Valacyclovir
Valacyclovir, Valtrex (valacyclovir) is a small molecule pharmaceutical. Valacyclovir was first approved as Valtrex on 1995-06-23. It is used to treat chickenpox, herpes genitalis, herpes labialis, herpes simplex, and herpes zoster in the USA.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Valacyclovir, Valtrex (discontinued: Valacyclovir)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| acyclovir valacyclovir valacyclovir hydrochloride | ANDA | 2023-06-29 |
| direct rx | ANDA | 2015-11-09 |
| valacyclovir | ANDA | 2026-08-28 |
| valacyclovir hydrochloride | ANDA | 2026-08-13 |
| valacyclovir valacyclovir | ANDA | 2026-02-18 |
| valacyclovir valacyclovir hydrochloride | ANDA | 2020-06-17 |
| valtrex | New Drug Application | 2026-07-16 |
Indications
FDA
EMA
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
147 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | PhĀ 1 | PhĀ 2 | PhĀ 3 | PhĀ 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Herpes simplex | D006561 | ā | B00 | 9 | 13 | 11 | 10 | 10 | 53 |
| Herpes zoster | D006562 | EFO_0006510 | B02 | 2 | 5 | 4 | 3 | 8 | 22 |
| Infections | D007239 | EFO_0000544 | ā | 5 | 3 | 5 | 4 | 5 | 20 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 1 | 2 | 6 | 3 | 6 | 18 |
| Communicable diseases | D003141 | ā | ā | 5 | 3 | 3 | 3 | 5 | 17 |
| Herpes genitalis | D006558 | EFO_0007282 | A60 | ā | 4 | 2 | 5 | 4 | 15 |
| Virus diseases | D014777 | ā | B34 | 2 | ā | ā | 4 | 2 | 8 |
| Cytomegalovirus infections | D003586 | EFO_0001062 | B25 | ā | 3 | 2 | 2 | 1 | 7 |
| Varicella zoster virus infection | D000073618 | ā | ā | 1 | ā | ā | 1 | 2 | 4 |
| Herpesviridae infections | D006566 | EFO_0007309 | B00.4 | ā | ā | ā | 1 | 3 | 4 |
Show 15 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | PhĀ 1 | PhĀ 2 | PhĀ 3 | PhĀ 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Prostatic neoplasms | D011471 | ā | C61 | 1 | 4 | 1 | ā | ā | 5 |
| Non-small-cell lung carcinoma | D002289 | ā | ā | ā | 3 | 1 | ā | ā | 4 |
| Chickenpox | D002644 | EFO_0007204 | B01 | 1 | ā | 1 | ā | 2 | 4 |
| Postherpetic neuralgia | D051474 | ā | ā | ā | 1 | 2 | ā | 1 | 4 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | ā | ā | 3 | ā | ā | 3 |
| Neuralgia | D009437 | EFO_0009430 | ā | ā | 1 | 1 | ā | 1 | 3 |
| Cognitive dysfunction | D060825 | ā | G31.84 | ā | 2 | 1 | ā | ā | 3 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | ā | 2 | 1 | ā | ā | 3 |
| Hiv | D006678 | ā | O98.7 | ā | ā | 1 | ā | 2 | 3 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | 1 | ā | 1 | ā | 1 | 3 |
Show 8 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | PhĀ 1 | PhĀ 2 | PhĀ 3 | PhĀ 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glioblastoma | D005909 | EFO_0000515 | ā | 6 | 4 | ā | ā | ā | 7 |
| Glioma | D005910 | EFO_0000520 | ā | 4 | 1 | ā | ā | ā | 5 |
| Lung neoplasms | D008175 | ā | C34.90 | 2 | 3 | ā | ā | ā | 5 |
| Epstein-barr virus infections | D020031 | EFO_0000769 | ā | ā | 2 | ā | ā | 2 | 4 |
| Astrocytoma | D001254 | EFO_0000271 | ā | 3 | 3 | ā | ā | ā | 4 |
| Hepatitis c | D006526 | ā | B19.2 | 2 | 1 | ā | ā | ā | 3 |
| Chronic hepatitis c | D019698 | EFO_0004220 | B18.2 | 2 | 1 | ā | ā | ā | 3 |
| Hepatitis | D006505 | ā | K75.9 | 2 | 1 | ā | ā | ā | 3 |
| Hepatitis a | D006506 | EFO_0007305 | B15 | 2 | 1 | ā | ā | ā | 3 |
| Head and neck neoplasms | D006258 | ā | ā | 1 | 1 | ā | ā | ā | 2 |
Show 26 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | PhĀ 1 | PhĀ 2 | PhĀ 3 | PhĀ 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | ā | ā | ā | 8 | ā | ā | ā | 3 | 11 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | 2 | ā | ā | ā | 1 | 3 |
| Infectious pregnancy complications | D011251 | ā | ā | 1 | ā | ā | ā | ā | 1 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 1 | ā | ā | ā | ā | 1 |
| Pleural effusion | D010996 | ā | J90 | 1 | ā | ā | ā | ā | 1 |
| Mesothelioma | D008654 | ā | C45 | 1 | ā | ā | ā | ā | 1 |
| Malignant pleural effusion | D016066 | ā | J91.0 | 1 | ā | ā | ā | ā | 1 |
| Hepatitis b | D006509 | ā | ā | 1 | ā | ā | ā | ā | 1 |
| Coinfection | D060085 | ā | ā | 1 | ā | ā | ā | ā | 1 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | ā | ā | ā | ā | 1 |
Show 8 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | PhĀ 1 | PhĀ 2 | PhĀ 3 | PhĀ 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Paralysis | D010243 | ā | ā | ā | ā | ā | ā | 2 | 2 |
| Acne vulgaris | D000152 | EFO_0003894 | L70 | ā | ā | ā | ā | 1 | 1 |
| Hypertrophy | D006984 | EFO_0002460 | ā | ā | ā | ā | ā | 1 | 1 |
| Recurrence | D012008 | ā | ā | ā | ā | ā | ā | 1 | 1 |
| Bacterial vaginosis | D016585 | EFO_0003932 | ā | ā | ā | ā | ā | 1 | 1 |
| Vaginal diseases | D014623 | ā | ā | ā | ā | ā | ā | 1 | 1 |
| Immunologic deficiency syndromes | D007153 | ā | D84.9 | ā | ā | ā | ā | 1 | 1 |
| Oncogenes | D009857 | ā | ā | ā | ā | ā | ā | 1 | 1 |
| Electroacupuncture | D015671 | ā | ā | ā | ā | ā | ā | 1 | 1 |
| Periapical periodontitis | D010485 | EFO_1001391 | K04.5 | ā | ā | ā | ā | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Valacyclovir |
| INN | valaciclovir |
| Description | Valacyclovir is a L-valyl ester. It has a role as an antiviral drug. It is functionally related to a guanine. |
| Classification | Small molecule |
| Drug class | antivirals: antivirals (acyclovir type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)[C@H](N)C(=O)OCCOCn1cnc2c(=O)nc(N)[nH]c21 |
Identifiers
| PDB | ā |
| CAS-ID | 124832-26-4 |
| RxCUI | ā |
| ChEMBL ID | CHEMBL1349 |
| ChEBI ID | 35854 |
| PubChem CID | 135398742 |
| DrugBank | DB00577 |
| UNII ID | MZ1IW7Q79D (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
Revenue by drug
$
ā¬
Ā£
ā£
No data
Estimated US medical usage
Valacyclovir
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 9,602 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
24,039 adverse events reported
View more details
Ā© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use