectoris

,

variant angina pectoris

,

radiofrequency ablation

,

hypoalbuminemia

,

,

hyperbilirubinemia

,

recovery of function

,

cns demyelinating autoimmune diseases

,

,

four-dimensional computed tomography

,

emergence delirium

,

,

,

addison disease

,

blood glucose self-monitoring

,

,

shoulder injuries

,

,

phacoemulsification

,

altitude sickness

,

,

pulmonary edema

,

prediabetic state

,

,

,

,

palliative care

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