Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Adenocarcinoma | D000230 | — | — | 3 | 4 | — | — | — | 5 |
Stomach neoplasms | D013274 | EFO_0003897 | C16 | 3 | 4 | — | — | — | 5 |
Colorectal neoplasms | D015179 | — | — | 2 | 2 | — | — | — | 3 |
Neoplasms | D009369 | — | C80 | 2 | 1 | — | — | — | 3 |
Esophageal neoplasms | D004938 | — | C15 | 2 | 2 | — | — | — | 3 |
Non-small-cell lung carcinoma | D002289 | — | — | 1 | 2 | — | — | — | 2 |
Aggressive fibromatosis | D018222 | — | D48.11 | 1 | 2 | — | — | — | 2 |
Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 2 | 1 | — | — | — | 2 |
Myeloproliferative disorders | D009196 | — | D47.1 | 1 | 1 | — | — | — | 2 |
Urologic neoplasms | D014571 | — | C64-C68 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Multiple myeloma | D009101 | — | C90.0 | 2 | — | — | — | — | 2 |
Myelodysplastic syndromes | D009190 | — | D46 | 2 | — | — | — | — | 2 |
Syndrome | D013577 | — | — | 2 | — | — | — | — | 2 |
Plasma cell neoplasms | D054219 | — | — | 1 | — | — | — | — | 1 |
Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Preleukemia | D011289 | — | — | 1 | — | — | — | — | 1 |
Leukemia | D007938 | — | C95 | 1 | — | — | — | — | 1 |
Myeloid leukemia acute | D015470 | — | C92.0 | 1 | — | — | — | — | 1 |
Hematologic neoplasms | D019337 | — | — | 1 | — | — | — | — | 1 |
Non-hodgkin lymphoma | D008228 | — | C85.9 | 1 | — | — | — | — | 1 |
Drug common name | VACTOSERTIB |
INN | vactosertib |
Description | Vactosertib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against activin receptor type-1B and TGF-beta receptor type-1. |
Classification | Small molecule |
Drug class | serine/threonine kinase inhibitors |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | Cc1cccc(-c2[nH]c(CNc3ccccc3F)nc2-c2ccc3ncnn3c2)n1 |
PDB | — |
CAS-ID | 1352608-82-2 |
RxCUI | — |
ChEMBL ID | CHEMBL3260567 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | — |
UNII ID | 6T4O391P5Y (ChemIDplus, GSRS) |