Triclosan
Colgate Total (triclosan) is a small molecule pharmaceutical. Triclosan was first approved as Colgate total on 1997-07-11. It is used to treat bacterial infections and mycoses in the USA.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Sodium fluoride
+
Triclosan
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| COLGATE TOTAL | Colgate-Palmolive | N-020231 DISCN | 1997-07-11 | 1 products, RLD |
Hide discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| aeroscent milk and honey antibacterial moisturizing | OTC monograph not final | 2015-06-23 |
| aire-master | OTC monograph not final | 2020-01-29 |
| all day freshness antibacterial body wash with moisturizer gold antibacterial hand soap with moisturizer | OTC monograph not final | 2010-06-03 |
| anti-bacterial blue raspberry hand | OTC monograph not final | 2012-10-06 |
| anti-bacterial bubble gum hand | OTC monograph not final | 2012-11-30 |
| anti-bacterial foaming | OTC monograph not final | 2011-08-12 |
| anti-bacterial fresh aloe hand | OTC monograph not final | 2013-08-20 |
| anti-bacterial lemon drop hand | OTC monograph not final | 2012-10-06 |
| anti-bacterial moisturizing hand | OTC monograph not final | 2012-04-03 |
| anti-bacterial strawberry kiss hand | OTC monograph not final | 2012-10-06 |
Show 302 more
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| bacterial infections and mycoses | — | D001423 | — |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
— D08: Antiseptics and disinfectants
— D08A: Antiseptics and disinfectants
— D08AE: Phenol and derivatives, antiseptics and disinfectants
— D08AE04: Triclosan
— D09: Medicated dressings
— D09A: Medicated dressings
— D09AA: Medicated dressings with antiinfectives
— D09AA06: Triclosan
HCPCS
No data
Clinical
Clinical Trials
85 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dental plaque | D003773 | — | — | — | 2 | 11 | 3 | — | 16 |
| Gingivitis | D005891 | — | K05.10 | — | 1 | 3 | 5 | — | 9 |
| Periodontal diseases | D010510 | — | K05.6 | — | — | 2 | 1 | 1 | 4 |
| Inflammation | D007249 | MP_0001845 | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Gingival diseases | D005882 | — | K05.1 | — | — | 6 | — | — | 6 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | — | 2 | — | — | 2 |
| Mucositis | D052016 | EFO_1001898 | — | — | — | 1 | — | — | 1 |
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | — | 1 | — | — | 1 |
| Dentin sensitivity | D003807 | — | — | — | — | 1 | — | — | 1 |
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | 1 | — | — | 1 |
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Triclosan |
| INN | triclosan |
| Description | Triclosan is an aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes. It has a role as an antibacterial agent, a fungicide, an EC 1.5.1.3 (dihydrofolate reductase) inhibitor, an antimalarial, an EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor, a xenobiotic, a persistent organic pollutant and a drug allergen. It is a member of phenols, an aromatic ether, a dichlorobenzene and a member of monochlorobenzenes. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl |
Identifiers
| PDB | — |
| CAS-ID | 3380-34-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL849 |
| ChEBI ID | 164200 |
| PubChem CID | 5564 |
| DrugBank | DB08604 |
| UNII ID | 4NM5039Y5X (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 11,571 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
1,106 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use