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Drug ReportsVARLILUMAB
VARLILUMAB
Varlilumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target CD27 antigen.
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Clinical
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Variants
Financial
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Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
CarcinomaD002277—C80.042———5
MelanomaD008545——43———5
Renal cell carcinomaD002292EFO_0000376—41———4
LymphomaD008223—C85.922———3
B-cell lymphomaD016393——22———3
RecurrenceD012008———2———2
Burkitt lymphomaD002051—C83.711———2
GlioblastomaD005909EFO_0000515—12———2
AdenocarcinomaD000230——11———2
Non-hodgkin lymphomaD008228—C85.9—1———1
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Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD002289——3————3
NeoplasmsD009369—C803————3
Kidney diseasesD007674EFO_0003086N082————2
Urologic neoplasmsD014571—C64-C682————2
Urogenital neoplasmsD014565EFO_0003863D072————2
Kidney neoplasmsD007680EFO_0003865C642————2
Urologic diseasesD014570—N39.92————2
Neoplasms by histologic typeD009370——2————2
Ovarian neoplasmsD010051EFO_0003893C562————2
Lung neoplasmsD008175HP_0100526C34.901————1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameVARLILUMAB
INNvarlilumab
Description
Varlilumab (human mab)
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID—
RxCUI—
ChEMBL IDCHEMBL3137347
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID0125DUV5XC (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CD27
CD27
Organism
Homo sapiens
Gene name
CD27
Gene synonyms
TNFRSF7
NCBI Gene ID
Protein name
CD27 antigen
Protein synonyms
CD27, CD27L receptor, T cell activation antigen S152, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, tumor necrosis factor receptor superfamily, member 7
Uniprot ID
Mouse ortholog
Cd27 (21940)
CD27 antigen (P41272)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 368 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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43 adverse events reported
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